What hedge funds are most similar to Siren, L.L.C.?

The funds with the most similar 13F portfolios to Siren, L.L.C. are Logos Global, StemPoint, Avoro Advisors, based on overlapping conviction holdings in the latest SEC filings.

How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to Siren, L.L.C.

13F Portfolio OverlapQ2 2026Siren, L.L.C. portfolio →

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Most similar hedge funds by 13F overlap

Siren, L.L.C. is an institutional investor managing $4.9B across 117 U.S. equity positions as of Q2 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to Siren, L.L.C. are Logos Global, StemPoint, Avoro Advisors, with shared positions in $ERAS, $TNGX, $RVMD, $ABVX, $COGT, $IRON. The full ranking of 25 similar funds is below.

#1Logos Global Management LPActive

Substantial overlap · 13 shared positions

$ERAS $TNGX $RVMD $ABVX $COGT $IRON

$2.3B

68 positions

#2StemPoint Capital LPPassive

Substantial overlap · 10 shared positions

$ERAS $TNGX $RVMD $SRRK $ELVN $SYRE

$581M

84 positions

#3Avoro Capital Advisors LLCSmart money

Substantial overlap · 10 shared positions

$KYMR $RVMD $ARWR $XENE $TSHA $DFTX

$11.1B

26 positions

#4Rock Springs Capital Management LPActive

Notable overlap · 12 shared positions

$RVMD $KYMR $RYTM $SRRK $XENE $ERAS

$2.0B

104 positions

#5First Turn Management, LLCActive

Notable overlap · 11 shared positions

$RVMD $ERAS $RYTM $ELVN $SRRK $XENE

$935M

31 positions

#6Seven Fleet Capital Management LPActive

Notable overlap · 12 shared positions

$TNGX $RVMD $ELVN $MANE $ABVX $TSHA

$606M

96 positions

#7RA CAPITAL MANAGEMENT, L.P.Smart money

Notable overlap · 11 shared positions

$EWTX $RYTM $BCAX $PBLS $ABVX $COAG

$11.5B

84 positions

#8HighVista Strategies LLCPassive

Notable overlap · 12 shared positions

$RVMD $TNGX $ELVN $SYRE $ABVX $COGT

$439M

147 positions

#9BAKER BROS. ADVISORS LPSmart money

Notable overlap · 12 shared positions

$KYMR $RVMD $ONC $RYTM $ARWR $EWTX

$20.0B

84 positions

#10Cormorant Asset Management, LPActive

Notable overlap · 13 shared positions

$ERAS $EWTX $TNGX $PBLS $ABVX $OLMA

$2.0B

50 positions

#11Affinity Asset Advisors, LLCActive

Notable overlap · 10 shared positions

$ERAS $RVMD $SYRE $XENE $ABVX $COGT

$2.2B

113 positions

#12Boxer Capital Management, LLCSmart money

Notable overlap · 9 shared positions

$TNGX $KYMR $RVMD $ABVX $DFTX $SYRE

$1.3B

63 positions

#13BVF INC/ILActive

Notable overlap · 8 shared positions

$KYMR $RVMD $STOK $IRON $OLMA $GPCR

$3.9B

44 positions

#14Redmile Group, LLCSmart money

Notable overlap · 6 shared positions

$SRRK $STOK $COGT $SLDB $XENE $SLN

$1.5B

39 positions

#15Vestal Point Capital, LPActive

Notable overlap · 9 shared positions

$BCAX $ARWR $RVMD $ELVN $ABVX $TSHA

$4.3B

68 positions

#16Paradigm Biocapital Advisors LPActive

Notable overlap · 6 shared positions

$TNGX $RVMD $ERAS $EWTX $SYRE $OLMA

$5.3B

28 positions

#17Integral Health Asset Management, LLCActive

Notable overlap · 8 shared positions

$RVMD $EWTX $RYTM $SRRK $CYTK $TNGX

$2.5B

92 positions

#18SILVERARC CAPITAL MANAGEMENT, LLCActive

Notable overlap · 9 shared positions

$ERAS $RYTM $ELVN $ABVX $COGT $DFTX

$962M

73 positions

#19Patient Square Capital LPActive

Notable overlap · 8 shared positions

$RVMD $ONC $ELVN $XENE $ABVX $RCUS

$646M

23 positions

#20TCG Crossover Management, LLCActive

Notable overlap · 9 shared positions

$TNGX $SYRE $ABVX $RVMD $COGT $RLAY

$4.2B

54 positions

#21DAFNA Capital Management LLCActive

Notable overlap · 10 shared positions

$RVMD $EWTX $BCAX $XENE $RCUS $CYTK

$524M

88 positions

#22PERCEPTIVE ADVISORS LLCActive

Notable overlap · 8 shared positions

$EWTX $RYTM $SYRE $TNGX $RVMD $SLDB

$6.7B

109 positions

#23RTW INVESTMENTS, LPActive

Notable overlap · 9 shared positions

$TNGX $ERAS $SYRE $STOK $CYTK $KLRA

$11.7B

84 positions

#24MPM BioImpact LLCActive

Notable overlap · 9 shared positions

$RVMD $EWTX $ABVX $RLAY $TSHA $STOK

$1.6B

37 positions

#25DIADEMA PARTNERS LPPassive

Notable overlap · 8 shared positions

$RVMD $KYMR $EWTX $ABVX $RCUS $COGT

$791M

149 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.