What hedge funds are most similar to Rock Springs Capital Management LP?

The funds with the most similar 13F portfolios to Rock Springs Capital Management LP are First Turn, BAKER BROS. ADVISORS, Integral Health Asset, based on overlapping conviction holdings in the latest SEC filings.

How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to Rock Springs

13F Portfolio OverlapQ2 2026Rock Springs portfolio →

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Most similar hedge funds by 13F overlap

Rock Springs Capital Management LP is an institutional investor managing $2.0B across 104 U.S. equity positions as of Q2 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to Rock Springs are First Turn, BAKER BROS. ADVISORS, Integral Health Asset, with shared positions in $RVMD, $MIRM, $XENE, $INSM, $RYTM, $SRRK. The full ranking of 25 similar funds is below.

#1First Turn Management, LLCActive

Substantial overlap · 12 shared positions

$RVMD $MIRM $XENE $INSM $RYTM $SRRK

$935M

31 positions

#2BAKER BROS. ADVISORS LPSmart money

Substantial overlap · 9 shared positions

$RVMD $MDGL $RYTM $KYMR $INSM $GPCR

$20.0B

84 positions

#3Integral Health Asset Management, LLCActive

Substantial overlap · 10 shared positions

$RVMD $RYTM $INSM $SRRK $THC $BSX

$2.5B

92 positions

#4Patient Square Capital LPActive

Substantial overlap · 8 shared positions

$RVMD $MIRM $ARGX $XENE $ELVN $PHVS

$646M

23 positions

#5Avoro Capital Advisors LLCSmart money

Substantial overlap · 9 shared positions

$MDGL $RVMD $KYMR $ARGX $XENE $GPCR

$11.1B

26 positions

#6Siren, L.L.C.Active

Notable overlap · 12 shared positions

$RVMD $KYMR $RYTM $SRRK $XENE $ERAS

$4.9B

117 positions

#7Bellevue Group AGActive

Notable overlap · 12 shared positions

$RVMD $ARGX $SRRK $INSM $ISRG $RARE

$4.8B

148 positions

#8Artia Global Partners LPActive

Notable overlap · 9 shared positions

$RVMD $TVTX $ARGX $INSM $SRRK $NAMS

$542M

48 positions

#9RTW INVESTMENTS, LPActive

Notable overlap · 11 shared positions

$MDGL $ARGX $INSM $RARE $IRTC $ERAS

$11.7B

84 positions

#10BVF INC/ILActive

Notable overlap · 4 shared positions

$RVMD $MIRM $KYMR $GPCR

$3.9B

44 positions

#11Checkpoint Capital L.P.Active

Notable overlap · 4 shared positions

$RVMD $RYTM $ARGX $CYTK

$390M

6 positions

#12DAFNA Capital Management LLCActive

Notable overlap · 8 shared positions

$RVMD $XENE $NBIX $DXCM $CYTK $KYMR

$524M

88 positions

#13Seven Fleet Capital Management LPActive

Notable overlap · 12 shared positions

$RVMD $MIRM $ELVN $PHVS $COGT $ERAS

$606M

96 positions

#14Tri Locum Partners LPActive

Notable overlap · 8 shared positions

$MDGL $RVMD $ARGX $ISRG $ELVN $DXCM

$813M

19 positions

#15Paradigm Biocapital Advisors LPActive

Notable overlap · 6 shared positions

$RVMD $INSM $ERAS $ALNY $TARS $MBX

$5.3B

28 positions

#16HealthInvest Partners ABActive

Notable overlap · 9 shared positions

$RVMD $MIRM $INSM $IRTC $ISRG $NBIX

$372M

39 positions

#17Eagle Health Investments LPActive

Notable overlap · 8 shared positions

$RVMD $KYMR $ARGX $SRRK $INSM $RARE

$603M

27 positions

#18Palo Alto Investors LPActive

Notable overlap · 11 shared positions

$MIRM $INSM $RARE $TVTX $CLDX $ACRS

$724M

52 positions

#19PSP Research LLCActive

Notable overlap · 12 shared positions

$ARGX $KYMR $RARE $CLDX $NBIX $ELVN

$188M

75 positions

#20Casdin Capital, LLCSmart money

Notable overlap · 4 shared positions

$RVMD $SRRK $GPCR $ALNY

$2.0B

43 positions

#21Logos Global Management LPActive

Notable overlap · 9 shared positions

$RVMD $CLDX $ERAS $XENE $GPCR $DYN

$2.3B

68 positions

#22DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)Active

Notable overlap · 8 shared positions

$RVMD $XENE $PHVS $COGT $NAMS $VERA

$9.6B

82 positions

#23Nan Fung Group Holdings LtdSmart money

Notable overlap · 6 shared positions

$RYTM $RVMD $KYMR $MDGL $ARGX $INSM

$131M

25 positions

#24HighVista Strategies LLCPassive

Notable overlap · 12 shared positions

$RVMD $GPCR $ELVN $PHVS $TVTX $COGT

$439M

147 positions

#25Ishara Investments LPActive

Notable overlap · 11 shared positions

$TVTX $INSM $RARE $SRRK $ELVN $ALNY

$136M

41 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.