VERTEX PHARMACEUTICALS INC / MA (VRTX) — Institutional Holders, Q2 2026 (page 6)
1,768 institutional investment managers reported a VRTX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $119.6B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 501 to 600. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
VRTX 13F holders ranked 501–600 of 1,768
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 501 | ASHFORD CAPITAL MANAGEMENT#501 · 9,078 sh | 9,078 | $4.5M | 0.48% | 0.0% |
| 502 | Lombard Odier Asset Management (Switzerland) SA#502 · 9,072 sh | 9,072 | $4.5M | 0.14% | -2.6% |
| 503 | TEMA ETFS#503 · 9,060 sh | 9,060 | $4.5M | — | -6.0% |
| 504 | Traynor Capital Management#504 · 9,049 sh | 9,049 | $4.5M | 0.21% | -23.4% |
| 505 | UNIVEST FINANCIAL#505 · 9,049 sh | 9,049 | $4.5M | 0.22% | +28.1% |
| 506 | Canal Capital Management#506 · 9,045 sh | 9,045 | $4.5M | 0.55% | New |
| 507 | Aware Super Pty Ltd as trustee of Aware Super#507 · 9,038 sh | 9,038 | $4.5M | 0.06% | New |
| 508 | EP Wealth Advisors#508 · 9,027 sh | 9,027 | $4.5M | 0.02% | +4.5% |
| 509 | Sivik Global Healthcare#509 · 10,000 sh | 10,000 | $4.5M | — | 0.0% |
| 510 | Empirical Finance#510 · 8,986 sh | 8,986 | $4.5M | 0.19% | +3.4% |
| 511 | Machina Capital S.A.S.#511 · 8,966 sh | 8,966 | $4.5M | 0.71% | -7.1% |
| 512 | Perigon Wealth Management#512 · 8,834 sh | 8,834 | $4.4M | — | +36.9% |
| 513 | E. Ohman J:or Asset Management AB#513 · 8,823 sh | 8,823 | $4.4M | — | 0.0% |
| 514 | BROWN BROTHERS HARRIMAN#514 · 8,785 sh | 8,785 | $4.4M | 0.02% | +50.5% |
| 515 | Sterling Capital Management#515 · 8,648 sh | 8,648 | $4.3M | — | -35.2% |
| 516 | Sepio Capital#516 · 8,623 sh | 8,623 | $4.3M | — | +4.0% |
| 517 | MASTERINVEST Kapitalanlage GmbH#517 · 8,519 sh | 8,519 | $4.2M | 0.36% | +2.7% |
| 518 | Bensler#518 · 8,506 sh | 8,506 | $4.2M | 0.37% | +3.0% |
| 519 | Notis-McConarty Edward#519 · 8,423 sh | 8,423 | $4.2M | 1.81% | +2.0% |
| 520 | RDA Financial Network#520 · 8,419 sh | 8,419 | $4.2M | — | +17.2% |
| 521 | Cumberland Partners Ltd#521 · 8,368 sh | 8,368 | $4.2M | 0.27% | -10.8% |
| 522 | Quantitative Investment Management#522 · 8,342 sh | 8,342 | $4.1M | 0.45% | New |
| 523 | Dempze Nancy E#523 · 8,282 sh | 8,282 | $4.1M | 1.97% | +6.0% |
| 524 | Y-Intercept (Hong Kong) Ltd#524 · 8,281 sh | 8,281 | $4.1M | — | -76.9% |
| 525 | MISSION WEALTH MANAGEMENT#525 · 8,170 sh | 8,170 | $4.1M | — | +99.5% |
| 526 | NORTHWESTERN MUTUAL INVESTMENT MANAGEMENT COMPANY#526 · 8,137 sh | 8,137 | $4.0M | 0.05% | +0.1% |
| 527 | Howard Capital Management#527 · 8,113 sh | 8,113 | $4.0M | — | +104.4% |
| 528 | Linden Thomas Advisory Services#528 · 8,103 sh | 8,103 | $4.0M | — | -0.2% |
| 529 | Envestnet Portfolio Solutions#529 · 8,064 sh | 8,064 | $4.0M | 0.02% | -7.3% |
| 530 | BRIGHTON JONES#530 · 8,048 sh | 8,048 | $4.0M | 0.07% | +19.1% |
| 531 | COMMERCE BANK#531 · 8,033 sh | 8,033 | $4.0M | 0.02% | +6.6% |
| 532 | Cresset Asset Management#532 · 7,926 sh | 7,926 | $3.9M | 0.01% | +0.8% |
| 533 | GABELLI FUNDS#533 · 7,891 sh | 7,891 | $3.9M | 0.03% | -0.4% |
| 534 | Vise Technologies#534 · 7,882 sh | 7,882 | $3.9M | 0.04% | +49.9% |
| 535 | BALDWIN WEALTH PARTNERS#535 · 7,824 sh | 7,824 | $3.9M | — | 0.0% |
| 536 | J.P. Marvel Investment Advisors#536 · 7,810 sh | 7,810 | $3.9M | 0.45% | -0.6% |
| 537 | Vestmark Advisory Solutions#537 · 7,762 sh | 7,762 | $3.9M | 0.04% | +11.6% |
| 538 | BLI - Banque de Luxembourg Investments#538 · 7,700 sh | 7,700 | $3.9M | 0.14% | +40.0% |
| 539 | MUFG SECURITIES AMERICAS#539 · 7,645 sh | 7,645 | $3.8M | 0.20% | +8.8% |
| 540 | BROWN ADVISORY#540 · 7,562 sh | 7,562 | $3.8M | <0.01% | -1.2% |
| 541 | North Dakota State Investment Board#541 · 7,547 sh | 7,547 | $3.7M | 0.15% | +1.3% |
| 542 | EagleClaw Capital Managment#542 · 7,535 sh | 7,535 | $3.7M | 0.50% | +2.0% |
| 543 | Hedeker Wealth#543 · 7,515 sh | 7,515 | $3.7M | — | -1.5% |
| 544 | Graphene Investments SAS#544 · 7,500 sh | 7,500 | $3.7M | — | +13.6% |
| 545 | AIGEN INVESTMENT MANAGEMENT#545 · 7,452 sh | 7,452 | $3.7M | 1.01% | +75.8% |
| 546 | CERTUITY#546 · 7,449 sh | 7,449 | $3.7M | 0.18% | +25.6% |
| 547 | Summit Trail Advisors#547 · 7,429 sh | 7,429 | $3.7M | 0.05% | +2.5% |
| 548 | JOHNSON INVESTMENT COUNSEL#548 · 7,360 sh | 7,360 | $3.7M | 0.03% | +0.2% |
| 549 | LEGACY CAPITAL WEALTH MANAGEMENT#549 · 7,333 sh | 7,333 | $3.6M | 1.67% | +25.4% |
| 550 | First National Bank of Mount Dora, Investment Services#550 · 7,194 sh | 7,194 | $3.6M | — | -0.2% |
| 551 | Crestwood Advisors Group#551 · 7,184 sh | 7,184 | $3.6M | 0.05% | -7.4% |
| 552 | Summit Global Investments#552 · 7,182 sh | 7,182 | $3.6M | 0.19% | +84.3% |
| 553 | MIROVA#553 · 7,071 sh | 7,071 | $3.5M | 0.13% | -31.9% |
| 554 | Catalyst Funds Management Pty Ltd#554 · 7,001 sh | 7,001 | $3.5M | 0.19% | +625.5% |
| 555 | Integrated Wealth Concepts#555 · 6,994 sh | 6,994 | $3.5M | 0.02% | +49.8% |
| 556 | SCOTIA CAPITAL#556 · 6,981 sh | 6,981 | $3.5M | 0.01% | +43.6% |
| 557 | GAMMA Investing#557 · 6,918 sh | 6,918 | $3.4M | — | +4.9% |
| 558 | COMMERZBANK AKTIENGESELLSCHAFT#558 · 6,857 sh | 6,857 | $3.4M | 0.07% | -5.8% |
| 559 | NORTH STAR ASSET MANAGEMENT#559 · 6,833 sh | 6,833 | $3.4M | 0.13% | -0.4% |
| 560 | ASSOCIATED BANC#560 · 6,791 sh | 6,791 | $3.4M | 0.08% | -0.4% |
| 561 | South Dakota Investment Council#561 · 6,760 sh | 6,760 | $3.4M | 0.06% | +5.6% |
| 562 | Northwest & Ethical Investments L.P.#562 · 6,664 sh | 6,664 | $3.3M | 0.08% | -44.2% |
| 563 | Kentucky Retirement Systems Insurance Fund#563 · 6,649 sh | 6,649 | $3.3M | 0.20% | -1.8% |
| 564 | CENTRAL#564 · 6,641 sh | 6,641 | $3.3M | 0.06% | -4.6% |
| 565 | Vision Capital Management#565 · 6,630 sh | 6,630 | $3.3M | — | -1.0% |
| 566 | SECURIAN ASSET MANAGEMENT#566 · 6,767 sh | 6,767 | $3.3M | 0.12% | -1.9% |
| 567 | BOKF, NA#567 · 6,560 sh | 6,560 | $3.3M | 0.04% | +10.5% |
| 568 | SUMITOMO LIFE INSURANCE#568 · 6,558 sh | 6,558 | $3.3M | 0.05% | -15.4% |
| 569 | Lighthouse Financial#569 · 6,515 sh | 6,515 | $3.2M | — | +3.8% |
| 570 | CHOREO#570 · 6,474 sh | 6,474 | $3.2M | 0.04% | +5.0% |
| 571 | Canada Post Registered Pension Plan#571 · 6,474 sh | 6,474 | $3.2M | 0.11% | 0.0% |
| 572 | Meeder Advisory Services#572 · 6,415 sh | 6,415 | $3.2M | 0.12% | +3.5% |
| 573 | THOMPSON SIEGEL & WALMSLEY#573 · 6,408 sh | 6,408 | $3.2M | 0.06% | -0.5% |
| 574 | Kintegral Advisory#574 · 6,397 sh | 6,397 | $3.2M | — | 0.0% |
| 575 | Aster Capital Management (DIFC) Ltd#575 · 6,302 sh | 6,302 | $3.1M | 0.67% | New |
| 576 | Glenview#576 · 6,995 sh | 6,995 | $3.1M | 0.05% | 0.0% |
| 577 | MCCARTER PRIVATE WEALTH SERVICES#577 · 6,249 sh | 6,249 | $3.1M | — | -6.4% |
| 578 | MONTCHANIN ASSET MANAGEMENT#578 · 6,232 sh | 6,232 | $3.1M | 3.16% | -10.1% |
| 579 | BOOTHBAY FUND MANAGEMENT#579 · 6,174 sh | 6,174 | $3.1M | 0.04% | +367.7% |
| 580 | COLDSTREAM CAPITAL MANAGEMENT#580 · 6,151 sh | 6,151 | $3.1M | 0.04% | -5.9% |
| 581 | GRIFFIN ASSET MANAGEMENT#581 · 6,142 sh | 6,142 | $3.1M | — | -0.5% |
| 582 | Financial Advisors Network#582 · 6,125 sh | 6,125 | $3.0M | 0.37% | +5.1% |
| 583 | CSM Advisors#583 · 6,133 sh | 6,133 | $3.0M | 0.06% | -43.4% |
| 584 | Compound Planning#584 · 6,108 sh | 6,108 | $3.0M | 0.08% | -8.4% |
| 585 | Wahed Invest#585 · 6,050 sh | 6,050 | $3.0M | 0.31% | -5.7% |
| 586 | Plato Investment Management Ltd#586 · 6,083 sh | 6,083 | $3.0M | 0.17% | +2.5% |
| 587 | BAMCO#587 · 6,000 sh | 6,000 | $3.0M | <0.01% | -20.0% |
| 588 | Cohen Klingenstein#588 · 6,000 sh | 6,000 | $3.0M | — | 0.0% |
| 589 | Phoenix Financial Ltd.#589 · 5,993 sh | 5,993 | $3.0M | 0.02% | +24.0% |
| 590 | HALL LAURIE J TRUSTEE#590 · 5,990 sh | 5,990 | $3.0M | — | +0.5% |
| 591 | PRINCIPAL SECURITIES#591 · 5,982 sh | 5,982 | $3.0M | 0.04% | -9.1% |
| 592 | Westview Management dba Westview Investment Advisors#592 · 5,981 sh | 5,981 | $3.0M | 1.45% | +2.2% |
| 593 | Freedom Day Solutions#593 · 5,934 sh | 5,934 | $2.9M | — | +0.3% |
| 594 | Harbour Capital Advisors#594 · 6,051 sh | 6,051 | $2.9M | — | +1.0% |
| 595 | Sand Hill Global Advisors#595 · 5,885 sh | 5,885 | $2.9M | 0.09% | -7.6% |
| 596 | Mediolanum International Funds Ltd#596 · 5,776 sh | 5,776 | $2.9M | 0.02% | +1.2% |
| 597 | WIMMER ASSOCIATES 1#597 · 5,796 sh | 5,796 | $2.9M | 1.30% | +1.1% |
| 598 | Livforsakringsbolaget Skandia, Omsesidigt#598 · 5,780 sh | 5,780 | $2.9M | — | +207.4% |
| 599 | GKV Capital Management#599 · 5,761 sh | 5,761 | $2.9M | 0.92% | +46.7% |
| 600 | Highview Capital Management#600 · 5,745 sh | 5,745 | $2.9M | 0.82% | +3.1% |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.