What hedge funds are most similar to BAKER BROS. ADVISORS LP?

The funds with the most similar 13F portfolios to BAKER BROS. ADVISORS LP are Nan Fung Group Ltd, Rock Springs, First Turn, based on overlapping conviction holdings in the latest SEC filings.

How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to BAKER BROS. ADVISORS

13F Portfolio OverlapQ2 2026BAKER BROS. ADVISORS portfolio →

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Most similar hedge funds by 13F overlap

BAKER BROS. ADVISORS LP is an institutional investor managing $20.0B across 84 U.S. equity positions as of Q2 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to BAKER BROS. ADVISORS are Nan Fung Group Ltd, Rock Springs, First Turn, with shared positions in $INCY, $ONC, $RYTM, $RVMD, $KYMR, $MDGL. The full ranking of 25 similar funds is below.

#1Nan Fung Group Holdings LtdSmart money

Substantial overlap · 9 shared positions

$INCY $ONC $RYTM $RVMD $KYMR $MDGL

$131M

25 positions

#2Rock Springs Capital Management LPActive

Substantial overlap · 9 shared positions

$RVMD $MDGL $RYTM $KYMR $INSM $GPCR

$2.0B

104 positions

#3First Turn Management, LLCActive

Substantial overlap · 11 shared positions

$RVMD $CELC $INSM $PRAX $RYTM $KYMR

$935M

31 positions

#4Integral Health Asset Management, LLCActive

Substantial overlap · 7 shared positions

$RVMD $INSM $RYTM $ROIV $IONS $EWTX

$2.5B

92 positions

#5Avoro Capital Advisors LLCSmart money

Substantial overlap · 7 shared positions

$MDGL $KYMR $RVMD $CELC $ARWR $GPCR

$11.1B

26 positions

#6BVF INC/ILActive

Substantial overlap · 7 shared positions

$RVMD $KYMR $ALKS $STOK $GLUE $GPCR

$3.9B

44 positions

#7Boxer Capital Management, LLCSmart money

Substantial overlap · 7 shared positions

$RVMD $KOD $KYMR $CELC $PRAX $REPL

$1.3B

63 positions

#8Artia Global Partners LPActive

Notable overlap · 12 shared positions

$RVMD $INSM $ALKS $CELC $ROIV $IONS

$542M

48 positions

#9RTW INVESTMENTS, LPActive

Notable overlap · 10 shared positions

$MDGL $INSM $CELC $ACAD $IMVT $ALKS

$11.7B

84 positions

#10DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)Active

Notable overlap · 9 shared positions

$RVMD $CELC $PRAX $IDYA $ARWR $IONS

$9.6B

82 positions

#11Siren, L.L.C.Active

Notable overlap · 12 shared positions

$KYMR $RVMD $ONC $RYTM $ARWR $EWTX

$4.9B

117 positions

#12DAFNA Capital Management LLCActive

Notable overlap · 11 shared positions

$RVMD $ALKS $IMVT $IDYA $EWTX $KYMR

$524M

88 positions

#13PERCEPTIVE ADVISORS LLCActive

Notable overlap · 11 shared positions

$CELC $RYTM $PRAX $RVMD $IMVT $ROIV

$6.7B

109 positions

#14Darwin Global Management, Ltd.Smart money

Notable overlap · 3 shared positions

$RVMD $INSM $ROIV

$3.8B

5 positions

#15Eagle Health Investments LPActive

Notable overlap · 6 shared positions

$INSM $RVMD $KYMR $ALKS $IONS $DNTH

$603M

27 positions

#16HealthInvest Partners ABActive

Notable overlap · 9 shared positions

$RVMD $ONC $ALKS $INCY $INSM $CELC

$372M

39 positions

#17StemPoint Capital LPPassive

Notable overlap · 10 shared positions

$RVMD $ALKS $PRAX $CELC $IMVT $KNSA

$581M

84 positions

#18SILVERARC CAPITAL MANAGEMENT, LLCActive

Notable overlap · 8 shared positions

$CELC $RYTM $PRAX $KOD $IMVT $GLUE

$962M

73 positions

#19DIADEMA PARTNERS LPPassive

Notable overlap · 9 shared positions

$RVMD $KYMR $KOD $SMMT $EWTX $REPL

$791M

149 positions

#20Affinity Asset Advisors, LLCActive

Notable overlap · 11 shared positions

$INSM $PRAX $ALKS $RVMD $MDGL $ROIV

$2.2B

113 positions

#21Patient Square Capital LPActive

Notable overlap · 7 shared positions

$RVMD $ONC $KYMR $ROIV $DNTH $MIRM

$646M

23 positions

#22FARALLON CAPITAL MANAGEMENT LLCActive

Notable overlap · 5 shared positions

$RVMD $GRAL $IMVT $ROIV $CRNX

$21.7B

89 positions

#23Paradigm Biocapital Advisors LPActive

Notable overlap · 4 shared positions

$RVMD $INSM $EWTX $VRDN

$5.3B

28 positions

#24Casdin Capital, LLCSmart money

Notable overlap · 6 shared positions

$RVMD $GRAL $DNLI $GPCR $RLAY $GLUE

$2.0B

43 positions

#25Nextech Invest, Ltd.Smart money

Notable overlap · 5 shared positions

$RVMD $KYMR $GLUE $ALMS $RLAY

$2.1B

15 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.