What hedge funds are most similar to Siren, L.L.C.?

The funds with the most similar 13F portfolios to Siren, L.L.C. are Logos Global, StemPoint, Redmile Group,, based on overlapping conviction holdings in the latest SEC filings.

How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to Siren, L.L.C.

13F Portfolio OverlapQ1 2026Siren, L.L.C. portfolio →

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Most similar hedge funds by 13F overlap

Siren, L.L.C. is an institutional investor managing $3.6B across 100 U.S. equity positions as of Q1 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to Siren, L.L.C. are Logos Global, StemPoint, Redmile Group,, with shared positions in $ERAS, $TNGX, $RVMD, $OLMA, $IRON, $RYTM. The full ranking of 25 similar funds is below.

#1Logos Global Management LPActive

Substantial overlap · 14 shared positions

$ERAS $TNGX $RVMD $OLMA $IRON $RYTM

$2.0B

66 positions

#2StemPoint Capital LPActive

Substantial overlap · 12 shared positions

$SRRK $RVMD $EWTX $GPCR $XENE $SYRE

$515M

82 positions

#3Redmile Group, LLCSmart money

Substantial overlap · 8 shared positions

$SRRK $STOK $COGT $XENE $SLDB $DBVT

$1.5B

35 positions

#4Paradigm Biocapital Advisors LPActive

Substantial overlap · 12 shared positions

$EWTX $ERAS $RVMD $OLMA $TNGX $SRRK

$4.9B

35 positions

#5BVF INC/ILActive

Substantial overlap · 9 shared positions

$KYMR $RVMD $OLMA $STOK $GPCR $IRON

$3.1B

41 positions

#6Vestal Point Capital, LPActive

Notable overlap · 13 shared positions

$BCAX $RVMD $ARWR $SRRK $COGT $IRON

$3.6B

90 positions

#7Avoro Capital Advisors LLCActive

Notable overlap · 10 shared positions

$KYMR $ARWR $RVMD $XENE $GPCR $CNTA

$10.2B

32 positions

#8First Turn Management, LLCActive

Notable overlap · 11 shared positions

$RVMD $SRRK $KYMR $XENE $COGT $ERAS

$895M

33 positions

#9Rock Springs Capital Management LPActive

Notable overlap · 11 shared positions

$RVMD $KYMR $SRRK $XENE $GPCR $RYTM

$1.7B

100 positions

#10KVP Capital Advisors, LPActive

Notable overlap · 8 shared positions

$ERAS $TNGX $EWTX $RVMD $IRON $SRRK

$134M

32 positions

#11MPM BioImpact LLCActive

Notable overlap · 11 shared positions

$EWTX $RVMD $XENE $STOK $CYTK $DYN

$1.3B

41 positions

#12BAKER BROS. ADVISORS LPSmart money

Notable overlap · 13 shared positions

$KYMR $ONC $RVMD $RYTM $EWTX $ARWR

$17.4B

84 positions

#13Samsara BioCapital, LLCSmart money

Notable overlap · 3 shared positions

$SRRK $SEPN $PVLA

$1.0B

22 positions

#14SILVERARC CAPITAL MANAGEMENT, LLCActive

Notable overlap · 11 shared positions

$ERAS $SRRK $COGT $RYTM $IRON $XENE

$980M

73 positions

#15Cormorant Asset Management, LPActive

Notable overlap · 11 shared positions

$ERAS $EWTX $OLMA $TNGX $CNTA $DMRA

$2.0B

47 positions

#16Vivo Capital, LLCActive

Notable overlap · 9 shared positions

$ERAS $TNGX $MANE $COGT $DYN $DBVT

$1.2B

45 positions

#17Affinity Asset Advisors, LLCActive

Notable overlap · 11 shared positions

$ERAS $XENE $COGT $CNTA $SYRE $CYTK

$1.9B

105 positions

#18Seven Fleet Capital Management LPActive

Notable overlap · 8 shared positions

$TNGX $RVMD $ERAS $COGT $CYTK $TSHA

$315M

114 positions

#19Commodore Capital LPActive

Notable overlap · 8 shared positions

$KYMR $ERAS $XENE $COGT $SYRE $ELVN

$1.7B

36 positions

#20VR Adviser, LLCSmart money

Notable overlap · 10 shared positions

$ERAS $COGT $SYRE $DYN $ORIC $ENGN

$2.7B

33 positions

#21Bellevue Group AGActive

Notable overlap · 8 shared positions

$SRRK $RVMD $CRNX $TNGX $EWTX $ELVN

$4.2B

155 positions

#22Octagon Capital Advisors LPActive

Notable overlap · 8 shared positions

$KYMR $XENE $COGT $IRON $CNTA $TSHA

$904M

29 positions

#23RA CAPITAL MANAGEMENT, L.P.Smart money

Notable overlap · 10 shared positions

$EWTX $RYTM $IRON $BCAX $SEPN $TSHA

$9.4B

85 positions

#24DAFNA Capital Management LLCActive

Notable overlap · 9 shared positions

$RVMD $XENE $BCAX $RCUS $CYTK $STOK

$440M

83 positions

#25Boxer Capital Management, LLCSmart money

Notable overlap · 7 shared positions

$KYMR $TNGX $RVMD $COGT $CYTK $ZURA

$762M

54 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.