SILVERARC CAPITAL MANAGEMENT, LLC

Institutional InvestorSimilar funds →SEC EDGAR: CIK 1816307
Institutional-grade research for retail investors

13F Reported Value

$979.8M

incl. option notional

Equity Holdings

$848.6M

Option Notional

$131.2M

$105.4M puts / $25.8M calls

Holdings

73

Latest Filing

2026-03-31

Filing Quarter

Q1 2026

Portfolio Overview

SILVERARC CAPITAL MANAGEMENT, LLC disclosed 73 positions worth $979.8M in its Form 13F-HR for Q1 2026$848.6M in common stock plus $131.2M of put/call option positions (reported at underlying notional value, not premium at risk), followed by $KALV and $DNTH. During the quarter the fund opened 25 new positions and exited 20 and a full exit from $VRDN. The portfolio is most concentrated in Healthcare (98.5% of disclosed assets). All figures are sourced directly from SILVERARC CAPITAL MANAGEMENT, LLC’s Form 13F-HR filing with the SEC under CIK 1816307.

Sector Allocation

HealthcareOther

AUM History

Top Equity Holdings by Value

Option Positions

13F rules report options at the value of the underlying shares (notional) — not the premium paid or capital at risk. Shown separately from the equity sleeve above.

SPDR SERIES TRUSTPUT$105M notional
$QURECALL$8M notional
$SNDXCALL$7M notional
$CELCCALL$6M notional
$FULCCALL$3M notional
$CMPXCALL$912K notional

Quarterly Activity — Q1 2026

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Top Holdings

AI Quality Scored

Unlock AI quality scores for every holding

32-signal composite ranking on each of SILVERARC CAPITAL MANAGEMENT, LLC's 73 positions.

Showing top 10 of 73 holdings.

Sector Allocation

Healthcare

$836.4M

Other

$12.3M

Full Holdings — SILVERARC CAPITAL MANAGEMENT, LLC (Q1 2026)

All 73 disclosed positions from the latest Form 13F-HR, with quarter-over-quarter share changes and 13F Pro quality scores. Sourced from SEC EDGAR.

#TickerCompanyValueWeightQoQQuality
1SPDR SERIES TRUST$105.4MNEW
2KALV$KALVKalVista Pharmaceuticals, Inc.$57.9M6.8%+19%25.9
3DNTH$DNTHDianthus Therapeutics, Inc. /DE/$54.9M6.5%-13%26.8
4COGT$COGTCogent Biosciences, Inc.$50.6M6.0%+6%
5CELC$CELCCelcuity Inc.$40.9M4.8%-5%
6IMNM$IMNMImmunome Inc.$40.5M4.8%+64%5.8
7KOD$KODKodiak Sciences Inc.$37.8M4.5%-3%
8NUVL$NUVLNuvalent, Inc.$36.4M4.3%+14%
9ABVX$ABVXAbivax S.A.$33.7M4.0%-28%
10GLUE$GLUEMonte Rosa Therapeutics, Inc.$32.9M3.9%+95%18.1
11ERAS$ERASErasca, Inc.$30.0M3.5%+41%
12ASND$ASNDAscendis Pharma A/S$28.5M3.4%+153%41.5
13URGN$URGNUroGen Pharma Ltd.$27.0M3.2%-14%
14RYTM$RYTMRHYTHM PHARMACEUTICALS, INC.$26.6M3.1%+125%30.3
15PRAX$PRAXPraxis Precision Medicines, Inc.$23.1M2.7%-13%
16ZBIO$ZBIOZenas BioPharma, Inc.$22.2M2.6%NEW14.4
17SNDX$SNDXSyndax Pharmaceuticals Inc$20.8M2.5%+38%30
18CNTA$CNTACentessa Pharmaceuticals plc$18.5M2.2%+2%
19SRRK$SRRKScholar Rock Holding Corp$16.7M2.0%NEW
20ALKS$ALKSAlkermes plc.$16.3M1.9%NEW
21ORIC$ORICOric Pharmaceuticals, Inc.$13.9M1.6%-1%
22IRON$IRONDisc Medicine, Inc.$12.5M1.5%NEW
23HELIX ACQUISITION CORP III$12.3M1.4%NEW
24XENE$XENEXenon Pharmaceuticals Inc.$11.5M1.4%NEW12.9
25CGON$CGONCG Oncology, Inc.$11.3M1.3%-54%28
26IMVT$IMVTImmunovant, Inc.$10.3M1.2%NEW
27SYRE$SYRESpyre Therapeutics, Inc.$9.4M1.1%-1%
28BIIB$BIIBBIOGEN INC.$9.3M1.1%-32%65.6
29GH$GHGuardant Health, Inc.$9.1M1.1%+7%36.1
30PCVX$PCVXVaxcyte, Inc.$8.4M1.0%-3%
31QURE$QURECALLuniQure N.V.$8.2M-31%
32SVRA$SVRASavara Inc$7.8M0.9%NEW
33BNTC$BNTCBenitec Biopharma Inc.$7.6M0.9%-2%
34SNDX$SNDXCALLSyndax Pharmaceuticals Inc$7.5MNEW30
35ORKA$ORKAOruka Therapeutics, Inc.$7.4M0.9%NEW
36CGEN$CGENCOMPUGEN LTD$7.1M0.8%-5%
37CELC$CELCCALLCelcuity Inc.$6.2MNEW
38TRVI$TRVITrevi Therapeutics, Inc.$6.1M0.7%-6%
39INSM$INSMINSMED Inc$5.9M0.7%-50%29.4
40VCYT$VCYTVERACYTE, INC.$5.8M0.7%-50%59.5
41CERS$CERSCERUS CORP$5.8M0.7%+13%29.3
42CLDX$CLDXCelldex Therapeutics, Inc.$5.7M0.7%-7%13.2
43CCCC$CCCCC4 Therapeutics, Inc.$5.0M0.6%-4%6.5
44CYTK$CYTKCYTOKINETICS INC$4.7M0.6%NEW28
45CLYM$CLYMClimb Bio, Inc.$4.7M0.6%NEW
46CMPX$CMPXCompass Therapeutics, Inc.$4.5M0.5%-18%
47SRZN$SRZNSurrozen, Inc./DE$4.2M0.5%-8%
48CTNM$CTNMContineum Therapeutics, Inc.$3.9M0.5%-2%
49ZURA$ZURAZura Bio Ltd$3.3M0.4%NEW
50FULC$FULCFulcrum Therapeutics, Inc.$3.2M0.4%+6%
51FULC$FULCCALLFulcrum Therapeutics, Inc.$3.0M+0%
52ABEO$ABEOABEONA THERAPEUTICS INC.$2.9M0.3%+3%44.3
53CAMP$CAMPCamp4 Therapeutics Corp$2.9M0.3%NEW23.3
54ANNX$ANNXAnnexon, Inc.$2.8M0.3%NEW
55ELUT$ELUTELUTIA INC.$2.6M0.3%-9%
56CBIO$CBIOCRESCENT BIOPHARMA, INC.$2.4M0.3%NEW28
57MNPR$MNPRMonopar Therapeutics$2.4M0.3%NEW
58OVID$OVIDOvid Therapeutics Inc.$2.2M0.3%NEW13.1
59NXTC$NXTCNextCure, Inc.$1.9M0.2%+0%
60CMPS$CMPSCOMPASS Pathways plc$1.7M0.2%NEW
61NMRA$NMRANeumora Therapeutics, Inc.$1.6M0.2%NEW
62SION$SIONSionna Therapeutics, Inc.$1.6M0.2%-5%
63TELA$TELATELA Bio, Inc.$1.4M0.2%-15%24.9
64EWTX$EWTXEdgewise Therapeutics, Inc.$1.3M0.2%+1%
65REPL$REPLReplimune Group, Inc.$1.3M0.1%NEW
66GENB$GENBGenerate Biomedicines, Inc.$1.3M0.1%NEW
67CMPX$CMPXCALLCompass Therapeutics, Inc.$911,996NEW
68RADX$RADXRadiopharm Theranostics Ltd$805,8460.1%+0%
69GUTS$GUTSFRACTYL HEALTH, INC.$779,0040.1%-83%
70IBIO$IBIOiBio, Inc.$429,4000.1%+113%
71ADGM$ADGMAdagio Medical Holdings, Inc.$289,7680.0%-51%
72AARD$AARDAardvark Therapeutics, Inc.$126,9890.0%-89%
73RCKT$RCKTROCKET PHARMACEUTICALS, INC.$2,1590.0%+0%

New Positions (25)

PUT SPDR SERIES TRUST$105.4M
ZBIO$ZBIO Zenas BioPharma, Inc.$22.2M
SRRK$SRRK Scholar Rock Holding Corp$16.7M
ALKS$ALKS Alkermes plc.$16.3M
IRON$IRON Disc Medicine, Inc.$12.5M
HELIX ACQUISITION CORP III$12.3M
XENE$XENE Xenon Pharmaceuticals Inc.$11.5M
IMVT$IMVT Immunovant, Inc.$10.3M
SVRA$SVRA Savara Inc$7.8M
SNDX$SNDXCALL Syndax Pharmaceuticals Inc$7.5M
ORKA$ORKA Oruka Therapeutics, Inc.$7.4M
CELC$CELCCALL Celcuity Inc.$6.2M
CYTK$CYTK CYTOKINETICS INC$4.7M
CLYM$CLYM Climb Bio, Inc.$4.7M
ZURA$ZURA Zura Bio Ltd$3.3M

Exited Positions (20)

VRDN$VRDN Viridian Therapeutics, Inc.\DE
PFE$PFE PFIZER INC
AVTX$AVTX Avalo Therapeutics, Inc.
GOSS$GOSS Gossamer Bio, Inc.
LXEO$LXEO Lexeo Therapeutics, Inc.
AMLX$AMLX Amylyx Pharmaceuticals, Inc.
SLNO$SLNO SOLENO THERAPEUTICS INC
OLMA$OLMA Olema Pharmaceuticals, Inc.
KALV$KALVCALL KalVista Pharmaceuticals, Inc.
MLYS$MLYS Mineralys Therapeutics, Inc.
RLAY$RLAY Relay Therapeutics, Inc.
QURE$QURE uniQure N.V.
TARS$TARS Tarsus Pharmaceuticals, Inc.
KYMR$KYMR Kymera Therapeutics, Inc.
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