RHYTHM PHARMACEUTICALS, INC.(RYTM)— Stock Profile, AI Score & Financials

Healthcare · Nasdaq · AI-powered stock analysis, 32-signal quality score, SEC EDGAR financials, and institutional holdings. Updated .

RHYTHM PHARMACEUTICALS, INC. (RYTM) stock profile, AI quality score, and SEC EDGAR financial data, a Healthcare sector company. 13F Pro's AI-powered ranking engine scores RYTM at 33.9/100 on a 32-signal composite quality model, placing it at rank #2,366 of 2,960 stocks — the bottom half of the AI-ranked universe. RYTM scores in the top quartile across revenue growth (94.6). Areas of concern include balance sheet strength (3.4) and profitability (8.3), which score below median versus the broader universe. Shareholder dilution risk is elevated at 5.6/100, reflecting ongoing share issuance or stock-based compensation. Based on the latest XBRL financial filings (Q2 2026), RHYTHM PHARMACEUTICALS, INC. reports quarterly revenue of $71.3M, net income of $-49.3M, an operating margin of -68.1%. Top institutional holders of RYTM by reported 13-F value include RA CAPITAL MANAGEMENT, L.P., BlackRock, BAKER BROS. ADVISORS, based on the most recent SEC filings. RYTM trades on the Nasdaq exchange and files with the SEC under CIK 1649904. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate RYTM daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for RHYTHM PHARMACEUTICALS, INC. directly from SEC EDGAR.

AI Quality Score

33.9/100

AI Rank

#2,366

Revenue

$71.3M

Net Income

$-49.3M

Operating Margin

-68.1%

RYTM key financials by period

RHYTHM PHARMACEUTICALS, INC. reported revenue, net income and margins by fiscal period, from SEC filings.
PeriodFormRevenueNet incomeOperating margin
FY 202510-K$189.8M$-196.5M-101.2%
FY 202410-K$130.1M$-260.6M
FY 202310-K$77.4M$-184.7M
FY 202210-K$23.6M$-181.1M
FY 202110-K$3.2M$-69.6M

Institutions holding RYTM

Institutional investors reporting a position in RHYTHM PHARMACEUTICALS, INC. on SEC Form 13F.
InstitutionSharesValueReported
RA CAPITAL MANAGEMENT, L.P.6,666,837$740.2M2026-06-30
BlackRock6,156,902$683.6M2026-06-30
BAKER BROS. ADVISORS5,604,483$622.3M2026-06-30
PRIMECAP MANAGEMENT3,168,853$351.8M2026-06-30
VANGUARD PORTFOLIO MANAGEMENT3,136,895$348.3M2026-06-30
VANGUARD CAPITAL MANAGEMENT3,005,977$333.8M2026-06-30
JPMORGAN CHASE2,652,746$292.2M2026-06-30
PERCEPTIVE ADVISORS2,586,295$287.2M2026-06-30
STATE STREET2,573,529$285.7M2026-06-30
PRICE T ROWE ASSOCIATES2,566,171$284.9M2026-06-30
RYTM

RHYTHM PHARMACEUTICALS, INC.

RYTM
NasdaqMid CapHealthcare

13F Pro Quality Score

33.9/100

Rank #2,366 of 2,960 stocks

View Healthcare peers →

Rankings refresh quarterly once 80% of peers have filed (~45 days after quarter-end). Next update: ~Nov 14, 2026.

Revenue Growth

94.6/100

Profitability

8.3/100

Balance Sheet

3.4/100

Earnings Quality

33.4/100

Free Cash Flow

10.0/100

Institutional Flow

60.6/100

Revenue Scale

26.2/100

Dilution Risk

5.6/100

Price Chart

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Key Metrics

Revenue

Q2 2026
EDGAR

$71.25M

Net Income

Q2 2026
EDGAR

$-49.30M

EPS (Diluted)

Q2 2026
EDGAR

$-0.73

Operating Margin

Q2 2026
EDGAR

-68.1%

Top Institutional Holders

as of Q2 2026
$8.58B total

Financial Trends

Revenue & Net Income

Earnings Per Share

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