13F Pro quality score
Rank #950 of 2,925TOP 50%
Rankings refresh quarterly once 80% of peers have filed. Next update: ~Nov 14, 2026.
Reported revenue, net income and operating margin by fiscal year, from Septerna, Inc.'s annual filings on SEC EDGAR.
| Period | Form | Revenue | Net income | Op. marginOperating margin |
|---|---|---|---|---|
| FY 2025 | 10-K | $46.0M | $-48.9M | -148.6% |
| FY 2024 | 10-K | $1.1M | $-71.8M | — |
| FY 2023 | 10-K | $151.0K | $4.2M | — |
Ranked by quality-factor profile and overlapping institutional ownership, from the latest 13F filings and SEC financials.
Officers, directors and 10% owners with a Form 4 filed in the last 24 months, most recent first. From SEC EDGAR.
Septerna, Inc. (SEPN) stock profile, AI quality score, and SEC EDGAR financial data, a Healthcare sector company. 13F Pro's AI-powered ranking engine scores SEPN at 59.2/100 on a composite quality score built from its SEC filings, placing it at rank #950 of 2,925 stocks — the top half of the AI-ranked universe. SEPN scores in the top quartile across revenue growth (99.4), free cash flow (99.0), earnings quality (94.7). Areas of concern include revenue scale (16.0) and profitability (16.3), which score below median versus the broader universe. Shareholder dilution risk is elevated at 9.4/100, reflecting ongoing share issuance or stock-based compensation. Based on the latest XBRL financial filings (Q2 2026), Septerna, Inc. reports quarterly revenue of $26.7M, net income of $-13.0M, an operating margin of -62.9%. Top institutional holders of SEPN by reported 13-F value include RA CAPITAL MANAGEMENT, L.P., TRV GP V, DRIEHAUS CAPITAL MANAGEMENT, based on the most recent SEC filings. SEPN trades on the Nasdaq exchange and files with the SEC under CIK 1984086. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate SEPN daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for Septerna, Inc. directly from SEC EDGAR.
Financials through the period ended SEC EDGAR: CIK 1984086 →