Soleus Capital Management, L.P.

Institutional InvestorSimilar funds →SEC EDGAR: CIK 1802630
Institutional-grade research for retail investors

13F Reported Value

$2.5B

Holdings

93

Latest Filing

2026-03-31

Filing Quarter

Q1 2026

Portfolio Overview

Soleus Capital Management, L.P. disclosed 93 positions worth $2.5B in its Form 13F-HR for Q1 2026, led by $KRYS (Krystal Biotech, Inc.) at 12.1% of the equity portfolio, followed by $CELC and $TGTX. During the quarter the fund opened 24 new positions and exited 26 — including a new stake in $PGNY. The portfolio is most concentrated in Healthcare (99.6% of disclosed assets). All figures are sourced directly from Soleus Capital Management, L.P.’s Form 13F-HR filing with the SEC under CIK 1802630.

Sector Allocation

HealthcareTechnology

AUM History

Top Equity Holdings by Value

Quarterly Activity — Q1 2026

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Top Holdings

AI Quality Scored

Unlock AI quality scores for every holding

32-signal composite ranking on each of Soleus Capital Management, L.P.'s 93 positions.

Showing top 10 of 93 holdings.

Sector Allocation

Healthcare

$2.5B

Technology

$10.5M

Full Holdings — Soleus Capital Management, L.P. (Q1 2026)

All 93 disclosed positions from the latest Form 13F-HR, with quarter-over-quarter share changes and 13F Pro quality scores. Sourced from SEC EDGAR.

#TickerCompanyValueWeightQoQQuality
1KRYS$KRYSKrystal Biotech, Inc.$297.9M12.1%+23%75.9
2CELC$CELCCelcuity Inc.$146.6M5.9%-29%
3TGTX$TGTXTG THERAPEUTICS, INC.$133.9M5.4%+28%68.4
4PODD$PODDINSULET CORP$118.0M4.8%+275%70.4
5NVCR$NVCRNovoCure Ltd$114.4M4.6%+23%
6UTHR$UTHRUNITED THERAPEUTICS Corp$111.0M4.5%+212%80.1
7PRAX$PRAXPraxis Precision Medicines, Inc.$106.5M4.3%-9%
8VCEL$VCELVericel Corp$82.0M3.3%+234%46
9ALKS$ALKSAlkermes plc.$69.7M2.8%+49%
10ANIP$ANIPANI PHARMACEUTICALS INC$63.1M2.5%+69%68.6
11GMED$GMEDGLOBUS MEDICAL INC$62.9M2.5%-18%77.6
12GERN$GERNGERON CORP$61.8M2.5%+78%
13TWST$TWSTTwist Bioscience Corp$58.3M2.4%-34%33.3
14EWTX$EWTXEdgewise Therapeutics, Inc.$45.7M1.9%+59%
15BBNX$BBNXBeta Bionics, Inc.$43.6M1.8%+72%22.8
16ALNY$ALNYALNYLAM PHARMACEUTICALS, INC.$43.6M1.8%+88%60.9
17SNDX$SNDXSyndax Pharmaceuticals Inc$40.3M1.6%-23%30
18INDV$INDVIndivior Pharmaceuticals, Inc.$38.8M1.6%+1174%64.6
19NPCE$NPCENeuroPace Inc$38.6M1.6%+8%30.5
20LIVN$LIVNLivaNova PLC$37.0M1.5%+3%
21MIRM$MIRMMirum Pharmaceuticals, Inc.$37.0M1.5%-30%32.7
22BMRN$BMRNBIOMARIN PHARMACEUTICAL INC$36.8M1.5%-51%74.1
23PGNY$PGNYProgyny, Inc.$35.1M1.4%NEW59
24INSP$INSPInspire Medical Systems, Inc.$29.7M1.2%+92%46
25FOCL$FOCLEDAP TMS SA$27.2M1.1%+0%
26KNSA$KNSAKiniksa Pharmaceuticals International, plc$25.1M1.0%-11%
27MRK$MRKMerck & Co., Inc.$24.4M1.0%NEW70.9
28ORGO$ORGOOrganogenesis Holdings Inc.$23.9M1.0%+1%20.5
29NTRA$NTRANatera, Inc.$23.8M1.0%+495%46.4
30AXGN$AXGNAxogen, Inc.$22.5M0.9%-44%38
31PCVX$PCVXVaxcyte, Inc.$22.4M0.9%-37%
32ICLR$ICLRICON PLC$21.2M0.9%NEW
33PHVS$PHVSPharvaris N.V.$19.8M0.8%+0%
34CERS$CERSCERUS CORP$19.6M0.8%+169%29.3
35TRVI$TRVITrevi Therapeutics, Inc.$19.3M0.8%+80%
36IKT$IKTInhibikase Therapeutics, Inc.$18.3M0.7%+0%
37CNTX$CNTXContext Therapeutics Inc.$18.2M0.7%NEW
38VIR$VIRVir Biotechnology, Inc.$17.9M0.7%NEW5.6
39XENE$XENEXenon Pharmaceuticals Inc.$17.0M0.7%NEW12.9
40TVTX$TVTXTravere Therapeutics, Inc.$16.2M0.7%NEW39.2
41TNDM$TNDMTANDEM DIABETES CARE INC$15.0M0.6%NEW34.8
42NRIX$NRIXNurix Therapeutics, Inc.$14.5M0.6%-23%13.2
43URGN$URGNUroGen Pharma Ltd.$13.1M0.5%+385%
44SION$SIONSionna Therapeutics, Inc.$11.8M0.5%+9%
45CORT$CORTCORCEPT THERAPEUTICS INC$11.5M0.5%NEW55.4
46JBIO$JBIOJade Biosciences, Inc.$11.2M0.5%+0%
47VCYT$VCYTVERACYTE, INC.$10.3M0.4%+3099%59.5
48IVVD$IVVDInvivyd, Inc.$10.0M0.4%+0%25.7
49CCCC$CCCCC4 Therapeutics, Inc.$10.0M0.4%+0%6.5
50KIDS$KIDSORTHOPEDIATRICS CORP$9.8M0.4%+17%33.4
51RCUS$RCUSArcus Biosciences, Inc.$9.8M0.4%-37%12
52TNGX$TNGXTango Therapeutics, Inc.$9.4M0.4%+4400%26.9
53EOLS$EOLSEvolus, Inc.$9.2M0.4%+110%30
54SOPH$SOPHSOPHiA GENETICS SA$9.2M0.4%NEW
55ELVN$ELVNEnliven Therapeutics, Inc.$9.1M0.4%-77%
56INBX$INBXInhibrx Biosciences, Inc.$8.8M0.4%+424%3.1
57DXCM$DXCMDEXCOM INC$8.8M0.4%-89%77.9
58SEPN$SEPNSepterna, Inc.$6.6M0.3%-28%44.6
59AVTX$AVTXAvalo Therapeutics, Inc.$6.6M0.3%+0%4.6
60BDSX$BDSXBIODESIX INC$6.0M0.2%NEW32.3
61RLMD$RLMDRELMADA THERAPEUTICS, INC.$5.9M0.2%NEW
62CGEM$CGEMCullinan Therapeutics, Inc.$5.8M0.2%NEW
63IMVT$IMVTImmunovant, Inc.$5.7M0.2%-79%
64MBX$MBXMBX Biosciences, Inc.$5.3M0.2%-56%
65IMUX$IMUXIMMUNIC, INC.$5.0M0.2%NEW
66LRMR$LRMRLarimar Therapeutics, Inc.$4.8M0.2%NEW
67ETON$ETONEton Pharmaceuticals, Inc.$4.1M0.2%NEW51.9
68SABS$SABSSAB Biotherapeutics, Inc.$4.0M0.2%NEW
69PRCT$PRCTPROCEPT BioRobotics Corp$4.0M0.2%NEW34.8
70GPCR$GPCRStructure Therapeutics Inc.$3.9M0.2%-11%
71TECX$TECXTectonic Therapeutic, Inc.$3.8M0.1%NEW
72LUNG$LUNGPulmonx Corp$3.6M0.1%+37%23.9
73IOVA$IOVAIOVANCE BIOTHERAPEUTICS, INC.$3.5M0.1%NEW30.6
74ARGX$ARGXARGENX SE$2.6M0.1%-89%
75KPTI$KPTIKaryopharm Therapeutics Inc.$2.5M0.1%+0%20.4
76MSLE$MSLESatellos Bioscience Inc.$2.3M0.1%NEW
77ARWR$ARWRARROWHEAD PHARMACEUTICALS, INC.$1.8M0.1%NEW74.4
78NSPR$NSPRInspireMD, Inc.$1.7M0.1%-9%
79INSM$INSMINSMED Inc$1.7M0.1%-79%29.4
80CTMX$CTMXCytomX Therapeutics, Inc.$1.4M0.1%NEW19.1
81CGON$CGONCG Oncology, Inc.$1.4M0.1%-88%28
82NEO$NEONEOGENOMICS INC$1.3M0.1%-59%34.6
83QNRX$QNRXQuoin Pharmaceuticals, Ltd.$480,0180.0%+191%
84COGT$COGTCogent Biosciences, Inc.$384,9000.0%-92%
85TYRA$TYRATyra Biosciences, Inc.$383,0000.0%-92%
86STAA$STAASTAAR SURGICAL CO$374,0000.0%-20%18
87ANAB$ANABANAPTYSBIO, INC$332,7600.0%-96%29.4
88RAPP$RAPPRapport Therapeutics, Inc.$312,9000.0%NEW
89RIGL$RIGLRIGEL PHARMACEUTICALS INC$270,4000.0%-97%73.9
90ZYME$ZYMEZymeworks Inc.$250,4000.0%-90%27.2
91LBRX$LBRXLB PHARMACEUTICALS INC$246,6000.0%+0%
92ORKA$ORKAOruka Therapeutics, Inc.$245,2500.0%-97%
93JSPR$JSPRJasper Therapeutics, Inc.$242,1050.0%+38%

New Positions (24)

PGNY$PGNY Progyny, Inc.$35.1M
MRK$MRK Merck & Co., Inc.$24.4M
ICLR$ICLR ICON PLC$21.2M
CNTX$CNTX Context Therapeutics Inc.$18.2M
VIR$VIR Vir Biotechnology, Inc.$17.9M
XENE$XENE Xenon Pharmaceuticals Inc.$17.0M
TVTX$TVTX Travere Therapeutics, Inc.$16.2M
TNDM$TNDM TANDEM DIABETES CARE INC$15.0M
CORT$CORT CORCEPT THERAPEUTICS INC$11.5M
SOPH$SOPH SOPHiA GENETICS SA$9.2M
BDSX$BDSX BIODESIX INC$6.0M
RLMD$RLMD RELMADA THERAPEUTICS, INC.$5.9M
CGEM$CGEM Cullinan Therapeutics, Inc.$5.8M
IMUX$IMUX IMMUNIC, INC.$5.0M
LRMR$LRMR Larimar Therapeutics, Inc.$4.8M

Exited Positions (26)

PUT SPDR SERIES TRUST
FOLD$FOLD AMICUS THERAPEUTICS, INC.
GSK$GSK GSK plc
RAPT$RAPT RAPT Therapeutics, Inc.
NBIX$NBIX NEUROCRINE BIOSCIENCES INC
TFX$TFX TELEFLEX INC
CAPR$CAPR CAPRICOR THERAPEUTICS, INC.
THC$THC TENET HEALTHCARE CORP
TERN$TERN Terns Pharmaceuticals, Inc.
CIDARA THERAPEUTICS INC
ERAS$ERAS Erasca, Inc.
BLTE$BLTE BELITE BIO, INC
ABVX$ABVX Abivax S.A.
MLTX$MLTX MoonLake Immunotherapeutics
CALC$CALC CalciMedica, Inc.

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