Commodore Capital LP
Sector Allocation
- Healthcare99.4%$1.7B
- Financials0.3%$5.3M
- Other0.3%$5.3M
AUM History
13fpro.ai/research/fund/commodore-capital-lp-1831942
Conviction and streaks
Concentrating · top 10 = 68.2%From the fund's last 12 quarters of 13F filings: positions held longest at size, and names it added to or trimmed several quarters running.
Largest positions — Q2 2026
RLAY
$224.5MELVN
$166.2MALKS
$157.2MCOGT
$118.0MAMLX
$101.5MDFTX
$94.1MSYRE
$75.2MANRO
$71.9MTNGX
$70.3MEYPT
$65.8MTYRA
$59.9MDMRA
$50.4MCLDX
$50.2MPHVS
$49.3MLBRX
$48.7MASMB
$38.9MEDIT
$28.8MKYMR
$28.7MCATX
$21.6MIPSC
$21.3M
Top 20 stock positions. Options are left out: 13F reports them at the underlying's value.
13fpro.ai/research/fund/commodore-capital-lp-1831942
Commodore Capital LP 13F holdings — Q2 2026
$1.7B portfolio (-2.9% QoQ) · 33 holdings · Q2 2026 13F · top 10 are 68% of the stock portfolio
$224.5M
13.4% of stocks
-29%This quarter-8.5%Since filed5 qtrsHeld$166.2M
9.9% of stocks
No changeThis quarter-29.4%Since filed10+ qtrsHeld$157.2M
9.4% of stocks
-29%This quarter-11.1%Since filed9 qtrsHeld$118.0M
7.0% of stocks
+6%This quarter-17.7%Since filed10+ qtrsHeld$101.5M
6.0% of stocks
No changeThis quarter+25.8%Since filed4 qtrsHeld$94.1M
5.6% of stocks
No changeThis quarter-16.3%Since filed2 qtrsHeld$75.2M
4.5% of stocks
-56%This quarter-12.8%Since filed10+ qtrsHeldAIQualityAI quality score is Pro: unlock with a free trialEst. buyEstimated buy price is Pro: unlock with a free trialTrimmed 2 qtrs in a row$71.9M
4.3% of stocks
No changeThis quarter-31.6%Since filed3 qtrsHeld$70.3M
4.2% of stocks
NewThis quarter-8.8%Since filedNew this quarterHeld$65.8M
3.9% of stocks
+63%This quarter—Since filed2 qtrsHeldAIQualityAI quality score is Pro: unlock with a free trialEst. buyEstimated buy price is Pro: unlock with a free trialAdded 2 qtrs in a row
All holdings — Commodore Capital LP (Q2 2026)
33 disclosed positions from the Form 13F-HR on SEC EDGAR, with quarter-over-quarter share changes. Largest by value first; the ten above are not repeated.
| # | Company | Held | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 11 | Tyra Biosciences, Inc. | Healthcare | $59.9M | 3.6% | 1.88M | -24% | 6 qtrsTrimmed 2 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 12 | Damora Therapeutics, Inc. | Healthcare | $50.4M | 3.0% | 1.94M | — | 2 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 13 | Celldex Therapeutics, Inc. | Healthcare | $50.2M | 3.0% | 1.35M | -50% | 6 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 14 | Pharvaris N.V. | Healthcare | $49.3M | 2.9% | 1.43M | -26% | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 15 | LB PHARMACEUTICALS INC | Healthcare | $48.7M | 2.9% | 1.50M | — | 4 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 16 | ASSEMBLY BIOSCIENCES, INC. | Healthcare | $38.9M | 2.3% | 1.42M | +42% | 4 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 17 | Editas Medicine, Inc. | Healthcare | $28.8M | 1.7% | 8.89M | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 18 | Kymera Therapeutics, Inc. | Healthcare | $28.7M | 1.7% | 250K | -67% | 5 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 19 | Perspective Therapeutics, Inc. | Healthcare | $21.6M | 1.3% | 6.34M | — | 2 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 20 | Century Therapeutics, Inc. | Healthcare | $21.3M | 1.3% | 8.70M | — | 2 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 21 | Zura Bio Ltd | Healthcare | $19.2M | 1.1% | 3.25M | — | 2 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 22 | Avalo Therapeutics, Inc. | Healthcare | $18.8M | 1.1% | 1.02M | +111% | 9 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 23 | InflaRx N.V. | Healthcare | $16.4M | 1.0% | 7.30M | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 24 | AN2 Therapeutics, Inc. | Healthcare | $14.2M | 0.8% | 2.93M | +26% | 2 qtrsAdded 2 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 25 | Nuvalent, Inc. | Healthcare | $12.3M | 0.7% | 100K | -88% | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 26 | $SABS | SAB Biotherapeutics, Inc. | Healthcare | $11.2M | 0.7% | 2.87M | -35% | |||
| 27 | $IKT | Inhibikase Therapeutics, Inc. | Healthcare | $11.0M | 0.7% | 5.40M | — | |||
| 28 | $RLMD | RELMADA THERAPEUTICS, INC. | Healthcare | $9.9M | 0.6% | 1.43M | +125% | |||
| 29 | $PEPG | PepGen Inc. | Healthcare | $8.1M | 0.5% | 4.47M | — | |||
| 30 | $RACC | Research Alliance Corp III | Financials | $5.3M | 0.3% | 500K | New | |||
| 31 | — | HELIX ACQUISITION CORP III - USD CL A ORD SHS | — | $5.3M | 0.3% | 500K | — | |||
| 32 | $LONA | LeonaBio, Inc. | Healthcare | $4.3M | 0.3% | 464K | — | |||
| 33 | $VTGN | Vistagen Therapeutics, Inc. | Healthcare | $630K | 0.0% | 2.79M | New |
What changed in Q2 2026
Against the previous quarter's 13F: 5 new, 6 added to, 9 trimmed, 8 sold out. Share-count changes; largest moves by dollar size first.
New positions (5)
Added to (6)
$EYPTEyePoint, Inc.+63%
now $65.8M · held 2 qtrs, 2 adds in a row
$ASMBASSEMBLY BIOSCIENCES, INC.+42%
now $38.9M · held 4 qtrs
$AVTXAvalo Therapeutics, Inc.+111%
now $18.8M · held 9 qtrs
$COGTCogent Biosciences, Inc.+6%
now $118.0M · held 10+ qtrs, 2 adds in a row
$RLMDRELMADA THERAPEUTICS, INC.+125%
now $9.9M · held 2 qtrs, 2 adds in a row
$ANTXAN2 Therapeutics, Inc.+26%
now $14.2M · held 2 qtrs, 2 adds in a row
Trimmed (9)
$SYRESpyre Therapeutics, Inc.-56%
now $75.2M · held 10+ qtrs, 2 trims in a row
$RLAYRelay Therapeutics, Inc.-29%
now $224.5M · held 5 qtrs
$NUVLNuvalent, Inc.-88%
now $12.3M · held 10+ qtrs
$ALKSAlkermes plc.-29%
now $157.2M · held 9 qtrs
$KYMRKymera Therapeutics, Inc.-67%
now $28.7M · held 5 qtrs
$CLDXCelldex Therapeutics, Inc.-50%
now $50.2M · held 6 qtrs
+3 more in the Excel export
Sold out (8)
$ERASErasca, Inc.was $51.4M
held 1 qtr
$XENEXenon Pharmaceuticals Inc.was $48.0M
held 9+ qtrs
$NRIXNurix Therapeutics, Inc.was $35.3M
held 7 qtrs
$CRVSCorvus Pharmaceuticals, Inc.was $33.0M
held 1 qtr
$SLNOSOLENO THERAPEUTICS INCwas $21.8M
held 9+ qtrs
$OCULOCULAR THERAPEUTIX, INCwas $21.8M
+2 more in the Excel export
Holdings by quarter
Every 13F Commodore Capital LP has filed, 22 earlier quarters. Pick one to see what it held then.
Is it too late to follow Commodore Capital?
Q2 2026 13F filed with the SEC on Aug 14, 2026. Prices are closing prices as of Oct 23, 2026.
Average quality of Commodore Capital's top 20 holdings: 22/100 (our AI quality score, weighted by position size; 9 of the 20 are scored)
Top 10 since filing
-12.4%
Value-weighted move of the 10 largest stock positions
Turnover
11%
Last quarter; 59% over the last 4
Top 10 weight
68%
Share of the stock portfolio in its 10 largest positions
Held 4+ quarters
71%
Share of portfolio value in positions held a year or more
Highest-quality names it owns(among its 100 largest positions)
The 8 highest-scoring companies in this portfolio are a Pro feature.
How these are measured
- Moves since the quarter-end and since the filing date use our own daily closing prices, from the close on (or just before) each date to the latest close.
- Turnover is the lesser of shares bought or sold in a quarter, valued at the quarter-end prices in the 13F, divided by the average of the two quarters' stock portfolio values.
- Quarters held and add/trim streaks count back only through quarters whose filed holdings add up to the filing's own cover-page total (back to Q1 2024 for this fund). A change counts as an add or a trim when the split-adjusted share count moves by more than 1%.
- Estimate, not the fund's reported cost. For each quarter in the current holding period in which the fund's share count rose (split-adjusted), we take that quarter's average daily close and weight it by the shares added; sales do not change an average cost. Quarters where the stock's price history and the 13F's own implied price disagree by more than 2x are left out.
- Put and call option rows report the value of the underlying shares, not a position the fund paid for, so they are left out of all of the above.
Portfolio Overview
Commodore Capital LP disclosed 33 positions worth $1.7B in its Form 13F-HR for Q2 2026, led by $RLAY (Relay Therapeutics, Inc.) at 13.4% of the equity portfolio, followed by $ELVN and $ALKS. During the quarter the fund opened 5 new positions and exited 8 — including a new stake in $TNGX and a full exit from $ERAS. The portfolio is most concentrated in Healthcare (99.4% of disclosed assets). All figures are sourced directly from Commodore Capital LP’s Form 13F-HR filing with the SEC under CIK 1831942.
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