VERTEX PHARMACEUTICALS INC / MA (VRTX) — Institutional Holders, Q2 2026 (page 4)
1,768 institutional investment managers reported a VRTX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $119.6B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 301 to 400. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
VRTX 13F holders ranked 301–400 of 1,768
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 301 | Atria Investments#301 · 30,245 sh | 30,245 | $15.0M | — | +10.6% |
| 302 | TUDOR INVESTMENT ET AL#302 · 30,176 sh | 30,176 | $15.0M | 0.02% | New |
| 303 | iA Global Asset Management#303 · 30,054 sh | 30,054 | $14.9M | 0.18% | -2.8% |
| 304 | Galvin, Gaustad & Stein#304 · 29,760 sh | 29,760 | $14.8M | — | -15.5% |
| 305 | SHELTON CAPITAL MANAGEMENT#305 · 29,423 sh | 29,423 | $14.6M | 0.27% | -19.1% |
| 306 | Madison Asset Management#306 · 29,302 sh | 29,302 | $14.6M | 0.17% | +7.0% |
| 307 | Louisiana State Employees Retirement System#307 · 29,300 sh | 29,300 | $14.6M | — | -1.0% |
| 308 | NOMURA#308 · 29,198 sh | 29,198 | $14.5M | 0.02% | +11.9% |
| 309 | CI INVESTMENTS#309 · 28,775 sh | 28,775 | $14.3M | 0.05% | +105.5% |
| 310 | OP Asset Management Ltd#310 · 28,450 sh | 28,450 | $14.1M | 0.15% | +8.6% |
| 311 | MassMutual Private Wealth & , FSB#311 · 28,385 sh | 28,385 | $14.1M | — | -1.2% |
| 312 | Avanza Fonder AB#312 · 28,198 sh | 28,198 | $14.0M | — | +2.0% |
| 313 | UniSuper Management Pty Ltd#313 · 27,989 sh | 27,989 | $13.9M | — | +42.4% |
| 314 | Danica Pension, Livsforsikringsaktieselskab#314 · 27,829 sh | 27,829 | $13.8M | 0.22% | +6.5% |
| 315 | HUNTINGTON NATIONAL BANK#315 · 27,754 sh | 27,754 | $13.8M | 0.07% | -4.7% |
| 316 | Bogart Wealth#316 · 27,703 sh | 27,703 | $13.8M | 0.47% | +1.9% |
| 317 | CIBC WORLD MARKET#317 · 27,626 sh | 27,626 | $13.7M | 0.02% | -1.6% |
| 318 | BANK OF NOVA SCOTIA#318 · 27,607 sh | 27,607 | $13.7M | 0.02% | -21.9% |
| 319 | Shelter Mutual Insurance#319 · 27,600 sh | 27,600 | $13.7M | 2.90% | 0.0% |
| 320 | Allianz Asset Management GmbH#320 · 30,458 sh | 30,458 | $13.6M | 0.01% | -11.3% |
| 321 | Vestcor#321 · 27,242 sh | 27,242 | $13.5M | 0.33% | -19.9% |
| 322 | Heirloom Wealth Management#322 · 26,965 sh | 26,965 | $13.4M | — | +15.0% |
| 323 | Cinctive Capital Management#323 · 26,712 sh | 26,712 | $13.3M | 0.49% | +429.1% |
| 324 | FIL Ltd#324 · 26,508 sh | 26,508 | $13.2M | <0.01% | +22.6% |
| 325 | FAGAN ASSOCIATES#325 · 26,429 sh | 26,429 | $13.1M | — | -0.5% |
| 326 | BENDER ROBERT & ASSOCIATES#326 · 26,303 sh | 26,303 | $13.1M | — | +0.5% |
| 327 | CCM INVESTMENT ADVISERS#327 · 26,270 sh | 26,270 | $13.0M | 1.01% | +1.5% |
| 328 | CAPITOLIS LIQUID GLOBAL MARKETS#328 · 26,249 sh | 26,249 | $13.0M | 0.06% | +56.2% |
| 329 | MUTUAL OF AMERICA CAPITAL MANAGEMENT#329 · 26,109 sh | 26,109 | $13.0M | — | -3.2% |
| 330 | Advisors Asset Management#330 · 25,909 sh | 25,909 | $12.9M | 0.20% | +6.6% |
| 331 | WILEY BROS.-AINTREE CAPITAL#331 · 25,535 sh | 25,535 | $12.7M | 0.05% | +9.2% |
| 332 | ASR Vermogensbeheer N.V.#332 · 25,471 sh | 25,471 | $12.7M | — | -4.6% |
| 333 | Liontrust Investment Partners LLP#333 · 25,460 sh | 25,460 | $12.6M | 0.19% | +69.2% |
| 334 | Norinchukin Bank, The#334 · 25,275 sh | 25,275 | $12.6M | 0.12% | +0.9% |
| 335 | Savant Capital#335 · 26,241 sh | 26,241 | $12.5M | 0.04% | +580.5% |
| 336 | Biondo Investment Advisors#336 · 25,145 sh | 25,145 | $12.5M | 1.53% | -0.7% |
| 337 | LVM CAPITAL MANAGEMENT LTD#337 · 24,986 sh | 24,986 | $12.4M | — | -3.3% |
| 338 | GRANDFIELD & DODD#338 · 24,838 sh | 24,838 | $12.3M | 0.65% | +14.4% |
| 339 | Cornerstone Advisors#339 · 24,760 sh | 24,760 | $12.3M | 0.41% | New |
| 340 | Fisher Asset Management#340 · 24,478 sh | 24,478 | $12.2M | <0.01% | -21.4% |
| 341 | Telos Capital Management#341 · 24,289 sh | 24,289 | $12.1M | 1.06% | +4.5% |
| 342 | ALLIANZ SE#342 · 23,921 sh | 23,921 | $11.9M | 0.13% | 0.0% |
| 343 | Andra AP-fonden#343 · 23,743 sh | 23,743 | $11.8M | 0.14% | -0.7% |
| 344 | BANQUE PICTET & CIE SA#344 · 23,496 sh | 23,496 | $11.7M | — | -17.7% |
| 345 | PROFUND ADVISORS#345 · 23,398 sh | 23,398 | $11.6M | 0.32% | +1.1% |
| 346 | LEUCADIA NATIONAL#346 · 23,154 sh | 23,154 | $11.5M | 0.08% | -2.8% |
| 347 | Waverly Advisors#347 · 23,131 sh | 23,131 | $11.5M | 0.07% | +0.3% |
| 348 | Skandinaviska Enskilda Banken AB (publ)#348 · 23,000 sh | 23,000 | $11.4M | 0.43% | -50.0% |
| 349 | Eurizon SLJ Capital Ltd#349 · 22,969 sh | 22,969 | $11.4M | 4.21% | +6.7% |
| 350 | KENNEDY CAPITAL MANAGEMENT#350 · 22,838 sh | 22,838 | $11.3M | 0.20% | -0.7% |
| 351 | MUFG Securities EMEA plc#351 · 22,809 sh | 22,809 | $11.3M | 0.12% | +119.0% |
| 352 | CARY STREET PARTNERS FINANCIAL#352 · 22,571 sh | 22,571 | $11.2M | 0.24% | +0.5% |
| 353 | SIG BROKERAGE#353 · 22,390 sh | 22,390 | $11.1M | 0.22% | +27.2% |
| 354 | PINNACLE ASSOCIATES LTD#354 · 22,375 sh | 22,375 | $11.1M | — | +3.6% |
| 355 | Horizon Investments#355 · 22,215 sh | 22,215 | $11.0M | 0.12% | -9.1% |
| 356 | ALLSTATE#356 · 22,006 sh | 22,006 | $10.9M | 0.11% | +2.2% |
| 357 | Cambridge Investment Research Advisors#357 · 21,946 sh | 21,946 | $10.9M | 0.02% | +37.5% |
| 358 | YOUSIF CAPITAL MANAGEMENT#358 · 21,685 sh | 21,685 | $10.8M | — | -7.2% |
| 359 | QRG CAPITAL MANAGEMENT#359 · 21,665 sh | 21,665 | $10.8M | 0.09% | +8.9% |
| 360 | Capital Group Investment Management Pte. Ltd.#360 · 21,388 sh | 21,388 | $10.6M | 1.60% | +1.4% |
| 361 | Diversify Advisory Services#361 · 22,168 sh | 22,168 | $10.6M | — | +2159.7% |
| 362 | DIVERSIFY WEALTH MANAGEMENT#362 · 22,168 sh | 22,168 | $10.6M | — | -0.3% |
| 363 | WASHINGTON BANK#363 · 21,320 sh | 21,320 | $10.6M | 0.74% | -14.5% |
| 364 | Osmosis Investment Management UK Ltd#364 · 21,075 sh | 21,075 | $10.5M | 0.49% | -28.8% |
| 365 | OMERS ADMINISTRATION#365 · 21,073 sh | 21,073 | $10.5M | 0.06% | +12.1% |
| 366 | Fideuram Asset Management (Ireland) dac#366 · 23,431 sh | 23,431 | $10.4M | 0.20% | New |
| 367 | Ethic#367 · 20,947 sh | 20,947 | $10.4M | 0.13% | +17.0% |
| 368 | Steward Partners Investment Advisory#368 · 20,851 sh | 20,851 | $10.4M | 0.05% | +16.7% |
| 369 | CAMDEN NATIONAL BANK#369 · 20,831 sh | 20,831 | $10.3M | 1.35% | -0.4% |
| 370 | GW HENSSLER & ASSOCIATES LTD#370 · 20,690 sh | 20,690 | $10.3M | — | +0.2% |
| 371 | INTECH INVESTMENT MANAGEMENT#371 · 20,520 sh | 20,520 | $10.2M | 0.09% | +4.1% |
| 372 | Gulf International Bank (UK) Ltd#372 · 20,389 sh | 20,389 | $10.1M | — | +3.8% |
| 373 | THRIVENT FINANCIAL FOR LUTHERANS#373 · 20,169 sh | 20,169 | $10.0M | 0.02% | -73.5% |
| 374 | Federation des caisses Desjardins du Quebec#374 · 20,094 sh | 20,094 | $10.0M | 0.03% | +25.9% |
| 375 | Modera Wealth Management#375 · 20,033 sh | 20,033 | $10.0M | 0.11% | -3.2% |
| 376 | AIMZ Investment Advisors#376 · 19,931 sh | 19,931 | $9.9M | 2.72% | -0.1% |
| 377 | Pinnacle Financial Partners#377 · 19,848 sh | 19,848 | $9.9M | 0.07% | +3.2% |
| 378 | PRUDENTIAL PLC#378 · 19,710 sh | 19,710 | $9.8M | 0.05% | +12.5% |
| 379 | Broderick Brian C#379 · 19,549 sh | 19,549 | $9.7M | 1.50% | +4.8% |
| 380 | Harvest Fund Management , Ltd#380 · 19,560 sh | 19,560 | $9.7M | 0.32% | +0.4% |
| 381 | EULAV Asset Management#381 · 19,500 sh | 19,500 | $9.7M | — | -7.1% |
| 382 | Boston Common Asset Management#382 · 19,493 sh | 19,493 | $9.7M | — | +13.3% |
| 383 | FIDUCIARY#383 · 19,400 sh | 19,400 | $9.6M | 0.10% | -2.4% |
| 384 | HealthInvest Partners AB#384 · 19,131 sh | 19,131 | $9.5M | 2.56% | -16.8% |
| 385 | Gotham Asset Management#385 · 18,986 sh | 18,986 | $9.4M | 0.02% | -9.1% |
| 386 | STRATEGIC PLANNING GROUP#386 · 18,666 sh | 18,666 | $9.3M | — | +7.3% |
| 387 | NewEdge Advisors#387 · 18,435 sh | 18,435 | $9.2M | 0.03% | New |
| 388 | Bleakley Financial Group#388 · 18,400 sh | 18,400 | $9.1M | 0.12% | +6.8% |
| 389 | BLAIR WILLIAM#389 · 18,400 sh | 18,400 | $9.1M | 0.02% | +11.2% |
| 390 | Capital Group Private Client Services#390 · 18,365 sh | 18,365 | $9.1M | 0.13% | -4.5% |
| 391 | CULLEN/FROST BANKERS#391 · 18,291 sh | 18,291 | $9.1M | 0.09% | +10.4% |
| 392 | SAPIENT CAPITAL#392 · 18,011 sh | 18,011 | $8.9M | — | -5.2% |
| 393 | OPPENHEIMER ASSET MANAGEMENT#393 · 17,931 sh | 17,931 | $8.9M | 0.09% | +3.6% |
| 394 | Third View Private Wealth#394 · 17,866 sh | 17,866 | $8.9M | 1.09% | +5.7% |
| 395 | Azimuth Capital Investment Management#395 · 17,818 sh | 17,818 | $8.9M | 0.30% | -4.5% |
| 396 | Saudi Central Bank#396 · 17,805 sh | 17,805 | $8.8M | 0.12% | +90.1% |
| 397 | Brevan Howard Capital Management#397 · 17,622 sh | 17,622 | $8.8M | 0.06% | +459.1% |
| 398 | Motley Fool Asset Management#398 · 17,288 sh | 17,288 | $8.6M | 0.33% | -14.8% |
| 399 | Beacon Pointe Advisors#399 · 17,047 sh | 17,047 | $8.5M | 0.04% | -4.7% |
| 400 | Chicago Capital#400 · 17,029 sh | 17,029 | $8.5M | — | +40.5% |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.