BeOne Medicines Ltd.(ONC)Stock Analysis
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Pending next ranking run
This company passes all size and coverage filters but hasn't been included in the latest quarterly ranking run. Rankings refresh on Jan 1, Apr 1, Jul 1, Oct 1.
Financial data, filings, and institutional holdings below are still tracked in full — only the proprietary quality composite is unavailable for this name.
ONC Stock Analysis & AI Quality Score
AI stock analysis and institutional research for BeOne Medicines Ltd. (ONC), a Healthcare sector company. ONC is not currently included in 13F Pro's AI-ranked quality universe — this company passes all size and coverage filters but hasn't been included in the latest quarterly ranking run. rankings refresh on jan 1, apr 1, jul 1, oct 1. Based on the latest XBRL financial filings (Q1 2026), BeOne Medicines Ltd. reports quarterly revenue of $1.5B, net income of $227.4M, free cash flow of $160.5M. Top institutional holders of ONC by reported 13-F value include BAKER BROS. ADVISORS, PRIMECAP MANAGEMENT CO/CA/, Capital International Investors, based on the most recent SEC filings. ONC trades on the Nasdaq exchange and files with the SEC under CIK 1651308. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate ONC daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for BeOne Medicines Ltd. directly from SEC EDGAR.
Revenue
Q1 2026
$1.5B
Net Income
Q1 2026
$227.4M
Free Cash Flow
Q1 2026
$160.5M
ROIC
Q1 2026
4.5%
D/E Ratio
Q1 2026
0.23
Revenue & Net Income
Earnings Per Share
Key Financials Over Time
Export Financial Table · Pro+Revenue
+223.9% YoYNet Income
+55.8% YoYOperating Income
+60.5% YoYEPS (Diluted)
+61.2% YoYTotal Assets
-30.6% YoYTotal Debt
+9.0% YoYOp. Cash Flow
+89.2% YoY| Metric | FY 2024 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|
| Revenue | $3.81B +223.9% | $1.18B +280.8% | $308.9M -27.9% | $428.2M +116.0% | $198.2M -16.8% | $238.4M |
| Net Income | $-644.8M +55.8% | $-1.46B +10.3% | $-1.62B -71.3% | $-948.6M -40.8% | $-673.8M -623.7% | $-93.1M |
| Operating Income | $-568.2M +60.5% | $-1.44B +13.2% | $-1.66B -72.7% | $-959.9M -36.0% | $-705.8M -616.8% | $-98.5M |
| EPS (Diluted) | $-0.47 +61.2% | $-1.21 +19.3% | $-1.50 -23.0% | $-1.22 | — | — |
| Total Assets | $5.92B -30.6% | $8.54B +52.4% | $5.60B +247.4% | $1.61B -28.3% | $2.25B +115.0% | $1.05B |
| Total Debt | $1.87B +9.0% | $1.72B -53.9% | $3.72B +4364.2% | $83.3M +68.3% | $49.5M +168.4% | $18.4M |
| Operating Cash Flow | $-140.6M +89.2% | $-1.30B -1.2% | $-1.28B -71.1% | $-750.3M -37.0% | $-547.7M -4395.1% | $12.8M |
AI Insight: ONC Financial Trends
BeOne inflected to sustained profitability in 2025, with operating income surging from -$120M in Q3 2024 to $250M in Q1 2026 on 51% revenue growth.
• Revenue grew 51% from $1,002M in Q3 2024 to $1,513M in Q1 2026, with eight consecutive quarters of sequential gains.
• Operating income swung from -$120M in Q3 2024 to $250M in Q1 2026, marking a clear and accelerating profitability inflection.
• Operating cash flow turned consistently positive, rising from -$96M in Q2 2024 to $417M in Q4 2025, though it dipped to $201M in Q1 2026.
• Equity expanded from $3,332M in Q4 2024 to $4,760M in Q1 2026, strengthening the balance sheet alongside rising profitability.
⚠ Total debt spiked to $7,431M in Q4 2024 before collapsing to $813M–$1,088M — the spike's nature warrants clarification.
⚠ Net income of $67M in Q4 2025 lagged operating income of $185M, suggesting below-the-line charges worth monitoring.
⚠ Operating cash flow fell to $201M in Q1 2026 from $417M in Q4 2025 — early sign of working-capital pressure or seasonal effect.
AI Insight: ONC Ratio Trends
BeOne Medicines flipped from deeply negative margins to a 16.5% operating margin in Q1 2026, marking a dramatic profitability inflection within four quarters.
• Operating margin surged from -12.0% in Q3 2024 to 16.5% in Q1 2026 — a nearly 29 percentage-point swing in five quarters.
• ROIC turned positive in Q1 2025 at 1.0% and accelerated to 17.1% by Q1 2026, signaling increasingly productive capital deployment.
• Leverage normalized sharply: D/E collapsed from 2.23 in Q4 2024 to 0.23 in Q1 2026, strengthening the balance sheet materially.
• Net profit margin dipped to 4.4% in Q4 2025 versus 8.8% in Q3 2025, before rebounding to 15.0% in Q1 2026 — suggesting Q4 seasonality or one-off items.
⚠ Q4 2025 NPM fell sharply to 4.4% while operating margin held at 12.3% — the below-the-line gap warrants monitoring for recurring non-operating costs.
⚠ TTM ROIC of 11.7% lags the Q1 2026 quarterly read of 17.1%; sustaining the recent improvement across full-year results is unconfirmed.
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Top Institutional Holders of ONC
BAKER BROS. ADVISORS LP
$2.6B8,799,053 shPRIMECAP MANAGEMENT CO/CA/
$1.5B4,975,181 shCapital International Investors
$1.2B4,158,726 shFMR LLC
$1.1B3,693,610 shCapital World Investors
$481.9M1,622,687 shHillhouse Capital Advisors, Ltd.
$307.2M1,034,306 shCITADEL ADVISORS LLC
$306.6M1,032,298 shTemasek Holdings (Private) Ltd
$256.2M862,643 shBlackRock, Inc.
$195.3M657,501 shSiren, L.L.C.
$138.1M465,000 sh
| Fund | Value | Shares |
|---|---|---|
| BAKER BROS. ADVISORS LP | $2.6B | 8,799,053 |
| PRIMECAP MANAGEMENT CO/CA/ | $1.5B | 4,975,181 |
| Capital International Investors | $1.2B | 4,158,726 |
| FMR LLC | $1.1B | 3,693,610 |
| Capital World Investors | $481.9M | 1,622,687 |
| Hillhouse Capital Advisors, Ltd. | $307.2M | 1,034,306 |
| CITADEL ADVISORS LLC | $306.6M | 1,032,298 |
| Temasek Holdings (Private) Ltd | $256.2M | 862,643 |
| BlackRock, Inc. | $195.3M | 657,501 |
| Siren, L.L.C. | $138.1M | 465,000 |
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Popular Research
Is ONC a good stock to buy?
13F Pro's AI-powered analysis of BeOne Medicines Ltd. (ONC) draws on SEC EDGAR-sourced fundamentals, institutional 13F holdings, and insider Form 4 transactions in the Healthcare sector (listed on Nasdaq). The 32-signal AI Quality Score, current rank, and full bull/bear verdict for ONC are available on the ONC stock profile dashboard — with the same data, AI insights, ratios, and institutional activity refreshed after every 10-K, 10-Q, 13F, and Form 4 filing.
Which hedge funds own ONC?
Institutional investors are required to disclose their holdings quarterly via SEC Form 13F. 13F Pro aggregates these filings to show which hedge funds, mutual funds, and asset managers are buying or selling ONC. Combined with insider transaction data from Form 4 filings and AI-powered analysis from 10 specialized research agents, 13F Pro provides a comprehensive view of BeOne Medicines Ltd.'s investment landscape.