Caligan Partners LP
Sector Allocation
- Healthcare99.2%$2.1B
- Other0.8%$15.7M
AUM History
13fpro.ai/research/fund/caligan-partners-lp-1727492
Conviction and streaks
Concentrating · top 10 = 82.9%From the fund's last 12 quarters of 13F filings: positions held longest at size, and names it added to or trimmed several quarters running.
Largest positions — Q2 2026
LQDA
$647.3MRVMD
$367.4MABVX
$207.6MPCVX
$127.2MEXEL
$84.5MTNGX
$78.2MAVTX
$58.5MXENE
$53.7MADMA
$47.9MLBRX
$46.7MIMCR
$43.9MVRDN
$40.3MVOR
$35.4MSABS
$31.1MIVA
$30.9MAURA
$30.5MTYRA
$25.8MIRD
$25.0MANIK
$21.0MSGMT
$19.3M
Top 20 stock positions. Options are left out: 13F reports them at the underlying's value.
13fpro.ai/research/fund/caligan-partners-lp-1727492
Caligan Partners LP 13F holdings — Q2 2026
$2.1B portfolio (+41.5% QoQ) · 28 holdings · Q2 2026 13F · top 10 are 83% of the stock portfolio
Includes $53.0M of put/call options ($0 puts, $53.0M calls), which 13F rules report at the value of the underlying shares, not the premium at risk. Stocks alone: $2.1B. Weights use the stock portfolio.
$647.3M
31.2% of stocks
No changeThis quarter-41.2%Since filed4+ qtrsHeld$367.4M
17.7% of stocks
+19%This quarter-9.7%Since filed4+ qtrsHeld$207.6M
10.0% of stocks
+7%This quarter-27.3%Since filed4+ qtrsHeld$127.2M
6.1% of stocks
+6%This quarter+3.3%Since filed3 qtrsHeld$84.5M
4.1% of stocks
No changeThis quarter+27.1%Since filed4+ qtrsHeld$78.2M
3.8% of stocks
+4%This quarter-13.3%Since filed3 qtrsHeld$58.5M
2.8% of stocks
+94%This quarter-65.4%Since filed4+ qtrsHeldAIQualityAI quality score is Pro: unlock with a free trialEst. buyEstimated buy price is Pro: unlock with a free trialAdded 3 qtrs in a row$53.7M
2.6% of stocks
-36%This quarter-42.6%Since filed4+ qtrsHeld$47.9M
2.3% of stocks
+20%This quarter+16.8%Since filed4+ qtrsHeldAIQualityAI quality score is Pro: unlock with a free trialEst. buyEstimated buy price is Pro: unlock with a free trialAdded 3 qtrs in a row$46.7M
2.3% of stocks
No changeThis quarter-17.7%Since filed2 qtrsHeld
All holdings — Caligan Partners LP (Q2 2026)
28 disclosed positions from the Form 13F-HR on SEC EDGAR, with quarter-over-quarter share changes. Largest by value first; the ten above are not repeated.
| # | Company | Held | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 11 | Revolution Medicines, Inc. | Healthcare | $47.2M | — | 252K | +10% | — | — | 13F | |
| 12 | Immunocore Holdings plcadr | Healthcare | $43.9M | 2.1% | 1.38M | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 13 | Viridian Therapeutics, Inc.\DE | Healthcare | $40.3M | 1.9% | 2.19M | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 14 | Vor Biopharma Inc. | Healthcare | $35.4M | 1.7% | 1.93M | — | 3 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 15 | SAB Biotherapeutics, Inc. | Healthcare | $31.1M | 1.5% | 7.97M | — | 2 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 16 | Inventiva S.A.adr | Healthcare | $30.9M | 1.5% | 8.16M | +64% | 3 qtrsAdded 3 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 17 | Aura Biosciences, Inc. | Healthcare | $30.5M | 1.5% | 4.30M | +1770% | 2 qtrsAdded 2 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 18 | Tyra Biosciences, Inc. | Healthcare | $25.8M | 1.2% | 807K | -37% | 4+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 19 | Opus Genetics, Inc. | Healthcare | $25.0M | 1.2% | 6.08M | +0.0% | 2 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 20 | Anika Therapeutics, Inc. | Healthcare | $21.0M | 1.0% | 1.44M | — | 4+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 21 | Sagimet Biosciences Inc. | Healthcare | $19.3M | 0.9% | 2.50M | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 22 | Artiva Biotherapeutics, Inc. | Healthcare | $16.8M | 0.8% | 1.74M | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 23 | — | FAETH THERAPEUTICS INC - COM NEW | — | $15.7M | 0.8% | 629K | +400% | — | — | 13F |
| 24 | MBX Biosciences, Inc. | Healthcare | $11.0M | 0.5% | 200K | -76% | 2 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 25 | Verrica Pharmaceuticals Inc. | Healthcare | $5.7M | 0.3% | 924K | — | 4+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 26 | $AGIO CALL | AGIOS PHARMACEUTICALS, INC. | Healthcare | $3.3M | — | 90K | — | |||
| 27 | $ADMA CALL | ADMA BIOLOGICS, INC. | Healthcare | $2.5M | — | 300K | — | |||
| 28 | $CLRB | Cellectar Biosciences, Inc. | Healthcare | $1.3M | 0.1% | 470K | New |
What changed in Q2 2026
Against the previous quarter's 13F: 5 new, 11 added to, 3 trimmed, 5 sold out. Share-count changes; largest moves by dollar size first.
New positions (5)
$IMCRImmunocore Holdings plc$43.9M
first bought this quarter
$VRDNViridian Therapeutics, Inc.\DE$40.3M
first bought this quarter
$SGMTSagimet Biosciences Inc.$19.3M
first bought this quarter
$ARTVArtiva Biotherapeutics, Inc.$16.8M
first bought this quarter
$CLRBCellectar Biosciences, Inc.$1.3M
first bought this quarter
Added to (11)
$RVMDRevolution Medicines, Inc.+19%
now $367.4M · held 4+ qtrs, 3 adds in a row
$AURAAura Biosciences, Inc.+1770%
now $30.5M · held 2 qtrs, 2 adds in a row
$AVTXAvalo Therapeutics, Inc.+94%
now $58.5M · held 4+ qtrs, 3 adds in a row
$ABVXAbivax S.A.+7%
now $207.6M · held 4+ qtrs
- FAETH THERAPEUTICS INC - COM NEW+400%
now $15.7M
$IVAInventiva S.A.+64%
now $30.9M · held 3 qtrs, 3 adds in a row
+5 more in the Excel export
Trimmed (3)
Holdings by quarter
Every 13F Caligan Partners LP has filed, 14 earlier quarters. Pick one to see what it held then.
Is it too late to follow Caligan Partners?
Q2 2026 13F filed with the SEC on Aug 14, 2026. Prices are closing prices as of Oct 26, 2026.
Average quality of Caligan Partners's top 20 holdings: 64/100 (our AI quality score, weighted by position size; 8 of the 20 are scored)
Top 10 since filing
-23.5%
Value-weighted move of the 10 largest stock positions
Turnover
13%
Last quarter
Top 10 weight
83%
Share of the stock portfolio in its 10 largest positions
Held 4+ quarters
74%
Share of portfolio value in positions held a year or more
Highest-quality names it owns(among its 100 largest positions)
The 8 highest-scoring companies in this portfolio are a Pro feature.
How these are measured
- Moves since the quarter-end and since the filing date use our own daily closing prices, from the close on (or just before) each date to the latest close.
- Turnover is the lesser of shares bought or sold in a quarter, valued at the quarter-end prices in the 13F, divided by the average of the two quarters' stock portfolio values.
- Quarters held and add/trim streaks count back only through quarters whose filed holdings add up to the filing's own cover-page total (back to Q3 2025 for this fund). A change counts as an add or a trim when the split-adjusted share count moves by more than 1%.
- Estimate, not the fund's reported cost. For each quarter in the current holding period in which the fund's share count rose (split-adjusted), we take that quarter's average daily close and weight it by the shares added; sales do not change an average cost. Quarters where the stock's price history and the 13F's own implied price disagree by more than 2x are left out.
- Put and call option rows report the value of the underlying shares, not a position the fund paid for, so they are left out of all of the above.
Portfolio Overview
Caligan Partners LP disclosed 28 positions worth $2.1B in its Form 13F-HR for Q2 2026 — $2.1B in common stock plus $53.0M of put/call option positions (reported at underlying notional value, not premium at risk), led by $LQDA (Liquidia Corp) at 31.2% of the equity portfolio, followed by $RVMD and $ABVX. During the quarter the fund opened 5 new positions and exited 5 — including a new stake in $IMCR and a full exit from $MLYS. The portfolio is most concentrated in Healthcare (99.2% of disclosed assets). All figures are sourced directly from Caligan Partners LP’s Form 13F-HR filing with the SEC under CIK 1727492.
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AI-Powered Hedge Fund Analysis: Caligan Partners LP
13F Pro is an AI hedge fund tracker and stock research platform. For Caligan Partners LP (SEC CIK: 1727492), the platform ingests every quarterly Form 13F filing and applies AI-powered analysis on top — 10 specialized AI analysts (value, growth, momentum, macro, activist, and more) debate the fund's top positions and publish AI-generated analysis with cited SEC sources.
Every holding in Caligan Partners LP's portfolio is scored on an AI quality ranking built from its SEC filings (ROIC, FCF margin, revenue growth, institutional flow, earnings quality, shareholder dilution, and more). Track accumulation and distribution quarter over quarter, identify conviction positions, and see AI stock analysis for each position — alongside 8,700+ other institutional filers and 2,800+ AI-ranked companies.