NEUROCRINE BIOSCIENCES INC(NBIX)Stock Analysis
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Rank #128 of 2,879 stocksTOP 5%
Rankings refresh quarterly once 80% of peers have filed (~45 days after quarter-end). Next update: ~Aug 14, 2026.
Revenue Growth
Profitability
Balance Sheet
Earnings Quality
Free Cash Flow
Institutional Flow
Revenue Scale
Dilution Risk
NBIX Stock Analysis & AI Quality Score
AI stock analysis and institutional research for NEUROCRINE BIOSCIENCES INC (NBIX), a Healthcare sector company. 13F Pro's AI-powered ranking engine scores NBIX at 75.4/100 on a 32-signal composite quality model, placing it at rank #128 of 2,879 stocks — the top 5% of the AI-ranked universe. NBIX scores in the top quartile across earnings quality (91.7), balance sheet strength (88.7), profitability (85.2). Areas of concern include institutional flow (22.3), which score below median versus the broader universe. Shareholder dilution risk is elevated at 20.3/100, reflecting ongoing share issuance or stock-based compensation. Based on the latest XBRL financial filings (Q1 2026), NEUROCRINE BIOSCIENCES INC reports quarterly revenue of $814.5M, net income of $197.9M, an operating margin of 23.7%. Top institutional holders of NBIX by reported 13-F value include BlackRock,, DODGE & COX, AQR CAPITAL MANAGEMENT, based on the most recent SEC filings. NBIX trades on the Nasdaq exchange and files with the SEC under CIK 914475. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate NBIX daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for NEUROCRINE BIOSCIENCES INC directly from SEC EDGAR. NEUROCRINE BIOSCIENCES INC's 13F Pro composite quality score has ranged between 8 and 89 since 2021, currently 75.4 — a declining long-term trajectory across 56 quarterly and live scoring snapshots.
What's Driving NBIX's Business? Latest 10-Q Breakdown
AI-extracted from NEUROCRINE BIOSCIENCES INC's 10-Q filed 2026-05-05 — Q1 2026 (quarter ended March 31, 2026). Every figure is machine-verified against the filing text on SEC EDGAR.
Biggest Revenue Drivers
Driven primarily by volume growth and record new prescriptions on strong patient demand.
First-in-class treatment for CAH launched in U.S. December 2024; reflects full quarter of commercial sales in Q1 2026.
Primarily royalties on AbbVie net sales of elagolix and Tanabe Pharma net sales of valbenazine.
Largest Expense Items
Increased royalties payable on net product sales of CRENESSITY and increased total net product sales.
Increased payments for upfront fees in connection with collaborations, including $22.5M milestone to Nxera for NBI-1117570 Phase 2 initiation.
Watch Items from the Filing
- Pending acquisition of Soleno Therapeutics for ~$2.9B in cash (commenced April 20, 2026); HSR waiting period expired April 27, 2026; transaction expected to close Q2 2026 but dependent on majority tender and closing conditions; would significantly reduce cash and investment balances.
- DOJ civil investigative demand received August 2025 regarding INGREZZA sales and marketing practices; investigation timing and outcome uncertain, creating legal risk and potential regulatory exposure.
- INGREZZA qualifies for small biotech exception from Medicare Drug Negotiation Program until 2027; if selected in 2029, negotiated pricing would apply, constrained by 'short monopoly' price ceiling; loss of exemption could materially impact revenues and formulary coverage.
- Completed sale of Neurocrine Group Limited on January 21, 2026 for $63.2M cash, recognizing $28.6M pre-tax gain; divestiture reduces diversification but provides liquidity for Soleno acquisition.
AI-extracted and verified against SEC EDGAR filing text. Not investment advice.
Revenue
Q1 2026
$814.5M
Net Income
Q1 2026
$197.9M
Free Cash Flow
Q1 2026
$136.7M
Operating Margin
Q1 2026
23.7%
Revenue & Net Income
Earnings Per Share
Key Financials Over Time
Export Financial Table · Pro+Revenue
+21.4% YoYNet Income
+40.2% YoYOperating Income
+8.5% YoYEPS (Diluted)
+41.9% YoYTotal Assets
+24.5% YoYOp. Cash Flow
+31.5% YoY| Metric | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| Revenue | $2.86B +21.4% | $2.36B +24.8% | $1.89B +26.8% | $1.49B +31.3% | $1.13B +8.4% | $1.05B |
| Net Income | $478.6M +40.2% | $341.3M +36.7% | $249.7M +61.6% | $154.5M +72.4% | $89.6M -78.0% | $407.3M |
| Operating Income | $619.1M +8.5% | $570.5M +127.4% | $250.9M +0.8% | $249.0M +142.9% | $102.5M -37.1% | $163.0M |
| EPS (Diluted) | $4.67 +41.9% | $3.29 +33.2% | $2.47 +58.3% | $1.56 +69.6% | $0.92 -77.9% | $4.16 |
| Total Assets | $4.63B +24.5% | $3.72B +14.4% | $3.25B +37.3% | $2.37B +14.3% | $2.07B +19.5% | $1.73B |
| Operating Cash Flow | $782.7M +31.5% | $595.4M +52.7% | $389.9M +14.9% | $339.4M +32.3% | $256.5M +12.3% | $228.5M |
AI Insight: NBIX Financial Trends
NBIX delivered its highest-ever quarterly revenue of $814M in Q1 2026, while net income surged to $198M — the strongest Q1 profit in the dataset.
• Revenue grew 38% year-over-year from $590M in Q2 2024 to $814M in Q1 2026, with consistent sequential gains since Q1 2025.
• Net income expanded dramatically from $8M in Q1 2025 to $198M in Q1 2026, a ~24x year-over-year improvement.
• Equity strengthened from $2,509M in Q2 2024 to $3,407M in Q1 2026, reflecting six quarters of cumulative earnings retention.
• Operating cash flow hit $388M in Q4 2025 before normalizing to $146M in Q1 2026, consistent with typical seasonal Q1 patterns.
⚠ Q1 operating income of $193M lagged Q4 2025's $211M despite higher revenue — operating margin compression warrants monitoring.
⚠ Total debt data is absent across all periods; leverage position and interest burden remain unassessable.
⚠ Q1 2025 net income collapsed to $8M — recurring seasonal cost spikes could cap annual earnings if not managed.
AI Insight: NBIX Ratio Trends
Q3 2025 peak margins and ROIC of 31.8% confirm a strong underlying business, but Q1 profitability remains structurally weak — a recurring seasonal pattern to watch.
• ROIC peaked at 31.8% in Q3 2025, up from 21.9% in Q4 2024, signaling strong capital efficiency at mid-year.
• Net profit margin surged to 26.4% in Q3 2025 and held at 24.3% in Q1 2026, well above Q2 2024's 11.0%.
• Q1 2025 operating margin collapsed to 4.1% and ROIC to 3.7%, mirroring a sharp seasonal or one-off earnings trough.
⚠ Q1 profitability troughs repeatedly — Q1 2026 OpMargin of 23.7% vs. Q3 2025's 30.1% warrants scrutiny for recurring cost spikes.
⚠ D/E data is entirely absent; leverage profile cannot be assessed, leaving balance sheet risk unquantified.
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Top Institutional Holders of NBIX
BlackRock, Inc.
$1.8B13,385,607 shDODGE & COX
$719.4M5,461,037 shAQR CAPITAL MANAGEMENT LLC
$650.7M4,938,967 shVANGUARD PORTFOLIO MANAGEMENT LLC
$622.6M4,726,344 shVANGUARD CAPITAL MANAGEMENT LLC
$594.4M4,511,904 shSTATE STREET CORP
$573.7M4,354,526 shTWO SIGMA INVESTMENTS, LP
$403.2M3,060,570 shRENAISSANCE TECHNOLOGIES LLC
$318.7M2,418,897 shGEODE CAPITAL MANAGEMENT, LLC
$280.8M2,136,672 shBNP Paribas Asset Management Holding S.A.
$196.8M1,493,813 sh
| Fund | Value | Shares |
|---|---|---|
| BlackRock, Inc. | $1.8B | 13,385,607 |
| DODGE & COX | $719.4M | 5,461,037 |
| AQR CAPITAL MANAGEMENT LLC | $650.7M | 4,938,967 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $622.6M | 4,726,344 |
| VANGUARD CAPITAL MANAGEMENT LLC | $594.4M | 4,511,904 |
| STATE STREET CORP | $573.7M | 4,354,526 |
| TWO SIGMA INVESTMENTS, LP | $403.2M | 3,060,570 |
| RENAISSANCE TECHNOLOGIES LLC | $318.7M | 2,418,897 |
| GEODE CAPITAL MANAGEMENT, LLC | $280.8M | 2,136,672 |
| BNP Paribas Asset Management Holding S.A. | $196.8M | 1,493,813 |
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Is NBIX a good stock to buy?
13F Pro's AI-powered analysis of NEUROCRINE BIOSCIENCES INC (NBIX) draws on SEC EDGAR-sourced fundamentals, institutional 13F holdings, and insider Form 4 transactions in the Healthcare sector (listed on Nasdaq). The 32-signal AI Quality Score, current rank, and full bull/bear verdict for NBIX are available on the NBIX stock profile dashboard — with the same data, AI insights, ratios, and institutional activity refreshed after every 10-K, 10-Q, 13F, and Form 4 filing.
Which hedge funds own NBIX?
Institutional investors are required to disclose their holdings quarterly via SEC Form 13F. 13F Pro aggregates these filings to show which hedge funds, mutual funds, and asset managers are buying or selling NBIX. Combined with insider transaction data from Form 4 filings and AI-powered analysis from 10 specialized research agents, 13F Pro provides a comprehensive view of NEUROCRINE BIOSCIENCES INC's investment landscape.