OPKO HEALTH, INC.(OPK)Stock Analysis
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Rank #2,683 of 2,879 stocks
Rankings refresh quarterly once 80% of peers have filed (~45 days after quarter-end). Next update: ~Aug 14, 2026.
Revenue Growth
Profitability
Balance Sheet
Earnings Quality
Free Cash Flow
Institutional Flow
Revenue Scale
Dilution Risk
OPK Stock Analysis & AI Quality Score
AI stock analysis and institutional research for OPKO HEALTH, INC. (OPK), a Healthcare sector company. 13F Pro's AI-powered ranking engine scores OPK at 20.0/100 on a 32-signal composite quality model, placing it at rank #2,683 of 2,879 stocks — the bottom half of the AI-ranked universe. Areas of concern include revenue growth (7.3) and profitability (10.9), which score below median versus the broader universe. Shareholder dilution risk is elevated at 43.2/100, reflecting ongoing share issuance or stock-based compensation. Based on the latest XBRL financial filings (Q1 2026), OPKO HEALTH, INC. reports quarterly revenue of $124.2M, net income of $-54.8M, an operating margin of -41.1%. Top institutional holders of OPK by reported 13-F value include Rubric Capital Management, BlackRock,, VANGUARD PORTFOLIO MANAGEMENT, based on the most recent SEC filings. OPK trades on the Nasdaq exchange and files with the SEC under CIK 944809. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate OPK daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for OPKO HEALTH, INC. directly from SEC EDGAR. OPKO HEALTH, INC.'s 13F Pro composite quality score has ranged between 8 and 61 since 2021, currently 20.0 — a declining long-term trajectory across 56 quarterly and live scoring snapshots.
Revenue
Q1 2026
$124.2M
Net Income
Q1 2026
$-54.8M
Free Cash Flow
Q1 2026
$-21.1M
Operating Margin
Q1 2026
-41.1%
D/E Ratio
Q1 2026
0.29
Revenue & Net Income
Earnings Per Share
Key Financials Over Time
Export Financial Table · Pro+Revenue
-29.0% YoYNet Income
+83.8% YoYOperating Income
+32.8% YoYEPS (Diluted)
+82.6% YoYTotal Assets
+1.5% YoYTotal Debt
+239.0% YoYOp. Cash Flow
-92.8% YoY| Metric | FY 2024 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 |
|---|---|---|---|---|---|---|
| Revenue | $713.1M -29.0% | $1.00B -43.4% | $1.77B +23.6% | $1.44B +59.1% | $901.9M -8.9% | $990.3M |
| Net Income | $-53.22B +83.8% | $-328.40B -989.5% | $-30.14B -98651.6% | $30.6M +109.7% | $-314.9M -105.8% | $-153.0M |
| Operating Income | $-152.1M +32.8% | $-226.3M -1306.7% | $18.8M -67.5% | $57.7M +121.1% | $-274.1M -60.1% | $-171.2M |
| EPS (Diluted) | $-0.08 +82.6% | $-0.46 -820.0% | $-0.05 -200.0% | $0.05 +109.4% | $-0.53 -96.3% | $-0.27 |
| Total Assets | $2.20B +1.5% | $2.17B -9.7% | $2.40B -3.0% | $2.47B +7.1% | $2.31B -5.8% | $2.45B |
| Total Debt | $874.4M +239.0% | $258.0M +25.7% | $205.3M -18.3% | $251.2M -7.1% | $270.3M +2473.1% | $10.5M |
| Operating Cash Flow | $-183.5M -92.8% | $-95.2M -348.3% | $38.3M -2.9% | $39.5M +122.9% | $-172.5M -58.1% | $-109.1M |
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Top Institutional Holders of OPK
Rubric Capital Management LP
$54.5M47,791,243 shBlackRock, Inc.
$41.3M36,232,223 shVANGUARD PORTFOLIO MANAGEMENT LLC
$16.8M14,769,719 shVANGUARD CAPITAL MANAGEMENT LLC
$16.5M14,499,164 shWOLVERINE ASSET MANAGEMENT LLC
$16.2M12,950,000 shGEODE CAPITAL MANAGEMENT, LLC
$12.9M11,301,501 shWhitefort Capital Management, LP
$11.6M9,350,000 shSTATE STREET CORP
$10.8M9,501,377 shPenderFund Capital Management Ltd.
$9.2M7,311,000 shGOLDMAN SACHS GROUP INC
$8.7M7,675,026 sh
| Fund | Value | Shares |
|---|---|---|
| Rubric Capital Management LP | $54.5M | 47,791,243 |
| BlackRock, Inc. | $41.3M | 36,232,223 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $16.8M | 14,769,719 |
| VANGUARD CAPITAL MANAGEMENT LLC | $16.5M | 14,499,164 |
| WOLVERINE ASSET MANAGEMENT LLC | $16.2M | 12,950,000 |
| GEODE CAPITAL MANAGEMENT, LLC | $12.9M | 11,301,501 |
| Whitefort Capital Management, LP | $11.6M | 9,350,000 |
| STATE STREET CORP | $10.8M | 9,501,377 |
| PenderFund Capital Management Ltd. | $9.2M | 7,311,000 |
| GOLDMAN SACHS GROUP INC | $8.7M | 7,675,026 |
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Popular Research
Is OPK a good stock to buy?
13F Pro's AI-powered analysis of OPKO HEALTH, INC. (OPK) draws on SEC EDGAR-sourced fundamentals, institutional 13F holdings, and insider Form 4 transactions in the Healthcare sector (listed on Nasdaq). The 32-signal AI Quality Score, current rank, and full bull/bear verdict for OPK are available on the OPK stock profile dashboard — with the same data, AI insights, ratios, and institutional activity refreshed after every 10-K, 10-Q, 13F, and Form 4 filing.
Which hedge funds own OPK?
Institutional investors are required to disclose their holdings quarterly via SEC Form 13F. 13F Pro aggregates these filings to show which hedge funds, mutual funds, and asset managers are buying or selling OPK. Combined with insider transaction data from Form 4 filings and AI-powered analysis from 10 specialized research agents, 13F Pro provides a comprehensive view of OPKO HEALTH, INC.'s investment landscape.