Zentalis Pharmaceuticals, Inc. (ZNTL) — Institutional Holders, Q2 2026
115 institutional investment managers reported a ZNTL position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $228.9M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
ZNTL in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- BlackRockAdded · +2,483,688 sh+$12.0M
- ORBIMED ADVISORSNew · +1,390,576 sh+$6.7M
- Soleus Capital Management, L.P.New · +950,000 sh+$4.6M
- GEODE CAPITAL MANAGEMENTAdded · +663,081 sh+$3.2M
- STATE STREETAdded · +637,726 sh+$3.1M
Biggest sellers
- D. E. ShawTrimmed · -937,532 sh-$4.5M
- MILLENNIUM MANAGEMENTTrimmed · -625,541 sh-$3.0M
- Almitas CapitalSold out · -610,073 sh-$3.0M
- JANE STREET GROUPTrimmed · -475,944 sh-$2.3M
- BNP PARIBAS FINANCIAL MARKETSTrimmed · -458,959 sh-$2.2M
ZNTL 13F holders ranked 1–100 of 115
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | 5AM Venture Management#1 · 3,947,913 sh | 3,947,913 | $19.1M | 6.65% | 0.0% |
| 2 | BlackRock#2 · 3,753,525 sh | 3,753,525 | $18.2M | <0.01% | +195.6% |
| 3 | Squadron Capital Management#3 · 3,700,000 sh | 3,700,000 | $17.9M | 5.57% | +1.9% |
| 4 | TWO SIGMA INVESTMENTS#4 · 3,024,936 sh | 3,024,936 | $14.7M | 0.01% | +2.3% |
| 5 | VANGUARD CAPITAL MANAGEMENT#5 · 2,835,669 sh | 2,835,669 | $13.8M | <0.01% | +22.7% |
| 6 | ACADIAN ASSET MANAGEMENT#6 · 2,681,900 sh | 2,681,900 | $13.0M | 0.02% | -5.8% |
| 7 | CITADEL ADVISORS#7 · 2,298,403 sh | 2,298,403 | $11.1M | <0.01% | +32.7% |
| 8 | RENAISSANCE TECHNOLOGIES#8 · 1,609,078 sh | 1,609,078 | $7.8M | 0.01% | -17.0% |
| 9 | Opaleye Management#9 · 1,412,656 sh | 1,412,656 | $6.9M | 0.62% | 0.0% |
| 10 | ORBIMED ADVISORS#10 · 1,390,576 sh | 1,390,576 | $6.7M | 0.13% | New |
| 11 | Decheng Capital#11 · 1,323,327 sh | 1,323,327 | $6.4M | 0.88% | 0.0% |
| 12 | GEODE CAPITAL MANAGEMENT#12 · 1,284,117 sh | 1,284,117 | $6.2M | <0.01% | +106.8% |
| 13 | BANK OF AMERICA#13 · 1,114,650 sh | 1,114,650 | $5.4M | <0.01% | -1.6% |
| 14 | Ishara Investments#14 · 1,025,000 sh | 1,025,000 | $5.0M | 3.65% | -16.7% |
| 15 | PRIMECAP MANAGEMENT#15 · 957,420 sh | 957,420 | $4.6M | <0.01% | 0.0% |
| 16 | Soleus Capital Management, L.P.#16 · 950,000 sh | 950,000 | $4.6M | 0.16% | New |
| 17 | STATE STREET#17 · 887,416 sh | 887,416 | $4.3M | <0.01% | +255.4% |
| 18 | VANGUARD PORTFOLIO MANAGEMENT#18 · 808,548 sh | 808,548 | $3.9M | <0.01% | +124.2% |
| 19 | PFIZER#19 · 953,834 sh | 953,834 | $3.9M | 2.26% | 0.0% |
| 20 | Connor, Clark & Lunn Investment Management Ltd.#20 · 758,033 sh | 758,033 | $3.7M | <0.01% | -4.3% |
| 21 | MILLENNIUM MANAGEMENT#21 · 664,281 sh | 664,281 | $3.2M | <0.01% | -48.5% |
| 22 | ADAR1 Capital Management#22 · 652,750 sh | 652,750 | $3.2M | 0.14% | +351.3% |
| 23 | MARSHALL WACE, LLP#23 · 591,473 sh | 591,473 | $2.9M | <0.01% | +50.6% |
| 24 | Qube Research & Technologies Ltd#24 · 574,806 sh | 574,806 | $2.8M | <0.01% | -9.8% |
| 25 | D. E. Shaw#25 · 546,566 sh | 546,566 | $2.7M | <0.01% | -63.2% |
| 26 | DIMENSIONAL FUND ADVISORS#26 · 542,852 sh | 542,852 | $2.6M | <0.01% | +99.6% |
| 27 | MORGAN STANLEY#27 · 471,250 sh | 471,250 | $2.3M | <0.01% | +34.6% |
| 28 | NORTHERN#28 · 388,299 sh | 388,299 | $1.9M | <0.01% | +228.5% |
| 29 | GSA CAPITAL PARTNERS LLP#29 · 374,260 sh | 374,260 | $1.8M | 0.11% | -39.7% |
| 30 | GOLDMAN SACHS GROUP#30 · 372,564 sh | 372,564 | $1.8M | <0.01% | -19.5% |
| 31 | VANGUARD FIDUCIARY#31 · 336,940 sh | 336,940 | $1.6M | <0.01% | +10.7% |
| 32 | FMR#32 · 310,264 sh | 310,264 | $1.5M | <0.01% | +9.3% |
| 33 | Seven Fleet Capital Management#33 · 317,600 sh | 317,600 | $1.5M | 0.24% | +188.7% |
| 34 | UBS Group AG#34 · 297,378 sh | 297,378 | $1.4M | <0.01% | +91.0% |
| 35 | XTX Topco Ltd#35 · 289,693 sh | 289,693 | $1.4M | 0.02% | -10.2% |
| 36 | Creative Planning#36 · 285,000 sh | 285,000 | $1.4M | <0.01% | 0.0% |
| 37 | SEI INVESTMENTS#37 · 256,079 sh | 256,079 | $1.2M | <0.01% | +33.7% |
| 38 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#38 · 215,113 sh | 215,113 | $1.0M | <0.01% | -62.3% |
| 39 | Peapod Lane Capital#39 · 202,864 sh | 202,864 | $983.9K | — | -44.7% |
| 40 | CDC Financial#40 · 177,762 sh | 177,762 | $862.1K | 0.36% | -37.4% |
| 41 | CHARLES SCHWAB INVESTMENT MANAGEMENT#41 · 171,911 sh | 171,911 | $833.8K | <0.01% | +236.5% |
| 42 | Invesco Ltd.#42 · 161,657 sh | 161,657 | $784.0K | <0.01% | +28.5% |
| 43 | Stonepine Capital Management#43 · 161,583 sh | 161,583 | $783.7K | 0.37% | -40.0% |
| 44 | BARCLAYS PLC#44 · 158,856 sh | 158,856 | $770.5K | <0.01% | -73.1% |
| 45 | Informed Momentum#45 · 126,863 sh | 126,863 | $615.3K | 0.05% | New |
| 46 | Quarry#46 · 125,114 sh | 125,114 | $606.8K | 0.05% | -16.6% |
| 47 | Bank of New York Mellon#47 · 122,068 sh | 122,068 | $592.0K | <0.01% | New |
| 48 | Susquehanna Portfolio Strategies#48 · 112,122 sh | 112,122 | $543.8K | <0.01% | New |
| 49 | BARR E S#49 · 110,000 sh | 110,000 | $533.5K | 0.03% | 0.0% |
| 50 | FEDERATED HERMES#50 · 98,617 sh | 98,617 | $478.3K | <0.01% | +50.5% |
| 51 | AMERICAN CENTURY COMPANIES#51 · 97,757 sh | 97,757 | $474.1K | <0.01% | +101.3% |
| 52 | SIMPLEX TRADING#52 · 78,904 sh | 78,904 | $382.7K | <0.01% | -19.9% |
| 53 | BRIDGEWAY CAPITAL MANAGEMENT#53 · 77,300 sh | 77,300 | $374.9K | <0.01% | 0.0% |
| 54 | ExodusPoint Capital Management#54 · 74,966 sh | 74,966 | $363.6K | <0.01% | New |
| 55 | WEALTH ENHANCEMENT ADVISORY SERVICES#55 · 68,816 sh | 68,816 | $335.8K | — | -12.6% |
| 56 | Nuveen#56 · 66,674 sh | 66,674 | $323.4K | <0.01% | New |
| 57 | COMMONWEALTH EQUITY SERVICES#57 · 61,412 sh | 61,412 | $297.9K | <0.01% | 0.0% |
| 58 | RHUMBLINE ADVISERS#58 · 55,760 sh | 55,760 | $270.4K | <0.01% | New |
| 59 | DEUTSCHE BANK AG\#59 · 48,806 sh | 48,806 | $236.7K | <0.01% | New |
| 60 | WELLS FARGO & COMPANY#60 · 41,898 sh | 41,898 | $203.2K | 0.00% | New |
| 61 | PRICE T ROWE ASSOCIATES#61 · 41,049 sh | 41,049 | $200.0K | 0.00% | New |
| 62 | Verdad Advisers#62 · 39,608 sh | 39,608 | $192.1K | 0.18% | New |
| 63 | Quadrature Capital Ltd#63 · 37,613 sh | 37,613 | $182.4K | <0.01% | +12.8% |
| 64 | Private Advisor Group#64 · 36,472 sh | 36,472 | $176.9K | <0.01% | +15.9% |
| 65 | MetLife Investment Management#65 · 30,095 sh | 30,095 | $146.0K | <0.01% | New |
| 66 | RBF Capital#66 · 30,000 sh | 30,000 | $145.5K | <0.01% | -40.0% |
| 67 | Regency Capital Management \DE#67 · 29,500 sh | 29,500 | $143.1K | 0.06% | 0.0% |
| 68 | Marquette Asset Management#68 · 28,973 sh | 28,973 | $140.5K | — | New |
| 69 | SUSQUEHANNA FUNDAMENTAL INVESTMENTS#69 · 25,962 sh | 25,962 | $125.9K | <0.01% | New |
| 70 | TORONTO DOMINION BANK#70 · 23,566 sh | 23,566 | $114.3K | <0.01% | New |
| 71 | CITIGROUP#71 · 23,112 sh | 23,112 | $112.1K | 0.00% | -70.1% |
| 72 | MIRAE ASSET GLOBAL ETFS Ltd.#72 · 23,037 sh | 23,037 | $111.7K | <0.01% | New |
| 73 | RAYMOND JAMES FINANCIAL#73 · 22,785 sh | 22,785 | $110.5K | 0.00% | -0.5% |
| 74 | Graham Capital Management, L.P.#74 · 22,358 sh | 22,358 | $108.4K | <0.01% | -75.8% |
| 75 | Vanguard Global Advisers#75 · 21,725 sh | 21,725 | $105.4K | 0.00% | 0.0% |
| 76 | JPMORGAN CHASE#76 · 22,439 sh | 22,439 | $103.4K | 0.00% | -80.2% |
| 77 | Carson Advisory#77 · 21,170 sh | 21,170 | $102.7K | 0.05% | -9.0% |
| 78 | Sivia Capital Partners#78 · 20,000 sh | 20,000 | $97.0K | 0.01% | 0.0% |
| 79 | State of Wyoming#79 · 18,756 sh | 18,756 | $91.0K | <0.01% | -34.1% |
| 80 | Jump Financial#80 · 17,809 sh | 17,809 | $86.4K | <0.01% | New |
| 81 | EVERGREEN CAPITAL MANAGEMENT#81 · 17,429 sh | 17,429 | $84.5K | — | +3.0% |
| 82 | NEW YORK STATE COMMON RETIREMENT FUND#82 · 15,500 sh | 15,500 | $75.2K | <0.01% | New |
| 83 | Police & Firemen's Retirement System of New Jersey#83 · 14,755 sh | 14,755 | $71.6K | <0.01% | New |
| 84 | JANE STREET GROUP#84 · 14,395 sh | 14,395 | $69.8K | 0.00% | -97.1% |
| 85 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#85 · 14,289 sh | 14,289 | $69.3K | <0.01% | New |
| 86 | PRELUDE CAPITAL MANAGEMENT#86 · 13,843 sh | 13,843 | $67.1K | <0.01% | -32.1% |
| 87 | Scientech Research#87 · 13,613 sh | 13,613 | $66.0K | 0.05% | New |
| 88 | Squarepoint Ops#88 · 13,487 sh | 13,487 | $65.4K | <0.01% | -56.1% |
| 89 | OPPENHEIMER#89 · 12,656 sh | 12,656 | $61.4K | — | New |
| 90 | Spark Investment Management#90 · 12,500 sh | 12,500 | $60.6K | 0.12% | New |
| 91 | BNP PARIBAS FINANCIAL MARKETS#91 · 12,479 sh | 12,479 | $60.5K | 0.00% | -97.4% |
| 92 | nVerses Capital#92 · 10,958 sh | 10,958 | $53.1K | 0.08% | New |
| 93 | INTECH INVESTMENT MANAGEMENT#93 · 10,460 sh | 10,460 | $50.7K | <0.01% | New |
| 94 | Cornerstone Wealth Management#94 · 10,186 sh | 10,186 | $49.4K | <0.01% | 0.0% |
| 95 | Universal- Beteiligungs- und Servicegesellschaft mbH#95 · 10,096 sh | 10,096 | $49.0K | <0.01% | -55.0% |
| 96 | ALLIANCEBERNSTEIN L.P.#96 · 17,100 sh | 17,100 | $40.0K | 0.00% | New |
| 97 | Legal & General Group Plc#97 · 4,848 sh | 4,848 | $23.5K | 0.00% | New |
| 98 | Integrated Wealth Concepts#98 · 4,816 sh | 4,816 | $23.4K | <0.01% | New |
| 99 | Ameritas Investment Partners#99 · 4,540 sh | 4,540 | $22.0K | <0.01% | New |
| 100 | Russell Investments Group, Ltd.#100 · 4,000 sh | 4,000 | $19.4K | 0.00% | New |
Funds that sold out of ZNTL in Q2 2026 (19)
Held ZNTL at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Almitas Capital610,073 sh | 610,073 | $1.4M |
| Woodline Partners266,032 sh | 266,032 | $622.5K |
| PANAGORA ASSET MANAGEMENT139,690 sh | 139,690 | $326.9K |
| Hudson Bay Capital Management117,127 sh | 117,127 | $274.1K |
| Point72 Asset Management, L.P.94,854 sh | 94,854 | $222.0K |
| 49 WEALTH MANAGEMENT66,401 sh | 66,401 | $155.4K |
| HRT FINANCIAL52,185 sh | 52,185 | $122.0K |
| OMERS ADMINISTRATION47,700 sh | 47,700 | $111.6K |
| Brevan Howard Capital Management47,063 sh | 47,063 | $110.1K |
| TUDOR INVESTMENT ET AL34,849 sh | 34,849 | $81.5K |
| Headlands Technologies29,899 sh | 29,899 | $70.0K |
| AQR CAPITAL MANAGEMENT22,675 sh | 22,675 | $53.1K |
| PRUDENTIAL FINANCIAL20,850 sh | 20,850 | $48.8K |
| Schonfeld Strategic Advisors20,600 sh | 20,600 | $48.2K |
| Birchview Capital17,503 sh | 17,503 | $41.0K |
| Catalyst Funds Management Pty Ltd16,700 sh | 16,700 | $39.1K |
| CTC Alternative Strategies, Ltd.12,500 sh | 12,500 | $29.3K |
| Shay Capital10,662 sh | 10,662 | $24.9K |
| GROUP ONE TRADING, L.P.1,460 sh | 1,460 | $3.4K |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.