VERTEX PHARMACEUTICALS INC / MA (VRTX) — Institutional Holders, Q2 2026 (page 5)
1,768 institutional investment managers reported a VRTX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $119.6B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 401 to 500. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
VRTX 13F holders ranked 401–500 of 1,768
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 401 | Baldwin Investment Management#401 · 16,870 sh | 16,870 | $8.4M | 0.81% | +7.7% |
| 402 | Trifecta Capital Advisors#402 · 16,745 sh | 16,745 | $8.3M | — | -0.1% |
| 403 | Sequoia Financial Advisors#403 · 16,729 sh | 16,729 | $8.3M | 0.04% | +12.3% |
| 404 | HANTZ FINANCIAL SERVICES#404 · 16,664 sh | 16,664 | $8.3M | 0.11% | -6.4% |
| 405 | SOMERVILLE KURT F#405 · 16,441 sh | 16,441 | $8.2M | 1.95% | -1.8% |
| 406 | Hamilton Capital Partners#406 · 16,419 sh | 16,419 | $8.2M | 0.24% | +16.8% |
| 407 | SILVERCREST ASSET MANAGEMENT GROUP#407 · 16,346 sh | 16,346 | $8.1M | 0.05% | -0.1% |
| 408 | Investment Management of Ontario#408 · 16,215 sh | 16,215 | $8.1M | 0.10% | -17.1% |
| 409 | Kentucky Retirement Systems#409 · 16,023 sh | 16,023 | $8.0M | 0.20% | -17.0% |
| 410 | Fulcrum Capital#410 · 15,958 sh | 15,958 | $7.9M | — | -3.3% |
| 411 | PUZO MICHAEL J#411 · 15,907 sh | 15,907 | $7.9M | 2.04% | +3.2% |
| 412 | Callan Family Office#412 · 15,789 sh | 15,789 | $7.8M | 0.15% | +3.5% |
| 413 | ANDERSON HOAGLAND#413 · 15,734 sh | 15,734 | $7.8M | — | 0.0% |
| 414 | Kestra Advisory Services#414 · 15,732 sh | 15,732 | $7.8M | 0.03% | +12.8% |
| 415 | LEUTHOLD GROUP#415 · 15,640 sh | 15,640 | $7.8M | 0.78% | -5.0% |
| 416 | LBP AM SA#416 · 15,597 sh | 15,597 | $7.7M | 0.08% | -84.2% |
| 417 | EXCHANGE TRADED CONCEPTS#417 · 15,357 sh | 15,357 | $7.6M | 0.03% | +10.7% |
| 418 | TORRAY#418 · 15,215 sh | 15,215 | $7.6M | 1.02% | -1.1% |
| 419 | Generali Asset Management SPA SGR#419 · 15,161 sh | 15,161 | $7.5M | — | -0.9% |
| 420 | ARDSLEY ADVISORY PARTNERS#420 · 15,000 sh | 15,000 | $7.5M | 0.78% | New |
| 421 | NIA IMPACT ADVISORS#421 · 14,663 sh | 14,663 | $7.3M | 3.02% | -5.3% |
| 422 | Kidder Stephen W#422 · 14,603 sh | 14,603 | $7.3M | 1.83% | +14.8% |
| 423 | Knuff#423 · 14,288 sh | 14,288 | $7.1M | 1.80% | +2.2% |
| 424 | Union Bankshares#424 · 14,182 sh | 14,182 | $7.0M | 0.12% | -2.2% |
| 425 | Dai-ichi Life Insurance Company, Ltd#425 · 14,165 sh | 14,165 | $7.0M | 0.16% | 0.0% |
| 426 | PRINCETON CAPITAL MANAGEMENT#426 · 14,074 sh | 14,074 | $7.0M | — | -3.1% |
| 427 | HARTFORD INVESTMENT MANAGEMENT#427 · 14,038 sh | 14,038 | $7.0M | 0.20% | -3.1% |
| 428 | M&T BANK#428 · 13,959 sh | 13,959 | $6.9M | 0.02% | +6.7% |
| 429 | Aptus Capital Advisors#429 · 13,787 sh | 13,787 | $6.8M | 0.05% | -5.9% |
| 430 | TD Waterhouse Canada#430 · 13,646 sh | 13,646 | $6.8M | — | -0.9% |
| 431 | Maryland State Retirement & Pension System#431 · 13,627 sh | 13,627 | $6.8M | 0.12% | +6.1% |
| 432 | Slow Capital#432 · 13,274 sh | 13,274 | $6.6M | — | +7.9% |
| 433 | Princeton Global Asset Management#433 · 13,233 sh | 13,233 | $6.6M | — | -0.2% |
| 434 | Andrew Hill Investment Advisors#434 · 13,232 sh | 13,232 | $6.6M | — | +10.7% |
| 435 | NLB Skladi, upravljanje premozenja, d.o.o.#435 · 13,181 sh | 13,181 | $6.5M | — | -19.1% |
| 436 | Compagnie Lombard Odier SCmA#436 · 13,065 sh | 13,065 | $6.5M | 0.07% | -0.1% |
| 437 | CAISSE DE DEPOT ET PLACEMENT DU QUEBEC#437 · 13,042 sh | 13,042 | $6.5M | <0.01% | -74.4% |
| 438 | Fisher Funds Management LTD#438 · 12,898 sh | 12,898 | $6.4M | — | 0.0% |
| 439 | Meiji Yasuda Asset Management Ltd.#439 · 12,740 sh | 12,740 | $6.3M | 0.28% | +42.5% |
| 440 | GLENMEDE NA#440 · 12,722 sh | 12,722 | $6.3M | 0.03% | +126.9% |
| 441 | NEW MEXICO EDUCATIONAL RETIREMENT BOARD#441 · 12,700 sh | 12,700 | $6.3M | 0.16% | +8.5% |
| 442 | KAYNE ANDERSON RUDNICK INVESTMENT MANAGEMENT#442 · 12,660 sh | 12,660 | $6.3M | 0.02% | -3.2% |
| 443 | Vident Advisory#443 · 12,522 sh | 12,522 | $6.2M | 0.04% | -22.0% |
| 444 | UNITED CAPITAL FINANCIAL ADVISORS#444 · 12,438 sh | 12,438 | $6.2M | 0.03% | +1.7% |
| 445 | Ameritas Investment Partners#445 · 12,422 sh | 12,422 | $6.2M | 0.16% | -1.1% |
| 446 | Holocene Advisors#446 · 12,384 sh | 12,384 | $6.2M | 0.01% | -81.7% |
| 447 | J. Goldman#447 · 12,311 sh | 12,311 | $6.1M | 0.16% | New |
| 448 | Merit Financial Group#448 · 12,218 sh | 12,218 | $6.1M | 0.04% | +18.2% |
| 449 | Squarepoint Ops#449 · 12,031 sh | 12,031 | $6.0M | <0.01% | +78.2% |
| 450 | GREENWOOD CAPITAL ASSOCIATES#450 · 12,024 sh | 12,024 | $6.0M | — | -0.6% |
| 451 | Siemens Fonds Invest GmbH#451 · 11,930 sh | 11,930 | $5.9M | 0.29% | +2.2% |
| 452 | Orion Porfolio Solutions#452 · 11,853 sh | 11,853 | $5.9M | 0.05% | -0.1% |
| 453 | Covenant Asset Management#453 · 11,782 sh | 11,782 | $5.9M | — | -2.5% |
| 454 | Baader Bank Aktiengesellschaft#454 · 11,777 sh | 11,777 | $5.8M | 0.44% | +123.0% |
| 455 | Delaney Dennis R#455 · 11,733 sh | 11,733 | $5.8M | 1.86% | +0.7% |
| 456 | Laird Norton Wetherby Company#456 · 11,528 sh | 11,528 | $5.7M | 0.11% | -3.0% |
| 457 | DCF Advisers#457 · 11,500 sh | 11,500 | $5.7M | 1.01% | +64.3% |
| 458 | HOWE & RUSLING#458 · 11,499 sh | 11,499 | $5.7M | 0.33% | +18.3% |
| 459 | E Fund Management , Ltd.#459 · 11,455 sh | 11,455 | $5.7M | 0.13% | +5.9% |
| 460 | AG2R LA MONDIALE GESTION D'ACTIFS#460 · 11,324 sh | 11,324 | $5.6M | — | +9.1% |
| 461 | NewEdge Wealth#461 · 11,305 sh | 11,305 | $5.6M | 0.06% | +15.5% |
| 462 | JANE STREET GROUP#462 · 11,231 sh | 11,231 | $5.6M | <0.01% | -90.9% |
| 463 | FIRST HORIZON NATIONAL#463 · 11,201 sh | 11,201 | $5.6M | — | -22.9% |
| 464 | Jones Hill Capital#464 · 11,123 sh | 11,123 | $5.5M | 1.17% | -89.8% |
| 465 | HB Wealth Management#465 · 11,065 sh | 11,065 | $5.5M | — | +7.6% |
| 466 | PKO Investment Management Joint-Stock#466 · 11,050 sh | 11,050 | $5.5M | — | +0.5% |
| 467 | BENJAMIN EDWARDS#467 · 11,025 sh | 11,025 | $5.5M | 0.05% | -0.8% |
| 468 | Metis Global Partners#468 · 10,929 sh | 10,929 | $5.4M | 0.12% | -6.3% |
| 469 | New Age Alpha Advisors#469 · 10,927 sh | 10,927 | $5.4M | 0.23% | -4.3% |
| 470 | Bridgewater Associates#470 · 10,865 sh | 10,865 | $5.4M | 0.02% | -18.7% |
| 471 | Joseph Group Capital Management#471 · 10,756 sh | 10,756 | $5.3M | 1.12% | +2.3% |
| 472 | Northwest Bancshares#472 · 10,706 sh | 10,706 | $5.3M | 0.96% | +2.8% |
| 473 | Generali Investments CEE, investicni spolecnost, a.s.#473 · 10,599 sh | 10,599 | $5.3M | — | 0.0% |
| 474 | KESTRA PRIVATE WEALTH SERVICES#474 · 10,539 sh | 10,539 | $5.2M | 0.06% | +8.9% |
| 475 | Morse Asset Management#475 · 10,526 sh | 10,526 | $5.2M | 0.87% | -0.4% |
| 476 | Simplify Asset Management#476 · 10,456 sh | 10,456 | $5.2M | — | +31.8% |
| 477 | BESSEMER GROUP#477 · 10,408 sh | 10,408 | $5.2M | <0.01% | +21.5% |
| 478 | GAM Holding AG#478 · 10,376 sh | 10,376 | $5.2M | 0.39% | +85.9% |
| 479 | Miracle Mile Advisors#479 · 10,324 sh | 10,324 | $5.1M | 0.06% | +8.5% |
| 480 | PARK AVENUE SECURITIES#480 · 10,198 sh | 10,198 | $5.1M | — | -14.4% |
| 481 | ODDO BHF ASSET MANAGEMENT SAS#481 · 10,151 sh | 10,151 | $5.0M | 0.23% | 0.0% |
| 482 | Concurrent Investment Advisors#482 · 10,145 sh | 10,145 | $5.0M | — | +7.0% |
| 483 | NWAM#483 · 10,129 sh | 10,129 | $5.0M | 0.25% | +60.0% |
| 484 | LEVEL FOUR ADVISORY SERVICES#484 · 10,034 sh | 10,034 | $5.0M | 0.14% | +5.4% |
| 485 | Banque Cantonale Vaudoise#485 · 10,020 sh | 10,020 | $5.0M | 0.19% | +12.2% |
| 486 | FAYEZ SAROFIM#486 · 10,000 sh | 10,000 | $5.0M | 0.01% | 0.0% |
| 487 | LMR Partners LLP#487 · 9,962 sh | 9,962 | $4.9M | 0.02% | -49.8% |
| 488 | KEYBANK NATIONAL ASSOCIATION#488 · 9,934 sh | 9,934 | $4.9M | 0.02% | -4.5% |
| 489 | TOKIO MARINE ASSET MANAGEMENT LTD#489 · 9,895 sh | 9,895 | $4.9M | — | +5.0% |
| 490 | PARSONS CAPITAL MANAGEMENT#490 · 9,779 sh | 9,779 | $4.9M | 0.22% | +1.4% |
| 491 | NORTHWESTERN MUTUAL WEALTH MANAGEMENT#491 · 9,613 sh | 9,613 | $4.8M | <0.01% | +8.5% |
| 492 | Jain Global#492 · 9,529 sh | 9,529 | $4.7M | 0.02% | +103.7% |
| 493 | Caption Management#493 · 9,400 sh | 9,400 | $4.7M | 0.02% | +4600.0% |
| 494 | Privium Fund Management B.V.#494 · 9,400 sh | 9,400 | $4.7M | 0.86% | -17.2% |
| 495 | MARK SHEPTOFF FINANCIAL PLANNING#495 · 9,295 sh | 9,295 | $4.6M | 2.45% | -2.6% |
| 496 | Elefante Mark B#496 · 9,285 sh | 9,285 | $4.6M | 1.99% | +14.1% |
| 497 | Peloton Wealth Strategists#497 · 9,280 sh | 9,280 | $4.6M | 1.70% | +1.5% |
| 498 | OFI INVEST ASSET MANAGEMENT#498 · 10,449 sh | 10,449 | $4.5M | 0.05% | -84.9% |
| 499 | LITTLE HOUSE CAPITAL#499 · 9,134 sh | 9,134 | $4.5M | 1.02% | +1.9% |
| 500 | SIGMA INVESTMENT COUNSELORS#500 · 9,089 sh | 9,089 | $4.5M | — | -5.5% |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.