UNITED THERAPEUTICS Corp(UTHR)Stock Analysis
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Rank #46 of 2,879 stocksTOP 5%
Rankings refresh quarterly once 80% of peers have filed (~45 days after quarter-end). Next update: ~Aug 14, 2026.
Revenue Growth
Profitability
Balance Sheet
Earnings Quality
Free Cash Flow
Institutional Flow
Revenue Scale
Dilution Risk
UTHR Stock Analysis & AI Quality Score
AI stock analysis and institutional research for UNITED THERAPEUTICS Corp (UTHR), a Healthcare sector company. 13F Pro's AI-powered ranking engine scores UTHR at 80.1/100 on a 32-signal composite quality model, placing it at rank #46 of 2,879 stocks — the top 5% of the AI-ranked universe. UTHR scores in the top quartile across balance sheet strength (93.8), profitability (92.5), institutional flow (91.2). Shareholder dilution risk is elevated at 27.0/100, reflecting ongoing share issuance or stock-based compensation. Based on the latest XBRL financial filings (Q1 2026), UNITED THERAPEUTICS Corp reports quarterly revenue of $781.5M, net income of $274.9M, an operating margin of 41.7%. Top institutional holders of UTHR by reported 13-F value include BlackRock,, Avoro Capital Advisors, WELLINGTON MANAGEMENT GROUP LLP, based on the most recent SEC filings. UTHR trades on the Nasdaq exchange and files with the SEC under CIK 1082554. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate UTHR daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for UNITED THERAPEUTICS Corp directly from SEC EDGAR. UNITED THERAPEUTICS Corp's 13F Pro composite quality score has ranged between 8 and 86 since 2021, currently 80.1 — an improving long-term trajectory across 56 quarterly and live scoring snapshots.
What's Driving UTHR's Business? Latest 10-Q Breakdown
AI-extracted from UNITED THERAPEUTICS Corp's 10-Q filed 2026-05-06 — Q1 2026 (quarter ended March 31, 2026). Every figure is machine-verified against the filing text on SEC EDGAR.
United Therapeutics reported Q1 2026 revenues of $781.5M, down 2% YoY, with Tyvaso DPI growth (+9%) offset by Nebulized Tyvaso decline (-22%), while executing $1.5B share repurchase and advancing pipeline programs including successful ADVANCE OUTCOMES and TETON trials.
Biggest Revenue Drivers
Total revenue: $781.5M-2% YoY
Increase in quantities sold of $16.0M, plus modest price increase
Increase in quantities sold of $10.2M
Decrease in U.S. quantities sold of $33.3M and international decline, partially offset by price increase
Decrease in quantities sold of $11.1M
Largest Expense Items
General and administrative costs up 7%; share-based compensation up 15%
Decrease in milestone payments for drug delivery devices, offset by increased personnel expenses
Watch Items from the Filing
- Two distributors account for 87% of total revenues (52% and 35%), creating concentration risk. Distributor ordering patterns can cause revenue volatility unrelated to patient demand.
- Nebulized Tyvaso revenues declined 22% YoY; pending FDA approval for IPF indication expected by summer 2026, but DME MACs must update local coverage determination, a process potentially exceeding one year.
- Tyvaso DPI inventory reserve increased $39.2M in Q1 2026 due to $26.8M loss on commercial supply agreement; supply management risk could impact future cost of sales.
- Sandoz litigation: $74.9M accrued liability through March 31, 2026; appeal pending before Third Circuit Court; unfavorable appellate outcome could increase exposure materially.
- Successful ADVANCE OUTCOMES trial (ralinepag): 55% reduction in clinical worsening risk; NDA submission targeted summer 2026; positions ralinepag favorably vs. Uptravi ($1.9B global sales in 2025).
AI-extracted and verified against SEC EDGAR filing text. Not investment advice.
Revenue
Q1 2026
$781.5M
Net Income
Q1 2026
$274.9M
Free Cash Flow
Q1 2026
$362.5M
Operating Margin
Q1 2026
41.7%
Revenue & Net Income
Earnings Per Share
Key Financials Over Time
Export Financial Table · Pro+Revenue
+36.7% YoYNet Income
+35.5% YoYOperating Income
+26.0% YoYEPS (Diluted)
+40.6% YoYTotal Assets
+9.9% YoYOp. Cash Flow
+59.6% YoY| Metric | FY 2025 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|
| Revenue | $3.18B +36.7% | $2.33B +20.2% | $1.94B +14.9% | $1.69B +13.6% | $1.48B +2.4% | $1.45B |
| Net Income | $1.33B +35.5% | $984.8M +35.4% | $727.3M +52.9% | $475.8M | — | — |
| Operating Income | $1.49B +26.0% | $1.18B +20.9% | $979.7M +76.2% | $555.9M -6.4% | $593.6M +416.4% | $-187.6M |
| EPS (Diluted) | $27.86 +40.6% | $19.81 +32.1% | $15.00 +49.1% | $10.06 -12.8% | $11.54 +582.8% | $-2.39 |
| Total Assets | $7.88B +9.9% | $7.17B +18.6% | $6.04B +16.9% | $5.17B +12.0% | $4.62B +17.9% | $3.91B |
| Operating Cash Flow | $1.56B +59.6% | $978.0M +21.9% | $802.5M +34.2% | $598.2M -20.8% | $755.7M +465.8% | $-206.6M |
AI Insight: UTHR Ratio Trends
Operating margin compressed to 41.7% in Q1 2026, down 7.4pp from Q4 2025, signaling near-term profitability pressure despite sustained high net margins.
• Net profit margin spiked to 46.1% in Q4 2025 then fell to 35.2% in Q1 2026, a 10.9pp decline—largest quarterly swing in dataset.
• ROIC compressed from 23.6% in Q3 2025 to 20.1% in Q4 2025, then recovered slightly to 22.1% in Q1 2026, showing volatility.
• ROE fell from 20.6% in Q3 2025 to 18.6% in Q1 2026, a 2pp decline marking weakness in shareholder returns generation.
⚠ Q1 2026 operating margin at 41.7% is lowest in nine-quarter dataset; trend continuation would signal structural margin erosion.
⚠ ROA declined to 16.4% in Q1 2026 from 18.5% in Q4 2025—monitor if asset productivity deterioration persists.
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Top Institutional Holders of UTHR
BlackRock, Inc.
$3.2B5,399,649 shAvoro Capital Advisors LLC
$1.6B2,630,000 shWELLINGTON MANAGEMENT GROUP LLP
$1.3B2,264,247 shVANGUARD PORTFOLIO MANAGEMENT LLC
$1.2B2,003,742 shVANGUARD CAPITAL MANAGEMENT LLC
$1.2B1,957,539 shSTATE STREET CORP
$1.1B1,843,963 shRENAISSANCE TECHNOLOGIES LLC
$1.1B1,787,019 shGEODE CAPITAL MANAGEMENT, LLC
$729.9M1,233,029 shJANUS HENDERSON GROUP PLC
$514.0M866,930 shAQR CAPITAL MANAGEMENT LLC
$486.4M826,226 sh
| Fund | Value | Shares |
|---|---|---|
| BlackRock, Inc. | $3.2B | 5,399,649 |
| Avoro Capital Advisors LLC | $1.6B | 2,630,000 |
| WELLINGTON MANAGEMENT GROUP LLP | $1.3B | 2,264,247 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1.2B | 2,003,742 |
| VANGUARD CAPITAL MANAGEMENT LLC | $1.2B | 1,957,539 |
| STATE STREET CORP | $1.1B | 1,843,963 |
| RENAISSANCE TECHNOLOGIES LLC | $1.1B | 1,787,019 |
| GEODE CAPITAL MANAGEMENT, LLC | $729.9M | 1,233,029 |
| JANUS HENDERSON GROUP PLC | $514.0M | 866,930 |
| AQR CAPITAL MANAGEMENT LLC | $486.4M | 826,226 |
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Is UTHR a good stock to buy?
13F Pro's AI-powered analysis of UNITED THERAPEUTICS Corp (UTHR) draws on SEC EDGAR-sourced fundamentals, institutional 13F holdings, and insider Form 4 transactions in the Healthcare sector (listed on Nasdaq). The 32-signal AI Quality Score, current rank, and full bull/bear verdict for UTHR are available on the UTHR stock profile dashboard — with the same data, AI insights, ratios, and institutional activity refreshed after every 10-K, 10-Q, 13F, and Form 4 filing.
Which hedge funds own UTHR?
Institutional investors are required to disclose their holdings quarterly via SEC Form 13F. 13F Pro aggregates these filings to show which hedge funds, mutual funds, and asset managers are buying or selling UTHR. Combined with insider transaction data from Form 4 filings and AI-powered analysis from 10 specialized research agents, 13F Pro provides a comprehensive view of UNITED THERAPEUTICS Corp's investment landscape.