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Hedge Funds Similar to Catalio

13F Portfolio OverlapQ2 2026Catalio portfolio →
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Most similar hedge funds by 13F overlap

Catalio Capital Management, LP is an institutional investor managing $532M across 39 U.S. equity positions as of Q2 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to Catalio are SR ONE, Sofinnova Ventures, PSP Research, with shared positions in $AVLN, $MLYS, $ODTX, $MANE, $RARE, $NTRA. The full ranking of 25 similar funds is below.

#1SR ONE CAPITAL MANAGEMENT, LPSmart money
Notable overlap · 5 shared positions
$AVLN$MLYS$ODTX$MANE$RARE
$1.0B
15 positions
#2Sofinnova Ventures IncActive
Notable overlap · 9 shared positions
$NTRA$BMY$GILD$AXSM$RARE$DYN
$1.9B
57 positions
#3PSP Research LLCActive
Notable overlap · 8 shared positions
$INCY$IRON$RARE$DFTX$SNDX$PTGX
$188M
75 positions
#4Bellevue Group AGActive
Notable overlap · 7 shared positions
$GILD$BBIO$EW$RARE$AVLN$IMCR
$4.8B
148 positions
#5RA CAPITAL MANAGEMENT, L.P.Smart money
Notable overlap · 6 shared positions
$PBLS$SEPN$MLYS$IRON$DFTX$FDMT
$11.5B
84 positions
#6Knott David M JrActive
Notable overlap · 4 shared positions
$SNDX$BBIO$PTGX$RARE
$189M
84 positions
#7Aisling Capital Management LPSmart money
Notable overlap · 3 shared positions
$BBIO$SNDX$BBOT
$472M
14 positions
#8ORBIMED ADVISORS LLCActive
Notable overlap · 8 shared positions
$GPCR$CRVS$EW$NTRA$MLYS$ODTX
$5.4B
129 positions
#9FARALLON CAPITAL MANAGEMENT LLCActive
Notable overlap · 4 shared positions
$BBIO$NTRA$PTGX$PBLS
$21.7B
89 positions
#10SECTOR GAMMA ASActive
Notable overlap · 4 shared positions
$BMY$INCY$EW$SNDX
$461M
40 positions
#11SPHERA FUNDS MANAGEMENT LTD.Active
Notable overlap · 4 shared positions
$MLYS$SNDX$BBIO$RARE
$767M
105 positions
#12Trails Edge Capital Partners, LPActive
Notable overlap · 5 shared positions
$SNDX$INCY$KLRA$FDMT$IMCR
$630M
35 positions
#13RTW INVESTMENTS, LPActive
Notable overlap · 6 shared positions
$PTGX$NTRA$RARE$KLRA$IMCR$GPCR
$11.7B
84 positions
#14Davern Capital Partners, LPActive
Notable overlap · 3 shared positions
$NTRA$MLYS$GPCR
$587M
15 positions
#15Novo Holdings A/SActive
Notable overlap · 4 shared positions
$AVLN$FDMT$DYN$BBOT
$1.7B
25 positions
#16Jones Hill Capital LPActive
Notable overlap · 5 shared positions
$GILD$SNDX$IMCR$DNTH$GPCR
$470M
29 positions
#17SILVERARC CAPITAL MANAGEMENT, LLCActive
Notable overlap · 5 shared positions
$SNDX$DFTX$AVLN$MANE$DNTH
$962M
73 positions
#18Siren, L.L.C.Active
Notable overlap · 8 shared positions
$PBLS$DFTX$IRON$SEPN$MANE$KLRA
$4.9B
117 positions
#19Cormorant Asset Management, LPActive
Notable overlap · 7 shared positions
$PBLS$BBIO$DFTX$KLRA$DNTH$BBOT
$2.0B
50 positions
#20Ishara Investments LPActive
Notable overlap · 4 shared positions
$BBIO$MLYS$AXSM$RARE
$136M
41 positions
#21HealthInvest Partners ABActive
Notable overlap · 5 shared positions
$BBIO$EW$INCY$GILD$IRON
$372M
39 positions
#22PFM Health Sciences, LPActive
Notable overlap · 6 shared positions
$EW$AXSM$BBIO$DFTX$GILD$DNTH
$1.2B
98 positions
#23Rhenman & Partners Asset Management ABActive
Notable overlap · 5 shared positions
$EW$GILD$NTRA$AXSM$SNDX
$1.1B
99 positions
#24KVP Capital Advisors, LPActive
Notable overlap · 4 shared positions
$PTGX$IRON$AXSM$MLYS
$136M
35 positions
#25Palo Alto Investors LPActive
Notable overlap · 5 shared positions
$SNDX$IRON$RARE$DYN$EW
$724M
52 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.