Tango Therapeutics, Inc. (TNGX) — Institutional Holders, Q2 2026
249 institutional investment managers reported a TNGX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $6.6B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
TNGX in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- PRICE T ROWE ASSOCIATESAdded · +5,459,427 sh+$170.7M
- GOLDMAN SACHS GROUPAdded · +4,904,228 sh+$153.3M
- BlackRockAdded · +3,690,399 sh+$115.4M
- FARALLON CAPITAL MANAGEMENTAdded · +3,179,589 sh+$99.4M
- Seven Fleet Capital ManagementAdded · +2,726,132 sh+$85.2M
Biggest sellers
- Nextech Invest, Ltd.Sold out · -7,266,081 sh-$227.1M
- ADAGE CAPITAL PARTNERS GP, L.L.C.Trimmed · -7,209,485 sh-$225.4M
- Woodline PartnersTrimmed · -3,999,446 sh-$125.0M
- BALYASNY ASSET MANAGEMENT L.P.Trimmed · -1,810,280 sh-$56.6M
- Bellevue Group AGTrimmed · -1,705,818 sh-$53.3M
TNGX 13F holders ranked 1–100 of 249
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | RTW INVESTMENTS#1 · 13,900,620 sh | 13,900,620 | $434.5M | 3.71% | +4.5% |
| 2 | BlackRock#2 · 12,438,444 sh | 12,438,444 | $388.8M | <0.01% | +42.2% |
| 3 | FMR#3 · 12,333,339 sh | 12,333,339 | $385.5M | 0.02% | +24.5% |
| 4 | FARALLON CAPITAL MANAGEMENT#4 · 12,277,000 sh | 12,277,000 | $383.8M | 1.77% | +35.0% |
| 5 | Boxer Capital Management#5 · 10,876,219 sh | 10,876,219 | $340.0M | 25.61% | 0.0% |
| 6 | GOLDMAN SACHS GROUP#6 · 9,980,620 sh | 9,980,620 | $312.0M | 0.03% | +96.6% |
| 7 | TCG Crossover Management#7 · 9,081,201 sh | 9,081,201 | $283.9M | 6.82% | -13.8% |
| 8 | Paradigm Biocapital Advisors#8 · 6,357,523 sh | 6,357,523 | $198.7M | 3.72% | +58.6% |
| 9 | PRICE T ROWE ASSOCIATES#9 · 6,348,827 sh | 6,348,827 | $198.5M | 0.02% | +613.8% |
| 10 | Siren, L.L.C.#10 · 6,179,364 sh | 6,179,364 | $193.2M | 3.91% | +9.2% |
| 11 | STATE STREET#11 · 5,979,806 sh | 5,979,806 | $186.9M | <0.01% | +28.5% |
| 12 | VANGUARD CAPITAL MANAGEMENT#12 · 5,957,348 sh | 5,957,348 | $186.2M | <0.01% | +15.4% |
| 13 | ADAGE CAPITAL PARTNERS GP, L.L.C.#13 · 5,600,000 sh | 5,600,000 | $175.1M | 0.25% | -56.3% |
| 14 | Jupiter Topco#14 · 5,056,352 sh | 5,056,352 | $158.0M | 0.06% | — |
| 15 | Deep Track Capital#15 · 4,200,000 sh | 4,200,000 | $131.3M | 1.91% | +52.7% |
| 16 | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)#16 · 4,190,611 sh | 4,190,611 | $131.0M | 1.37% | +1.1% |
| 17 | Woodline Partners#17 · 4,000,567 sh | 4,000,567 | $125.1M | 0.39% | -50.0% |
| 18 | TRV GP IV#18 · 6,374,574 sh | 6,374,574 | $120.2M | 47.37% | 0.0% |
| 19 | GEODE CAPITAL MANAGEMENT#19 · 3,742,791 sh | 3,742,791 | $117.0M | <0.01% | +39.9% |
| 20 | PERCEPTIVE ADVISORS#20 · 3,377,000 sh | 3,377,000 | $105.6M | 1.58% | +317.9% |
| 21 | Seven Fleet Capital Management#21 · 3,228,144 sh | 3,228,144 | $95.7M | 15.79% | +543.0% |
| 22 | Logos Global Management#22 · 2,850,000 sh | 2,850,000 | $89.1M | 3.84% | -5.0% |
| 23 | Caligan Partners#23 · 2,500,103 sh | 2,500,103 | $78.2M | 3.68% | +3.8% |
| 24 | Holocene Advisors#24 · 2,410,939 sh | 2,410,939 | $75.4M | 0.17% | -38.7% |
| 25 | Commodore Capital#25 · 2,250,000 sh | 2,250,000 | $70.3M | 4.19% | New |
| 26 | BALYASNY ASSET MANAGEMENT L.P.#26 · 2,016,379 sh | 2,016,379 | $63.0M | 0.08% | -47.3% |
| 27 | LEUCADIA NATIONAL#27 · 2,010,534 sh | 2,010,534 | $62.8M | 0.41% | New |
| 28 | FRANKLIN RESOURCES#28 · 1,887,211 sh | 1,887,211 | $59.0M | 0.01% | +45.6% |
| 29 | Candriam S.C.A.#29 · 1,630,553 sh | 1,630,553 | $50.9M | 0.23% | +28.5% |
| 30 | VANGUARD PORTFOLIO MANAGEMENT#30 · 1,585,111 sh | 1,585,111 | $49.6M | <0.01% | +75.8% |
| 31 | JPMORGAN CHASE#31 · 1,418,193 sh | 1,418,193 | $46.3M | <0.01% | +2006.5% |
| 32 | Polar Capital Plc#32 · 1,480,740 sh | 1,480,740 | $46.3M | 0.11% | New |
| 33 | Vivo Capital#33 · 1,379,769 sh | 1,379,769 | $43.1M | 3.94% | -36.0% |
| 34 | DV EQUITIES#34 · 1,318,551 sh | 1,318,551 | $41.2M | 5.91% | — |
| 35 | Cormorant Asset Management#35 · 1,300,000 sh | 1,300,000 | $40.6M | 2.08% | -8.8% |
| 36 | NORTHERN#36 · 1,231,933 sh | 1,231,933 | $38.5M | <0.01% | +42.8% |
| 37 | StemPoint Capital#37 · 1,223,019 sh | 1,223,019 | $38.2M | 6.59% | +508.7% |
| 38 | FEDERATED HERMES#38 · 1,214,613 sh | 1,214,613 | $38.0M | 0.05% | New |
| 39 | VOYA INVESTMENT MANAGEMENT#39 · 1,103,030 sh | 1,103,030 | $34.5M | 0.03% | +528.6% |
| 40 | CHARLES SCHWAB INVESTMENT MANAGEMENT#40 · 1,072,059 sh | 1,072,059 | $33.5M | <0.01% | +27.8% |
| 41 | AMERICAN CENTURY COMPANIES#41 · 1,013,794 sh | 1,013,794 | $31.7M | 0.01% | New |
| 42 | Integral Health Asset Management#42 · 1,000,000 sh | 1,000,000 | $31.3M | 1.23% | +122.2% |
| 43 | VANGUARD FIDUCIARY#43 · 915,565 sh | 915,565 | $28.6M | <0.01% | +38.1% |
| 44 | Nuveen#44 · 890,170 sh | 890,170 | $27.8M | <0.01% | +146.7% |
| 45 | SAMLYN CAPITAL#45 · 766,473 sh | 766,473 | $24.0M | 0.39% | New |
| 46 | RENAISSANCE TECHNOLOGIES#46 · 748,300 sh | 748,300 | $23.4M | 0.03% | New |
| 47 | Soleus Capital Management, L.P.#47 · 709,000 sh | 709,000 | $22.2M | 0.76% | +57.6% |
| 48 | ArrowMark Colorado#48 · 708,385 sh | 708,385 | $22.1M | 0.92% | 0.0% |
| 49 | Bellevue Group AG#49 · 694,182 sh | 694,182 | $21.7M | 0.46% | -71.1% |
| 50 | Alyeska Investment Group, L.P.#50 · 691,109 sh | 691,109 | $21.6M | 0.06% | +3918.5% |
| 51 | Connor, Clark & Lunn Investment Management Ltd.#51 · 636,070 sh | 636,070 | $19.9M | 0.04% | +79.1% |
| 52 | BANK OF AMERICA#52 · 600,834 sh | 600,834 | $18.8M | <0.01% | +83.7% |
| 53 | Pictet Asset Management Holding SA#53 · 582,262 sh | 582,262 | $18.3M | 0.02% | New |
| 54 | Fisher Asset Management#54 · 578,158 sh | 578,158 | $18.1M | <0.01% | +256.0% |
| 55 | LORD, ABBETT#55 · 532,109 sh | 532,109 | $16.6M | 0.05% | New |
| 56 | JANE STREET GROUP#56 · 514,265 sh | 514,265 | $16.1M | <0.01% | New |
| 57 | MORGAN STANLEY#57 · 510,778 sh | 510,778 | $16.0M | <0.01% | -65.4% |
| 58 | FIRST ADVISORS#58 · 509,309 sh | 509,309 | $15.9M | <0.01% | New |
| 59 | Nantahala Capital Management#59 · 500,659 sh | 500,659 | $15.7M | 0.52% | -60.0% |
| 60 | BOOTHBAY FUND MANAGEMENT#60 · 500,497 sh | 500,497 | $15.6M | 0.21% | -12.4% |
| 61 | MILLENNIUM MANAGEMENT#61 · 496,036 sh | 496,036 | $15.5M | <0.01% | +16.5% |
| 62 | DIMENSIONAL FUND ADVISORS#62 · 488,300 sh | 488,300 | $15.3M | <0.01% | -0.2% |
| 63 | Invesco Ltd.#63 · 462,721 sh | 462,721 | $14.5M | <0.01% | -20.3% |
| 64 | Rock Springs Capital Management#64 · 456,551 sh | 456,551 | $14.3M | 0.70% | +18.0% |
| 65 | BOONE CAPITAL MANAGEMENT#65 · 455,605 sh | 455,605 | $14.2M | 3.33% | New |
| 66 | Longaeva Partners L.P.#66 · 414,902 sh | 414,902 | $13.0M | 0.28% | New |
| 67 | EVENTIDE ASSET MANAGEMENT#67 · 400,000 sh | 400,000 | $12.5M | 0.17% | New |
| 68 | ACUTA CAPITAL PARTNERS#68 · 390,949 sh | 390,949 | $12.2M | 8.52% | -11.5% |
| 69 | Bank of New York Mellon#69 · 390,920 sh | 390,920 | $12.2M | <0.01% | +22.8% |
| 70 | UBS Group AG#70 · 383,694 sh | 383,694 | $12.0M | <0.01% | -45.1% |
| 71 | CONGRESS ASSET MANAGEMENT#71 · 380,746 sh | 380,746 | $11.9M | — | +11.5% |
| 72 | Mass General Brigham#72 · 354,192 sh | 354,192 | $11.1M | 3.07% | 0.0% |
| 73 | BESSEMER GROUP#73 · 354,206 sh | 354,206 | $11.1M | 0.02% | -50.0% |
| 74 | LMR Partners LLP#74 · 347,106 sh | 347,106 | $10.9M | 0.04% | New |
| 75 | Assenagon Asset Management S.A.#75 · 345,156 sh | 345,156 | $10.8M | — | New |
| 76 | BAKER BROS. ADVISORS#76 · 333,333 sh | 333,333 | $10.4M | 0.05% | New |
| 77 | PFM Health Sciences#77 · 326,047 sh | 326,047 | $10.2M | 0.87% | -19.7% |
| 78 | AMERIPRISE FINANCIAL#78 · 306,345 sh | 306,345 | $9.6M | <0.01% | -39.5% |
| 79 | Point72 Asset Management, L.P.#79 · 298,339 sh | 298,339 | $9.3M | 0.01% | -44.1% |
| 80 | WELLINGTON MANAGEMENT GROUP LLP#80 · 297,106 sh | 297,106 | $9.3M | <0.01% | +2.7% |
| 81 | SCHRODER INVESTMENT MANAGEMENT GROUP#81 · 278,511 sh | 278,511 | $9.1M | <0.01% | +34.2% |
| 82 | Handelsbanken Fonder AB#82 · 287,900 sh | 287,900 | $9.0M | 0.03% | New |
| 83 | Russell Investments Group, Ltd.#83 · 281,633 sh | 281,633 | $8.8M | <0.01% | +2093.4% |
| 84 | ALGERT GLOBAL#84 · 271,570 sh | 271,570 | $8.5M | 0.10% | +86.5% |
| 85 | HighVista Strategies#85 · 260,070 sh | 260,070 | $8.1M | 1.85% | +149.6% |
| 86 | SPHERA FUNDS MANAGEMENT LTD.#86 · 254,250 sh | 254,250 | $7.9M | 1.04% | -26.0% |
| 87 | T. Rowe Price Investment Management#87 · 252,109 sh | 252,109 | $7.9M | <0.01% | -42.7% |
| 88 | TWO SIGMA INVESTMENTS#88 · 241,783 sh | 241,783 | $7.6M | <0.01% | +39.7% |
| 89 | KVP Capital Advisors#89 · 230,264 sh | 230,264 | $7.2M | 5.28% | 0.0% |
| 90 | TD ASSET MANAGEMENT#90 · 221,968 sh | 221,968 | $6.9M | <0.01% | +116.3% |
| 91 | Sio Capital Management#91 · 208,500 sh | 208,500 | $6.5M | 1.08% | New |
| 92 | HealthInvest Partners AB#92 · 198,557 sh | 198,557 | $6.2M | 1.67% | +563.7% |
| 93 | TRV GP VI#93 · 194,174 sh | 194,174 | $6.1M | 2.61% | 0.0% |
| 94 | Walleye Capital#94 · 192,270 sh | 192,270 | $6.0M | 0.02% | New |
| 95 | Swiss National Bank#95 · 187,400 sh | 187,400 | $5.9M | <0.01% | +113.4% |
| 96 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#96 · 181,212 sh | 181,212 | $5.7M | <0.01% | +67.5% |
| 97 | CITADEL ADVISORS#97 · 181,059 sh | 181,059 | $5.7M | <0.01% | +0.9% |
| 98 | VICTORY CAPITAL MANAGEMENT#98 · 176,748 sh | 176,748 | $5.5M | <0.01% | +234.7% |
| 99 | RHUMBLINE ADVISERS#99 · 175,133 sh | 175,133 | $5.5M | <0.01% | +38.3% |
| 100 | MARSHALL WACE, LLP#100 · 174,909 sh | 174,909 | $5.5M | <0.01% | New |
Funds that sold out of TNGX in Q2 2026 (22)
Held TNGX at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Nextech Invest, Ltd.7,266,081 sh | 7,266,081 | $152.0M |
| Sofinnova Ventures395,081 sh | 395,081 | $8.3M |
| DV Trading300,648 sh | 300,648 | $6.3M |
| Parkman Healthcare Partners266,127 sh | 266,127 | $5.6M |
| Schonfeld Strategic Advisors120,689 sh | 120,689 | $2.5M |
| Atom Investors52,764 sh | 52,764 | $1.1M |
| ALLSTATE32,047 sh | 32,047 | $670.4K |
| Entropy Technologies20,656 sh | 20,656 | $432.1K |
| Gotham Asset Management19,137 sh | 19,137 | $400.3K |
| BRIDGEWAY CAPITAL MANAGEMENT14,000 sh | 14,000 | $292.9K |
| CANADA PENSION PLAN INVESTMENT BOARD13,900 sh | 13,900 | $290.8K |
| MANGROVE PARTNERS IM12,557 sh | 12,557 | $262.7K |
| SummitTX Capital, L.P.12,535 sh | 12,535 | $262.2K |
| Bridgefront Capital10,867 sh | 10,867 | $227.3K |
| Hudson Bay Capital Management10,160 sh | 10,160 | $212.5K |
| Abacus Wealth Partners9,561 sh | 9,561 | $200.0K |
| Quantbot Technologies7,408 sh | 7,408 | $155.0K |
| Advisory Services Network487 sh | 487 | $10.2K |
| Clearstead Advisors45 sh | 45 | $942.00 |
| Root Financial Partners34 sh | 34 | $711.00 |
| MAI Capital Management18 sh | 18 | $377.00 |
| TWIN PEAKS WEALTH ADVISORS2 sh | 2 | $42.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.