VERTEX PHARMACEUTICALS INC / MA (VRTX) — Institutional Holders, Q2 2026 (page 3)
1,768 institutional investment managers reported a VRTX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $119.6B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 201 to 300. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
VRTX 13F holders ranked 201–300 of 1,768
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 201 | CAPITAL FUND MANAGEMENT S.A.#201 · 71,088 sh | 71,088 | $35.3M | 0.16% | -42.2% |
| 202 | Arizona State Retirement System#202 · 70,580 sh | 70,580 | $35.1M | 0.18% | +1.5% |
| 203 | PNC FINANCIAL SERVICES GROUP#203 · 69,358 sh | 69,358 | $34.5M | 0.02% | -3.6% |
| 204 | STATE TREASURER STATE OF MICHIGAN#204 · 67,823 sh | 67,823 | $33.7M | — | -1.9% |
| 205 | GATEWAY INVESTMENT ADVISERS#205 · 67,289 sh | 67,289 | $33.4M | — | +0.3% |
| 206 | STRS OHIO#206 · 66,679 sh | 66,679 | $33.1M | 0.12% | -10.1% |
| 207 | Rafferty Asset Management#207 · 65,798 sh | 65,798 | $32.7M | 0.07% | +20.6% |
| 208 | Apollon Wealth Management#208 · 63,910 sh | 63,910 | $31.7M | — | +65.6% |
| 209 | Sumitomo Mitsui DS Asset Management Company, Ltd#209 · 63,330 sh | 63,330 | $31.5M | — | -0.8% |
| 210 | GF FUND MANAGEMENT LTD.#210 · 62,678 sh | 62,678 | $31.1M | — | -3.0% |
| 211 | Rakuten Investment Management#211 · 61,183 sh | 61,183 | $30.6M | 0.09% | +16.1% |
| 212 | ASSETMARK#212 · 61,055 sh | 61,055 | $30.3M | — | +1.8% |
| 213 | TRILLIUM ASSET MANAGEMENT#213 · 60,105 sh | 60,105 | $29.9M | 0.92% | -39.8% |
| 214 | Tredje AP-fonden#214 · 59,459 sh | 59,459 | $29.5M | 0.13% | -19.4% |
| 215 | NATIXIS#215 · 59,095 sh | 59,095 | $29.4M | 0.12% | +22.6% |
| 216 | FOSTER DYKEMA CABOT & PARTNERS#216 · 58,233 sh | 58,233 | $28.9M | 1.68% | +0.8% |
| 217 | MetLife Investment Management#217 · 58,072 sh | 58,072 | $28.8M | 0.13% | -18.0% |
| 218 | IFM Investors Pty Ltd#218 · 57,713 sh | 57,713 | $28.7M | — | +13.0% |
| 219 | JOHNSTON ASSET MANAGEMENT#219 · 57,683 sh | 57,683 | $28.7M | 1.01% | -1.2% |
| 220 | MOODY LYNN & LIEBERSON#220 · 56,624 sh | 56,624 | $28.1M | — | -1.8% |
| 221 | NISA INVESTMENT ADVISORS#221 · 56,455 sh | 56,455 | $28.0M | — | -3.0% |
| 222 | ATWOOD & PALMER#222 · 56,357 sh | 56,357 | $28.0M | — | +1.1% |
| 223 | COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS#223 · 56,059 sh | 56,059 | $27.8M | 0.14% | -5.3% |
| 224 | Hemenway#224 · 55,995 sh | 55,995 | $27.8M | 1.94% | +8.7% |
| 225 | ZACKS INVESTMENT MANAGEMENT#225 · 55,052 sh | 55,052 | $27.3M | 0.19% | -0.1% |
| 226 | Edgemoor Investment Advisors#226 · 55,020 sh | 55,020 | $27.3M | 1.86% | -0.7% |
| 227 | Reynders McVeigh Capital Management#227 · 54,499 sh | 54,499 | $27.1M | 1.20% | -0.3% |
| 228 | PensionDanmark Pensionsforsikringsaktieselskab#228 · 54,094 sh | 54,094 | $26.9M | — | +9.9% |
| 229 | BEACON INVESTMENT ADVISORY SERVICES#229 · 53,380 sh | 53,380 | $26.5M | — | -4.9% |
| 230 | Retirement Systems of Alabama#230 · 53,319 sh | 53,319 | $26.5M | 0.08% | -1.1% |
| 231 | CULLINAN ASSOCIATES#231 · 51,762 sh | 51,762 | $25.7M | 1.94% | 0.0% |
| 232 | VALLEY WEALTH MANAGERS#232 · 51,329 sh | 51,329 | $25.5M | — | +2.4% |
| 233 | CITIZENS FINANCIAL GROUP#233 · 50,988 sh | 50,988 | $25.3M | — | +2.3% |
| 234 | PINEBRIDGE INVESTMENTS#234 · 50,819 sh | 50,819 | $25.2M | 0.21% | -7.8% |
| 235 | COMMONWEALTH EQUITY SERVICES#235 · 50,813 sh | 50,813 | $25.2M | 0.03% | -7.6% |
| 236 | Empowered Funds#236 · 50,197 sh | 50,197 | $24.9M | 0.13% | +20.3% |
| 237 | OSAIC#237 · 49,586 sh | 49,586 | $24.6M | 0.03% | +12.8% |
| 238 | HighTower Advisors#238 · 49,020 sh | 49,020 | $24.3M | 0.02% | -25.4% |
| 239 | USS Investment Management Ltd#239 · 48,893 sh | 48,893 | $24.3M | 0.09% | +3.7% |
| 240 | DAVIDSON INVESTMENT ADVISORS#240 · 48,710 sh | 48,710 | $24.2M | — | -22.5% |
| 241 | China Universal Asset Management , Ltd.#241 · 48,265 sh | 48,265 | $24.0M | 1.43% | +9.9% |
| 242 | AMALGAMATED BANK#242 · 47,716 sh | 47,716 | $23.7M | — | -10.4% |
| 243 | ADAMS DIVERSIFIED EQUITY FUND#243 · 47,300 sh | 47,300 | $23.5M | — | New |
| 244 | Quadrature Capital Ltd#244 · 46,945 sh | 46,945 | $23.3M | 0.20% | New |
| 245 | C WorldWide Group Holding A/S#245 · 46,057 sh | 46,057 | $22.9M | 0.55% | 0.0% |
| 246 | Pathstone#246 · 45,952 sh | 45,952 | $22.9M | 0.07% | +3.8% |
| 247 | XPONANCE#247 · 45,980 sh | 45,980 | $22.8M | 0.14% | -35.0% |
| 248 | OSSIAM#248 · 45,879 sh | 45,879 | $22.8M | 0.30% | +16.6% |
| 249 | Lido Advisors#249 · 45,347 sh | 45,347 | $22.5M | 0.06% | +4.2% |
| 250 | W.G. Shaheen & Associates DBA Whitney#250 · 44,714 sh | 44,714 | $22.2M | 1.62% | +1.4% |
| 251 | Zurich Insurance Group Ltd#251 · 43,589 sh | 43,589 | $21.7M | 0.15% | -2.3% |
| 252 | WEALTH ENHANCEMENT ADVISORY SERVICES#252 · 45,889 sh | 45,889 | $21.5M | — | +12.8% |
| 253 | NEW YORK LIFE INVESTMENT MANAGEMENT#253 · 43,218 sh | 43,218 | $21.5M | 0.15% | +13.5% |
| 254 | Vanguard Personalized Indexing Management#254 · 43,151 sh | 43,151 | $21.4M | 0.18% | +3.7% |
| 255 | MARTINGALE ASSET MANAGEMENT L P#255 · 42,729 sh | 42,729 | $21.2M | 0.50% | -4.5% |
| 256 | FEDERATED HERMES#256 · 42,663 sh | 42,663 | $21.2M | 0.03% | -40.6% |
| 257 | ACADIAN ASSET MANAGEMENT#257 · 42,122 sh | 42,122 | $20.9M | 0.02% | +62.8% |
| 258 | O'SHAUGHNESSY ASSET MANAGEMENT#258 · 42,063 sh | 42,063 | $20.9M | 0.10% | -32.0% |
| 259 | Wealthfront Advisers#259 · 41,608 sh | 41,608 | $20.7M | 0.04% | -10.3% |
| 260 | PUBLIC SECTOR PENSION INVESTMENT BOARD#260 · 41,334 sh | 41,334 | $20.5M | 0.05% | +0.4% |
| 261 | Varma Mutual Pension Insurance#261 · 40,826 sh | 40,826 | $20.3M | 0.11% | -6.4% |
| 262 | HRT FINANCIAL#262 · 40,533 sh | 40,533 | $20.1M | 0.05% | +51.3% |
| 263 | Tweedy, Browne#263 · 40,121 sh | 40,121 | $19.9M | 1.51% | -0.7% |
| 264 | FLPUTNAM INVESTMENT MANAGEMENT#264 · 40,116 sh | 40,116 | $19.9M | 0.24% | +1.6% |
| 265 | Integral Health Asset Management#265 · 40,000 sh | 40,000 | $19.9M | 0.78% | 0.0% |
| 266 | Sanctuary Advisors#266 · 39,811 sh | 39,811 | $19.8M | 0.09% | -19.3% |
| 267 | BANCO BILBAO VIZCAYA ARGENTARIA, S.A.#267 · 39,809 sh | 39,809 | $19.7M | 0.12% | -2.4% |
| 268 | Americana Partners#268 · 38,914 sh | 38,914 | $19.3M | 0.44% | +30.7% |
| 269 | MML INVESTORS SERVICES#269 · 38,907 sh | 38,907 | $19.3M | 0.04% | +16.4% |
| 270 | FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A.#270 · 38,752 sh | 38,752 | $19.2M | — | +10.7% |
| 271 | Utah Retirement Systems#271 · 38,602 sh | 38,602 | $19.2M | 0.18% | -6.5% |
| 272 | Nippon Life Global Investors Americas#272 · 38,230 sh | 38,230 | $19.0M | 0.76% | +1429.2% |
| 273 | BRITISH COLUMBIA INVESTMENT MANAGEMENT#273 · 38,144 sh | 38,144 | $18.9M | 0.12% | +9.1% |
| 274 | Police & Firemen's Retirement System of New Jersey#274 · 37,982 sh | 37,982 | $18.9M | 0.14% | -2.8% |
| 275 | MACQUARIE GROUP LTD#275 · 37,980 sh | 37,980 | $18.9M | 0.08% | -5.6% |
| 276 | Aristotle Atlantic Partners#276 · 37,489 sh | 37,489 | $18.6M | 0.77% | -0.1% |
| 277 | IEQ CAPITAL#277 · 37,339 sh | 37,339 | $18.5M | 0.09% | +37.4% |
| 278 | BAILARD#278 · 37,314 sh | 37,314 | $18.5M | — | -1.4% |
| 279 | SEGALL BRYANT & HAMILL#279 · 37,072 sh | 37,072 | $18.4M | 0.22% | +23.6% |
| 280 | TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY#280 · 36,725 sh | 36,725 | $18.2M | 0.12% | 0.0% |
| 281 | CAPTRUST FINANCIAL ADVISORS#281 · 35,471 sh | 35,471 | $17.6M | 0.03% | +10.5% |
| 282 | BI Asset Management Fondsmaeglerselskab A/S#282 · 35,137 sh | 35,137 | $17.5M | — | -29.1% |
| 283 | Illinois Municipal Retirement Fund#283 · 34,259 sh | 34,259 | $17.0M | 0.19% | -15.6% |
| 284 | Ilmarinen Mutual Pension Insurance#284 · 33,800 sh | 33,800 | $16.8M | 0.11% | 0.0% |
| 285 | Caprock Group#285 · 33,721 sh | 33,721 | $16.8M | 0.32% | +12.4% |
| 286 | MIZUHO SECURITIES USA#286 · 35,225 sh | 35,225 | $16.7M | 0.16% | +129.4% |
| 287 | Elo Mutual Pension Insurance#287 · 33,374 sh | 33,374 | $16.6M | 0.21% | +6.4% |
| 288 | MCRAE CAPITAL MANAGEMENT#288 · 33,191 sh | 33,191 | $16.5M | — | -2.7% |
| 289 | WILLIAM BLAIR INVESTMENT MANAGEMENT#289 · 32,172 sh | 32,172 | $16.0M | 0.05% | -18.6% |
| 290 | US BANCORP \DE\#290 · 32,020 sh | 32,020 | $15.9M | 0.02% | +7.5% |
| 291 | State of Alaska, Department of Revenue#291 · 31,836 sh | 31,836 | $15.8M | — | -4.1% |
| 292 | AIA Group Ltd#292 · 31,601 sh | 31,601 | $15.7M | 0.20% | +7.0% |
| 293 | OREGON PUBLIC EMPLOYEES RETIREMENT FUND#293 · 31,235 sh | 31,235 | $15.5M | 0.17% | +7.4% |
| 294 | BARLOW WEALTH PARTNERS#294 · 30,786 sh | 30,786 | $15.3M | — | +1.2% |
| 295 | Vinva Investment Management Ltd#295 · 30,687 sh | 30,687 | $15.3M | 0.10% | +222.0% |
| 296 | MERCER GLOBAL ADVISORS#296 · 30,705 sh | 30,705 | $15.3M | 0.02% | +34.9% |
| 297 | Rhenman & Partners Asset Management AB#297 · 30,685 sh | 30,685 | $15.2M | 1.44% | -29.4% |
| 298 | NORDEA INVESTMENT MANAGEMENT AB#298 · 30,496 sh | 30,496 | $15.1M | 0.01% | +12.2% |
| 299 | Foster Victor Wealth Advisors#299 · 31,606 sh | 31,606 | $15.1M | — | +2.8% |
| 300 | Longaeva Partners L.P.#300 · 30,279 sh | 30,279 | $15.0M | 0.33% | +21.4% |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.