CYTOKINETICS INC (CYTK) — Institutional Holders, Q2 2026

495 institutional investment managers reported a CYTK position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $13.8B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← CYTK stock profile

CYTK in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

Added to

236

Trimmed

104

Sold out

Biggest buyers

BlackRockAdded · +3,546,351 sh+$302.1M
Avoro Capital AdvisorsAdded · +1,666,666 sh+$142.0M
BANK OF AMERICAAdded · +1,510,273 sh+$128.7M
T. Rowe Price Investment ManagementAdded · +1,194,658 sh+$101.8M
Holocene AdvisorsNew · +1,144,579 sh+$97.5M

Biggest sellers

FMRTrimmed · -5,691,358 sh-$484.8M
Paradigm Biocapital AdvisorsSold out · -1,480,857 sh-$126.2M
WELLINGTON MANAGEMENT GROUP LLPTrimmed · -1,077,719 sh-$91.8M
UBS Group AGTrimmed · -905,990 sh-$77.2M
Logos Global ManagementSold out · -875,000 sh-$74.5M

CYTK 13F holders ranked 1–100 of 495

Institutional investors reporting a position in CYTOKINETICS INC on SEC Form 13F-HR for Q2 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q1 2026
1	BlackRock#1 · 20,094,362 sh	20,094,362	$1.7B	0.03%	+21.4%
2	T. Rowe Price Investment Management#2 · 18,718,498 sh	18,718,498	$1.6B	1.05%	+6.8%
3	WELLINGTON MANAGEMENT GROUP LLP#3 · 10,711,770 sh	10,711,770	$597.0M	0.10%	-18.8%
4	VANGUARD PORTFOLIO MANAGEMENT#4 · 6,711,799 sh	6,711,799	$571.8M	0.03%	+14.9%
5	STATE STREET#5 · 6,494,233 sh	6,494,233	$553.2M	0.02%	+13.0%
6	VANGUARD CAPITAL MANAGEMENT#6 · 6,117,515 sh	6,117,515	$521.2M	0.01%	+11.5%
7	FMR#7 · 6,636,782 sh	6,636,782	$431.4M	0.02%	-71.5%
8	Avoro Capital Advisors#8 · 4,999,999 sh	4,999,999	$425.9M	3.82%	+50.0%
9	BANK OF AMERICA#9 · 15,223,709 sh	15,223,709	$412.9M	0.03%	+83.8%
10	GEODE CAPITAL MANAGEMENT#10 · 3,712,501 sh	3,712,501	$316.3M	0.02%	+15.5%
11	RTW INVESTMENTS#11 · 2,862,003 sh	2,862,003	$243.8M	2.08%	+5.2%
12	Polar Capital Plc#12 · 2,253,649 sh	2,253,649	$192.0M	0.45%	+35.7%
13	PRICE T ROWE ASSOCIATES#13 · 1,958,946 sh	1,958,946	$166.9M	0.02%	+23.6%
14	GOLDMAN SACHS GROUP#14 · 4,956,588 sh	4,956,588	$155.5M	0.01%	+23.4%
15	Capital Research Global Investors#15 · 1,686,625 sh	1,686,625	$143.7M	0.02%	+118.8%
16	NORTHERN#16 · 1,647,345 sh	1,647,345	$140.3M	0.02%	+14.3%
17	JPMORGAN CHASE#17 · 1,738,895 sh	1,738,895	$139.4M	<0.01%	-18.7%
18	MORGAN STANLEY#18 · 6,591,318 sh	6,591,318	$137.3M	<0.01%	+41.3%
19	WILLIAM BLAIR INVESTMENT MANAGEMENT#19 · 1,603,442 sh	1,603,442	$136.6M	0.41%	+47.4%
20	Integral Health Asset Management#20 · 1,600,000 sh	1,600,000	$136.3M	5.38%	0.0%
21	Point72 Asset Management, L.P.#21 · 1,587,712 sh	1,587,712	$135.3M	0.15%	+153.6%
22	CHARLES SCHWAB INVESTMENT MANAGEMENT#22 · 1,565,781 sh	1,565,781	$133.4M	0.02%	+12.1%
23	SUSQUEHANNA INTERNATIONAL GROUP, LLP#23 · 1,549,458 sh	1,549,458	$132.0M	0.01%	+72.4%
24	BALYASNY ASSET MANAGEMENT L.P.#24 · 36,355,676 sh	36,355,676	$121.4M	0.15%	-0.8%
25	PRINCIPAL FINANCIAL GROUP#25 · 1,311,664 sh	1,311,664	$111.7M	0.05%	+20.0%
26	Capital International Investors#26 · 1,305,848 sh	1,305,848	$111.2M	0.02%	-2.5%
27	Invesco Ltd.#27 · 1,235,323 sh	1,235,323	$105.2M	<0.01%	+154.7%
28	ARMISTICE CAPITAL#28 · 1,201,342 sh	1,201,342	$102.3M	1.25%	+57.1%
29	UBS Group AG#29 · 1,171,287 sh	1,171,287	$99.8M	0.01%	-43.6%
30	Pictet Asset Management Holding SA#30 · 1,160,463 sh	1,160,463	$99.0M	0.09%	+54.5%
31	Frazier Life Sciences Management, L.P.#31 · 1,159,879 sh	1,159,879	$98.8M	2.15%	0.0%
32	Bank of New York Mellon#32 · 1,350,697 sh	1,350,697	$98.4M	0.02%	+12.0%
33	Holocene Advisors#33 · 1,144,579 sh	1,144,579	$97.5M	0.22%	New
34	Woodline Partners#34 · 1,100,708 sh	1,100,708	$93.8M	0.29%	+10.0%
35	D. E. Shaw#35 · 1,048,103 sh	1,048,103	$89.3M	0.04%	+48.3%
36	NORGES BANK#36 · 1,015,522 sh	1,015,522	$86.5M	<0.01%	—
37	Royalty Pharma Sub-Manager#37 · 980,392 sh	980,392	$83.5M	34.52%	0.0%
38	NOMURA ASSET MANAGEMENT INTERNATIONAL#38 · 961,815 sh	961,815	$81.9M	0.12%	+1883.8%
39	GW&K Investment Management#39 · 916,107 sh	916,107	$78.0M	0.61%	+85.2%
40	VANGUARD FIDUCIARY#40 · 906,423 sh	906,423	$77.2M	0.02%	+13.4%
41	FRANKLIN RESOURCES#41 · 891,087 sh	891,087	$75.9M	0.02%	+117.5%
42	BNP Paribas Asset Management Holding S.A.#42 · 3,327,810 sh	3,327,810	$74.8M	0.07%	+3.5%
43	Melqart Asset Management (UK) Ltd#43 · 767,525 sh	767,525	$65.4M	6.22%	-9.1%
44	Siren, L.L.C.#44 · 758,952 sh	758,952	$64.7M	1.31%	+23.6%
45	Fisher Asset Management#45 · 743,697 sh	743,697	$63.4M	0.02%	-3.2%
46	Foresite Capital Management IV#46 · 714,695 sh	714,695	$60.9M	20.98%	+42.0%
47	Deep Track Capital#47 · 700,000 sh	700,000	$59.6M	0.87%	-49.1%
48	BNP PARIBAS FINANCIAL MARKETS#48 · 689,077 sh	689,077	$58.7M	0.02%	-19.3%
49	Nuveen#49 · 11,617,185 sh	11,617,185	$57.1M	0.01%	-19.1%
50	Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.#50 · 660,310 sh	660,310	$56.3M	3.08%	0.0%
51	CITADEL ADVISORS#51 · 640,945 sh	640,945	$54.6M	<0.01%	-41.7%
52	TWO SIGMA INVESTMENTS#52 · 16,087,411 sh	16,087,411	$53.8M	0.04%	+14.5%
53	Qube Research & Technologies Ltd#53 · 572,535 sh	572,535	$48.8M	0.05%	-26.5%
54	BROWN ADVISORY#54 · 570,664 sh	570,664	$48.6M	0.08%	-7.2%
55	EVENTIDE ASSET MANAGEMENT#55 · 564,398 sh	564,398	$48.1M	0.64%	+17.8%
56	Affinity Asset Advisors#56 · 550,000 sh	550,000	$46.9M	2.12%	-21.5%
57	MASSACHUSETTS FINANCIAL SERVICES#57 · 549,348 sh	549,348	$46.8M	0.01%	+76.3%
58	FEDERATED HERMES#58 · 538,022 sh	538,022	$45.8M	0.07%	-23.1%
59	First Turn Management#59 · 527,412 sh	527,412	$44.9M	4.81%	+85.9%
60	AMERICAN CENTURY COMPANIES#60 · 518,398 sh	518,398	$44.2M	0.02%	+16.8%
61	Checkpoint Capital L.P.#61 · 475,000 sh	475,000	$40.5M	10.38%	+163.9%
62	Hood River Capital Management#62 · 469,273 sh	469,273	$40.0M	0.29%	New
63	EMERALD ADVISERS#63 · 457,956 sh	457,956	$39.0M	0.92%	+130.3%
64	ADAR1 Capital Management#64 · 457,907 sh	457,907	$39.0M	1.79%	-27.6%
65	AMERIPRISE FINANCIAL#65 · 454,851 sh	454,851	$38.7M	<0.01%	+50.2%
66	MARSHALL WACE, LLP#66 · 451,467 sh	451,467	$38.5M	0.03%	-31.2%
67	Candriam S.C.A.#67 · 443,066 sh	443,066	$37.7M	0.17%	+32.2%
68	RHUMBLINE ADVISERS#68 · 421,799 sh	421,799	$35.9M	0.03%	+14.1%
69	ALLIANCEBERNSTEIN L.P.#69 · 535,993 sh	535,993	$35.3M	0.01%	+16.8%
70	Handelsbanken Fonder AB#70 · 405,000 sh	405,000	$34.5M	0.10%	+63.8%
71	GILDER GAGNON HOWE#71 · 400,245 sh	400,245	$34.1M	0.35%	+20.9%
72	TD ASSET MANAGEMENT#72 · 385,130 sh	385,130	$32.8M	0.03%	-8.5%
73	VOYA INVESTMENT MANAGEMENT#73 · 368,698 sh	368,698	$31.4M	0.03%	+42.1%
74	GSK plc#74 · 340,434 sh	340,434	$29.0M	4.82%	0.0%
75	CITIGROUP#75 · 497,932 sh	497,932	$27.8M	<0.01%	+99.8%
76	E. Ohman J:or Asset Management AB#76 · 304,611 sh	304,611	$25.9M	—	+1.3%
77	Russell Investments Group, Ltd.#77 · 441,566 sh	441,566	$25.9M	0.02%	+40.6%
78	Trails Edge Capital Partners#78 · 288,089 sh	288,089	$24.5M	3.90%	-4.0%
79	BANK OF MONTREAL#79 · 285,688 sh	285,688	$24.3M	<0.01%	+1855.2%
80	EMERALD MUTUAL FUND ADVISERS#80 · 279,769 sh	279,769	$23.8M	0.84%	+106.5%
81	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#81 · 273,031 sh	273,031	$23.3M	<0.01%	+13.5%
82	Polaris Capital Management#82 · 266,900 sh	266,900	$22.7M	—	New
83	SEGALL BRYANT & HAMILL#83 · 257,063 sh	257,063	$21.9M	0.26%	+40.2%
84	Alyeska Investment Group, L.P.#84 · 250,000 sh	250,000	$21.3M	0.05%	+66.7%
85	ExodusPoint Capital Management#85 · 249,259 sh	249,259	$21.2M	0.14%	+377.3%
86	Capital World Investors#86 · 248,815 sh	248,815	$21.2M	<0.01%	+2.8%
87	Jupiter Topco#87 · 244,417 sh	244,417	$20.8M	<0.01%	—
88	Walleye Capital#88 · 239,728 sh	239,728	$20.4M	0.07%	New
89	Sarissa Capital Management#89 · 228,623 sh	228,623	$19.5M	10.95%	0.0%
90	Swiss National Bank#90 · 222,400 sh	222,400	$18.9M	<0.01%	-3.2%
91	SPHERA FUNDS MANAGEMENT LTD.#91 · 219,987 sh	219,987	$18.7M	2.44%	+452.5%
92	DEUTSCHE BANK AG\#92 · 216,540 sh	216,540	$18.4M	<0.01%	+15.7%
93	PRUDENTIAL FINANCIAL#93 · 214,535 sh	214,535	$18.3M	0.02%	+261.0%
94	BAKER BROS. ADVISORS#94 · 211,267 sh	211,267	$18.0M	0.09%	New
95	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM#95 · 211,052 sh	211,052	$18.0M	0.01%	+6.3%
96	Nicholas Investment Partners#96 · 209,071 sh	209,071	$17.8M	1.00%	+199.3%
97	PINNACLE ASSOCIATES LTD#97 · 202,440 sh	202,440	$17.2M	—	+14.3%
98	Mirador Capital Partners#98 · 202,370 sh	202,370	$17.2M	—	-0.1%
99	Tri Locum Partners#99 · 194,000 sh	194,000	$16.5M	2.03%	New
100	PFM Health Sciences#100 · 191,686 sh	191,686	$16.3M	1.40%	New

Funds that sold out of CYTK in Q2 2026 (48)

Held CYTK at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held CYTK in Q1 2026 and reported no position in Q2 2026.
Institution	Shares sold	Value in Q1 2026
Paradigm Biocapital Advisors1,480,857 sh	1,480,857	$97.6M
Logos Global Management875,000 sh	875,000	$57.7M
MPM BioImpact500,000 sh	500,000	$33.0M
GROUP ONE TRADING, L.P.363,997 sh	363,997	$24.0M
Vestal Point Capital300,000 sh	300,000	$19.8M
Ikarian Capital283,572 sh	283,572	$18.7M
Caption Management245,000 sh	245,000	$16.1M
Catalio Capital Management215,501 sh	215,501	$14.2M
Monashee Investment Management100,000 sh	100,000	$6.6M
Sofinnova Ventures91,791 sh	91,791	$6.0M
SILVERARC CAPITAL MANAGEMENT71,203 sh	71,203	$4.7M
Tyro Capital Management64,666 sh	64,666	$4.3M
AIGEN INVESTMENT MANAGEMENT31,216 sh	31,216	$2.1M
Knott David M Jr23,644 sh	23,644	$1.6M
Edgestream Partners, L.P.23,491 sh	23,491	$1.5M
Daiwa Securities Group22,200 sh	22,200	$1.5M
PRELUDE CAPITAL MANAGEMENT21,813 sh	21,813	$1.4M
SANDERS MORRIS HARRIS21,505 sh	21,505	$1.4M
Atom Investors20,350 sh	20,350	$1.3M
Marex Group plc11,301 sh	11,301	$744.8K
Creek Drive Management Group10,000 sh	10,000	$659.1K
Qsemble Capital Management8,810 sh	8,810	$580.7K
PSP Research8,300 sh	8,300	$547.1K
VARCOV7,805 sh	7,805	$514.4K
SIG BROKERAGE6,011 sh	6,011	$396.2K
Graham Capital Management, L.P.4,414 sh	4,414	$290.9K
Kestra Advisory Services4,115 sh	4,115	$271.2K
Shay Capital3,275 sh	3,275	$215.9K
GTS SECURITIES3,206 sh	3,206	$211.3K
Root Financial Partners1,515 sh	1,515	$99.9K
Western Wealth Management800 sh	800	$52.7K
Advisory Services Network557 sh	557	$36.7K
J.Safra Asset Management309 sh	309	$20.4K
Tradewinds Capital Management215 sh	215	$14.2K
MAI Capital Management201 sh	201	$13.2K
Rakuten Securities170 sh	170	$11.2K
Leonteq Securities AG160 sh	160	$10.5K
TWIN PEAKS WEALTH ADVISORS152 sh	152	$10.0K
WOLVERINE ASSET MANAGEMENT120 sh	120	$7.9K
Richardson Capital Management38 sh	38	$2.5K
Rachor Investment Advisory Services36 sh	36	$2.4K
CULLEN/FROST BANKERS35 sh	35	$2.3K
Golden State Equity Partners30 sh	30	$2.0K
Annis Gardner Whiting Capital Advisors17 sh	17	$1.1K
Wealth Preservation Advisors9 sh	9	$593.00
Vermillion Wealth Management7 sh	7	$461.00
Ronald Blue3 sh	3	$198.00
Elequin Securities75 sh	75	—

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.