Soleus Capital Management, L.P.
Sector Allocation
- Healthcare99.7%$2.9B
- Technology0.3%$9.2M
AUM History
13fpro.ai/research/fund/soleus-capital-management-l-p-1802630
Conviction and streaks
Diversifying · top 10 = 48.9%From the fund's last 12 quarters of 13F filings: positions held longest at size, and names it added to or trimmed several quarters running.
Largest positions — Q2 2026
KRYS
$349.1MCELC
$178.3MTGTX
$160.9MPODD
$159.7MNVCR
$150.2MUTHR
$122.2MINSP
$86.2MRIGL
$72.1MANIP
$71.8MBBNX
$68.8MVCEL
$64.9MPRAX
$59.4MGERN
$54.8MALKS
$53.9MERAS
$49.5MNPCE
$46.3MPGNY
$46.2MINDV
$43.7MPBLS
$40.1MFOCL
$37.9M
Top 20 stock positions. Options are left out: 13F reports them at the underlying's value.
13fpro.ai/research/fund/soleus-capital-management-l-p-1802630
Soleus Capital Management, L.P. 13F holdings — Q2 2026
$2.9B portfolio (+17.5% QoQ) · 97 holdings · Q2 2026 13F · top 10 are 49% of the stock portfolio
$349.1M
12.0% of stocks
-19%This quarter-4.1%Since filed10+ qtrsHeld$178.3M
6.1% of stocks
+33%This quarter-25.3%Since filed10+ qtrsHeld$160.9M
5.5% of stocks
-27%This quarter+9.8%Since filed10+ qtrsHeld$159.7M
5.5% of stocks
+86%This quarter+3.1%Since filed3 qtrsHeld$150.2M
5.2% of stocks
-6%This quarter-18.5%Since filed7 qtrsHeld$122.2M
4.2% of stocks
+21%This quarter+15.0%Since filed10+ qtrsHeldAIQualityAI quality score is Pro: unlock with a free trialEst. buyEstimated buy price is Pro: unlock with a free trialAdded 2 qtrs in a row$86.2M
3.0% of stocks
+235%This quarter+20.1%Since filed6 qtrsHeldAIQualityAI quality score is Pro: unlock with a free trialEst. buyEstimated buy price is Pro: unlock with a free trialAdded 2 qtrs in a row$72.1M
2.5% of stocks
NewThis quarter+18.8%Since filedNew this quarterHeld$71.8M
2.5% of stocks
+6%This quarter-2.6%Since filed8 qtrsHeldAIQualityAI quality score is Pro: unlock with a free trialEst. buyEstimated buy price is Pro: unlock with a free trialAdded 4 qtrs in a row$68.8M
2.4% of stocks
+0.9%This quarter+16.4%Since filed6 qtrsHeld
All holdings — Soleus Capital Management, L.P. (Q2 2026)
97 disclosed positions from the Form 13F-HR on SEC EDGAR, with quarter-over-quarter share changes. Largest by value first; the ten above are not repeated.
| # | Company | Held | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 11 | Vericel Corp | Healthcare | $64.9M | 2.2% | 1.46M | -43% | 5 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 12 | Praxis Precision Medicines, Inc. | Healthcare | $59.4M | 2.0% | 178K | -46% | 10+ qtrsTrimmed 5 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 13 | GERON CORP | Healthcare | $54.8M | 1.9% | 42.81M | +3% | 6 qtrsAdded 6 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 14 | Alkermes plc. | Healthcare | $53.9M | 1.9% | 1.03M | -48% | 3 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 15 | Erasca, Inc. | Healthcare | $49.5M | 1.7% | 2.70M | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 16 | NeuroPace Inc | Healthcare | $46.3M | 1.6% | 2.91M | -0.7% | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 17 | Progyny, Inc. | Healthcare | $46.2M | 1.6% | 1.60M | -22% | 2 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 18 | Indivior Pharmaceuticals, Inc. | Healthcare | $43.7M | 1.5% | 1.06M | -16% | 4 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 19 | Parabilis Medicines, Inc. | Healthcare | $40.1M | 1.4% | 1.47M | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 20 | EDAP TMS SAadr | Healthcare | $37.9M | 1.3% | 7.31M | — | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 21 | GLOBUS MEDICAL INC | Healthcare | $37.0M | 1.3% | 469K | -36% | 4 qtrsTrimmed 2 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 22 | Arcus Biosciences, Inc. | Healthcare | $36.0M | 1.2% | 1.17M | +159% | 3 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 23 | Syndax Pharmaceuticals Inc | Healthcare | $35.6M | 1.2% | 1.63M | -6% | 10+ qtrsTrimmed 2 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 24 | Nurix Therapeutics, Inc. | Healthcare | $35.5M | 1.2% | 1.47M | +56% | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 25 | Legend Biotech Corpadr | Healthcare | $34.8M | 1.2% | 1.21M | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 26 | $JBIO | Jade Biosciences, Inc. | Healthcare | $34.5M | 1.2% | 1.55M | +95% | |||
| 27 | $UNH | UNITEDHEALTH GROUP INC | Healthcare | $33.3M | 1.1% | 80K | New | |||
| 28 | $AVTX | Avalo Therapeutics, Inc. | Healthcare | $30.6M | 1.1% | 1.65M | +274% | |||
| 29 | $URGN | UroGen Pharma Ltd. | Healthcare | $30.5M | 1.1% | 830K | +14% | |||
| 30 | $MBX | MBX Biosciences, Inc. | Healthcare | $28.4M | 1.0% | 515K | +188% | |||
| 31 | $PALI | PALISADE BIO, INC. | Healthcare | $27.3M | 0.9% | 13.06M | New | |||
| 32 | $PHVS | Pharvaris N.V. | Healthcare | $25.3M | 0.9% | 731K | +4% | |||
| 33 | $ORGO | Organogenesis Holdings Inc. | Healthcare | $24.6M | 0.8% | 10.14M | +0.5% | |||
| 34 | $SUPN | SUPERNUS PHARMACEUTICALS, INC. | Healthcare | $24.2M | 0.8% | 520K | New | |||
| 35 | $PRCT | PROCEPT BioRobotics Corp | Healthcare | $22.6M | 0.8% | 1.00M | +527% | |||
| 36 | $TNGX | Tango Therapeutics, Inc. | Healthcare | $22.2M | 0.8% | 709K | +58% | |||
| 37 | $IKT | Inhibikase Therapeutics, Inc. | Healthcare | $22.1M | 0.8% | 10.88M | — | |||
| 38 | $TRVI | Trevi Therapeutics, Inc. | Healthcare | $22.0M | 0.8% | 1.18M | -27% | |||
| 39 | $BMRN | BIOMARIN PHARMACEUTICAL INC | Healthcare | $21.5M | 0.7% | 376K | -42% | |||
| 40 | $LIVN | LivaNova PLC | Healthcare | $21.0M | 0.7% | 255K | -56% | |||
| 41 | $ARGX | ARGENX SE | Healthcare | $18.5M | 0.6% | 20K | +470% | |||
| 42 | $NVCT | Nuvectis Pharma, Inc. | Healthcare | $18.4M | 0.6% | 1.00M | New | |||
| 43 | $CAPR | CAPRICOR THERAPEUTICS, INC. | Healthcare | $18.3M | 0.6% | 762K | New | |||
| 44 | $EWTX | Edgewise Therapeutics, Inc. | Healthcare | $18.3M | 0.6% | 451K | -69% | |||
| 45 | $PRLD | Prelude Therapeutics Inc | Healthcare | $18.0M | 0.6% | 3.38M | New | |||
| 46 | $XENE | Xenon Pharmaceuticals Inc. | Healthcare | $16.1M | 0.6% | 267K | -9% | |||
| 47 | $CCCC | C4 Therapeutics, Inc. | Healthcare | $15.8M | 0.5% | 3.38M | -11% | |||
| 48 | $KNSA | Kiniksa Pharmaceuticals International, plc | Healthcare | $15.8M | 0.5% | 246K | -53% | |||
| 49 | $KIDS | ORTHOPEDIATRICS CORP | Healthcare | $14.0M | 0.5% | 732K | +19% | |||
| 50 | $AVLN | Avalyn Pharma Inc. | Healthcare | $13.8M | 0.5% | 419K | New | |||
| 51 | $BDSX | BIODESIX INC | Healthcare | $13.2M | 0.5% | 586K | +41% | |||
| 52 | $SYRE | Spyre Therapeutics, Inc. | Healthcare | $13.1M | 0.5% | 147K | New | |||
| 53 | $TWST | Twist Bioscience Corp | Healthcare | $10.8M | 0.4% | 105K | -91% | |||
| 54 | $VIR | Vir Biotechnology, Inc. | Healthcare | $10.2M | 0.3% | 1.00M | -50% | |||
| 55 | $ALNY | ALNYLAM PHARMACEUTICALS, INC. | Healthcare | $9.9M | 0.3% | 33K | -75% | |||
| 56 | $IMVT | Immunovant, Inc. | Healthcare | $9.7M | 0.3% | 252K | +10% | |||
| 57 | $INSM | INSMED Inc | Healthcare | $9.6M | 0.3% | 90K | +780% | |||
| 58 | $SEPN | Septerna, Inc. | Healthcare | $9.2M | 0.3% | 275K | — | |||
| 59 | $SOPH | SOPHiA GENETICS SA | Technology | $9.0M | 0.3% | 1.56M | -15% | |||
| 60 | $NKTR | NEKTAR THERAPEUTICS | Healthcare | $9.0M | 0.3% | 128K | New | |||
| 61 | $MIRM | Mirum Pharmaceuticals, Inc. | Healthcare | $8.8M | 0.3% | 75K | -81% | |||
| 62 | $AORT | ARTIVION, INC. | Healthcare | $8.7M | 0.3% | 388K | New | |||
| 63 | $TNDM | TANDEM DIABETES CARE INC | Healthcare | $8.7M | 0.3% | 575K | -27% | |||
| 64 | $ELVN | Enliven Therapeutics, Inc. | Healthcare | $8.4M | 0.3% | 166K | -28% | |||
| 65 | $SION | Sionna Therapeutics, Inc. | Healthcare | $7.8M | 0.3% | 178K | -39% | |||
| 66 | $BLTE | BELITE BIO, INC | Healthcare | $7.8M | 0.3% | 51K | New | |||
| 67 | $CERS | CERUS CORP | Healthcare | $7.3M | 0.3% | 2.50M | -77% | |||
| 68 | $SLN | Silence Therapeutics plc | Healthcare | $6.9M | 0.2% | 630K | New | |||
| 69 | $IMUX | IMMUNIC, INC. | Healthcare | $6.9M | 0.2% | 450K | -90% | |||
| 70 | $IVVD | Invivyd, Inc. | Healthcare | $6.7M | 0.2% | 7.71M | — | |||
| 71 | $MRK | Merck & Co., Inc. | Healthcare | $6.4M | 0.2% | 50K | -75% | |||
| 72 | $RLMD | RELMADA THERAPEUTICS, INC. | Healthcare | $5.8M | 0.2% | 842K | — | |||
| 73 | $GPCR | Structure Therapeutics Inc. | Healthcare | $5.7M | 0.2% | 107K | +34% | |||
| 74 | $EOLS | Evolus, Inc. | Healthcare | $5.7M | 0.2% | 822K | -63% | |||
| 75 | $ANL | Adlai Nortye Group Ltd. | Healthcare | $4.7M | 0.2% | 406K | New | |||
| 76 | $ZNTL | Zentalis Pharmaceuticals, Inc. | Healthcare | $4.6M | 0.2% | 950K | New | |||
| 77 | $KPTI | Karyopharm Therapeutics Inc. | Healthcare | $4.3M | 0.1% | 440K | — | |||
| 78 | $CNTX | Context Therapeutics Inc. | Healthcare | $3.9M | 0.1% | 7.06M | +1% | |||
| 79 | $LUNG | Pulmonx Corp | Healthcare | $3.6M | 0.1% | 2.79M | — | |||
| 80 | $SABS | SAB Biotherapeutics, Inc. | Healthcare | $3.5M | 0.1% | 900K | -14% | |||
| 81 | $TECX | Tectonic Therapeutic, Inc. | Healthcare | $3.5M | 0.1% | 102K | -16% | |||
| 82 | $AXGN | Axogen, Inc. | Healthcare | $2.6M | 0.1% | 57K | -92% | |||
| 83 | $MSLE | Satellos Bioscience Inc. | Healthcare | $2.4M | 0.1% | 314K | -24% | |||
| 84 | $AVBP | ArriVent BioPharma, Inc. | Healthcare | $1.7M | 0.1% | 50K | New | |||
| 85 | $CORT | CORCEPT THERAPEUTICS INC | Healthcare | $1.7M | 0.1% | 20K | -93% | |||
| 86 | $SLDB | Solid Biosciences Inc. | Healthcare | $1.5M | 0.1% | 150K | New | |||
| 87 | $VCYT | VERACYTE, INC. | Healthcare | $1.5M | 0.1% | 25K | -92% | |||
| 88 | $CGEM | Cullinan Therapeutics, Inc. | Healthcare | $911K | 0.0% | 50K | -88% | |||
| 89 | $NSPR | InspireMD, Inc. | Healthcare | $732K | 0.0% | 1.05M | — | |||
| 90 | $WGS | GeneDx Holdings Corp. | Healthcare | $687K | 0.0% | 10K | New | |||
| 91 | $IOVA | IOVANCE BIOTHERAPEUTICS, INC. | Healthcare | $624K | 0.0% | 150K | -85% | |||
| 92 | $LRMR | Larimar Therapeutics, Inc. | Healthcare | $574K | 0.0% | 188K | -82% | |||
| 93 | $CGON | CG Oncology, Inc. | Healthcare | $355K | 0.0% | 5,000 | -75% | |||
| 94 | $QNRX | Quoin Pharmaceuticals Ltd. | Healthcare | $352K | 0.0% | 73K | — | |||
| 95 | $EQ | Equillium, Inc. | Healthcare | $288K | 0.0% | 90K | New | |||
| 96 | $NTRA | Natera, Inc. | Healthcare | $271K | 0.0% | 1,000 | -99% | |||
| 97 | $NEO | NEOGENOMICS INC | Technology | $146K | 0.0% | 10K | -94% |
What changed in Q2 2026
Against the previous quarter's 13F: 21 new, 25 added to, 42 trimmed, 17 sold out. Share-count changes; largest moves by dollar size first.
New positions (21)
$ERASErasca, Inc.$49.5M
first bought this quarter
$PBLSParabilis Medicines, Inc.$40.1M
first bought this quarter
$LEGNLegend Biotech Corp$34.8M
first bought this quarter
$UNHUNITEDHEALTH GROUP INC$33.3M
first bought this quarter
$PALIPALISADE BIO, INC.$27.3M
first bought this quarter
$SUPNSUPERNUS PHARMACEUTICALS, INC.$24.2M
first bought this quarter
+15 more in the Excel export
Added to (25)
$PODDINSULET CORP+86%
now $159.7M · held 3 qtrs, 3 adds in a row
$INSPInspire Medical Systems, Inc.+235%
now $86.2M · held 6 qtrs, 2 adds in a row
$CELCCelcuity Inc.+33%
now $178.3M · held 10+ qtrs
$AVTXAvalo Therapeutics, Inc.+274%
now $30.6M · held 3 qtrs
$RCUSArcus Biosciences, Inc.+159%
now $36.0M · held 3 qtrs
$UTHRUNITED THERAPEUTICS Corp+21%
now $122.2M · held 10+ qtrs, 2 adds in a row
+19 more in the Excel export
Trimmed (42)
$TWSTTwist Bioscience Corp-91%
now $10.8M · held 5 qtrs, 2 trims in a row
$KRYSKrystal Biotech, Inc.-19%
now $349.1M · held 10+ qtrs
$IMUXIMMUNIC, INC.-90%
now $6.9M · held 2 qtrs
$TGTXTG THERAPEUTICS, INC.-27%
now $160.9M · held 10+ qtrs
$PRAXPraxis Precision Medicines, Inc.-46%
now $59.4M · held 10+ qtrs, 5 trims in a row
$ALKSAlkermes plc.-48%
now $53.9M · held 3 qtrs
+36 more in the Excel export
Holdings by quarter
Every 13F Soleus Capital Management, L.P. has filed, 26 earlier quarters. Pick one to see what it held then.
Is it too late to follow Soleus Capital Management, L.P.?
Q2 2026 13F filed with the SEC on Aug 11, 2026. Prices are closing prices as of Oct 26, 2026.
Average quality of Soleus Capital Management, L.P.'s top 20 holdings: 66/100 (our AI quality score, weighted by position size; 13 of the 20 are scored)
Top 10 since filing
-0.5%
Value-weighted move of the 10 largest stock positions
Turnover
29%
Last quarter; 129% over the last 4
Top 10 weight
49%
Share of the stock portfolio in its 10 largest positions
Held 4+ quarters
70%
Share of portfolio value in positions held a year or more
Highest-quality names it owns(among its 100 largest positions)
The 8 highest-scoring companies in this portfolio are a Pro feature.
How these are measured
- Moves since the quarter-end and since the filing date use our own daily closing prices, from the close on (or just before) each date to the latest close.
- Turnover is the lesser of shares bought or sold in a quarter, valued at the quarter-end prices in the 13F, divided by the average of the two quarters' stock portfolio values.
- Quarters held and add/trim streaks count back only through quarters whose filed holdings add up to the filing's own cover-page total (back to Q1 2024 for this fund). A change counts as an add or a trim when the split-adjusted share count moves by more than 1%.
- Estimate, not the fund's reported cost. For each quarter in the current holding period in which the fund's share count rose (split-adjusted), we take that quarter's average daily close and weight it by the shares added; sales do not change an average cost. Quarters where the stock's price history and the 13F's own implied price disagree by more than 2x are left out.
- Put and call option rows report the value of the underlying shares, not a position the fund paid for, so they are left out of all of the above.
Portfolio Overview
Soleus Capital Management, L.P. disclosed 97 positions worth $2.9B in its Form 13F-HR for Q2 2026, led by $KRYS (Krystal Biotech, Inc.) at 12.0% of the equity portfolio, followed by $CELC and $TGTX. During the quarter the fund opened 21 new positions and exited 17 — including a new stake in $ERAS and a full exit from $PCVX. The portfolio is most concentrated in Healthcare (99.7% of disclosed assets). All figures are sourced directly from Soleus Capital Management, L.P.’s Form 13F-HR filing with the SEC under CIK 1802630.
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AI-Powered Hedge Fund Analysis: Soleus Capital Management, L.P.
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