How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to Patient Square

13F Portfolio OverlapQ1 2026Patient Square portfolio →

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Most similar hedge funds by 13F overlap

Patient Square Capital LP is an institutional investor managing $564M across 29 U.S. equity positions as of Q1 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to Patient Square are First Turn ,, Davern Partners,, Affinity Asset Advisors,, with shared positions in $INSM, $COGT, $MIRM, $ROIV, $ABVX, $XENE. The full ranking of 25 similar funds is below.

#1First Turn Management, LLCActive

Substantial overlap · 10 shared positions

$INSM $COGT $MIRM $ROIV $ABVX $XENE

$895M

33 positions

#2Davern Capital Partners, LPActive

Substantial overlap · 5 shared positions

$ROIV $ARGX $INSM $LEGN $ABVX

$365M

17 positions

#3Affinity Asset Advisors, LLCActive

Notable overlap · 9 shared positions

$ROIV $INSM $ABVX $XENE $COGT $DNTH

$1.9B

105 positions

#4Rock Springs Capital Management LPActive

Notable overlap · 8 shared positions

$ARGX $MIRM $INSM $XENE $KYMR $COGT

$1.7B

100 positions

#5Octagon Capital Advisors LPActive

Notable overlap · 10 shared positions

$COGT $MIRM $ABVX $XENE $KYMR $DNTH

$904M

29 positions

#6Artia Global Partners LPActive

Notable overlap · 9 shared positions

$ARGX $INSM $ABVX $EYPT $DNTH $BLTE

$499M

50 positions

#7Commodore Capital LPActive

Notable overlap · 10 shared positions

$COGT $PHVS $XENE $EYPT $KYMR $ELVN

$1.7B

36 positions

#8Seven Fleet Capital Management LPActive

Notable overlap · 10 shared positions

$COGT $PHVS $ABVX $ROIV $DNTH $ELVN

$315M

114 positions

#9StemPoint Capital LPActive

Notable overlap · 11 shared positions

$ABVX $ROIV $EYPT $ARQT $XENE $DNTH

$515M

82 positions

#10Darwin Global Management, Ltd.Active

Notable overlap · 5 shared positions

$ROIV $INSM $BLTE $ABVX $DNTH

$3.8B

6 positions

#11RTW INVESTMENTS, LPActive

Notable overlap · 6 shared positions

$ARGX $INSM $COGT $CELC $BLTE $SYRE

$10.0B

88 positions

#12BAKER BROS. ADVISORS LPSmart money

Notable overlap · 10 shared positions

$INSM $ONC $CELC $KYMR $ROIV $ABVX

$17.4B

84 positions

#13Sofinnova Ventures IncActive

Notable overlap · 8 shared positions

$COGT $INSM $CELC $NKTR $PHVS $XENE

$2.6B

74 positions

#14DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)Active

Notable overlap · 7 shared positions

$COGT $MIRM $CELC $LEGN $XENE $PHVS

$8.5B

82 positions

#15ADAR1 Capital Management, LLCPassive

Notable overlap · 8 shared positions

$ROIV $ABVX $DBVT $CTMX $XENE $ELVN

$1.7B

310 positions

#16HealthInvest Partners ABActive

Notable overlap · 6 shared positions

$ONC $MIRM $INSM $CELC $ABVX $SYRE

$310M

39 positions

#17Siren, L.L.C.Active

Notable overlap · 8 shared positions

$ONC $XENE $COGT $KYMR $DBVT $ELVN

$3.6B

100 positions

#18SILVERARC CAPITAL MANAGEMENT, LLCActive

Notable overlap · 7 shared positions

$COGT $ABVX $CELC $DNTH $XENE $INSM

$980M

73 positions

#19Paradigm Biocapital Advisors LPActive

Notable overlap · 7 shared positions

$INSM $BLTE $ABVX $MIRM $EYPT $ASMB

$4.9B

35 positions

#20TCG Crossover Management, LLCActive

Notable overlap · 6 shared positions

$COGT $MIRM $ABVX $DNTH $CATX $SYRE

$3.5B

49 positions

#21Avoro Capital Advisors LLCActive

Notable overlap · 5 shared positions

$ARGX $XENE $CELC $KYMR $DFTX

$10.2B

32 positions

#22Saturn V Capital Management LPActive

Notable overlap · 4 shared positions

$COGT $PHVS $ABVX $CELC

$552M

21 positions

#23Eagle Health Investments LPActive

Notable overlap · 3 shared positions

$ARGX $INSM $KYMR

$572M

28 positions

#24Cormorant Asset Management, LPActive

Notable overlap · 8 shared positions

$ABVX $EYPT $INSM $PHVS $DNTH $ROIV

$2.0B

47 positions

#25MPM BioImpact LLCActive

Notable overlap · 7 shared positions

$DBVT $XENE $DNTH $ARQT $BLTE $ABVX

$1.3B

41 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.