IONIS PHARMACEUTICALS INC (IONS) — Institutional Holders, Q2 2026 (page 4)
533 institutional investment managers reported a IONS position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $15.2B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 301 to 400. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
IONS 13F holders ranked 301–400 of 533
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 301 | SECTORAL ASSET MANAGEMENT#301 · 7,200 sh | 7,200 | $570.9K | 0.40% | 0.0% |
| 302 | O'SHAUGHNESSY ASSET MANAGEMENT#302 · 7,166 sh | 7,166 | $568.2K | <0.01% | -6.8% |
| 303 | Callan Family Office#303 · 7,143 sh | 7,143 | $566.4K | 0.01% | +0.9% |
| 304 | SILVERCREST ASSET MANAGEMENT GROUP#304 · 7,055 sh | 7,055 | $559.4K | <0.01% | 0.0% |
| 305 | MERCER GLOBAL ADVISORS#305 · 6,918 sh | 6,918 | $548.4K | <0.01% | +9.9% |
| 306 | PSP Research#306 · 6,800 sh | 6,800 | $539.2K | — | 0.0% |
| 307 | J. Safra Sarasin Holding AG#307 · 6,751 sh | 6,751 | $535.3K | — | +5.0% |
| 308 | Significant Wealth Partners#308 · 6,613 sh | 6,613 | $524.3K | 0.57% | -0.8% |
| 309 | GROUP ONE TRADING, L.P.#309 · 6,493 sh | 6,493 | $514.8K | <0.01% | +243.2% |
| 310 | US BANCORP \DE\#310 · 6,366 sh | 6,366 | $504.8K | <0.01% | +26.1% |
| 311 | PRAXIS INVESTMENT MANAGEMENT#311 · 6,232 sh | 6,232 | $494.0K | 0.03% | 0.0% |
| 312 | Nykredit A/S#312 · 6,154 sh | 6,154 | $488.0K | <0.01% | — |
| 313 | Janney Montgomery Scott#313 · 6,138 sh | 6,138 | $487.0K | <0.01% | New |
| 314 | MCF Advisors#314 · 6,136 sh | 6,136 | $486.5K | 0.02% | New |
| 315 | Cypress Capital#315 · 6,000 sh | 6,000 | $475.7K | — | 0.0% |
| 316 | Cerity Partners#316 · 5,989 sh | 5,989 | $474.9K | <0.01% | -21.2% |
| 317 | Frank, Rimerman Advisors#317 · 5,807 sh | 5,807 | $460.4K | — | +0.4% |
| 318 | REGIONS FINANCIAL#318 · 5,604 sh | 5,604 | $444.3K | <0.01% | -8.5% |
| 319 | Robeco Institutional Asset Management B.V.#319 · 5,578 sh | 5,578 | $442.3K | — | -1.4% |
| 320 | E Fund Management , Ltd.#320 · 5,569 sh | 5,569 | $441.6K | <0.01% | -88.1% |
| 321 | TEMA ETFS#321 · 5,525 sh | 5,525 | $438.1K | — | -2.6% |
| 322 | ProShare Advisors#322 · 5,417 sh | 5,417 | $429.5K | <0.01% | -26.7% |
| 323 | VARCOV#323 · 5,390 sh | 5,390 | $427.4K | 0.16% | New |
| 324 | ODDO BHF ASSET MANAGEMENT SAS#324 · 274 sh | 274 | $426.8K | 0.02% | -26.7% |
| 325 | COLDSTREAM CAPITAL MANAGEMENT#325 · 5,352 sh | 5,352 | $424.4K | <0.01% | -5.3% |
| 326 | OneDigital Investment Advisors#326 · 5,345 sh | 5,345 | $423.8K | <0.01% | -0.8% |
| 327 | R Squared Ltd#327 · 5,313 sh | 5,313 | $421.3K | 0.22% | +21.9% |
| 328 | CAPTRUST FINANCIAL ADVISORS#328 · 5,030 sh | 5,030 | $398.8K | <0.01% | +0.6% |
| 329 | Granite Investment Partners#329 · 5,026 sh | 5,026 | $398.5K | 0.02% | -6.0% |
| 330 | CIBC Asset Management#330 · 5,017 sh | 5,017 | $397.8K | <0.01% | 0.0% |
| 331 | Moisand Fitzgerald Tamayo#331 · 5,000 sh | 5,000 | $396.4K | — | 0.0% |
| 332 | AlphaCore Capital#332 · 4,986 sh | 4,986 | $395.3K | <0.01% | +80.5% |
| 333 | Vontobel Holding Ltd.#333 · 4,957 sh | 4,957 | $393.0K | — | -5.4% |
| 334 | Wedmont Private Capital#334 · 6,723 sh | 6,723 | $391.6K | — | +2.4% |
| 335 | NewEdge Advisors#335 · 4,822 sh | 4,822 | $382.3K | <0.01% | -71.6% |
| 336 | Quantbot Technologies#336 · 4,812 sh | 4,812 | $381.5K | 0.01% | New |
| 337 | AZZAD ASSET MANAGEMENT#337 · 4,784 sh | 4,784 | $379.3K | 0.03% | New |
| 338 | North Dakota State Investment Board#338 · 4,703 sh | 4,703 | $372.9K | 0.02% | +1.7% |
| 339 | Atria Investments#339 · 4,690 sh | 4,690 | $371.9K | — | -10.3% |
| 340 | GATEWAY INVESTMENT ADVISERS#340 · 4,630 sh | 4,630 | $367.1K | — | New |
| 341 | MIRAE ASSET GLOBAL ETFS Ltd.#341 · 4,373 sh | 4,373 | $352.9K | <0.01% | +2.3% |
| 342 | Blueshift Asset Management#342 · 4,433 sh | 4,433 | $351.5K | 0.08% | +59.6% |
| 343 | CREDIT AGRICOLE S A#343 · 4,410 sh | 4,410 | $349.7K | <0.01% | 0.0% |
| 344 | Yorktown Management & Research#344 · 4,400 sh | 4,400 | $348.9K | 0.21% | New |
| 345 | Kestra Advisory Services#345 · 4,384 sh | 4,384 | $347.6K | <0.01% | +0.3% |
| 346 | INTRUST BANK NA#346 · 4,339 sh | 4,339 | $344.0K | 0.03% | +7.0% |
| 347 | Checchi Capital Advisers#347 · 4,308 sh | 4,308 | $341.6K | 0.02% | -2.7% |
| 348 | WESTFIELD CAPITAL MANAGEMENT#348 · 4,233 sh | 4,233 | $335.6K | <0.01% | +20.9% |
| 349 | Prospera Financial Services#349 · 4,194 sh | 4,194 | $332.5K | <0.01% | -3.4% |
| 350 | HighTower Advisors#350 · 4,084 sh | 4,084 | $323.8K | <0.01% | +7.6% |
| 351 | WEALTH ENHANCEMENT ADVISORY SERVICES#351 · 5,394 sh | 5,394 | $314.2K | — | +30.8% |
| 352 | Prime Capital Investment Advisors#352 · 3,938 sh | 3,938 | $312.2K | — | -0.8% |
| 353 | Sanctuary Advisors#353 · 3,938 sh | 3,938 | $312.2K | <0.01% | +0.5% |
| 354 | Susquehanna Portfolio Strategies#354 · 3,935 sh | 3,935 | $312.0K | <0.01% | -95.9% |
| 355 | Qsemble Capital Management#355 · 3,887 sh | 3,887 | $308.2K | 0.04% | -84.9% |
| 356 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#356 · 3,839 sh | 3,839 | $304.4K | 0.00% | -68.9% |
| 357 | Rockefeller Capital Management L.P.#357 · 3,832 sh | 3,832 | $303.8K | <0.01% | -7.8% |
| 358 | Pinnacle Wealth Planning Services#358 · 3,780 sh | 3,780 | $299.7K | 0.03% | -10.3% |
| 359 | Bridgefront Capital#359 · 3,778 sh | 3,778 | $299.6K | 0.08% | New |
| 360 | ANB BANK#360 · 3,733 sh | 3,733 | $296.0K | — | -1.0% |
| 361 | Eurizon Capital SGR S.p.A.#361 · 3,639 sh | 3,639 | $293.9K | <0.01% | +3.6% |
| 362 | PARK AVENUE SECURITIES#362 · 3,677 sh | 3,677 | $292.0K | — | New |
| 363 | BERKSHIRE ASSET MANAGEMENT#363 · 3,630 sh | 3,630 | $287.8K | 0.01% | -0.2% |
| 364 | Crossmark Global#364 · 3,615 sh | 3,615 | $286.6K | — | +13.0% |
| 365 | MML INVESTORS SERVICES#365 · 3,600 sh | 3,600 | $285.4K | <0.01% | +13.5% |
| 366 | Sequoia Financial Advisors#366 · 3,567 sh | 3,567 | $282.8K | <0.01% | New |
| 367 | Everhart Financial Group#367 · 3,503 sh | 3,503 | $277.8K | — | +1.0% |
| 368 | GF FUND MANAGEMENT LTD.#368 · 3,497 sh | 3,497 | $277.3K | — | -3.8% |
| 369 | Perigon Wealth Management#369 · 3,477 sh | 3,477 | $275.7K | — | +1.4% |
| 370 | NEW YORK LIFE INVESTMENT MANAGEMENT#370 · 3,458 sh | 3,458 | $274.2K | <0.01% | +28.6% |
| 371 | Victrix Investment Advisors#371 · 3,400 sh | 3,400 | $269.6K | — | New |
| 372 | MITCHELL & PAHL PRIVATE WEALTH#372 · 3,261 sh | 3,261 | $258.6K | — | 0.0% |
| 373 | NWAM#373 · 3,238 sh | 3,238 | $256.7K | 0.01% | 0.0% |
| 374 | Raab & Moskowitz Asset Management#374 · 3,115 sh | 3,115 | $247.0K | 0.05% | 0.0% |
| 375 | QRG CAPITAL MANAGEMENT#375 · 3,079 sh | 3,079 | $244.1K | <0.01% | -0.5% |
| 376 | Venturi Wealth Management#376 · 3,061 sh | 3,061 | $242.7K | <0.01% | 0.0% |
| 377 | HB Wealth Management#377 · 3,025 sh | 3,025 | $239.9K | — | +3.4% |
| 378 | Argent#378 · 3,018 sh | 3,018 | $239.3K | <0.01% | 0.0% |
| 379 | Larson Financial Group#379 · 3,000 sh | 3,000 | $237.9K | <0.01% | -1.0% |
| 380 | Calamos Wealth Management#380 · 151,000 sh | 151,000 | $234.5K | <0.01% | +2.0% |
| 381 | B. Riley Wealth Advisors#381 · 2,897 sh | 2,897 | $233.8K | — | -1.6% |
| 382 | AlphaGrep UK Ltd#382 · 2,946 sh | 2,946 | $233.6K | 0.07% | New |
| 383 | Integrated Wealth Concepts#383 · 2,926 sh | 2,926 | $232.0K | <0.01% | +7.4% |
| 384 | UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT#384 · 2,923 sh | 2,923 | $231.8K | 0.03% | New |
| 385 | Cambria Investment Management, L.P.#385 · 2,885 sh | 2,885 | $228.8K | 0.01% | 0.0% |
| 386 | Voleon Capital Management#386 · 2,862 sh | 2,862 | $226.9K | <0.01% | -87.6% |
| 387 | Montis Financial#387 · 2,700 sh | 2,700 | $214.1K | 0.04% | 0.0% |
| 388 | NORDEN GROUP#388 · 2,685 sh | 2,685 | $212.9K | — | -7.1% |
| 389 | IFG Advisory#389 · 2,678 sh | 2,678 | $212.3K | <0.01% | New |
| 390 | KOM Wealth Management Group#390 · 2,654 sh | 2,654 | $210.4K | — | New |
| 391 | Mitsubishi UFJ Asset Management , Ltd.#391 · 2,618 sh | 2,618 | $207.6K | <0.01% | -2.8% |
| 392 | Mesirow Financial Investment Management#392 · 2,530 sh | 2,530 | $200.6K | <0.01% | -53.7% |
| 393 | Steward Partners Investment Advisory#393 · 2,355 sh | 2,355 | $186.7K | <0.01% | -58.2% |
| 394 | Global Retirement Partners#394 · 2,282 sh | 2,282 | $180.9K | <0.01% | — |
| 395 | Ancora Advisors#395 · 2,215 sh | 2,215 | $175.6K | <0.01% | -7.4% |
| 396 | GAMMA Investing#396 · 2,168 sh | 2,168 | $171.9K | — | +22.8% |
| 397 | State of Wyoming#397 · 2,024 sh | 2,024 | $160.5K | 0.02% | New |
| 398 | Ares Systematic Credit Ltd#398 · 100,000 sh | 100,000 | $155.8K | 0.09% | -80.0% |
| 399 | SIGNATUREFD#399 · 1,880 sh | 1,880 | $149.1K | — | -9.5% |
| 400 | Caption Management#400 · 1,759 sh | 1,759 | $139.5K | <0.01% | -88.7% |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.