What hedge funds are most similar to BAKER BROS. ADVISORS LP?

The funds with the most similar 13F portfolios to BAKER BROS. ADVISORS LP are Nan Fung Group Ltd, RTW INVESTMENTS,, Boxer ,, based on overlapping conviction holdings in the latest SEC filings.

How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to BAKER BROS. ADVISORS

13F Portfolio OverlapQ1 2026BAKER BROS. ADVISORS portfolio →

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Most similar hedge funds by 13F overlap

BAKER BROS. ADVISORS LP is an institutional investor managing $17.4B across 84 U.S. equity positions as of Q1 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to BAKER BROS. ADVISORS are Nan Fung Group Ltd, RTW INVESTMENTS,, Boxer ,, with shared positions in $INCY, $ONC, $RYTM, $CELC, $MDGL, $KYMR. The full ranking of 25 similar funds is below.

#1Nan Fung Group Holdings LtdSmart money

Substantial overlap · 10 shared positions

$INCY $ONC $RYTM $CELC $MDGL $KYMR

$121M

24 positions

#2RTW INVESTMENTS, LPActive

Substantial overlap · 8 shared positions

$INSM $MDGL $CELC $ACAD $IMVT $STOK

$10.0B

88 positions

#3Boxer Capital Management, LLCSmart money

Substantial overlap · 8 shared positions

$RVMD $KOD $KYMR $CELC $PRAX $ABVX

$762M

54 positions

#4SILVERARC CAPITAL MANAGEMENT, LLCActive

Notable overlap · 11 shared positions

$CELC $KOD $RYTM $PRAX $ALKS $IMVT

$980M

73 positions

#5Integral Health Asset Management, LLCActive

Notable overlap · 10 shared positions

$INSM $RVMD $RYTM $EWTX $ROIV $ARWR

$2.1B

90 positions

#6Rock Springs Capital Management LPActive

Notable overlap · 8 shared positions

$RVMD $MDGL $INSM $RYTM $KYMR $GPCR

$1.7B

100 positions

#7First Turn Management, LLCActive

Notable overlap · 12 shared positions

$RVMD $INSM $CELC $KYMR $PRAX $ROIV

$895M

33 positions

#8Avoro Capital Advisors LLCActive

Notable overlap · 8 shared positions

$MDGL $KYMR $CELC $RVMD $ARWR $ALKS

$10.2B

32 positions

#9HealthInvest Partners ABActive

Notable overlap · 11 shared positions

$ONC $RVMD $INCY $ALKS $INSM $CELC

$310M

39 positions

#10Siren, L.L.C.Active

Notable overlap · 13 shared positions

$KYMR $ONC $RVMD $RYTM $EWTX $ARWR

$3.6B

100 positions

#11Logos Global Management LPActive

Notable overlap · 12 shared positions

$RVMD $PRAX $MDGL $RYTM $ACAD $IMVT

$2.0B

66 positions

#12PERCEPTIVE ADVISORS LLCActive

Notable overlap · 11 shared positions

$CELC $PRAX $RYTM $EWTX $IMVT $ROIV

$5.1B

94 positions

#13StemPoint Capital LPActive

Notable overlap · 15 shared positions

$RVMD $PRAX $CELC $EWTX $ACAD $IMVT

$515M

82 positions

#14Affinity Asset Advisors, LLCActive

Notable overlap · 11 shared positions

$INSM $PRAX $ALKS $MDGL $ROIV $ARWR

$1.9B

105 positions

#15Palo Alto Investors LPActive

Notable overlap · 6 shared positions

$INSM $ACAD $ALKS $STOK $DNLI $MIRM

$654M

51 positions

#16Patient Square Capital LPSmart money

Notable overlap · 10 shared positions

$INSM $ONC $CELC $KYMR $ROIV $ABVX

$564M

29 positions

#17Artia Global Partners LPActive

Notable overlap · 11 shared positions

$INSM $RVMD $IONS $ROIV $ABVX $EWTX

$499M

50 positions

#18Eagle Health Investments LPActive

Notable overlap · 4 shared positions

$INSM $KYMR $RVMD $ALKS

$572M

28 positions

#19Darwin Global Management, Ltd.Active

Notable overlap · 5 shared positions

$INSM $RVMD $ROIV $ABVX $DNTH

$3.8B

6 positions

#20BVF INC/ILActive

Notable overlap · 7 shared positions

$RVMD $KYMR $ALKS $STOK $GLUE $GPCR

$3.1B

41 positions

#21Soleus Capital Management, L.P.Active

Notable overlap · 6 shared positions

$CELC $PRAX $ALKS $EWTX $KNSA $MIRM

$2.5B

93 positions

#22DIADEMA PARTNERS LPPassive

Notable overlap · 8 shared positions

$RVMD $KOD $INCY $ALKS $ABVX $GLUE

$588M

144 positions

#23Paradigm Biocapital Advisors LPActive

Notable overlap · 8 shared positions

$RVMD $INSM $EWTX $ABVX $GPCR $SYRE

$4.9B

35 positions

#24KVP Capital Advisors, LPActive

Notable overlap · 7 shared positions

$INSM $PRAX $RVMD $EWTX $IDYA $CELC

$134M

32 positions

#25Exome Asset Management LLCPassive

Notable overlap · 9 shared positions

$PRAX $INSM $RYTM $ALKS $IONS $ARWR

$193M

56 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.