SPRUCE BIOSCIENCES, INC.(SPRB)Stock Analysis
AI analysis on 2,800+ stocks →Deep AI analysis on 2,800+ stocks →13F Pro Quality Score
Not in ranked universe
Below size threshold
Below the main board's size threshold of $25M annual revenue or $100M total assets. This company reported $10.1M in revenue and is scored on the micro-cap board instead.
Financial data, filings, and institutional holdings below are still tracked in full — only the proprietary quality composite is unavailable for this name.
SPRB Stock Analysis & AI Quality Score
Data updated 2026-07-26AI stock analysis and institutional research for SPRUCE BIOSCIENCES, INC. (SPRB), a Healthcare sector company. SPRB is not currently included in 13F Pro's AI-ranked quality universe — below the main board's size threshold of $25m annual revenue or $100m total assets. this company reported $10.1m in revenue and is scored on the micro-cap board instead. Based on the latest XBRL financial filings (Q2 2026), SPRUCE BIOSCIENCES, INC. reports net income of $-16.2M, free cash flow of $-22.3M. Top institutional holders of SPRB by reported 13-F value include AIGH Capital Management, ORBIMED ADVISORS, BlackRock, based on the most recent SEC filings. SPRB trades on the Nasdaq exchange and files with the SEC under CIK 1683553. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate SPRB daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for SPRUCE BIOSCIENCES, INC. directly from SEC EDGAR.
Net Income
Q2 2026
$-16.2M
Free Cash Flow
Q2 2026
$-22.3M
ROIC
Q2 2026
-62.2%
Revenue & Net Income
Earnings Per Share
Key Financials Over Time
Export Financial Table · ProRevenue
-100.0% YoYNet Income
+26.5% YoYOperating Income
+35.0% YoYEPS (Diluted)
+47.3% YoYTotal Assets
+17.3% YoYTotal Debt
-100.0% YoYOp. Cash Flow
+40.4% YoYFree Cash Flow
| Metric | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 |
|---|---|---|---|---|---|---|
| Revenue | $0.00 -100.0% | $4.9M -51.3% | $10.1M | $0.00 | — | — |
| Net Income | $-39.0M +26.5% | $-53.0M -10.7% | $-47.9M -3.8% | $-46.2M -9.2% | $-42.3M -43.2% | $-29.5M |
| Operating Income | $-36.5M +35.0% | $-56.2M -8.0% | $-52.0M -10.0% | $-47.3M -12.4% | $-42.1M -43.0% | $-29.4M |
| EPS (Diluted) | $-50.83 +47.3% | $-96.40 -7674.2% | $-1.24 +36.7% | $-1.96 -8.3% | $-1.81 | — |
| Total Assets | $53.0M +17.3% | $45.2M -56.5% | $103.9M +21.4% | $85.6M -32.3% | $126.5M -22.3% | $162.9M |
| Total Debt | $0.00 -100.0% | $3.5M -35.1% | $5.3M -26.6% | $7.3M +48.9% | $4.9M -30.6% | $7.0M |
| Operating Cash Flow | $-33.3M +40.4% | $-56.0M -68.2% | $-33.3M +20.2% | $-41.7M -16.2% | $-35.9M -30.4% | $-27.5M |
| Free Cash Flow | — | $-56.0M -68.2% | $-33.3M +20.2% | $-41.7M -15.9% | $-36.0M -30.4% | $-27.6M |
Get alerted when SPRB's score changes
Free account: watchlist tracking, the daily AI brief, and the AI screener.
Available Research
13F Pro tracks comprehensive data for SPRUCE BIOSCIENCES, INC. including:
Top Institutional Holders of SPRB
AIGH Capital Management LLC
$13.5M250,000 shORBIMED ADVISORS LLC
$10.8M200,000 shBlackRock, Inc.
$10.1M187,836 shMILLENNIUM MANAGEMENT LLC
$8.7M160,981 shAWM Investment Company, Inc.
$7.9M146,988 shIkarian Capital, LLC
$6.6M121,356 shVANGUARD CAPITAL MANAGEMENT LLC
$6.4M119,331 shAlyeska Investment Group, L.P.
$4.4M81,671 shGEODE CAPITAL MANAGEMENT, LLC
$3.8M70,548 shADAR1 Capital Management, LLC
$3.7M67,717 sh
| Fund | Value | Shares |
|---|---|---|
| AIGH Capital Management LLC | $13.5M | 250,000 |
| ORBIMED ADVISORS LLC | $10.8M | 200,000 |
| BlackRock, Inc. | $10.1M | 187,836 |
| MILLENNIUM MANAGEMENT LLC | $8.7M | 160,981 |
| AWM Investment Company, Inc. | $7.9M | 146,988 |
| Ikarian Capital, LLC | $6.6M | 121,356 |
| VANGUARD CAPITAL MANAGEMENT LLC | $6.4M | 119,331 |
| Alyeska Investment Group, L.P. | $4.4M | 81,671 |
| GEODE CAPITAL MANAGEMENT, LLC | $3.8M | 70,548 |
| ADAR1 Capital Management, LLC | $3.7M | 67,717 |
More Healthcare Companies
View all Healthcare →Put SPRB on your watchlist
Track score changes the day SPRUCE BIOSCIENCES, INC. files with the SEC, follow the hedge funds that own it, screen 2,800+ AI-scored stocks, and get the daily brief — free.
Free tier includes 13F data, economic indicators, and market overview. Pro starts at $6.67/mo (billed annually).
Popular Research
Is SPRB a good stock to buy?
13F Pro's AI-powered analysis of SPRUCE BIOSCIENCES, INC. (SPRB) draws on SEC EDGAR-sourced fundamentals, institutional 13F holdings, and insider Form 4 transactions in the Healthcare sector (listed on Nasdaq). The 32-signal AI Quality Score, current rank, and full bull/bear verdict for SPRB are available on the SPRB stock profile dashboard — with the same data, AI insights, ratios, and institutional activity refreshed after every 10-K, 10-Q, 13F, and Form 4 filing. SPRB is classified as a small company.
Which hedge funds own SPRB?
Institutional investors are required to disclose their holdings quarterly via SEC Form 13F. 13F Pro aggregates these filings to show which hedge funds, mutual funds, and asset managers are buying or selling SPRB. Combined with insider transaction data from Form 4 filings and AI-powered analysis from 10 specialized research agents, 13F Pro provides a comprehensive view of SPRUCE BIOSCIENCES, INC.'s investment landscape.