PFM Health Sciences, LP
Sector Allocation
- Healthcare99.0%$1.1B
- Technology0.8%$8.9M
- Consumer Staples0.2%$2.1M
AUM History
13fpro.ai/research/fund/pfm-health-sciences-lp-1442756
Conviction and streaks
Diversifying · top 10 = 34.3%From the fund's last 12 quarters of 13F filings: positions held longest at size, and names it added to or trimmed several quarters running.
Largest positions — Q2 2026
ASND
$62.2MAXSM
$53.8MLLY
$47.1MJAZZ
$38.7MHUM
$37.5MUNH
$36.7MNBIX
$36.0MINBX
$29.2MUTHR
$27.1MRVMD
$26.8MICLR
$23.7MTHC
$23.7MEW
$22.7MWAT
$22.4MPEN
$19.0MBBIO
$18.9MSYK
$17.8MMTD
$17.0MINDV
$16.5MMRK
$16.3M
Top 20 stock positions. Options are left out: 13F reports them at the underlying's value.
13fpro.ai/research/fund/pfm-health-sciences-lp-1442756
PFM Health Sciences, LP 13F holdings — Q2 2026
$1.2B portfolio (+6.3% QoQ) · 98 holdings · Q2 2026 13F · top 10 are 34% of the stock portfolio
Includes $13.6M of put/call options ($5.7M puts, $8.0M calls), which 13F rules report at the value of the underlying shares, not the premium at risk. Stocks alone: $1.2B. Weights use the stock portfolio.
$62.2M
5.4% of stocks
-98%This quarter-1.4%Since filed10+ qtrsHeld$53.8M
4.7% of stocks
-17%This quarter-32.6%Since filed10+ qtrsHeld$47.1M
4.1% of stocks
-40%This quarter+8.4%Since filed10+ qtrsHeld$38.7M
3.4% of stocks
-10%This quarter-16.0%Since filed3 qtrsHeld$37.5M
3.3% of stocks
NewThis quarter+7.2%Since filedNew this quarterHeld$36.7M
3.2% of stocks
+52%This quarter+2.2%Since filed3 qtrsHeldAIQualityAI quality score is Pro: unlock with a free trialEst. buyEstimated buy price is Pro: unlock with a free trialAdded 3 qtrs in a row$36.0M
3.1% of stocks
-1%This quarter-4.5%Since filed5 qtrsHeld$29.2M
2.5% of stocks
+1.0%This quarter+0.3%Since filed9 qtrsHeld$27.1M
2.4% of stocks
+26%This quarter+18.6%Since filed5 qtrsHeld$26.8M
2.3% of stocks
+2%This quarter-9.7%Since filed4 qtrsHeld
All holdings — PFM Health Sciences, LP (Q2 2026)
98 disclosed positions from the Form 13F-HR on SEC EDGAR, with quarter-over-quarter share changes. Largest by value first; the ten above are not repeated.
| # | Company | Held | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 11 | ICON PLC | Healthcare | $23.7M | 2.1% | 136K | +137% | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 12 | TENET HEALTHCARE CORP | Healthcare | $23.7M | 2.1% | 127K | -68% | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 13 | Edwards Lifesciences Corp | Healthcare | $22.7M | 2.0% | 250K | -2% | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 14 | WATERS CORP /DE/ | Healthcare | $22.4M | 1.9% | 60K | +50% | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 15 | Penumbra Inc | Healthcare | $19.0M | 1.6% | 60K | -57% | 10+ qtrsTrimmed 3 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 16 | BridgeBio Pharma, Inc. | Healthcare | $18.9M | 1.6% | 253K | -2% | 7 qtrsTrimmed 5 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 17 | STRYKER CORP | Healthcare | $17.8M | 1.6% | 57K | +158% | 3 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 18 | METTLER TOLEDO INTERNATIONAL INC/ | Healthcare | $17.0M | 1.5% | 13K | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 19 | Indivior Pharmaceuticals, Inc. | Healthcare | $16.5M | 1.4% | 401K | -30% | 6 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 20 | Merck & Co., Inc. | Healthcare | $16.3M | 1.4% | 127K | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 21 | CYTOKINETICS INC | Healthcare | $16.3M | 1.4% | 192K | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 22 | Lantheus Holdings, Inc. | Healthcare | $16.2M | 1.4% | 146K | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 23 | CENTENE CORP | Healthcare | $16.0M | 1.4% | 249K | -6% | 4 qtrsTrimmed 2 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 24 | COOPER COMPANIES, INC. | Healthcare | $15.8M | 1.4% | 221K | +30% | 4 qtrsAdded 4 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 25 | MADRIGAL PHARMACEUTICALS, INC. | Healthcare | $15.7M | 1.4% | 29K | -14% | 3 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 26 | $ACHC | Acadia Healthcare Company, Inc. | Healthcare | $15.5M | 1.4% | 525K | -10% | |||
| 27 | $ORKA | Oruka Therapeutics, Inc. | Healthcare | $15.1M | 1.3% | 159K | -9% | |||
| 28 | $OSCR | Oscar Health, Inc. | Healthcare | $14.8M | 1.3% | 519K | +4% | |||
| 29 | $TMO | THERMO FISHER SCIENTIFIC INC. | Healthcare | $14.3M | 1.2% | 28K | +92% | |||
| 30 | $CVS | CVS HEALTH Corp | Healthcare | $14.2M | 1.2% | 137K | New | |||
| 31 | $MMSI | MERIT MEDICAL SYSTEMS INC | Healthcare | $13.7M | 1.2% | 197K | +21% | |||
| 32 | $PRAX | Praxis Precision Medicines, Inc. | Healthcare | $12.9M | 1.1% | 39K | +9% | |||
| 33 | $CLDX | Celldex Therapeutics, Inc. | Healthcare | $12.8M | 1.1% | 343K | +5% | |||
| 34 | $NVO | NOVO NORDISK A S | Healthcare | $12.7M | 1.1% | 265K | +34% | |||
| 35 | $ITGR | Integer Holdings Corp | Healthcare | $11.8M | 1.0% | 127K | -6% | |||
| 36 | $DNTH | Dianthus Therapeutics, Inc. /DE/ | Healthcare | $11.8M | 1.0% | 121K | -30% | |||
| 37 | $DFTX | Definium Therapeutics, Inc. | Healthcare | $11.7M | 1.0% | 249K | +21% | |||
| 38 | $GILD | GILEAD SCIENCES, INC. | Healthcare | $11.5M | 1.0% | 91K | New | |||
| 39 | $RYTM | RHYTHM PHARMACEUTICALS, INC. | Healthcare | $11.3M | 1.0% | 102K | -26% | |||
| 40 | $HSIC | HENRY SCHEIN INC | Healthcare | $11.2M | 1.0% | 134K | -12% | |||
| 41 | $ARWR | ARROWHEAD PHARMACEUTICALS, INC. | Healthcare | $10.7M | 0.9% | 132K | +105% | |||
| 42 | $TNGX | Tango Therapeutics, Inc. | Healthcare | $10.2M | 0.9% | 326K | -20% | |||
| 43 | $TFX | TELEFLEX INC | Healthcare | $10.1M | 0.9% | 80K | New | |||
| 44 | $VKTX | Viking Therapeutics, Inc. | Healthcare | $10.0M | 0.9% | 255K | -3% | |||
| 45 | $BTSG | BrightSpring Health Services, Inc. | Healthcare | $9.9M | 0.9% | 142K | -24% | |||
| 46 | $VERA | Vera Therapeutics, Inc. | Healthcare | $9.6M | 0.8% | 224K | +28% | |||
| 47 | $ROIV | Roivant Sciences Ltd. | Healthcare | $9.5M | 0.8% | 268K | +29% | |||
| 48 | $CGON | CG Oncology, Inc. | Healthcare | $9.1M | 0.8% | 128K | -23% | |||
| 49 | $AMRX | Amneal Pharmaceuticals, Inc. | Healthcare | $8.3M | 0.7% | 481K | -48% | |||
| 50 | $EPRX | EUPRAXIA PHARMACEUTICALS INC. | Healthcare | $8.0M | 0.7% | 1.21M | +124% | |||
| 51 | $COR CALL | Cencora, Inc. | Consumer Staples | $8.0M | — | 28K | New | |||
| 52 | $IRTC | iRhythm Holdings, Inc. | Healthcare | $7.8M | 0.7% | 65K | New | |||
| 53 | $KOD | Kodiak Sciences Inc. | Healthcare | $7.5M | 0.7% | 193K | +69% | |||
| 54 | $ABT | ABBOTT LABORATORIES | Healthcare | $7.5M | 0.7% | 82K | -41% | |||
| 55 | $WST | WEST PHARMACEUTICAL SERVICES INC | Healthcare | $7.4M | 0.7% | 21K | New | |||
| 56 | $TAK | TAKEDA PHARMACEUTICAL CO LTD | Healthcare | $7.1M | 0.6% | 444K | New | |||
| 57 | $HNGE | Hinge Health, Inc. | Technology | $6.9M | 0.6% | 83K | New | |||
| 58 | $ARQT | Arcutis Biotherapeutics, Inc. | Healthcare | $6.3M | 0.6% | 242K | New | |||
| 59 | $IART | INTEGRA LIFESCIENCES HOLDINGS CORP | Healthcare | $6.3M | 0.5% | 349K | New | |||
| 60 | $ILMN | ILLUMINA, INC. | Healthcare | $6.2M | 0.5% | 35K | +21% | |||
| 61 | $MGTX | MeiraGTx Holdings plc | Healthcare | $6.2M | 0.5% | 455K | New | |||
| 62 | $OCS | Oculis Holding AG | Healthcare | $6.0M | 0.5% | 436K | New | |||
| 63 | $NTRA | Natera, Inc. | Healthcare | $6.0M | 0.5% | 22K | -63% | |||
| 64 | $ABVX | Abivax S.A. | Healthcare | $5.8M | 0.5% | 43K | +62% | |||
| 65 | $CNC PUT | CENTENE CORP | Healthcare | $5.7M | — | 88K | New | |||
| 66 | $GH | Guardant Health, Inc. | Healthcare | $5.5M | 0.5% | 37K | New | |||
| 67 | $CELC | Celcuity Inc. | Healthcare | $5.5M | 0.5% | 52K | New | |||
| 68 | $BLTE | BELITE BIO, INC | Healthcare | $5.4M | 0.5% | 35K | -41% | |||
| 69 | $GPCR | Structure Therapeutics Inc. | Healthcare | $4.9M | 0.4% | 92K | -28% | |||
| 70 | $RCUS | Arcus Biosciences, Inc. | Healthcare | $4.7M | 0.4% | 152K | New | |||
| 71 | $CRL | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | Healthcare | $4.3M | 0.4% | 19K | New | |||
| 72 | $ELAN | Elanco Animal Health Inc | Healthcare | $4.2M | 0.4% | 172K | New | |||
| 73 | $ARGX | ARGENX SE | Healthcare | $4.2M | 0.4% | 4,482 | -1% | |||
| 74 | $BIO | BIO-RAD LABORATORIES, INC. | Healthcare | $4.1M | 0.4% | 14K | New | |||
| 75 | $SYRE | Spyre Therapeutics, Inc. | Healthcare | $4.1M | 0.4% | 46K | New | |||
| 76 | $MBX | MBX Biosciences, Inc. | Healthcare | $3.9M | 0.3% | 71K | -1% | |||
| 77 | $MIRM | Mirum Pharmaceuticals, Inc. | Healthcare | $3.7M | 0.3% | 32K | New | |||
| 78 | $CGEM | Cullinan Therapeutics, Inc. | Healthcare | $3.5M | 0.3% | 192K | -15% | |||
| 79 | $CMPS | COMPASS Pathways plc | Healthcare | $3.5M | 0.3% | 248K | -82% | |||
| 80 | $HCA | HCA Healthcare, Inc. | Healthcare | $3.2M | 0.3% | 8,295 | -38% | |||
| 81 | $CAPR | CAPRICOR THERAPEUTICS, INC. | Healthcare | $2.9M | 0.3% | 122K | -1% | |||
| 82 | $DNLI | Denali Therapeutics Inc. | Healthcare | $2.6M | 0.2% | 101K | New | |||
| 83 | $SNDX | Syndax Pharmaceuticals Inc | Healthcare | $2.6M | 0.2% | 118K | -52% | |||
| 84 | $AMLX | Amylyx Pharmaceuticals, Inc. | Healthcare | $2.6M | 0.2% | 144K | -1% | |||
| 85 | $TARS | Tarsus Pharmaceuticals, Inc. | Healthcare | $2.6M | 0.2% | 41K | -49% | |||
| 86 | $OM | Outset Medical, Inc. | Healthcare | $2.5M | 0.2% | 582K | -2% | |||
| 87 | $OMDA | Omada Health, Inc. | Healthcare | $2.5M | 0.2% | 114K | New | |||
| 88 | $ERAS | Erasca, Inc. | Healthcare | $2.5M | 0.2% | 134K | New | |||
| 89 | $COR | Cencora, Inc. | Consumer Staples | $2.1M | 0.2% | 7,385 | New | |||
| 90 | $BCRX | BIOCRYST PHARMACEUTICALS INC | Healthcare | $2.1M | 0.2% | 207K | New | |||
| 91 | $OMCL | OMNICELL, INC. | Technology | $2.0M | 0.2% | 49K | New | |||
| 92 | $CVRX | CVRx, Inc. | Healthcare | $1.9M | 0.2% | 370K | New | |||
| 93 | $HIMS | Hims & Hers Health, Inc. | Healthcare | $1.7M | 0.1% | 49K | New | |||
| 94 | $MLYS | Mineralys Therapeutics, Inc. | Healthcare | $1.7M | 0.1% | 62K | -56% | |||
| 95 | $TECX | Tectonic Therapeutic, Inc. | Healthcare | $1.6M | 0.1% | 46K | -1% | |||
| 96 | $QURE | uniQure N.V. | Healthcare | $1.2M | 0.1% | 26K | -38% | |||
| 97 | $RZLT | Rezolute, Inc. | Healthcare | $662K | 0.1% | 127K | -1% | |||
| 98 | $CRBU | Caribou Biosciences, Inc. | Healthcare | $624K | 0.1% | 355K | -63% |
What changed in Q2 2026
Against the previous quarter's 13F: 34 new, 22 added to, 42 trimmed, 18 sold out. Share-count changes; largest moves by dollar size first.
New positions (34)
$HUMHUMANA INC$37.5M
first bought this quarter
$MTDMETTLER TOLEDO INTERNATIONAL INC/$17.0M
first bought this quarter
$MRKMerck & Co., Inc.$16.3M
first bought this quarter
$CYTKCYTOKINETICS INC$16.3M
first bought this quarter
$LNTHLantheus Holdings, Inc.$16.2M
first bought this quarter
$CVSCVS HEALTH Corp$14.2M
first bought this quarter
+28 more in the Excel export
Added to (22)
$ICLRICON PLC+137%
now $23.7M · held 10+ qtrs
$UNHUNITEDHEALTH GROUP INC+52%
now $36.7M · held 3 qtrs, 3 adds in a row
$SYKSTRYKER CORP+158%
now $17.8M · held 3 qtrs
$WATWATERS CORP /DE/+50%
now $22.4M · held 10+ qtrs
$TMOTHERMO FISHER SCIENTIFIC INC.+92%
now $14.3M · held 4 qtrs
$UTHRUNITED THERAPEUTICS Corp+26%
now $27.1M · held 5 qtrs
+16 more in the Excel export
Trimmed (42)
$ASNDAscendis Pharma A/S-98%
now $62.2M · held 10+ qtrs
$THCTENET HEALTHCARE CORP-68%
now $23.7M · held 10+ qtrs
$LLYELI LILLY & Co-40%
now $47.1M · held 10+ qtrs, 6 trims in a row
$PENPenumbra Inc-57%
now $19.0M · held 10+ qtrs, 3 trims in a row
$CMPSCOMPASS Pathways plc-82%
now $3.5M · held 10+ qtrs
$AXSMAxsome Therapeutics, Inc.-17%
now $53.8M · held 10+ qtrs
+36 more in the Excel export
Holdings by quarter
Every 13F PFM Health Sciences, LP has filed, 40 earlier quarters. Pick one to see what it held then.
Is it too late to follow PFM Health Sciences?
Q2 2026 13F filed with the SEC on Aug 14, 2026. Prices are closing prices as of Oct 26, 2026.
Average quality of PFM Health Sciences's top 20 holdings: 60/100 (our AI quality score, weighted by position size; 17 of the 20 are scored)
Top 10 since filing
-4.1%
Value-weighted move of the 10 largest stock positions
Turnover
32%
Last quarter; 110% over the last 4
Top 10 weight
34%
Share of the stock portfolio in its 10 largest positions
Held 4+ quarters
52%
Share of portfolio value in positions held a year or more
Highest-quality names it owns(among its 100 largest positions)
The 8 highest-scoring companies in this portfolio are a Pro feature.
How these are measured
- Moves since the quarter-end and since the filing date use our own daily closing prices, from the close on (or just before) each date to the latest close.
- Turnover is the lesser of shares bought or sold in a quarter, valued at the quarter-end prices in the 13F, divided by the average of the two quarters' stock portfolio values.
- Quarters held and add/trim streaks count back only through quarters whose filed holdings add up to the filing's own cover-page total (back to Q1 2024 for this fund). A change counts as an add or a trim when the split-adjusted share count moves by more than 1%.
- Estimate, not the fund's reported cost. For each quarter in the current holding period in which the fund's share count rose (split-adjusted), we take that quarter's average daily close and weight it by the shares added; sales do not change an average cost. Quarters where the stock's price history and the 13F's own implied price disagree by more than 2x are left out.
- Put and call option rows report the value of the underlying shares, not a position the fund paid for, so they are left out of all of the above.
Portfolio Overview
PFM Health Sciences, LP disclosed 98 positions worth $1.2B in its Form 13F-HR for Q2 2026 — $1.2B in common stock plus $13.6M of put/call option positions (reported at underlying notional value, not premium at risk), led by $ASND (Ascendis Pharma A/S) at 5.4% of the equity portfolio, followed by $AXSM and $LLY. During the quarter the fund opened 34 new positions and exited 18 — including a new stake in $HUM. The portfolio is most concentrated in Healthcare (99.0% of disclosed assets). All figures are sourced directly from PFM Health Sciences, LP’s Form 13F-HR filing with the SEC under CIK 1442756.
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