HighVista Strategies LLC
13F Reported Value
ⓘ$438.6M
Holdings
147
Latest Filing
2026-06-30
Filing Quarter
Q2 2026
Portfolio Overview
HighVista Strategies LLC disclosed 147 positions worth $438.6M in its Form 13F-HR for Q2 2026, led by $DBC (Invesco DB Commodity Index Tracking Fund) at 6.4% of the equity portfolio, followed by $ABVX and $RVMD. During the quarter the fund opened 29 new positions and exited 38 — including a new stake in $CCCC and a full exit from $TERN. The portfolio is most concentrated in Healthcare (70.4% of disclosed assets). All figures are sourced directly from HighVista Strategies LLC’s Form 13F-HR filing with the SEC under CIK 1335325.
AI Fund Analysis
StableSector Allocation
AUM History
Top Equity Holdings by Value
Quarterly Activity — Q2 2026
Click any card to unlockTop Holdings
- $28.2M1,057,238 sh
- —
Quality
$15.1M113,031 sh - —
Quality
$12.5M66,983 sh - —
Quality
$11.4M242,884 sh - —
Quality
$10.7M277,873 sh - $10.1M30,210 sh
- 19.5
Quality
$9.5M506,235 sh - —
Quality
$9.4M179,256 sh - —
Quality
$8.7M149,739 sh - 17.6
Quality
$8.1M260,070 sh
| Company | Quality | Value | Shares |
|---|---|---|---|
 Invesco DB Commodity Index Tracking Fund$DBC | — | $28.2M | 1,057,238 |
 Abivax S.A.$ABVX | — | $15.1M | 113,031 |
 Revolution Medicines, Inc.$RVMD | — | $12.5M | 66,983 |
 Definium Therapeutics, Inc.$DFTX | — | $11.4M | 242,884 |
 Immunovant, Inc.$IMVT | — | $10.7M | 277,873 |
 Praxis Precision Medicines, Inc.$PRAX | — | $10.1M | 30,210 |
 Relay Therapeutics, Inc.$RLAY | 19.5 | $9.5M | 506,235 |
 Alkermes plc.$ALKS | — | $9.4M | 179,256 |
 Vaxcyte, Inc.$PCVX | — | $8.7M | 149,739 |
 Tango Therapeutics, Inc.$TNGX | 17.6 | $8.1M | 260,070 |
Unlock AI quality scores for every holding
32-signal composite ranking on each of HighVista Strategies LLC's 147 positions.
Showing top 10 of 147 holdings.
Sector Allocation
Healthcare
$309.0M
Financials
$42.1M
Technology
$35.8M
Industrials
$17.8M
Consumer Discretionary
$13.3M
Utilities
$9.3M
Energy
$5.8M
Materials
$3.9M
Full Holdings — HighVista Strategies LLC (Q2 2026)
All 147 disclosed positions from the latest Form 13F-HR, with quarter-over-quarter share changes and 13F Pro quality scores. Sourced from SEC EDGAR.
| # | Ticker | Company | Value | Weight | QoQ | Quality |
|---|---|---|---|---|---|---|
| 1 | $DBC | Invesco DB Commodity Index Tracking Fund | $28.2M | 6.4% | +0% | — |
| 2 | $ABVX | Abivax S.A. | $15.1M | 3.4% | -0% | — |
| 3 | $RVMD | Revolution Medicines, Inc. | $12.5M | 2.9% | -3% | — |
| 4 | $DFTX | Definium Therapeutics, Inc. | $11.4M | 2.6% | +31% | — |
| 5 | $IMVT | Immunovant, Inc. | $10.7M | 2.4% | +23% | — |
| 6 | $PRAX | Praxis Precision Medicines, Inc. | $10.1M | 2.3% | +15% | — |
| 7 | $RLAY | Relay Therapeutics, Inc. | $9.5M | 2.2% | +20% | 19.5 |
| 8 | $ALKS | Alkermes plc. | $9.4M | 2.1% | +145% | — |
| 9 | $PCVX | Vaxcyte, Inc. | $8.7M | 2.0% | +20% | — |
| 10 | $TNGX | Tango Therapeutics, Inc. | $8.1M | 1.9% | +150% | 17.6 |
| 11 |  $LQDA | Liquidia Corp | $7.8M | 1.8% | -2% | 78.3 |
| 12 |  $COGT | Cogent Biosciences, Inc. | $7.3M | 1.7% | -4% | — |
| 13 |  $GPCR | Structure Therapeutics Inc. | $7.0M | 1.6% | +6% | — |
| 14 |  $ELVN | Enliven Therapeutics, Inc. | $7.0M | 1.6% | +89% | — |
| 15 |  $AMLX | Amylyx Pharmaceuticals, Inc. | $6.9M | 1.6% | +10% | 8.7 |
| 16 |  $SYRE | Spyre Therapeutics, Inc. | $6.9M | 1.6% | -47% | — |
| 17 |  $LBRX | LB PHARMACEUTICALS INC | $6.9M | 1.6% | +22% | — |
| 18 |  $CYTK | CYTOKINETICS INC | $6.6M | 1.5% | +33% | 28.1 |
| 19 |  $CCCC | C4 Therapeutics, Inc. | $6.3M | 1.4% | NEW | 18.2 |
| 20 |  $TYRA | Tyra Biosciences, Inc. | $5.9M | 1.4% | +41% | — |
| 21 |  $ALMS | ALUMIS INC. | $5.6M | 1.3% | +77% | 7.1 |
| 22 |  $PHVS | Pharvaris N.V. | $5.5M | 1.3% | +64% | — |
| 23 |  $TARS | Tarsus Pharmaceuticals, Inc. | $5.5M | 1.3% | +66% | 55 |
| 24 |  $CMPS | COMPASS Pathways plc | $5.3M | 1.2% | +2% | — |
| 25 |  $DNTH | Dianthus Therapeutics, Inc. /DE/ | $5.0M | 1.1% | +44% | 22.6 |
| 26 |  $NRIX | Nurix Therapeutics, Inc. | $4.9M | 1.1% | -10% | 6.4 |
| 27 |  $AXSM | Axsome Therapeutics, Inc. | $4.9M | 1.1% | -1% | 40.8 |
| 28 |  $TVTX | Travere Therapeutics, Inc. | $4.9M | 1.1% | +137% | 56.6 |
| 29 |  $VERA | Vera Therapeutics, Inc. | $4.5M | 1.0% | +53% | — |
| 30 |  $NVDA | NVIDIA CORP | $4.4M | 1.0% | -3% | 85.9 |
| 31 |  $GHRS | GH Research PLC | $4.3M | 1.0% | -26% | — |
| 32 |  $PALI | PALISADE BIO, INC. | $4.2M | 1.0% | +1% | — |
| 33 |  $ARGX | ARGENX SE | $4.2M | 1.0% | -7% | — |
| 34 |  $MAZE | Maze Therapeutics, Inc. | $4.1M | 0.9% | +37% | 10.3 |
| 35 |  $OCUL | OCULAR THERAPEUTIX, INC | $4.0M | 0.9% | -7% | 8.4 |
| 36 |  $ORKA | Oruka Therapeutics, Inc. | $4.0M | 0.9% | -47% | — |
| 37 |  $DYN | Dyne Therapeutics, Inc. | $3.8M | 0.9% | -6% | — |
| 38 |  $EWTX | Edgewise Therapeutics, Inc. | $3.7M | 0.8% | -1% | — |
| 39 |  $MLTX | MoonLake Immunotherapeutics | $3.7M | 0.8% | -3% | — |
| 40 |  $INSM | INSMED Inc | $3.3M | 0.8% | +29% | 39.4 |
| 41 |  $CLDX | Celldex Therapeutics, Inc. | $3.2M | 0.7% | -3% | 8.4 |
| 42 |  $AMZN | AMAZON COM INC | $3.2M | 0.7% | -40% | 68.7 |
| 43 |  $IVA | Inventiva S.A. | $3.1M | 0.7% | +35% | — |
| 44 |  $TLN | Talen Energy Corp | $3.1M | 0.7% | +161% | 57.2 |
| 45 |  $RLMD | RELMADA THERAPEUTICS, INC. | $3.1M | 0.7% | NEW | — |
| 46 |  $PTGX | Protagonist Therapeutics, Inc | $3.0M | 0.7% | -28% | 59.4 |
| 47 |  $ERAS | Erasca, Inc. | $2.9M | 0.7% | -11% | — |
| 48 |  $VRDN | Viridian Therapeutics, Inc.\DE | $2.9M | 0.7% | +19% | 27.2 |
| 49 |  $HPE | Hewlett Packard Enterprise Co | $2.7M | 0.6% | -34% | 70.5 |
| 50 |  $MLYS | Mineralys Therapeutics, Inc. | $2.3M | 0.5% | +84% | — |
| 51 |  $GH | Guardant Health, Inc. | $2.3M | 0.5% | -34% | 39 |
| 52 |  $AVTX | Avalo Therapeutics, Inc. | $2.3M | 0.5% | +109% | 11.7 |
| 53 |  $JHX | James Hardie Industries plc | $2.2M | 0.5% | +30% | — |
| 54 |  $EYPT | EyePoint, Inc. | $2.2M | 0.5% | -15% | 3.5 |
| 55 |  $MTZ | MASTEC INC | $2.1M | 0.5% | +42% | 58.8 |
| 56 |  $XENE | Xenon Pharmaceuticals Inc. | $2.1M | 0.5% | -28% | 24 |
| 57 |  $RBC | RBC Bearings INC | $2.1M | 0.5% | +21% | 66.8 |
| 58 |  $V | VISA INC. | $2.0M | 0.5% | -17% | 82.9 |
| 59 |  $ASMB | ASSEMBLY BIOSCIENCES, INC. | $2.0M | 0.5% | -2% | 41.5 |
| 60 |  $STOK | Stoke Therapeutics, Inc. | $2.0M | 0.5% | -2% | 24.9 |
| 61 |  $OLMA | Olema Pharmaceuticals, Inc. | $2.0M | 0.5% | +36% | — |
| 62 |  $RKT | Rocket Companies, Inc. | $2.0M | 0.5% | +36% | 74.2 |
| 63 |  $XPO | XPO, Inc. | $2.0M | 0.5% | +8% | 58.4 |
| 64 |  $WDC | WESTERN DIGITAL CORP | $1.9M | 0.4% | -26% | 80.7 |
| 65 |  $CORZ | Core Scientific, Inc./tx | $1.9M | 0.4% | -27% | 14.1 |
| 66 |  $TXN | TEXAS INSTRUMENTS INC | $1.9M | 0.4% | NEW | 73.4 |
| 67 |  $KBR | KBR, INC. | $1.9M | 0.4% | +38% | 56.2 |
| 68 |  $FLS | FLOWSERVE CORP | $1.9M | 0.4% | +0% | 70.7 |
| 69 |  $GOOGL | Alphabet Inc. | $1.8M | 0.4% | -6% | 78.2 |
| 70 |  $STX | Seagate Technology Holdings plc | $1.8M | 0.4% | -36% | — |
| 71 |  $MIRM | Mirum Pharmaceuticals, Inc. | $1.7M | 0.4% | -4% | 35 |
| 72 |  $DNOW | DNOW Inc. | $1.7M | 0.4% | NEW | 48.8 |
| 73 |  $ON | ON SEMICONDUCTOR CORP | $1.7M | 0.4% | -35% | 55 |
| 74 |  $NUE | NUCOR CORP | $1.7M | 0.4% | NEW | 61.7 |
| 75 |  $TDAY | USA TODAY Co., Inc. | $1.6M | 0.4% | NEW | 37.5 |
| 76 |  $AVGO | Broadcom Inc. | $1.6M | 0.4% | -25% | 84.5 |
| 77 |  $CLMT | Calumet, Inc. /DE | $1.6M | 0.4% | NEW | 40.2 |
| 78 |  $Q | Qnity Electronics, Inc. | $1.6M | 0.4% | NEW | 68.4 |
| 79 |  $KOD | Kodiak Sciences Inc. | $1.6M | 0.4% | -7% | — |
| 80 |  $CRDO | Credo Technology Group Holding Ltd | $1.6M | 0.4% | NEW | 55.1 |
| 81 |  $KNX | Knight-Swift Transportation Holdings Inc. | $1.6M | 0.4% | -12% | 54.4 |
| 82 |  $BCO | BRINKS CO | $1.6M | 0.3% | NEW | 56.7 |
| 83 |  $ALAB | Astera Labs, Inc. | $1.5M | 0.3% | NEW | 75.1 |
| 84 |  $SPGI | S&P Global Inc. | $1.5M | 0.3% | NEW | 76.1 |
| 85 |  $MDGL | MADRIGAL PHARMACEUTICALS, INC. | $1.5M | 0.3% | +10% | 40.7 |
| 86 |  $EFX | EQUIFAX INC | $1.5M | 0.3% | NEW | 64.8 |
| 87 |  $RYTM | RHYTHM PHARMACEUTICALS, INC. | $1.5M | 0.3% | -19% | 33.9 |
| 88 |  $SVRA | Savara Inc | $1.5M | 0.3% | -3% | — |
| 89 |  $DPZ | DOMINOS PIZZA INC | $1.5M | 0.3% | NEW | 60.1 |
| 90 |  $BLTE | BELITE BIO, INC | $1.5M | 0.3% | +19% | — |
| 91 |  $MU | MICRON TECHNOLOGY INC | $1.5M | 0.3% | -67% | 86.2 |
| 92 |  $CIEN | CIENA CORP | $1.4M | 0.3% | -45% | 72.9 |
| 93 |  $CELC | Celcuity Inc. | $1.4M | 0.3% | +3% | — |
| 94 |  $QXO | QXO, Inc. | $1.4M | 0.3% | +209% | 49 |
| 95 |  $IMCR | Immunocore Holdings plc | $1.4M | 0.3% | -26% | — |
| 96 |  $CGON | CG Oncology, Inc. | $1.3M | 0.3% | -5% | 27 |
| 97 |  $USFD | US Foods Holding Corp. | $1.3M | 0.3% | NEW | 58.4 |
| 98 |  $TDG | TransDigm Group INC | $1.3M | 0.3% | -14% | 68 |
| 99 |  $LITE | Lumentum Holdings Inc. | $1.3M | 0.3% | -51% | 44.3 |
| 100 |  $FE | FIRSTENERGY CORP | $1.2M | 0.3% | NEW | 61.5 |
| 101 |  $MA | Mastercard Inc | $1.2M | 0.3% | -18% | 85.1 |
| 102 |  $ETR | ENTERGY CORP /DE/ | $1.2M | 0.3% | -21% | 59.5 |
| 103 |  $KRYS | Krystal Biotech, Inc. | $1.2M | 0.3% | +79% | 79.2 |
| 104 |  $MCO | MOODYS CORP /DE/ | $1.2M | 0.3% | NEW | 79.1 |
| 105 |  $AMAT | APPLIED MATERIALS INC /DE | $1.2M | 0.3% | NEW | 72.3 |
| 106 |  $XEL | XCEL ENERGY INC | $1.2M | 0.3% | +18% | 56.4 |
| 107 |  $NEE | NEXTERA ENERGY INC | $1.2M | 0.3% | +20% | 64.6 |
| 108 |  $UTHR | UNITED THERAPEUTICS Corp | $1.1M | 0.3% | +38% | 71.3 |
| 109 |  $GLNG | GOLAR LNG LTD | $1.1M | 0.3% | NEW | — |
| 110 |  $DASH | DoorDash, Inc. | $1.1M | 0.2% | -13% | 71 |
| 111 |  $IBN | ICICI BANK LTD | $1.0M | 0.2% | +29% | — |
| 112 |  $IRON | Disc Medicine, Inc. | $1.0M | 0.2% | NEW | — |
| 113 |  $APH | AMPHENOL CORP /DE/ | $1.0M | 0.2% | -41% | 79.3 |
| 114 |  $U | Unity Software Inc. | $1.0M | 0.2% | -44% | 38.9 |
| 115 |  $FERG | Ferguson Enterprises Inc. /DE/ | $990,378 | 0.2% | -11% | 52.2 |
| 116 |  $TRVI | Trevi Therapeutics, Inc. | $989,065 | 0.2% | -1% | — |
| 117 |  $STM | STMicroelectronics N.V. | $988,548 | 0.2% | NEW | — |
| 118 |  $SEPN | Septerna, Inc. | $982,496 | 0.2% | NEW | 59.2 |
| 119 |  $YMM | Full Truck Alliance Co. Ltd. | $981,278 | 0.2% | +57% | — |
| 120 |  $BBIO | BridgeBio Pharma, Inc. | $979,859 | 0.2% | -73% | 36.9 |
| 121 |  $ARM | ARM HOLDINGS PLC /UK | $957,339 | 0.2% | NEW | — |
| 122 |  $TPR | TAPESTRY, INC. | $951,470 | 0.2% | NEW | 72.7 |
| 123 |  $EDU | New Oriental Education & Technology Group Inc. | $942,853 | 0.2% | +67% | — |
| 124 |  $SIMO | Silicon Motion Technology CORP | $933,324 | 0.2% | NEW | — |
| 125 |  $APG | APi Group Corp | $929,921 | 0.2% | -18% | 65.4 |
| 126 |  $URGN | UroGen Pharma Ltd. | $918,822 | 0.2% | -6% | — |
| 127 |  $MSFT | MICROSOFT CORP | $900,097 | 0.2% | -63% | 79.8 |
| 128 |  $ZYME | Zymeworks Inc. | $889,100 | 0.2% | -0% | 8.7 |
| 129 |  $AEIS | ADVANCED ENERGY INDUSTRIES INC | $835,229 | 0.2% | NEW | 61.7 |
| 130 |  $KSPI | Joint Stock Co Kaspi.kz | $814,416 | 0.2% | NEW | — |
| 131 |  $HDB | HDFC BANK LTD | $798,845 | 0.2% | +18% | — |
| 132 |  $VST | Vistra Corp. | $777,287 | 0.2% | NEW | 71.9 |
| 133 |  $JANX | Janux Therapeutics, Inc. | $743,056 | 0.2% | -2% | 30.1 |
| 134 |  $NAMS | NewAmsterdam Pharma Co N.V. | $708,470 | 0.2% | +4% | — |
| 135 |  $META | Meta Platforms, Inc. | $654,543 | 0.1% | -33% | 79.6 |
| 136 |  $MBX | MBX Biosciences, Inc. | $642,197 | 0.1% | +1% | — |
| 137 |  $NU | Nu Holdings Ltd. | $640,879 | 0.1% | -3% | — |
| 138 |  $CTMX | CytomX Therapeutics, Inc. | $636,866 | 0.1% | -41% | 8.7 |
| 139 |  $MELI | MERCADOLIBRE INC | $636,521 | 0.1% | -14% | 80.2 |
| 140 |  $CEG | Constellation Energy Corp | $618,442 | 0.1% | -57% | 59.4 |
| 141 |  $NKTR | NEKTAR THERAPEUTICS | $607,906 | 0.1% | -40% | 9.7 |
| 142 |  $AKAM | AKAMAI TECHNOLOGIES INC | $579,229 | 0.1% | NEW | 59.5 |
| 143 |  $XNCR | Xencor Inc | $431,834 | 0.1% | -49% | 11.6 |
| 144 |  $KYMR | Kymera Therapeutics, Inc. | $427,834 | 0.1% | -1% | 28.4 |
| 145 |  $PDD | PDD Holdings Inc. | $419,540 | 0.1% | -20% | — |
| 146 |  $JD | JD.com, Inc. | $360,873 | 0.1% | +5% | — |
| 147 |  $SOBO | South Bow Corp | $357,868 | 0.1% | -50% | — |
New Positions (29)
$CCCC C4 Therapeutics, Inc.$6.3M$RLMD RELMADA THERAPEUTICS, INC.$3.1M$TXN TEXAS INSTRUMENTS INC$1.9M$DNOW DNOW Inc.$1.7M$NUE NUCOR CORP$1.7M$TDAY USA TODAY Co., Inc.$1.6M$CLMT Calumet, Inc. /DE$1.6M$Q Qnity Electronics, Inc.$1.6M$CRDO Credo Technology Group Holding Ltd$1.6M$BCO BRINKS CO$1.6M$ALAB Astera Labs, Inc.$1.5M$SPGI S&P Global Inc.$1.5M$EFX EQUIFAX INC$1.5M$DPZ DOMINOS PIZZA INC$1.5M$USFD US Foods Holding Corp.$1.3MExited Positions (38)
$TERN Terns Pharmaceuticals, Inc.
$NUVL Nuvalent, Inc.
$SLNO SOLENO THERAPEUTICS INC
$APGE Apogee Therapeutics, Inc.
$JAZZ Jazz Pharmaceuticals plc
$NATL NCR Atleos Corp
$CLH CLEAN HARBORS INC
$CRM Salesforce, Inc.
$XOMA XOMA Royalty Corp
$AVTR Avantor, Inc.
$ASND Ascendis Pharma A/S
$INTU INTUIT INC.
$BKNG Booking Holdings Inc.
$KRC KILROY REALTY CORP
$EQT EQT CorpBrowse Top Institutional Investors
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