VERTEX PHARMACEUTICALS INC / MA (VRTX) — Institutional Holders, Q2 2026 (page 2)
1,768 institutional investment managers reported a VRTX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $119.6B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 101 to 200. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
VRTX 13F holders ranked 101–200 of 1,768
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 101 | WELCH & FORBES#101 · 221,304 sh | 221,304 | $109.9M | 1.34% | +0.7% |
| 102 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM#102 · 219,813 sh | 219,813 | $109.2M | 0.18% | -2.2% |
| 103 | Handelsbanken Fonder AB#103 · 218,292 sh | 218,292 | $108.4M | 0.31% | -1.2% |
| 104 | Korea Investment#104 · 213,312 sh | 213,312 | $106.0M | 0.20% | +6.0% |
| 105 | JONES FINANCIAL COMPANIES LLLP#105 · 215,419 sh | 215,419 | $105.8M | 0.04% | +6.2% |
| 106 | Capital International Sarl#106 · 210,718 sh | 210,718 | $104.7M | 1.48% | +0.9% |
| 107 | abrdn plc#107 · 210,601 sh | 210,601 | $104.6M | 0.15% | -9.8% |
| 108 | Ensign Peak Advisors#108 · 210,483 sh | 210,483 | $104.6M | 0.17% | -2.2% |
| 109 | Mirae Asset Global Investments , Ltd.#109 · 210,209 sh | 210,209 | $104.4M | 0.15% | +11.8% |
| 110 | AGF MANAGEMENT LTD#110 · 207,971 sh | 207,971 | $103.3M | 0.40% | +3.3% |
| 111 | TD ASSET MANAGEMENT#111 · 207,960 sh | 207,960 | $103.3M | 0.09% | -8.9% |
| 112 | DAVENPORT#112 · 207,108 sh | 207,108 | $103.0M | — | -1.4% |
| 113 | NEW YORK STATE TEACHERS RETIREMENT SYSTEM#113 · 206,935 sh | 206,935 | $102.8M | — | -2.1% |
| 114 | APG Asset Management N.V.#114 · 234,624 sh | 234,624 | $101.9M | 0.25% | +22.6% |
| 115 | Tri Locum Partners#115 · 201,791 sh | 201,791 | $100.2M | 12.33% | +56.0% |
| 116 | Candriam S.C.A.#116 · 199,505 sh | 199,505 | $99.0M | 0.45% | -12.8% |
| 117 | NEOS Investment Management#117 · 193,306 sh | 193,306 | $96.0M | 0.35% | +11.0% |
| 118 | GROUPAMA ASSET MANAGMENT#118 · 188,156 sh | 188,156 | $93.9M | 1.18% | +13.4% |
| 119 | GREAT WEST LIFE ASSURANCE#119 · 182,365 sh | 182,365 | $90.4M | 0.14% | -5.1% |
| 120 | HEALTHCARE OF ONTARIO PENSION PLAN FUND#120 · 177,679 sh | 177,679 | $88.3M | 0.12% | +64.1% |
| 121 | Mitsubishi UFJ & Banking#121 · 174,812 sh | 174,812 | $86.8M | 0.19% | +4.7% |
| 122 | NATIONAL BANK OF CANADA#122 · 172,898 sh | 172,898 | $85.9M | 0.06% | -36.5% |
| 123 | SCHRODER INVESTMENT MANAGEMENT GROUP#123 · 169,270 sh | 169,270 | $84.6M | 0.06% | +3.3% |
| 124 | CIBC Bancorp USA#124 · 166,673 sh | 166,673 | $82.8M | 0.10% | +160.6% |
| 125 | LORD, ABBETT#125 · 166,581 sh | 166,581 | $82.7M | 0.24% | 0.0% |
| 126 | Capital International#126 · 164,407 sh | 164,407 | $81.7M | 0.57% | +1.7% |
| 127 | Quantinno Capital Management#127 · 163,085 sh | 163,085 | $81.0M | 0.10% | +28.8% |
| 128 | Carmignac Gestion#128 · 163,045 sh | 163,045 | $81.0M | 1.05% | +10.0% |
| 129 | STIFEL FINANCIAL#129 · 162,151 sh | 162,151 | $80.5M | 0.07% | +0.7% |
| 130 | NOMURA ASSET MANAGEMENT INTERNATIONAL#130 · 159,549 sh | 159,549 | $79.3M | 0.12% | +2.0% |
| 131 | DANSKE BANK A/S#131 · 158,064 sh | 158,064 | $78.5M | 0.16% | +3.3% |
| 132 | MIRAE ASSET GLOBAL ETFS Ltd.#132 · 150,692 sh | 150,692 | $74.7M | 0.09% | -12.4% |
| 133 | Rockefeller Capital Management L.P.#133 · 149,476 sh | 149,476 | $74.2M | 0.11% | -0.1% |
| 134 | FJARDE AP-FONDEN /FOURTH SWEDISH NATIONAL PENSION FUND#134 · 148,682 sh | 148,682 | $73.9M | — | -0.9% |
| 135 | Harvest Portfolios Group#135 · 148,195 sh | 148,195 | $73.6M | 1.04% | New |
| 136 | Birch Hill Investment Advisors#136 · 147,702 sh | 147,702 | $73.4M | — | -2.1% |
| 137 | BALYASNY ASSET MANAGEMENT L.P.#137 · 145,005 sh | 145,005 | $72.0M | 0.09% | +261.3% |
| 138 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#138 · 144,174 sh | 144,174 | $71.6M | <0.01% | +613.0% |
| 139 | VAN ECK ASSOCIATES#139 · 143,881 sh | 143,881 | $71.5M | 0.04% | -1.5% |
| 140 | Allspring Global Investments#140 · 140,631 sh | 140,631 | $70.0M | 0.11% | +13.6% |
| 141 | Provident Investment Management#141 · 140,728 sh | 140,728 | $69.9M | — | -4.7% |
| 142 | Woodline Partners#142 · 140,288 sh | 140,288 | $69.7M | 0.22% | +4.0% |
| 143 | Asset Management One , Ltd.#143 · 139,597 sh | 139,597 | $69.3M | — | -1.7% |
| 144 | Man Group plc#144 · 139,233 sh | 139,233 | $69.2M | 0.11% | -41.2% |
| 145 | SEB Asset Management AB#145 · 138,097 sh | 138,097 | $68.6M | 0.26% | -2.0% |
| 146 | STATE OF WISCONSIN INVESTMENT BOARD#146 · 135,798 sh | 135,798 | $67.5M | 0.14% | -0.5% |
| 147 | TEACHER RETIREMENT SYSTEM OF TEXAS#147 · 135,619 sh | 135,619 | $67.4M | 0.18% | +9.1% |
| 148 | Connor, Clark & Lunn Investment Management Ltd.#148 · 135,236 sh | 135,236 | $67.2M | 0.13% | -46.3% |
| 149 | Mariner#149 · 134,614 sh | 134,614 | $66.9M | 0.07% | +2.3% |
| 150 | PRUDENTIAL FINANCIAL#150 · 133,294 sh | 133,294 | $66.2M | 0.07% | +1.3% |
| 151 | LOS ANGELES CAPITAL MANAGEMENT#151 · 130,802 sh | 130,802 | $65.0M | 0.24% | +101.4% |
| 152 | Vanguard Investments Australia, Ltd.#152 · 130,109 sh | 130,109 | $64.6M | 0.16% | +3.0% |
| 153 | SEI INVESTMENTS#153 · 129,981 sh | 129,981 | $64.6M | 0.06% | -2.4% |
| 154 | Focus Partners Wealth#154 · 128,958 sh | 128,958 | $64.1M | 0.07% | -1.9% |
| 155 | KBC Group NV#155 · 128,466 sh | 128,466 | $63.8M | — | +1.0% |
| 156 | Creative Planning#156 · 127,672 sh | 127,672 | $63.4M | 0.04% | +16.6% |
| 157 | ABN AMRO Bank N.V.#157 · 125,970 sh | 125,970 | $62.5M | 0.81% | +6.4% |
| 158 | BOWEN HANES#158 · 135,399 sh | 135,399 | $60.5M | 1.47% | 0.0% |
| 159 | NOMURA ASSET MANAGEMENT LTD#159 · 120,235 sh | 120,235 | $59.7M | 0.13% | -0.8% |
| 160 | CREDIT AGRICOLE S A#160 · 115,955 sh | 115,955 | $57.6M | 0.12% | -5.2% |
| 161 | GUGGENHEIM CAPITAL#161 · 115,233 sh | 115,233 | $57.2M | 0.36% | +14.8% |
| 162 | Treasurer of the State of North Carolina#162 · 108,303 sh | 108,303 | $53.8M | 0.14% | -0.3% |
| 163 | DnB Asset Management AS#163 · 108,106 sh | 108,106 | $53.7M | 0.15% | +0.7% |
| 164 | Banco Santander, S.A.#164 · 108,075 sh | 108,075 | $53.7M | 0.33% | +8.7% |
| 165 | STOREBRAND ASSET MANAGEMENT AS#165 · 107,628 sh | 107,628 | $53.5M | 0.13% | +4.9% |
| 166 | TRUIST FINANCIAL#166 · 106,967 sh | 106,967 | $53.1M | 0.06% | -6.5% |
| 167 | KLP KAPITALFORVALTNING AS#167 · 104,741 sh | 104,741 | $52.0M | 0.17% | +9.8% |
| 168 | CIBC Asset Management#168 · 104,292 sh | 104,292 | $51.8M | 0.11% | -2.4% |
| 169 | Corient Private Wealth#169 · 103,755 sh | 103,755 | $51.5M | 0.07% | +20.0% |
| 170 | Intermede Investment Partners Ltd#170 · 101,619 sh | 101,619 | $51.5M | 2.17% | -4.5% |
| 171 | MACKENZIE FINANCIAL#171 · 102,928 sh | 102,928 | $51.1M | 0.05% | +6.4% |
| 172 | COUNTRY BANK#172 · 100,360 sh | 100,360 | $49.9M | 0.87% | -4.5% |
| 173 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO#173 · 98,068 sh | 98,068 | $48.7M | 0.14% | -4.8% |
| 174 | Raiffeisen Bank International AG#174 · 97,170 sh | 97,170 | $48.6M | — | -4.2% |
| 175 | CAPITAL INTERNATIONAL LTD#175 · 97,334 sh | 97,334 | $48.3M | 1.58% | +1.5% |
| 176 | Toroso Investments#176 · 95,685 sh | 95,685 | $47.5M | 0.08% | +3.9% |
| 177 | Kovitz Investment Group Partners#177 · 95,246 sh | 95,246 | $47.3M | 1.05% | +4.8% |
| 178 | VIRGINIA RETIREMENT SYSTEMS ET Al#178 · 94,060 sh | 94,060 | $46.7M | 0.17% | 0.0% |
| 179 | PFA Pension, Forsikringsaktieselskab#179 · 93,959 sh | 93,959 | $46.7M | 0.12% | -30.4% |
| 180 | LAZARD ASSET MANAGEMENT#180 · 93,287 sh | 93,287 | $46.3M | 0.07% | -56.2% |
| 181 | State of Tennessee, Treasury Department#181 · 93,032 sh | 93,032 | $46.2M | 0.14% | +13.9% |
| 182 | Swiss Life Asset Management Ltd#182 · 91,614 sh | 91,614 | $45.5M | 0.19% | +10.9% |
| 183 | Susquehanna Portfolio Strategies#183 · 90,928 sh | 90,928 | $45.2M | 0.72% | +211.5% |
| 184 | Janney Montgomery Scott#184 · 85,735 sh | 85,735 | $42.6M | 0.08% | +1.7% |
| 185 | TORONTO DOMINION BANK#185 · 85,391 sh | 85,391 | $42.4M | 0.05% | +8.8% |
| 186 | ABN AMRO INVESTMENT SOLUTIONS#186 · 84,631 sh | 84,631 | $42.0M | — | +24.1% |
| 187 | Resona Asset Management ,Ltd.#187 · 84,092 sh | 84,092 | $41.8M | 0.20% | -6.9% |
| 188 | Eurizon Capital SGR S.p.A.#188 · 82,582 sh | 82,582 | $41.0M | 0.11% | +1.3% |
| 189 | State of New Jersey Common Pension Fund D#189 · 82,245 sh | 82,245 | $40.9M | 0.14% | -5.1% |
| 190 | FIFTH THIRD BANCORP#190 · 81,898 sh | 81,898 | $40.7M | 0.07% | -7.5% |
| 191 | Vontobel Holding Ltd.#191 · 81,525 sh | 81,525 | $40.5M | — | -2.2% |
| 192 | Lansforsakringar Fondforvaltning AB (publ)#192 · 79,627 sh | 79,627 | $39.6M | 0.18% | -5.0% |
| 193 | Cetera Investment Advisers#193 · 78,107 sh | 78,107 | $38.8M | 0.04% | +7.5% |
| 194 | Erste Asset Management GmbH#194 · 76,558 sh | 76,558 | $38.2M | 0.30% | -16.7% |
| 195 | NISSAY ASSET MANAGEMENT /JAPAN#195 · 75,743 sh | 75,743 | $37.6M | 0.16% | +6.0% |
| 196 | Calamos Advisors#196 · 75,388 sh | 75,388 | $37.4M | 0.12% | -3.2% |
| 197 | Mn Services Vermogensbeheer B.V.#197 · 74,100 sh | 74,100 | $36.8M | — | New |
| 198 | Pacer Advisors#198 · 72,465 sh | 72,465 | $36.0M | 0.09% | -18.5% |
| 199 | Czech National Bank#199 · 72,243 sh | 72,243 | $35.9M | — | +4.4% |
| 200 | Daiwa Securities Group#200 · 71,534 sh | 71,534 | $35.5M | 0.07% | +5.9% |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.