Healthcare · Nasdaq · AI-powered stock analysis, 32-signal quality score, SEC EDGAR financials, and institutional holdings. Updated .
RHYTHM PHARMACEUTICALS, INC. (RYTM) stock profile, AI quality score, and SEC EDGAR financial data, a Healthcare sector company. 13F Pro's AI-powered ranking engine scores RYTM at 33.9/100 on a 32-signal composite quality model, placing it at rank #2,366 of 2,960 stocks — the bottom half of the AI-ranked universe. RYTM scores in the top quartile across revenue growth (94.6). Areas of concern include balance sheet strength (3.4) and profitability (8.3), which score below median versus the broader universe. Shareholder dilution risk is elevated at 5.6/100, reflecting ongoing share issuance or stock-based compensation. Based on the latest XBRL financial filings (Q2 2026), RHYTHM PHARMACEUTICALS, INC. reports quarterly revenue of $71.3M, net income of $-49.3M, an operating margin of -68.1%. Top institutional holders of RYTM by reported 13-F value include RA CAPITAL MANAGEMENT, L.P., BlackRock, BAKER BROS. ADVISORS, based on the most recent SEC filings. RYTM trades on the Nasdaq exchange and files with the SEC under CIK 1649904. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate RYTM daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for RHYTHM PHARMACEUTICALS, INC. directly from SEC EDGAR.
AI Quality Score
33.9/100
AI Rank
#2,366
Revenue
$71.3M
Net Income
$-49.3M
Operating Margin
-68.1%
| Period | Form | Revenue | Net income | Operating margin |
|---|---|---|---|---|
| FY 2025 | 10-K | $189.8M | $-196.5M | -101.2% |
| FY 2024 | 10-K | $130.1M | $-260.6M | — |
| FY 2023 | 10-K | $77.4M | $-184.7M | — |
| FY 2022 | 10-K | $23.6M | $-181.1M | — |
| FY 2021 | 10-K | $3.2M | $-69.6M | — |
| Institution | Shares | Value | Reported |
|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 6,666,837 | $740.2M | 2026-06-30 |
| BlackRock | 6,156,902 | $683.6M | 2026-06-30 |
| BAKER BROS. ADVISORS | 5,604,483 | $622.3M | 2026-06-30 |
| PRIMECAP MANAGEMENT | 3,168,853 | $351.8M | 2026-06-30 |
| VANGUARD PORTFOLIO MANAGEMENT | 3,136,895 | $348.3M | 2026-06-30 |
| VANGUARD CAPITAL MANAGEMENT | 3,005,977 | $333.8M | 2026-06-30 |
| JPMORGAN CHASE | 2,652,746 | $292.2M | 2026-06-30 |
| PERCEPTIVE ADVISORS | 2,586,295 | $287.2M | 2026-06-30 |
| STATE STREET | 2,573,529 | $285.7M | 2026-06-30 |
| PRICE T ROWE ASSOCIATES | 2,566,171 | $284.9M | 2026-06-30 |
13F Pro Quality Score
Rank #2,366 of 2,960 stocks
Rankings refresh quarterly once 80% of peers have filed (~45 days after quarter-end). Next update: ~Nov 14, 2026.
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