Soleus Capital Management, L.P.
13F Reported Value
ⓘ$2.5B
Holdings
93
Latest Filing
2026-03-31
Filing Quarter
Q1 2026
Portfolio Overview
Soleus Capital Management, L.P. disclosed 93 positions worth $2.5B in its Form 13F-HR for Q1 2026, led by $KRYS (Krystal Biotech, Inc.) at 12.1% of the equity portfolio, followed by $CELC and $TGTX. During the quarter the fund opened 24 new positions and exited 26 — including a new stake in $PGNY. The portfolio is most concentrated in Healthcare (99.6% of disclosed assets). All figures are sourced directly from Soleus Capital Management, L.P.’s Form 13F-HR filing with the SEC under CIK 1802630.
AI Fund Analysis
ConcentratingSector Allocation
AUM History
Top Equity Holdings by Value
Quarterly Activity — Q1 2026
Click any card to unlockTop Holdings
- 75.9#116
Quality
$297.9M1,153,087 sh - —
Quality
$146.6M1,284,378 sh - 68.4#417
Quality
$133.9M4,029,319 sh - 70.4
Quality
$118.0M562,500 sh - —
Quality
$114.4M10,492,391 sh - 80.1
Quality
$111.0M187,187 sh - $106.5M330,517 sh
- 46.0
Quality
$82.0M2,549,079 sh - —
Quality
$69.7M1,970,864 sh - 68.6
Quality
$63.1M820,243 sh
| Company | Quality | Value | Shares |
|---|---|---|---|
| 75.9#116 | $297.9M | 1,153,087 | |
| — | $146.6M | 1,284,378 | |
| 68.4#417 | $133.9M | 4,029,319 | |
| 70.4 | $118.0M | 562,500 | |
| — | $114.4M | 10,492,391 | |
| 80.1 | $111.0M | 187,187 | |
| — | $106.5M | 330,517 | |
| 46.0 | $82.0M | 2,549,079 | |
| — | $69.7M | 1,970,864 | |
| 68.6 | $63.1M | 820,243 |
Unlock AI quality scores for every holding
32-signal composite ranking on each of Soleus Capital Management, L.P.'s 93 positions.
Showing top 10 of 93 holdings.
Sector Allocation
Healthcare
$2.5B
Technology
$10.5M
Full Holdings — Soleus Capital Management, L.P. (Q1 2026)
All 93 disclosed positions from the latest Form 13F-HR, with quarter-over-quarter share changes and 13F Pro quality scores. Sourced from SEC EDGAR.
| # | Ticker | Company | Value | Weight | QoQ | Quality |
|---|---|---|---|---|---|---|
| 1 | Krystal Biotech, Inc. | $297.9M | 12.1% | +23% | 75.9 | |
| 2 | Celcuity Inc. | $146.6M | 5.9% | -29% | — | |
| 3 | TG THERAPEUTICS, INC. | $133.9M | 5.4% | +28% | 68.4 | |
| 4 | INSULET CORP | $118.0M | 4.8% | +275% | 70.4 | |
| 5 | NovoCure Ltd | $114.4M | 4.6% | +23% | — | |
| 6 | UNITED THERAPEUTICS Corp | $111.0M | 4.5% | +212% | 80.1 | |
| 7 | Praxis Precision Medicines, Inc. | $106.5M | 4.3% | -9% | — | |
| 8 | Vericel Corp | $82.0M | 3.3% | +234% | 46 | |
| 9 | Alkermes plc. | $69.7M | 2.8% | +49% | — | |
| 10 | ANI PHARMACEUTICALS INC | $63.1M | 2.5% | +69% | 68.6 | |
| 11 | GLOBUS MEDICAL INC | $62.9M | 2.5% | -18% | 77.6 | |
| 12 | GERON CORP | $61.8M | 2.5% | +78% | — | |
| 13 | Twist Bioscience Corp | $58.3M | 2.4% | -34% | 33.3 | |
| 14 | Edgewise Therapeutics, Inc. | $45.7M | 1.9% | +59% | — | |
| 15 | Beta Bionics, Inc. | $43.6M | 1.8% | +72% | 22.8 | |
| 16 | ALNYLAM PHARMACEUTICALS, INC. | $43.6M | 1.8% | +88% | 60.9 | |
| 17 | Syndax Pharmaceuticals Inc | $40.3M | 1.6% | -23% | 30 | |
| 18 | Indivior Pharmaceuticals, Inc. | $38.8M | 1.6% | +1174% | 64.6 | |
| 19 | NeuroPace Inc | $38.6M | 1.6% | +8% | 30.5 | |
| 20 | LivaNova PLC | $37.0M | 1.5% | +3% | — | |
| 21 | Mirum Pharmaceuticals, Inc. | $37.0M | 1.5% | -30% | 32.7 | |
| 22 | BIOMARIN PHARMACEUTICAL INC | $36.8M | 1.5% | -51% | 74.1 | |
| 23 | Progyny, Inc. | $35.1M | 1.4% | NEW | 59 | |
| 24 | Inspire Medical Systems, Inc. | $29.7M | 1.2% | +92% | 46 | |
| 25 | EDAP TMS SA | $27.2M | 1.1% | +0% | — | |
| 26 | Kiniksa Pharmaceuticals International, plc | $25.1M | 1.0% | -11% | — | |
| 27 | Merck & Co., Inc. | $24.4M | 1.0% | NEW | 70.9 | |
| 28 | Organogenesis Holdings Inc. | $23.9M | 1.0% | +1% | 20.5 | |
| 29 | Natera, Inc. | $23.8M | 1.0% | +495% | 46.4 | |
| 30 | Axogen, Inc. | $22.5M | 0.9% | -44% | 38 | |
| 31 | Vaxcyte, Inc. | $22.4M | 0.9% | -37% | — | |
| 32 | ICON PLC | $21.2M | 0.9% | NEW | — | |
| 33 | Pharvaris N.V. | $19.8M | 0.8% | +0% | — | |
| 34 | CERUS CORP | $19.6M | 0.8% | +169% | 29.3 | |
| 35 | Trevi Therapeutics, Inc. | $19.3M | 0.8% | +80% | — | |
| 36 | Inhibikase Therapeutics, Inc. | $18.3M | 0.7% | +0% | — | |
| 37 | Context Therapeutics Inc. | $18.2M | 0.7% | NEW | — | |
| 38 | Vir Biotechnology, Inc. | $17.9M | 0.7% | NEW | 5.6 | |
| 39 | Xenon Pharmaceuticals Inc. | $17.0M | 0.7% | NEW | 12.9 | |
| 40 | Travere Therapeutics, Inc. | $16.2M | 0.7% | NEW | 39.2 | |
| 41 | TANDEM DIABETES CARE INC | $15.0M | 0.6% | NEW | 34.8 | |
| 42 | Nurix Therapeutics, Inc. | $14.5M | 0.6% | -23% | 13.2 | |
| 43 | UroGen Pharma Ltd. | $13.1M | 0.5% | +385% | — | |
| 44 | Sionna Therapeutics, Inc. | $11.8M | 0.5% | +9% | — | |
| 45 | CORCEPT THERAPEUTICS INC | $11.5M | 0.5% | NEW | 55.4 | |
| 46 | Jade Biosciences, Inc. | $11.2M | 0.5% | +0% | — | |
| 47 | VERACYTE, INC. | $10.3M | 0.4% | +3099% | 59.5 | |
| 48 | Invivyd, Inc. | $10.0M | 0.4% | +0% | 25.7 | |
| 49 | C4 Therapeutics, Inc. | $10.0M | 0.4% | +0% | 6.5 | |
| 50 | ORTHOPEDIATRICS CORP | $9.8M | 0.4% | +17% | 33.4 | |
| 51 | Arcus Biosciences, Inc. | $9.8M | 0.4% | -37% | 12 | |
| 52 | Tango Therapeutics, Inc. | $9.4M | 0.4% | +4400% | 26.9 | |
| 53 | Evolus, Inc. | $9.2M | 0.4% | +110% | 30 | |
| 54 | SOPHiA GENETICS SA | $9.2M | 0.4% | NEW | — | |
| 55 | Enliven Therapeutics, Inc. | $9.1M | 0.4% | -77% | — | |
| 56 | Inhibrx Biosciences, Inc. | $8.8M | 0.4% | +424% | 3.1 | |
| 57 | DEXCOM INC | $8.8M | 0.4% | -89% | 77.9 | |
| 58 | Septerna, Inc. | $6.6M | 0.3% | -28% | 44.6 | |
| 59 | Avalo Therapeutics, Inc. | $6.6M | 0.3% | +0% | 4.6 | |
| 60 | BIODESIX INC | $6.0M | 0.2% | NEW | 32.3 | |
| 61 | RELMADA THERAPEUTICS, INC. | $5.9M | 0.2% | NEW | — | |
| 62 | Cullinan Therapeutics, Inc. | $5.8M | 0.2% | NEW | — | |
| 63 | Immunovant, Inc. | $5.7M | 0.2% | -79% | — | |
| 64 | MBX Biosciences, Inc. | $5.3M | 0.2% | -56% | — | |
| 65 | IMMUNIC, INC. | $5.0M | 0.2% | NEW | — | |
| 66 | Larimar Therapeutics, Inc. | $4.8M | 0.2% | NEW | — | |
| 67 | Eton Pharmaceuticals, Inc. | $4.1M | 0.2% | NEW | 51.9 | |
| 68 | SAB Biotherapeutics, Inc. | $4.0M | 0.2% | NEW | — | |
| 69 | PROCEPT BioRobotics Corp | $4.0M | 0.2% | NEW | 34.8 | |
| 70 | Structure Therapeutics Inc. | $3.9M | 0.2% | -11% | — | |
| 71 | Tectonic Therapeutic, Inc. | $3.8M | 0.1% | NEW | — | |
| 72 | Pulmonx Corp | $3.6M | 0.1% | +37% | 23.9 | |
| 73 | IOVANCE BIOTHERAPEUTICS, INC. | $3.5M | 0.1% | NEW | 30.6 | |
| 74 | ARGENX SE | $2.6M | 0.1% | -89% | — | |
| 75 | Karyopharm Therapeutics Inc. | $2.5M | 0.1% | +0% | 20.4 | |
| 76 | Satellos Bioscience Inc. | $2.3M | 0.1% | NEW | — | |
| 77 | ARROWHEAD PHARMACEUTICALS, INC. | $1.8M | 0.1% | NEW | 74.4 | |
| 78 | InspireMD, Inc. | $1.7M | 0.1% | -9% | — | |
| 79 | INSMED Inc | $1.7M | 0.1% | -79% | 29.4 | |
| 80 | CytomX Therapeutics, Inc. | $1.4M | 0.1% | NEW | 19.1 | |
| 81 | CG Oncology, Inc. | $1.4M | 0.1% | -88% | 28 | |
| 82 | NEOGENOMICS INC | $1.3M | 0.1% | -59% | 34.6 | |
| 83 | Quoin Pharmaceuticals, Ltd. | $480,018 | 0.0% | +191% | — | |
| 84 | Cogent Biosciences, Inc. | $384,900 | 0.0% | -92% | — | |
| 85 | Tyra Biosciences, Inc. | $383,000 | 0.0% | -92% | — | |
| 86 | STAAR SURGICAL CO | $374,000 | 0.0% | -20% | 18 | |
| 87 | ANAPTYSBIO, INC | $332,760 | 0.0% | -96% | 29.4 | |
| 88 | Rapport Therapeutics, Inc. | $312,900 | 0.0% | NEW | — | |
| 89 | RIGEL PHARMACEUTICALS INC | $270,400 | 0.0% | -97% | 73.9 | |
| 90 | Zymeworks Inc. | $250,400 | 0.0% | -90% | 27.2 | |
| 91 | LB PHARMACEUTICALS INC | $246,600 | 0.0% | +0% | — | |
| 92 | Oruka Therapeutics, Inc. | $245,250 | 0.0% | -97% | — | |
| 93 | Jasper Therapeutics, Inc. | $242,105 | 0.0% | +38% | — |
New Positions (24)
Exited Positions (26)
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