Avoro Capital Advisors LLC
Sector Allocation
- Healthcare99.7%$11.1B
- Other0.3%$36.1M
AUM History
13fpro.ai/research/fund/avoro-capital-advisors-llc-1633313
Conviction and streaks
Concentrating · top 10 = 79.5%From the fund's last 12 quarters of 13F filings: positions held longest at size, and names it added to or trimmed several quarters running.
Largest positions — Q2 2026
UTHR
$1.5BASND
$1.4BKRYS
$1.1BMDGL
$984.4MARGX
$927.8MARWR
$925.6MKYMR
$857.1MRVMD
$430.2MCYTK
$425.9MCELC
$355.7MGPCR
$351.8MXENE
$348.7MDFTX
$338.2MQURE
$309.9MVERA
$245.6MTSHA
$162.7MOCUL
$123.1MDMRA
$98.4MCOAG
$70.7MGHRS
$48.4M
Top 20 stock positions. Options are left out: 13F reports them at the underlying's value.
13fpro.ai/research/fund/avoro-capital-advisors-llc-1633313
Avoro Capital Advisors LLC 13F holdings — Q2 2026
$11.1B portfolio (+9.6% QoQ) · 26 holdings · Q2 2026 13F · top 10 are 80% of the stock portfolio
$1.5B
13.5% of stocks
+6%This quarter+18.6%Since filed10+ qtrsHeld$1.4B
12.2% of stocks
+1.0%This quarter-1.4%Since filed10+ qtrsHeld$1.1B
9.6% of stocks
No changeThis quarter-5.6%Since filed10+ qtrsHeld$984.4M
8.8% of stocks
+0.8%This quarter-13.8%Since filed10+ qtrsHeld$927.8M
8.3% of stocks
No changeThis quarter+2.1%Since filed10+ qtrsHeld$925.6M
8.3% of stocks
+6%This quarter-31.9%Since filed10+ qtrsHeld$857.1M
7.7% of stocks
No changeThis quarter-2.2%Since filed10+ qtrsHeld$430.2M
3.9% of stocks
-2%This quarter-9.7%Since filed3 qtrsHeld$425.9M
3.8% of stocks
+50%This quarter-18.1%Since filed2 qtrsHeldAIQualityAI quality score is Pro: unlock with a free trialEst. buyEstimated buy price is Pro: unlock with a free trialAdded 2 qtrs in a row$355.7M
3.2% of stocks
+0.7%This quarter-28.5%Since filed3 qtrsHeld
All holdings — Avoro Capital Advisors LLC (Q2 2026)
26 disclosed positions from the Form 13F-HR on SEC EDGAR, with quarter-over-quarter share changes. Largest by value first; the ten above are not repeated.
| # | Company | Held | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 11 | Structure Therapeutics Inc.adr | Healthcare | $351.8M | 3.2% | 6.56M | — | 4 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 12 | Xenon Pharmaceuticals Inc. | Healthcare | $348.7M | 3.1% | 5.78M | — | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 13 | Definium Therapeutics, Inc. | Healthcare | $338.2M | 3.0% | 7.19M | +44% | 2 qtrsAdded 2 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 14 | uniQure N.V. | Healthcare | $309.9M | 2.8% | 6.73M | +13% | 7 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 15 | Vera Therapeutics, Inc. | Healthcare | $245.6M | 2.2% | 5.72M | -3% | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 16 | Taysha Gene Therapies, Inc. | Healthcare | $162.7M | 1.5% | 23.89M | +10% | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 17 | OCULAR THERAPEUTIX, INC | Healthcare | $123.1M | 1.1% | 12.54M | +2% | 10+ qtrsAdded 4 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 18 | Damora Therapeutics, Inc. | Healthcare | $98.4M | 0.9% | 3.78M | — | 2 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 19 | Hemab Therapeutics Holdings, Inc. | Healthcare | $70.7M | 0.6% | 1.93M | New | 1 qtr | AI quality score is Pro: unlock with a free trial | 13F | |
| 20 | GH Research PLC | Healthcare | $48.4M | 0.4% | 1.80M | — | 3 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 21 | Viridian Therapeutics, Inc.\DE | Healthcare | $45.9M | 0.4% | 2.50M | +67% | 3 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 22 | Septerna, Inc. | Healthcare | $44.8M | 0.4% | 1.34M | — | 7 qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 23 | Avalo Therapeutics, Inc. | Healthcare | $43.1M | 0.4% | 2.33M | +65% | 2 qtrsAdded 2 qtrs in a row | AI quality score is Pro: unlock with a free trial | 13F | |
| 24 | — | FAETH THERAPEUTICS INC - COMMON | — | $36.1M | 0.3% | 1.44M | New | — | — | 13F |
| 25 | Whitehawk Therapeutics, Inc. | Healthcare | $13.1M | 0.1% | 2.85M | — | 10+ qtrs | AI quality score is Pro: unlock with a free trial | 13F | |
| 26 | $LXEO | Lexeo Therapeutics, Inc. | Healthcare | $6.9M | 0.1% | 1.49M | -21% |
What changed in Q2 2026
Against the previous quarter's 13F: 2 new, 12 added to, 3 trimmed, 8 sold out. Share-count changes; largest moves by dollar size first.
New positions (2)
$COAGHemab Therapeutics Holdings, Inc.$70.7M
first bought this quarter
- FAETH THERAPEUTICS INC - COMMON$36.1M
first bought this quarter
Added to (12)
$CYTKCYTOKINETICS INC+50%
now $425.9M · held 2 qtrs, 2 adds in a row
$DFTXDefinium Therapeutics, Inc.+44%
now $338.2M · held 2 qtrs, 2 adds in a row
$UTHRUNITED THERAPEUTICS Corp+6%
now $1.5B · held 10+ qtrs
$ARWRARROWHEAD PHARMACEUTICALS, INC.+6%
now $925.6M · held 10+ qtrs
$QUREuniQure N.V.+13%
now $309.9M · held 7 qtrs
$VRDNViridian Therapeutics, Inc.\DE+67%
now $45.9M · held 3 qtrs
+6 more in the Excel export
Trimmed (3)
Sold out (8)
$APLSApellis Pharmaceuticals, Inc.was $491.7M
held 9+ qtrs
$CNTACentessa Pharmaceuticals plcwas $454.0M
held 5 qtrs
$TERNTerns Pharmaceuticals, Inc.was $300.2M
held 1 qtr
$SLNOSOLENO THERAPEUTICS INCwas $77.0M
held 9+ qtrs
$ALKSAlkermes plc.was $42.4M
$UTHRCALLUNITED THERAPEUTICS Corpwas $10.3M
+2 more in the Excel export
Holdings by quarter
Every 13F Avoro Capital Advisors LLC has filed, 41 earlier quarters. Pick one to see what it held then.
Is it too late to follow Avoro Capital Advisors?
Q2 2026 13F filed with the SEC on Aug 14, 2026. Prices are closing prices as of Oct 26, 2026.
Average quality of Avoro Capital Advisors's top 20 holdings: 47/100 (our AI quality score, weighted by position size; 10 of the 20 are scored)
Top 10 since filing
-5.1%
Value-weighted move of the 10 largest stock positions
Turnover
6%
Last quarter; 31% over the last 4
Top 10 weight
80%
Share of the stock portfolio in its 10 largest positions
Held 4+ quarters
83%
Share of portfolio value in positions held a year or more
Highest-quality names it owns(among its 100 largest positions)
The 8 highest-scoring companies in this portfolio are a Pro feature.
How these are measured
- Moves since the quarter-end and since the filing date use our own daily closing prices, from the close on (or just before) each date to the latest close.
- Turnover is the lesser of shares bought or sold in a quarter, valued at the quarter-end prices in the 13F, divided by the average of the two quarters' stock portfolio values.
- Quarters held and add/trim streaks count back only through quarters whose filed holdings add up to the filing's own cover-page total (back to Q1 2024 for this fund). A change counts as an add or a trim when the split-adjusted share count moves by more than 1%.
- Estimate, not the fund's reported cost. For each quarter in the current holding period in which the fund's share count rose (split-adjusted), we take that quarter's average daily close and weight it by the shares added; sales do not change an average cost. Quarters where the stock's price history and the 13F's own implied price disagree by more than 2x are left out.
- Put and call option rows report the value of the underlying shares, not a position the fund paid for, so they are left out of all of the above.
Portfolio Overview
Avoro Capital Advisors LLC disclosed 26 positions worth $11.1B in its Form 13F-HR for Q2 2026, led by $UTHR (UNITED THERAPEUTICS Corp) at 13.5% of the equity portfolio, followed by $ASND and $KRYS. During the quarter the fund opened 2 new positions and exited 8 — including a new stake in $COAG and a full exit from $APLS. The portfolio is most concentrated in Healthcare (99.7% of disclosed assets). All figures are sourced directly from Avoro Capital Advisors LLC’s Form 13F-HR filing with the SEC under CIK 1633313.
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AI-Powered Hedge Fund Analysis: Avoro Capital Advisors LLC
13F Pro is an AI hedge fund tracker and stock research platform. For Avoro Capital Advisors LLC (SEC CIK: 1633313), the platform ingests every quarterly Form 13F filing and applies AI-powered analysis on top — 10 specialized AI analysts (value, growth, momentum, macro, activist, and more) debate the fund's top positions and publish AI-generated analysis with cited SEC sources.
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