Zai Lab Ltd(ZLAB)Stock Analysis
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This company passes all size and coverage filters but hasn't been included in the latest quarterly ranking run. Rankings refresh on Jan 1, Apr 1, Jul 1, Oct 1.
Financial data, filings, and institutional holdings below are still tracked in full — only the proprietary quality composite is unavailable for this name.
ZLAB Stock Analysis & AI Quality Score
AI stock analysis and institutional research for Zai Lab Ltd (ZLAB), a Healthcare sector company. ZLAB is not currently included in 13F Pro's AI-ranked quality universe — this company passes all size and coverage filters but hasn't been included in the latest quarterly ranking run. rankings refresh on jan 1, apr 1, jul 1, oct 1. Based on the latest XBRL financial filings (Q1 2026), Zai Lab Ltd reports quarterly revenue of $99.6M, net income of $-51.0M, free cash flow of $-13.1M. Top institutional holders of ZLAB by reported 13-F value include RTW INVESTMENTS,, RA CAPITAL MANAGEMENT, L.P., Frazier Life Sciences Management, L.P., based on the most recent SEC filings. ZLAB trades on the Nasdaq exchange and files with the SEC under CIK 1704292. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate ZLAB daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for Zai Lab Ltd directly from SEC EDGAR.
Revenue
Q1 2026
$99.6M
Net Income
Q1 2026
$-51.0M
Free Cash Flow
Q1 2026
$-13.1M
D/E Ratio
Q1 2026
0.32
Revenue & Net Income
Earnings Per Share
Key Financials Over Time
Export Financial Table · Pro+Revenue
+15.3% YoYNet Income
+31.7% YoYOperating Income
+18.7% YoYEPS (Diluted)
+38.5% YoYTotal Assets
-1.1% YoYTotal Debt
+55.3% YoYOp. Cash Flow
+29.8% YoY| Metric | FY 2025 | FY 2024 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|
| Revenue | $460.2M +15.3% | $399.0M +85.5% | $215.0M +49.0% | $144.3M +194.8% | $49.0M |
| Net Income | $-175.5M +31.7% | $-257.1M +42.0% | $-443.3M +37.1% | $-704.5M -162.0% | $-268.9M |
| Operating Income | $-229.4M +18.7% | $-282.1M +30.2% | $-404.4M +42.2% | $-700.1M -132.0% | $-301.8M |
| EPS (Diluted) | $-0.16 +38.5% | $-0.26 +43.5% | $-0.46 -505.3% | $-0.08 -117.1% | $-0.04 |
| Total Assets | $1.17B -1.1% | $1.19B -2.8% | $1.22B -24.2% | $1.61B +24.1% | $1.30B |
| Total Debt | $204.5M +55.3% | $131.7M | — | — | — |
| Operating Cash Flow | $-150.8M +29.8% | $-214.9M +41.6% | $-367.6M +33.1% | $-549.2M -154.2% | $-216.1M |
AI Insight: ZLAB Financial Trends
Zai Lab remains deeply unprofitable with rising debt and shrinking equity, despite modest sequential revenue growth through 2025.
• Revenue grew from $101M in Q2 2024 to $128M in Q4 2025, but dropped sharply to $100M in Q1 2026.
• Operating losses narrowed from -$76M in Q2 2024 to -$49M in Q3 2025, then widened back to -$69M in Q1 2026.
• Total debt nearly tripled from $70M in Q2 2024 to $214M in Q1 2026, while equity eroded from $704M to $662M.
• Operating cash burn improved meaningfully to -$12M in Q1 2026, the least negative level across the entire period.
⚠ Equity has declined for four consecutive quarters from $841M in Q4 2024 to $662M in Q1 2026 — balance sheet erosion accelerating.
⚠ Revenue fell $28M quarter-over-quarter in Q1 2026 — first sub-$101M print since Q2 2024; monitor for seasonal vs. structural weakness.
⚠ Debt rose to $214M in Q1 2026 with persistent operating losses; sustainability of funding runway warrants close attention.
AI Insight: ZLAB Ratio Trends
Zai Lab's loss-rate improvement reversed sharply in Q4 2025–Q1 2026, erasing six months of margin progress.
• Operating margin improved steadily from -75.7% in Q2 2024 to -42.0% in Q3 2025, a meaningful 33.7pp reduction in losses.
• That improvement reversed: operating margin deteriorated from -42.0% in Q3 2025 to -69.7% in Q1 2026.
• ROIC worsened from -20.3% in Q3 2025 to -31.7% in Q1 2026, signaling rising capital destruction pressure.
• D/E leverage has crept from 0.10 in Q2 2024 to 0.32 in Q1 2026, indicating gradual but consistent debt accumulation.
⚠ Q4 2025 and Q1 2026 back-to-back margin deterioration — monitor whether this is seasonal or a structural reversal.
⚠ D/E ratio tripled from 0.10 to 0.32 over the period; further increases could pressure the balance sheet materially.
⚠ NPM swung from -31.0% in Q3 2025 to -51.2% in Q1 2026 — watch for one-off charges driving the spike.
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Available Research
13F Pro tracks comprehensive data for Zai Lab Ltd including:
Top Institutional Holders of ZLAB
RTW INVESTMENTS, LP
$123.7M6,574,032 shRA CAPITAL MANAGEMENT, L.P.
$107.4M5,707,262 shFrazier Life Sciences Management, L.P.
$35.8M1,902,320 shCITADEL ADVISORS LLC
$31.8M1,688,632 shBAMCO INC /NY/
$31.2M1,658,318 shADAR1 Capital Management, LLC
$26.8M1,425,367 shFMR LLC
$23.7M1,262,391 shBlackRock, Inc.
$16.3M865,146 shRock Springs Capital Management LP
$15.3M814,707 shUBS Group AG
$9.5M504,191 sh
| Fund | Value | Shares |
|---|---|---|
| RTW INVESTMENTS, LP | $123.7M | 6,574,032 |
| RA CAPITAL MANAGEMENT, L.P. | $107.4M | 5,707,262 |
| Frazier Life Sciences Management, L.P. | $35.8M | 1,902,320 |
| CITADEL ADVISORS LLC | $31.8M | 1,688,632 |
| BAMCO INC /NY/ | $31.2M | 1,658,318 |
| ADAR1 Capital Management, LLC | $26.8M | 1,425,367 |
| FMR LLC | $23.7M | 1,262,391 |
| BlackRock, Inc. | $16.3M | 865,146 |
| Rock Springs Capital Management LP | $15.3M | 814,707 |
| UBS Group AG | $9.5M | 504,191 |
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Popular Research
Is ZLAB a good stock to buy?
13F Pro's AI-powered analysis of Zai Lab Ltd (ZLAB) draws on SEC EDGAR-sourced fundamentals, institutional 13F holdings, and insider Form 4 transactions in the Healthcare sector (listed on Nasdaq). The 32-signal AI Quality Score, current rank, and full bull/bear verdict for ZLAB are available on the ZLAB stock profile dashboard — with the same data, AI insights, ratios, and institutional activity refreshed after every 10-K, 10-Q, 13F, and Form 4 filing.
Which hedge funds own ZLAB?
Institutional investors are required to disclose their holdings quarterly via SEC Form 13F. 13F Pro aggregates these filings to show which hedge funds, mutual funds, and asset managers are buying or selling ZLAB. Combined with insider transaction data from Form 4 filings and AI-powered analysis from 10 specialized research agents, 13F Pro provides a comprehensive view of Zai Lab Ltd's investment landscape.