Stoke Therapeutics, Inc. (STOK) — Institutional Holders, Q2 2026
198 institutional investment managers reported a STOK position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $2.5B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
STOK in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- T. Rowe Price Investment ManagementAdded · +2,164,226 sh+$70.8M
- PRICE T ROWE ASSOCIATESAdded · +727,568 sh+$23.8M
- EcoR1 CapitalAdded · +635,000 sh+$20.8M
- STATE STREETAdded · +575,728 sh+$18.8M
- BlackRockAdded · +491,643 sh+$16.1M
Biggest sellers
- Lynx1 Capital ManagementTrimmed · -725,269 sh-$23.7M
- Polar Capital PlcTrimmed · -298,795 sh-$9.8M
- BANK OF AMERICATrimmed · -283,387 sh-$9.3M
- GOLDMAN SACHS GROUPTrimmed · -255,358 sh-$8.4M
- Redmile GroupTrimmed · -218,200 sh-$7.1M
STOK 13F holders ranked 1–100 of 198
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | BlackRock#1 · 5,877,357 sh | 5,877,357 | $192.3M | <0.01% | +9.1% |
| 2 | RTW INVESTMENTS#2 · 5,623,525 sh | 5,623,525 | $184.0M | 1.57% | 0.0% |
| 3 | FMR#3 · 5,313,100 sh | 5,313,100 | $173.8M | <0.01% | -1.3% |
| 4 | Lynx1 Capital Management#4 · 4,038,404 sh | 4,038,404 | $132.1M | 26.03% | -15.2% |
| 5 | Redmile Group#5 · 3,945,920 sh | 3,945,920 | $129.1M | 8.67% | -5.2% |
| 6 | WELLINGTON MANAGEMENT GROUP LLP#6 · 3,519,301 sh | 3,519,301 | $115.2M | 0.02% | +13.7% |
| 7 | MORGAN STANLEY#7 · 3,452,795 sh | 3,452,795 | $113.0M | <0.01% | +0.9% |
| 8 | BAKER BROS. ADVISORS#8 · 3,336,697 sh | 3,336,697 | $109.2M | 0.55% | 0.0% |
| 9 | TORONTO DOMINION BANK#9 · 3,173,258 sh | 3,173,258 | $103.8M | 0.12% | 0.0% |
| 10 | STATE STREET#10 · 2,852,240 sh | 2,852,240 | $93.3M | <0.01% | +25.3% |
| 11 | PRICE T ROWE ASSOCIATES#11 · 2,661,739 sh | 2,661,739 | $87.1M | <0.01% | +37.6% |
| 12 | VANGUARD CAPITAL MANAGEMENT#12 · 2,586,937 sh | 2,586,937 | $84.6M | <0.01% | +9.8% |
| 13 | BVF#13 · 2,547,557 sh | 2,547,557 | $83.4M | 2.13% | 0.0% |
| 14 | T. Rowe Price Investment Management#14 · 2,415,139 sh | 2,415,139 | $79.0M | 0.05% | +862.5% |
| 15 | Siren, L.L.C.#15 · 1,995,347 sh | 1,995,347 | $65.3M | 1.32% | 0.0% |
| 16 | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)#16 · 1,823,500 sh | 1,823,500 | $59.7M | 0.62% | 0.0% |
| 17 | Jupiter Topco#17 · 1,814,408 sh | 1,814,408 | $59.4M | 0.02% | — |
| 18 | GEODE CAPITAL MANAGEMENT#18 · 1,524,309 sh | 1,524,309 | $49.9M | <0.01% | +15.3% |
| 19 | Assenagon Asset Management S.A.#19 · 1,128,388 sh | 1,128,388 | $36.9M | — | +24.4% |
| 20 | DIMENSIONAL FUND ADVISORS#20 · 1,013,911 sh | 1,013,911 | $33.2M | <0.01% | +2.4% |
| 21 | Polar Capital Plc#21 · 833,716 sh | 833,716 | $27.3M | 0.06% | -26.4% |
| 22 | EcoR1 Capital#22 · 735,000 sh | 735,000 | $24.0M | 1.17% | +635.0% |
| 23 | MPM BioImpact#23 · 723,314 sh | 723,314 | $23.7M | 1.44% | -5.7% |
| 24 | Opaleye Management#24 · 700,000 sh | 700,000 | $22.9M | 2.07% | 0.0% |
| 25 | GOLDMAN SACHS GROUP#25 · 575,344 sh | 575,344 | $18.8M | <0.01% | -30.7% |
| 26 | VANGUARD PORTFOLIO MANAGEMENT#26 · 566,993 sh | 566,993 | $18.6M | <0.01% | +22.5% |
| 27 | BAILLIE GIFFORD#27 · 517,275 sh | 517,275 | $16.9M | 0.02% | -10.1% |
| 28 | NORTHERN#28 · 500,124 sh | 500,124 | $16.4M | <0.01% | +15.9% |
| 29 | Troluce Capital Advisors#29 · 496,416 sh | 496,416 | $16.2M | 1.67% | -24.0% |
| 30 | FIRST ADVISORS#30 · 490,913 sh | 490,913 | $16.1M | <0.01% | +200.3% |
| 31 | CITADEL ADVISORS#31 · 489,301 sh | 489,301 | $16.0M | <0.01% | +297.7% |
| 32 | Candriam S.C.A.#32 · 480,136 sh | 480,136 | $15.7M | 0.07% | -4.4% |
| 33 | CHARLES SCHWAB INVESTMENT MANAGEMENT#33 · 467,012 sh | 467,012 | $15.3M | <0.01% | +6.8% |
| 34 | Granahan Investment Management#34 · 461,608 sh | 461,608 | $15.1M | 0.54% | +37.6% |
| 35 | Erste Asset Management GmbH#35 · 428,381 sh | 428,381 | $13.9M | 0.11% | -4.0% |
| 36 | VANGUARD FIDUCIARY#36 · 402,503 sh | 402,503 | $13.2M | <0.01% | +12.8% |
| 37 | Parkman Healthcare Partners#37 · 355,443 sh | 355,443 | $11.6M | 1.19% | +5.6% |
| 38 | Artisan Partners Limited Partnership#38 · 355,153 sh | 355,153 | $11.6M | 0.02% | +12.6% |
| 39 | JANE STREET GROUP#39 · 331,701 sh | 331,701 | $10.9M | <0.01% | +415.5% |
| 40 | TANG CAPITAL MANAGEMENT#40 · 300,000 sh | 300,000 | $9.8M | 0.45% | -40.0% |
| 41 | MILLENNIUM MANAGEMENT#41 · 261,028 sh | 261,028 | $8.5M | <0.01% | -44.7% |
| 42 | BANK OF AMERICA#42 · 259,708 sh | 259,708 | $8.5M | <0.01% | -52.2% |
| 43 | JPMORGAN CHASE#43 · 259,352 sh | 259,352 | $8.5M | <0.01% | -2.3% |
| 44 | UBS Group AG#44 · 207,112 sh | 207,112 | $6.8M | <0.01% | +30.8% |
| 45 | Birchview Capital#45 · 178,110 sh | 178,110 | $5.8M | 2.73% | -15.2% |
| 46 | Bank of New York Mellon#46 · 164,273 sh | 164,273 | $5.4M | <0.01% | +14.6% |
| 47 | NORGES BANK#47 · 163,200 sh | 163,200 | $5.3M | <0.01% | — |
| 48 | FRANKLIN RESOURCES#48 · 146,395 sh | 146,395 | $4.8M | <0.01% | +2.5% |
| 49 | DAFNA Capital Management#49 · 130,875 sh | 130,875 | $4.3M | 0.82% | 0.0% |
| 50 | ExodusPoint Capital Management#50 · 129,660 sh | 129,660 | $4.2M | 0.03% | New |
| 51 | Nuveen#51 · 122,877 sh | 122,877 | $4.0M | <0.01% | +13.1% |
| 52 | GILDER GAGNON HOWE#52 · 113,065 sh | 113,065 | $3.7M | 0.04% | +0.4% |
| 53 | Jump Financial#53 · 104,350 sh | 104,350 | $3.4M | 0.03% | New |
| 54 | Schonfeld Strategic Advisors#54 · 102,229 sh | 102,229 | $3.3M | 0.01% | +107.4% |
| 55 | Palo Alto Investors#55 · 84,631 sh | 84,631 | $2.8M | 0.38% | 0.0% |
| 56 | BOOTHBAY FUND MANAGEMENT#56 · 80,968 sh | 80,968 | $2.6M | 0.03% | +71.2% |
| 57 | MIRAE ASSET GLOBAL ETFS Ltd.#57 · 80,522 sh | 80,522 | $2.6M | <0.01% | +137.7% |
| 58 | XTX Topco Ltd#58 · 79,613 sh | 79,613 | $2.6M | 0.03% | +888.5% |
| 59 | RHUMBLINE ADVISERS#59 · 75,931 sh | 75,931 | $2.5M | <0.01% | +12.8% |
| 60 | Swiss National Bank#60 · 74,200 sh | 74,200 | $2.4M | <0.01% | -6.2% |
| 61 | Trexquant Investment#61 · 73,475 sh | 73,475 | $2.4M | 0.01% | New |
| 62 | PRINCIPAL FINANCIAL GROUP#62 · 69,880 sh | 69,880 | $2.3M | <0.01% | +9.3% |
| 63 | CITIGROUP#63 · 69,326 sh | 69,326 | $2.3M | <0.01% | +444.8% |
| 64 | Invesco Ltd.#64 · 67,660 sh | 67,660 | $2.2M | <0.01% | -54.9% |
| 65 | TD ASSET MANAGEMENT#65 · 67,200 sh | 67,200 | $2.2M | <0.01% | -9.7% |
| 66 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#66 · 66,160 sh | 66,160 | $2.2M | <0.01% | -4.4% |
| 67 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#67 · 65,228 sh | 65,228 | $2.1M | <0.01% | +12.1% |
| 68 | Rhenman & Partners Asset Management AB#68 · 64,500 sh | 64,500 | $2.1M | 0.20% | -22.3% |
| 69 | ALPS ADVISORS#69 · 63,010 sh | 63,010 | $2.1M | <0.01% | +35.5% |
| 70 | TWO SIGMA INVESTMENTS#70 · 62,371 sh | 62,371 | $2.0M | <0.01% | New |
| 71 | ALLIANCEBERNSTEIN L.P.#71 · 62,390 sh | 62,390 | $2.0M | <0.01% | +49.2% |
| 72 | HighVista Strategies#72 · 61,316 sh | 61,316 | $2.0M | 0.46% | -2.1% |
| 73 | STATE OF WISCONSIN INVESTMENT BOARD#73 · 60,167 sh | 60,167 | $2.0M | <0.01% | +25.7% |
| 74 | PANAGORA ASSET MANAGEMENT#74 · 58,843 sh | 58,843 | $1.9M | <0.01% | New |
| 75 | D. E. Shaw#75 · 57,847 sh | 57,847 | $1.9M | <0.01% | +15.8% |
| 76 | DEUTSCHE BANK AG\#76 · 57,784 sh | 57,784 | $1.9M | <0.01% | +42.3% |
| 77 | WELLS FARGO & COMPANY#77 · 50,835 sh | 50,835 | $1.7M | <0.01% | +155.9% |
| 78 | Woodline Partners#78 · 50,120 sh | 50,120 | $1.6M | <0.01% | 0.0% |
| 79 | Quantinno Capital Management#79 · 49,928 sh | 49,928 | $1.6M | <0.01% | +410.9% |
| 80 | NEW YORK STATE COMMON RETIREMENT FUND#80 · 49,611 sh | 49,611 | $1.6M | <0.01% | +26.7% |
| 81 | Moran Wealth Management#81 · 47,977 sh | 47,977 | $1.6M | — | +18.3% |
| 82 | VICTORY CAPITAL MANAGEMENT#82 · 44,900 sh | 44,900 | $1.5M | <0.01% | +32.5% |
| 83 | Creative Planning#83 · 44,368 sh | 44,368 | $1.5M | <0.01% | -7.8% |
| 84 | Rafferty Asset Management#84 · 43,742 sh | 43,742 | $1.4M | <0.01% | -27.0% |
| 85 | HUSSMAN STRATEGIC ADVISORS#85 · 42,000 sh | 42,000 | $1.4M | 0.32% | -50.0% |
| 86 | Quadrature Capital Ltd#86 · 41,225 sh | 41,225 | $1.3M | 0.01% | +300.5% |
| 87 | PLATINUM INVESTMENT MANAGEMENT LTD#87 · 40,815 sh | 40,815 | $1.3M | 0.33% | 0.0% |
| 88 | Legal & General Group Plc#88 · 35,705 sh | 35,705 | $1.2M | <0.01% | +11.4% |
| 89 | LOS ANGELES CAPITAL MANAGEMENT#89 · 35,598 sh | 35,598 | $1.2M | <0.01% | +16.8% |
| 90 | SCHRODER INVESTMENT MANAGEMENT GROUP#90 · 34,102 sh | 34,102 | $1.1M | <0.01% | 0.0% |
| 91 | Generali Investments, Management#91 · 33,149 sh | 33,149 | $1.1M | — | +379.6% |
| 92 | MetLife Investment Management#92 · 32,132 sh | 32,132 | $1.1M | <0.01% | +23.1% |
| 93 | Corient Private Wealth#93 · 30,823 sh | 30,823 | $1.0M | <0.01% | New |
| 94 | OMERS ADMINISTRATION#94 · 30,000 sh | 30,000 | $981.6K | <0.01% | -27.7% |
| 95 | Squarepoint Ops#95 · 29,310 sh | 29,310 | $959.0K | <0.01% | New |
| 96 | BNP PARIBAS FINANCIAL MARKETS#96 · 27,012 sh | 27,012 | $883.8K | <0.01% | -51.9% |
| 97 | Vanguard Global Advisers#97 · 26,639 sh | 26,639 | $871.6K | <0.01% | 0.0% |
| 98 | AQR CAPITAL MANAGEMENT#98 · 26,449 sh | 26,449 | $865.4K | <0.01% | -43.1% |
| 99 | GREAT WEST LIFE ASSURANCE#99 · 25,197 sh | 25,197 | $824.0K | <0.01% | +33.8% |
| 100 | VANGUARD ASSET MANAGEMENT, Ltd#100 · 25,114 sh | 25,114 | $821.7K | <0.01% | 0.0% |
Funds that sold out of STOK in Q2 2026 (30)
Held STOK at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Quantedge Capital Pte Ltd78,600 sh | 78,600 | $2.6M |
| Harvest Investment Services62,838 sh | 62,838 | $2.0M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP57,291 sh | 57,291 | $1.9M |
| Informed Momentum52,000 sh | 52,000 | $1.7M |
| Privium Fund Management B.V.50,000 sh | 50,000 | $1.6M |
| Caption Management35,174 sh | 35,174 | $1.1M |
| Blackstone30,579 sh | 30,579 | $995.7K |
| NOMURA26,891 sh | 26,891 | $875.6K |
| CANADA PENSION PLAN INVESTMENT BOARD26,200 sh | 26,200 | $853.1K |
| AMERICAN CENTURY COMPANIES23,397 sh | 23,397 | $761.8K |
| HSBC PLC20,521 sh | 20,521 | $686.0K |
| LEUCADIA NATIONAL16,300 sh | 16,300 | $530.7K |
| Campbell & Investment Adviser15,049 sh | 15,049 | $490.0K |
| Virtu Financial11,042 sh | 11,042 | $360.0K |
| AVIVA PLC9,272 sh | 9,272 | $301.9K |
| FARALLON CAPITAL MANAGEMENT9,000 sh | 9,000 | $293.0K |
| ACADIAN ASSET MANAGEMENT8,759 sh | 8,759 | $284.0K |
| STRS OHIO7,000 sh | 7,000 | $227.9K |
| Swiss Life Asset Management Ltd6,544 sh | 6,544 | $213.1K |
| Western Wealth Management1,700 sh | 1,700 | $55.4K |
| Cygnus Capital Advisors1,500 sh | 1,500 | $49.0K |
| VALLEY NATIONAL ADVISERS750 sh | 750 | $24.0K |
| LRI Investments146 sh | 146 | $4.8K |
| SIMPLEX TRADING130 sh | 130 | $4.2K |
| Rachor Investment Advisory Services37 sh | 37 | $1.2K |
| Root Financial Partners23 sh | 23 | $749.00 |
| Parallel Advisors13 sh | 13 | $423.00 |
| MAI Capital Management3 sh | 3 | $98.00 |
| TWIN PEAKS WEALTH ADVISORS3 sh | 3 | $98.00 |
| Keating Financial Advisory Services1 sh | 1 | $33.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.