IONIS PHARMACEUTICALS INC (IONS) — Institutional Holders, Q2 2026 (page 2)
533 institutional investment managers reported a IONS position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $15.2B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 101 to 200. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
IONS 13F holders ranked 101–200 of 533
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 101 | SECTOR GAMMA AS#101 · 189,468 sh | 189,468 | $15.0M | 3.26% | +11.8% |
| 102 | Polymer Capital Management (HK) LTD#102 · 177,897 sh | 177,897 | $14.1M | 0.71% | +190.7% |
| 103 | STATE OF WISCONSIN INVESTMENT BOARD#103 · 4,094,492 sh | 4,094,492 | $13.7M | 0.03% | +32.2% |
| 104 | DEUTSCHE BANK AG\#104 · 169,614 sh | 169,614 | $13.4M | <0.01% | +6.1% |
| 105 | ADAR1 Capital Management#105 · 166,286 sh | 166,286 | $13.2M | 0.60% | +3.7% |
| 106 | RHUMBLINE ADVISERS#106 · 164,911 sh | 164,911 | $13.1M | <0.01% | -4.9% |
| 107 | Sicart Associates#107 · 160,694 sh | 160,694 | $12.7M | 3.12% | +0.8% |
| 108 | HRT FINANCIAL#108 · 186,798 sh | 186,798 | $12.4M | 0.03% | -25.9% |
| 109 | VANGUARD ASSET MANAGEMENT, Ltd#109 · 155,088 sh | 155,088 | $12.3M | <0.01% | +12.8% |
| 110 | CSS#110 · 152,289 sh | 152,289 | $12.1M | 0.47% | +92.5% |
| 111 | DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt#111 · 151,301 sh | 151,301 | $12.0M | <0.01% | -9.8% |
| 112 | ADAGE CAPITAL PARTNERS GP, L.L.C.#112 · 150,000 sh | 150,000 | $11.9M | 0.02% | +200.0% |
| 113 | M&G Plc#113 · 7,334,090 sh | 7,334,090 | $11.7M | 0.06% | -0.2% |
| 114 | Hudson Bay Capital Management#114 · 145,000 sh | 145,000 | $11.5M | 0.03% | -50.9% |
| 115 | Artia Global Partners#115 · 144,376 sh | 144,376 | $11.4M | 2.11% | 0.0% |
| 116 | Fisher Asset Management#116 · 137,184 sh | 137,184 | $10.9M | <0.01% | -3.1% |
| 117 | HealthInvest Partners AB#117 · 137,131 sh | 137,131 | $10.9M | 2.93% | +392.0% |
| 118 | LAZARD ASSET MANAGEMENT#118 · 13,294,480 sh | 13,294,480 | $10.7M | 0.02% | -19.7% |
| 119 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM#119 · 131,818 sh | 131,818 | $10.5M | 0.02% | -3.0% |
| 120 | LORD, ABBETT#120 · 6,592,000 sh | 6,592,000 | $10.2M | 0.03% | -6.7% |
| 121 | SEI INVESTMENTS#121 · 127,868 sh | 127,868 | $10.1M | <0.01% | -51.2% |
| 122 | EFG International AG#122 · 122,804 sh | 122,804 | $9.7M | 0.18% | +30.7% |
| 123 | Gotham Asset Management#123 · 121,252 sh | 121,252 | $9.6M | 0.02% | +22.5% |
| 124 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#124 · 120,678 sh | 120,678 | $9.6M | <0.01% | -19.3% |
| 125 | BRAIDWELL#125 · 116,762 sh | 116,762 | $9.3M | 0.34% | -10.8% |
| 126 | NORGES BANK#126 · 114,359 sh | 114,359 | $9.1M | <0.01% | — |
| 127 | SEB Asset Management AB#127 · 114,334 sh | 114,334 | $9.1M | 0.03% | 0.0% |
| 128 | EDMOND DE ROTHSCHILD HOLDING S.A.#128 · 113,320 sh | 113,320 | $9.0M | 0.12% | -17.4% |
| 129 | Squarepoint Ops#129 · 109,379 sh | 109,379 | $8.7M | <0.01% | -84.3% |
| 130 | KENNEDY CAPITAL MANAGEMENT#130 · 106,342 sh | 106,342 | $8.4M | 0.15% | -4.9% |
| 131 | ADVENT CAPITAL MANAGEMENT#131 · 5,146,000 sh | 5,146,000 | $8.0M | 0.18% | +0.3% |
| 132 | ENVESTNET ASSET MANAGEMENT#132 · 98,124 sh | 98,124 | $7.8M | <0.01% | +5.1% |
| 133 | PICTON MAHONEY ASSET MANAGEMENT#133 · 5,000,000 sh | 5,000,000 | $7.8M | 0.06% | New |
| 134 | TFG Asset Management GP Ltd#134 · 97,173 sh | 97,173 | $7.7M | 1.21% | +132.7% |
| 135 | Swedbank AB#135 · 95,666 sh | 95,666 | $7.6M | — | +196.6% |
| 136 | PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO#136 · 90,589 sh | 90,589 | $7.2M | 0.02% | +481.1% |
| 137 | CITIGROUP#137 · 275,746 sh | 275,746 | $7.2M | <0.01% | +88.2% |
| 138 | CenterBook Partners#138 · 89,280 sh | 89,280 | $7.1M | 0.35% | -40.8% |
| 139 | Exome Asset Management#139 · 88,177 sh | 88,177 | $7.0M | 4.31% | -19.9% |
| 140 | Amundi#140 · 3,470,190 sh | 3,470,190 | $7.0M | <0.01% | -0.1% |
| 141 | DekaBank Deutsche Girozentrale#141 · 93,807 sh | 93,807 | $6.8M | — | 0.0% |
| 142 | DIMENSIONAL FUND ADVISORS#142 · 84,748 sh | 84,748 | $6.7M | <0.01% | -68.3% |
| 143 | Russell Investments Group, Ltd.#143 · 81,319 sh | 81,319 | $6.4M | <0.01% | +29.2% |
| 144 | FRED ALGER MANAGEMENT#144 · 78,932 sh | 78,932 | $6.3M | 0.02% | +177.4% |
| 145 | China Universal Asset Management , Ltd.#145 · 76,302 sh | 76,302 | $6.0M | 0.36% | -1.3% |
| 146 | Police & Firemen's Retirement System of New Jersey#146 · 75,061 sh | 75,061 | $6.0M | 0.04% | +11.5% |
| 147 | SG Americas Securities#147 · 74,589 sh | 74,589 | $5.9M | <0.01% | +17.8% |
| 148 | Erste Asset Management GmbH#148 · 71,800 sh | 71,800 | $5.8M | 0.04% | 0.0% |
| 149 | Future Fund#149 · 71,362 sh | 71,362 | $5.7M | 1.62% | +21.5% |
| 150 | Hillsdale Investment Management#150 · 70,900 sh | 70,900 | $5.6M | 0.13% | 0.0% |
| 151 | Treasurer of the State of North Carolina#151 · 70,021 sh | 70,021 | $5.6M | 0.01% | +3.4% |
| 152 | BANK OF NOVA SCOTIA#152 · 68,548 sh | 68,548 | $5.4M | <0.01% | New |
| 153 | Jupiter Topco#153 · 68,191 sh | 68,191 | $5.4M | <0.01% | — |
| 154 | AMERIPRISE FINANCIAL#154 · 67,705 sh | 67,705 | $5.4M | <0.01% | -89.7% |
| 155 | Y-Intercept (Hong Kong) Ltd#155 · 67,374 sh | 67,374 | $5.3M | — | New |
| 156 | GREAT LAKES ADVISORS#156 · 66,924 sh | 66,924 | $5.3M | 0.04% | -43.7% |
| 157 | VICTORY CAPITAL MANAGEMENT#157 · 65,967 sh | 65,967 | $5.2M | <0.01% | -39.3% |
| 158 | Vanguard Global Advisers#158 · 65,858 sh | 65,858 | $5.2M | <0.01% | -8.4% |
| 159 | Zurcher Kantonalbank (Zurich Cantonalbank)#159 · 65,077 sh | 65,077 | $5.2M | <0.01% | +8.0% |
| 160 | Quantinno Capital Management#160 · 64,914 sh | 64,914 | $5.1M | <0.01% | +17.0% |
| 161 | VAN ECK ASSOCIATES#161 · 63,396 sh | 63,396 | $5.0M | <0.01% | +83.7% |
| 162 | THRIVENT FINANCIAL FOR LUTHERANS#162 · 62,743 sh | 62,743 | $5.0M | <0.01% | +529.8% |
| 163 | PANAGORA ASSET MANAGEMENT#163 · 61,125 sh | 61,125 | $4.8M | 0.01% | +6.4% |
| 164 | Stanley-Laman Group, Ltd.#164 · 60,842 sh | 60,842 | $4.8M | — | +54.8% |
| 165 | XTX Topco Ltd#165 · 60,776 sh | 60,776 | $4.8M | 0.06% | -24.5% |
| 166 | SCHRODER INVESTMENT MANAGEMENT GROUP#166 · 58,865 sh | 58,865 | $4.7M | <0.01% | New |
| 167 | Rhenman & Partners Asset Management AB#167 · 59,900 sh | 59,900 | $4.7M | 0.45% | -35.5% |
| 168 | Sovran Advisors#168 · 84,984 sh | 84,984 | $4.7M | 0.35% | New |
| 169 | Edgestream Partners, L.P.#169 · 56,715 sh | 56,715 | $4.5M | 0.13% | -17.0% |
| 170 | One Capital Management#170 · 58,939 sh | 58,939 | $4.4M | 0.12% | 0.0% |
| 171 | FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A.#171 · 53,795 sh | 53,795 | $4.3M | — | -0.9% |
| 172 | NICOLA WEALTH MANAGEMENT LTD.#172 · 52,000 sh | 52,000 | $4.1M | 0.47% | 0.0% |
| 173 | KBC Group NV#173 · 51,127 sh | 51,127 | $4.1M | — | +69.2% |
| 174 | State of New Jersey Common Pension Fund D#174 · 50,743 sh | 50,743 | $4.0M | 0.01% | -3.5% |
| 175 | Creative Planning#175 · 50,554 sh | 50,554 | $4.0M | <0.01% | -3.2% |
| 176 | Campbell & Investment Adviser#176 · 49,632 sh | 49,632 | $3.9M | 0.21% | +1500.5% |
| 177 | CAPITAL COUNSEL#177 · 49,580 sh | 49,580 | $3.9M | 0.15% | 0.0% |
| 178 | Toroso Investments#178 · 49,178 sh | 49,178 | $3.9M | <0.01% | +42.8% |
| 179 | WORLDQUANT MILLENNIUM ADVISORS#179 · 48,976 sh | 48,976 | $3.9M | 0.01% | +75.4% |
| 180 | JONES FINANCIAL COMPANIES LLLP#180 · 47,442 sh | 47,442 | $3.9M | <0.01% | +77.5% |
| 181 | Sumitomo Mitsui#181 · 47,836 sh | 47,836 | $3.8M | <0.01% | -41.6% |
| 182 | Nikko Asset Management Americas#182 · 47,656 sh | 47,656 | $3.8M | 0.05% | -41.7% |
| 183 | MACKAY SHIELDS#183 · 2,414,000 sh | 2,414,000 | $3.8M | — | -76.8% |
| 184 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO#184 · 46,862 sh | 46,862 | $3.7M | 0.01% | +1.8% |
| 185 | Coppell Advisory Solutions#185 · 26 sh | 26 | $3.7M | 0.30% | New |
| 186 | Calamos Advisors#186 · 876,358 sh | 876,358 | $3.6M | 0.01% | -93.4% |
| 187 | SSI INVESTMENT MANAGEMENT#187 · 2,340,000 sh | 2,340,000 | $3.6M | 0.21% | 0.0% |
| 188 | NATIXIS ADVISORS#188 · 44,728 sh | 44,728 | $3.5M | <0.01% | +88.6% |
| 189 | Arizona State Retirement System#189 · 43,302 sh | 43,302 | $3.4M | 0.02% | +2.5% |
| 190 | Aquatic Capital Management#190 · 42,581 sh | 42,581 | $3.4M | 0.12% | -71.1% |
| 191 | WEST MICHIGAN ADVISORS#191 · 44,614 sh | 44,614 | $3.4M | 0.74% | 0.0% |
| 192 | GUGGENHEIM CAPITAL#192 · 41,405 sh | 41,405 | $3.3M | 0.02% | -6.0% |
| 193 | Assenagon Asset Management S.A.#193 · 40,927 sh | 40,927 | $3.2M | — | +21.5% |
| 194 | J. Goldman#194 · 40,366 sh | 40,366 | $3.2M | 0.08% | -82.8% |
| 195 | LEUCADIA NATIONAL#195 · 38,665 sh | 38,665 | $3.1M | 0.02% | -96.0% |
| 196 | EXCHANGE TRADED CONCEPTS#196 · 38,627 sh | 38,627 | $3.1M | 0.01% | +13.8% |
| 197 | Vanguard Investments Australia, Ltd.#197 · 38,557 sh | 38,557 | $3.1M | <0.01% | 0.0% |
| 198 | STRS OHIO#198 · 38,166 sh | 38,166 | $3.0M | 0.01% | +32.6% |
| 199 | Rafferty Asset Management#199 · 37,648 sh | 37,648 | $3.0M | <0.01% | -37.6% |
| 200 | DCF Advisers#200 · 37,500 sh | 37,500 | $3.0M | 0.53% | -33.0% |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.