SOLENO THERAPEUTICS INC (SLNO) — Institutional Holders, Q1 2026

227 institutional investment managers reported a SLNO position on SEC Form 13F-HR for the quarter ended March 31, 2026, with a combined reported value of $1.9B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← SLNO stock profile

SLNO in Q1 2026: what funds did

Funds that filed a 13F for both Q4 2025 and Q1 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

Added to

Trimmed

Sold out

Biggest buyers

Khrom Capital ManagementNew · +1,511,481 sh+$50.6M
WELLINGTON MANAGEMENT GROUP LLPAdded · +1,103,982 sh+$37.0M
PRICE T ROWE ASSOCIATESAdded · +965,822 sh+$32.3M
Vestal Point CapitalNew · +730,000 sh+$24.4M
Polar Capital PlcAdded · +561,926 sh+$18.8M

Biggest sellers

JANUS HENDERSON GROUP PLCTrimmed · -7,030,519 sh-$235.4M
FMRTrimmed · -2,290,894 sh-$76.7M
Invesco Ltd.Trimmed · -830,205 sh-$27.8M
MILLENNIUM MANAGEMENTTrimmed · -629,808 sh-$21.1M
Avoro Capital AdvisorsTrimmed · -600,000 sh-$20.1M

SLNO 13F holders ranked 1–100 of 227

Institutional investors reporting a position in SOLENO THERAPEUTICS INC on SEC Form 13F-HR for Q1 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q4 2025
1	FMR#1 · 5,788,410 sh	5,788,410	$193.8M	—	-28.4%
2	WELLINGTON MANAGEMENT GROUP LLP#2 · 4,426,781 sh	4,426,781	$148.2M	—	+33.2%
3	BlackRock#3 · 3,742,774 sh	3,742,774	$125.3M	—	-3.3%
4	STATE STREET#4 · 2,680,802 sh	2,680,802	$89.8M	—	+1.2%
5	Avoro Capital Advisors#5 · 2,300,000 sh	2,300,000	$77.0M	—	-20.7%
6	VANGUARD CAPITAL MANAGEMENT#6 · 2,153,218 sh	2,153,218	$72.1M	—	—
7	Nantahala Capital Management#7 · 1,744,124 sh	1,744,124	$58.4M	—	+32.7%
8	Polar Capital Plc#8 · 1,698,855 sh	1,698,855	$56.9M	—	+49.4%
9	Khrom Capital Management#9 · 1,511,481 sh	1,511,481	$50.6M	—	New
10	GEODE CAPITAL MANAGEMENT#10 · 1,237,550 sh	1,237,550	$41.4M	—	+6.4%
11	Woodline Partners#11 · 1,112,104 sh	1,112,104	$37.2M	—	0.0%
12	Deep Track Capital#12 · 1,078,710 sh	1,078,710	$36.1M	—	+7.9%
13	PRICE T ROWE ASSOCIATES#13 · 1,025,937 sh	1,025,937	$34.4M	—	+1606.6%
14	BRAIDWELL#14 · 959,259 sh	959,259	$32.1M	—	-19.2%
15	READYSTATE ASSET MANAGEMENT#15 · 952,165 sh	952,165	$31.9M	—	+8.9%
16	FRANKLIN RESOURCES#16 · 835,178 sh	835,178	$28.0M	—	+1.4%
17	Vestal Point Capital#17 · 730,000 sh	730,000	$24.4M	—	New
18	Commodore Capital#18 · 652,432 sh	652,432	$21.8M	—	-45.6%
19	Hood River Capital Management#19 · 623,421 sh	623,421	$20.9M	—	+0.9%
20	Pictet Asset Management Holding SA#20 · 616,217 sh	616,217	$20.6M	—	-1.3%
21	MILLENNIUM MANAGEMENT#21 · 606,513 sh	606,513	$20.3M	—	-50.9%
22	SCHRODER INVESTMENT MANAGEMENT GROUP#22 · 648,827 sh	648,827	$19.8M	—	+44.2%
23	Catalio Capital Management#23 · 577,808 sh	577,808	$19.3M	—	+60.4%
24	KINGDON CAPITAL MANAGEMENT, L.L.C.#24 · 575,000 sh	575,000	$19.3M	—	+43.8%
25	Kynam Capital Management#25 · 560,000 sh	560,000	$18.7M	—	New
26	SUSQUEHANNA INTERNATIONAL GROUP, LLP#26 · 549,877 sh	549,877	$18.4M	—	+125.0%
27	Qube Research & Technologies Ltd#27 · 483,884 sh	483,884	$16.2M	—	+68.4%
28	VANGUARD PORTFOLIO MANAGEMENT#28 · 477,321 sh	477,321	$16.0M	—	—
29	RENAISSANCE TECHNOLOGIES#29 · 447,300 sh	447,300	$15.0M	—	New
30	BANK OF AMERICA#30 · 439,902 sh	439,902	$14.7M	—	+2632.7%
31	BNP PARIBAS FINANCIAL MARKETS#31 · 432,535 sh	432,535	$14.5M	—	+103.2%
32	Caption Management#32 · 420,143 sh	420,143	$14.1M	—	+898.0%
33	CHARLES SCHWAB INVESTMENT MANAGEMENT#33 · 405,910 sh	405,910	$13.6M	—	+1.2%
34	NORTHERN#34 · 393,523 sh	393,523	$13.2M	—	+7.7%
35	CITADEL ADVISORS#35 · 386,545 sh	386,545	$12.9M	—	+25.2%
36	GOLDMAN SACHS GROUP#36 · 385,798 sh	385,798	$12.9M	—	-56.4%
37	Ikarian Capital#37 · 344,123 sh	344,123	$11.5M	—	+400.0%
38	VANGUARD FIDUCIARY#38 · 342,758 sh	342,758	$11.5M	—	—
39	Integral Health Asset Management#39 · 325,000 sh	325,000	$10.9M	—	0.0%
40	Vivo Capital#40 · 294,909 sh	294,909	$9.9M	—	-67.0%
41	abrdn plc#41 · 287,456 sh	287,456	$9.6M	—	0.0%
42	Candriam S.C.A.#42 · 281,620 sh	281,620	$9.4M	—	New
43	Bank of New York Mellon#43 · 277,851 sh	277,851	$9.3M	—	-55.3%
44	EMERALD ADVISERS#44 · 274,138 sh	274,138	$9.2M	—	-33.6%
45	Penn Capital Management Company#45 · 268,785 sh	268,785	$9.0M	—	-2.5%
46	Rock Springs Capital Management#46 · 257,253 sh	257,253	$8.6M	—	+4.1%
47	Logos Global Management#47 · 250,000 sh	250,000	$8.4M	—	-16.7%
48	PFM Health Sciences#48 · 248,180 sh	248,180	$8.3M	—	+0.1%
49	MORGAN STANLEY#49 · 242,262 sh	242,262	$8.1M	—	-15.8%
50	UBS Group AG#50 · 225,147 sh	225,147	$7.5M	—	+32.8%
51	Trexquant Investment#51 · 221,928 sh	221,928	$7.4M	—	+67.0%
52	MARSHALL WACE, LLP#52 · 221,214 sh	221,214	$7.4M	—	+3254.3%
53	Alyeska Investment Group, L.P.#53 · 217,500 sh	217,500	$7.3M	—	0.0%
54	SPHERA FUNDS MANAGEMENT LTD.#54 · 216,281 sh	216,281	$7.2M	—	+58.7%
55	RICE HALL JAMES & ASSOCIATES#55 · 206,147 sh	206,147	$6.9M	—	New
56	Hudson Bay Capital Management#56 · 203,291 sh	203,291	$6.8M	—	New
57	EMERALD MUTUAL FUND ADVISERS#57 · 200,727 sh	200,727	$6.7M	—	-13.7%
58	National Philanthropic#58 · 200,000 sh	200,000	$6.7M	—	+187.6%
59	Ally Bridge Group (NY)#59 · 200,000 sh	200,000	$6.7M	—	+19.0%
60	Boxer Capital Management#60 · 200,000 sh	200,000	$6.7M	—	New
61	SEB Asset Management AB#61 · 187,475 sh	187,475	$6.3M	—	—
62	Squarepoint Ops#62 · 185,337 sh	185,337	$6.2M	—	-60.5%
63	NEW YORK STATE COMMON RETIREMENT FUND#63 · 185,317 sh	185,317	$6.2M	—	0.0%
64	Buckley Capital Advisors#64 · 181,750 sh	181,750	$6.1M	—	+21.9%
65	HSBC PLC#65 · 174,204 sh	174,204	$5.8M	—	New
66	HighVista Strategies#66 · 165,227 sh	165,227	$5.5M	—	+22.3%
67	NICOLET BANKSHARES#67 · 156,766 sh	156,766	$5.2M	—	New
68	DEUTSCHE BANK AG\#68 · 148,374 sh	148,374	$5.0M	—	+4.5%
69	JANUS HENDERSON GROUP PLC#69 · 147,835 sh	147,835	$4.9M	<0.01%	-97.9%
70	Brevan Howard Capital Management#70 · 135,621 sh	135,621	$4.5M	—	-8.2%
71	Deeter Investments LLP#71 · 129,500 sh	129,500	$4.3M	—	New
72	NAN FUNG TRINITY (HK) Ltd#72 · 126,050 sh	126,050	$4.2M	—	+1.8%
73	BOOTHBAY FUND MANAGEMENT#73 · 124,519 sh	124,519	$4.2M	—	+183.9%
74	Seven Fleet Capital Management#74 · 115,770 sh	115,770	$3.9M	—	-11.0%
75	Granahan Investment Management#75 · 114,825 sh	114,825	$3.8M	—	-16.5%
76	Nuveen#76 · 104,738 sh	104,738	$3.5M	—	+4.1%
77	TFG Asset Management GP Ltd#77 · 102,125 sh	102,125	$3.4M	—	New
78	Centiva Capital#78 · 101,234 sh	101,234	$3.4M	—	-14.8%
79	STATE OF WISCONSIN INVESTMENT BOARD#79 · 90,907 sh	90,907	$3.0M	—	+25.4%
80	Swiss National Bank#80 · 90,300 sh	90,300	$3.0M	—	+1.3%
81	XTX Topco Ltd#81 · 85,680 sh	85,680	$2.9M	—	+136.1%
82	MUTUAL OF AMERICA CAPITAL MANAGEMENT#82 · 82,834 sh	82,834	$2.8M	—	-0.4%
83	Rafferty Asset Management#83 · 79,622 sh	79,622	$2.7M	—	-16.7%
84	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#84 · 71,986 sh	71,986	$2.4M	—	-0.5%
85	Artia Global Partners#85 · 68,490 sh	68,490	$2.3M	—	-87.2%
86	HealthInvest Partners AB#86 · 90,184 sh	90,184	$2.2M	—	+43.8%
87	SEI INVESTMENTS#87 · 62,946 sh	62,946	$2.1M	—	-0.7%
88	Exome Asset Management#88 · 61,673 sh	61,673	$2.1M	—	New
89	KVP Capital Advisors#89 · 59,700 sh	59,700	$2.0M	—	0.0%
90	ALLIANCEBERNSTEIN L.P.#90 · 43,090 sh	43,090	$2.0M	—	+1.9%
91	RHUMBLINE ADVISERS#91 · 59,285 sh	59,285	$2.0M	—	+7.7%
92	Russell Investments Group, Ltd.#92 · 58,692 sh	58,692	$2.0M	—	+25.7%
93	Diametric Capital#93 · 57,832 sh	57,832	$1.9M	—	+84.6%
94	BNP Paribas Asset Management Holding S.A.#94 · 57,828 sh	57,828	$1.9M	—	+48.4%
95	CITIGROUP#95 · 56,656 sh	56,656	$1.9M	—	+63.4%
96	SummitTX Capital, L.P.#96 · 56,585 sh	56,585	$1.9M	—	-73.3%
97	TUDOR INVESTMENT ET AL#97 · 56,118 sh	56,118	$1.9M	—	New
98	BARCLAYS PLC#98 · 54,219 sh	54,219	$1.8M	—	-65.6%
99	DV Trading#99 · 54,000 sh	54,000	$1.8M	—	0.0%
100	Engineers Gate Manager#100 · 49,145 sh	49,145	$1.6M	—	-70.7%

Funds that sold out of SLNO in Q1 2026 (61)

Held SLNO at the end of Q4 2025 and filed a Q1 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held SLNO in Q4 2025 and reported no position in Q1 2026.
Institution	Shares sold	Value in Q4 2025
GREAT POINT PARTNERS400,000 sh	400,000	$18.5M
Assenagon Asset Management S.A.384,166 sh	384,166	$17.8M
BALYASNY ASSET MANAGEMENT L.P.227,751 sh	227,751	$10.5M
Skandinaviska Enskilda Banken AB (publ)187,475 sh	187,475	$8.7M
Clark Capital Management Group180,250 sh	180,250	$8.3M
Capital World Investors145,522 sh	145,522	$6.7M
Eagle Health Investments135,100 sh	135,100	$6.3M
ROYCE & ASSOCIATES129,043 sh	129,043	$6.0M
FRONTIER CAPITAL MANAGEMENT119,695 sh	119,695	$5.5M
PEREGRINE CAPITAL MANAGEMENT119,564 sh	119,564	$5.5M
SILVERARC CAPITAL MANAGEMENT117,485 sh	117,485	$5.4M
Jump Financial54,487 sh	54,487	$2.5M
NOMURA ASSET MANAGEMENT INTERNATIONAL33,155 sh	33,155	$1.5M
LEUCADIA NATIONAL29,304 sh	29,304	$1.4M
Aquatic Capital Management28,572 sh	28,572	$1.3M
DIADEMA PARTNERS26,892 sh	26,892	$1.2M
AWM Investment Company20,000 sh	20,000	$926.0K
TD ASSET MANAGEMENT18,622 sh	18,622	$862.2K
Quantitative Investment Management17,581 sh	17,581	$814.0K
Atom Investors17,550 sh	17,550	$812.6K
Walleye Capital16,983 sh	16,983	$786.3K
Magnetar Financial13,946 sh	13,946	$645.7K
Jackson Creek Investment Advisors13,760 sh	13,760	$637.0K
AlphaGrep UK Ltd11,809 sh	11,809	$546.8K
VICTORY CAPITAL MANAGEMENT11,732 sh	11,732	$543.2K
Freestone Grove Partners10,258 sh	10,258	$474.9K
Brummer Multi-Strategy AB8,741 sh	8,741	$404.7K
Scientech Research8,126 sh	8,126	$376.2K
LPL Financial7,720 sh	7,720	$357.4K
Persistent Asset Partners Ltd7,416 sh	7,416	$343.4K
TEACHER RETIREMENT SYSTEM OF TEXAS6,669 sh	6,669	$308.8K
Integrated Wealth Concepts6,560 sh	6,560	$303.7K
Walleye Trading6,521 sh	6,521	$301.9K
MARTINGALE ASSET MANAGEMENT L P5,810 sh	5,810	$269.0K
Perbak Capital Partners LLP5,767 sh	5,767	$267.0K
EntryPoint Capital5,766 sh	5,766	$267.0K
DLD Asset Management5,000 sh	5,000	$231.5K
FARALLON CAPITAL MANAGEMENT5,000 sh	5,000	$231.5K
CAXTON ASSOCIATES LLP4,959 sh	4,959	$229.6K
Creative Planning4,789 sh	4,789	$221.7K
MML INVESTORS SERVICES4,757 sh	4,757	$220.2K
Shay Capital4,600 sh	4,600	$213.0K
Avanza Fonder AB3,195 sh	3,195	$147.9K
Quantbot Technologies3,118 sh	3,118	$144.4K
Bollard Group2,288 sh	2,288	$106.0K
Empowered Funds1,495 sh	1,495	$69.2K
AMALGAMATED BANK1,467 sh	1,467	$68.0K
T. Rowe Price Investment Management1,106 sh	1,106	$52.0K
State of Wyoming497 sh	497	$23.0K
RICHARDSON FINANCIAL SERVICES436 sh	436	$20.2K
DANSKE BANK A/S400 sh	400	$18.5K
NewEdge Advisors175 sh	175	$8.1K
Pinnacle Wealth Planning Services104 sh	104	$4.8K
SRS Capital Advisors46 sh	46	$2.1K
BELLEVUE ASSET MANAGEMENT31 sh	31	$1.4K
ASSETMARK19 sh	19	$880.00
IFP Advisors12 sh	12	$556.00
Ronald Blue11 sh	11	$509.00
SJS Investment Consulting5 sh	5	$232.00
Essential Partners2 sh	2	$93.00
TFC Financial Management1 sh	1	$47.00

Source: Form 13F-HR filings on SEC EDGAR, Q1 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q4 2025 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.