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Octagon Capital Advisors LP

Institutional InvestorSimilar funds →SEC EDGAR: CIK 1839435
Institutional-grade research for retail investors

Sector Allocation

  • Healthcare99.2%$1.1B
  • Other0.8%$9.0M

AUM History

13fpro.ai/research/fund/octagon-capital-advisors-lp-1839435

Largest positions — Q2 2026

Top 20 stock positions. Options are left out: 13F reports them at the underlying's value.

13fpro.ai/research/fund/octagon-capital-advisors-lp-1839435

Octagon Capital Advisors LP 13F holdings — Q2 2026

$1.1B portfolio (+23.1% QoQ) · 27 holdings · Q2 2026 13F · top 10 are 80% of the stock portfolio

Includes $23.0M of put/call options ($0 puts, $23.0M calls), which 13F rules report at the value of the underlying shares, not the premium at risk. Stocks alone: $1.1B. Weights use the stock portfolio.

All holdings — Octagon Capital Advisors LP (Q2 2026)

27 disclosed positions from the Form 13F-HR on SEC EDGAR, with quarter-over-quarter share changes. Largest by value first; the ten above are not repeated.

Company
AKTS$AKTSAktis Oncology, Inc.$31.0M—
XENE$XENEXenon Pharmaceuticals Inc.$29.6M—
ERAS$ERASCALLErasca, Inc.$23.0MNew
PALI$PALIPALISADE BIO, INC.$21.5M—
OCUL$OCULOCULAR THERAPEUTIX, INC$20.4M-34%
IRON$IRONDisc Medicine, Inc.$19.7M—
SMMT$SMMTSummit Therapeutics Inc.$18.2MNew
PHVS$PHVSPharvaris N.V.$15.8M+177%
ANL$ANLAdlai Nortye Group Ltd.adr$10.7MNew
DTIL$DTILPRECISION BIOSCIENCES INC$10.6M-40%
DBVT$DBVTDBV Technologies S.A.adr$9.4M—
— FAETH THERAPEUTICS INC - COM NEW$9.0MNew
GYRE$GYREGYRE THERAPEUTICS, INC.$6.3MNew
TRVI$TRVITrevi Therapeutics, Inc.$5.9M-79%
UNCY$UNCYUnicycive Therapeutics, Inc.$4.7M—

What changed in Q2 2026

Against the previous quarter's 13F: 5 new, 4 added to, 6 trimmed, 7 sold out. Share-count changes; largest moves by dollar size first.

New positions (5)

  • ERAS$ERASCALLErasca, Inc.$23.0M

    first bought this quarter

  • SMMT$SMMTSummit Therapeutics Inc.$18.2M

    first bought this quarter

  • ANL$ANLAdlai Nortye Group Ltd.$10.7M

    first bought this quarter

  • FAETH THERAPEUTICS INC - COM NEW$9.0M

    first bought this quarter

  • GYRE$GYREGYRE THERAPEUTICS, INC.$6.3M

    first bought this quarter

Added to (4)

  • ABVX$ABVXAbivax S.A.+47%

    now $132.3M · held 5+ qtrs

  • DFTX$DFTXDefinium Therapeutics, Inc.+21%

    now $138.8M · held 2 qtrs, 2 adds in a row

  • PHVS$PHVSPharvaris N.V.+177%

    now $15.8M · held 5+ qtrs

  • TSHA$TSHATaysha Gene Therapies, Inc.+9%

    now $66.0M · held 5+ qtrs

Trimmed (6)

  • TRVI$TRVITrevi Therapeutics, Inc.-79%

    now $5.9M · held 5+ qtrs, 2 trims in a row

  • KYMR$KYMRKymera Therapeutics, Inc.-27%

    now $35.5M · held 5+ qtrs, 2 trims in a row

  • OCUL$OCULOCULAR THERAPEUTIX, INC-34%

    now $20.4M · held 5+ qtrs

  • DNTH$DNTHDianthus Therapeutics, Inc. /DE/-5%

    now $179.5M · held 5+ qtrs, 2 trims in a row

  • DTIL$DTILPRECISION BIOSCIENCES INC-40%

    now $10.6M · held 3 qtrs

  • CNTX$CNTXContext Therapeutics Inc.-42%

    now $1.7M · held 2 qtrs

Sold out (7)

  • CNTA$CNTACentessa Pharmaceuticals plcwas $29.8M

    held 9+ qtrs

  • KALV$KALVKalVista Pharmaceuticals, Inc.was $29.2M

    held 6+ qtrs

  • TERN$TERNTerns Pharmaceuticals, Inc.was $27.9M

    held 1 qtr

  • BBOT$BBOTBridgeBio Oncology Therapeutics, Inc.was $6.4M

    held 3 qtrs

  • LXEO$LXEOLexeo Therapeutics, Inc.was $6.3M

    held 2 qtrs

  • CATX$CATXPerspective Therapeutics, Inc.was $3.3M

+1 more in the Excel export

Firm AUM (Form ADV): $1.2B as of 2025-12-31 · SEC IAPD

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Holdings by quarter

Every 13F Octagon Capital Advisors LP has filed, 22 earlier quarters. Pick one to see what it held then.

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Q2 2026 13F filed with the SEC on Aug 14, 2026. Prices are closing prices as of Oct 26, 2026.

Average quality of Octagon Capital Advisors's top 20 holdings: 19/100 (our AI quality score, weighted by position size; 9 of the 20 are scored)

Top 10 since filing

-31.6%

Value-weighted move of the 10 largest stock positions

Turnover

13%

Last quarter; 62% over the last 4

Top 10 weight

80%

Share of the stock portfolio in its 10 largest positions

Held 4+ quarters

58%

Share of portfolio value in positions held a year or more

Highest-quality names it owns(among its 100 largest positions)

The 8 highest-scoring companies in this portfolio are a Pro feature.

How these are measured
  • Moves since the quarter-end and since the filing date use our own daily closing prices, from the close on (or just before) each date to the latest close.
  • Turnover is the lesser of shares bought or sold in a quarter, valued at the quarter-end prices in the 13F, divided by the average of the two quarters' stock portfolio values.
  • Quarters held and add/trim streaks count back only through quarters whose filed holdings add up to the filing's own cover-page total (back to Q2 2025 for this fund). A change counts as an add or a trim when the split-adjusted share count moves by more than 1%.
  • Estimate, not the fund's reported cost. For each quarter in the current holding period in which the fund's share count rose (split-adjusted), we take that quarter's average daily close and weight it by the shares added; sales do not change an average cost. Quarters where the stock's price history and the 13F's own implied price disagree by more than 2x are left out.
  • Put and call option rows report the value of the underlying shares, not a position the fund paid for, so they are left out of all of the above.

Portfolio Overview

Octagon Capital Advisors LP disclosed 27 positions worth $1.1B in its Form 13F-HR for Q2 2026 — $1.1B in common stock plus $23.0M of put/call option positions (reported at underlying notional value, not premium at risk), led by $DNTH (Dianthus Therapeutics, Inc. /DE/) at 16.5% of the equity portfolio, followed by $DFTX and $ABVX. During the quarter the fund opened 5 new positions and exited 7 — including a new stake in $ERAS and a full exit from $CNTA. The portfolio is most concentrated in Healthcare (99.2% of disclosed assets). All figures are sourced directly from Octagon Capital Advisors LP’s Form 13F-HR filing with the SEC under CIK 1839435.

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AI-Powered Hedge Fund Analysis: Octagon Capital Advisors LP

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Every holding in Octagon Capital Advisors LP's portfolio is scored on an AI quality ranking built from its SEC filings (ROIC, FCF margin, revenue growth, institutional flow, earnings quality, shareholder dilution, and more). Track accumulation and distribution quarter over quarter, identify conviction positions, and see AI stock analysis for each position — alongside 8,700+ other institutional filers and 2,800+ AI-ranked companies.