Septerna, Inc. (SEPN) — Institutional Holders, Q2 2026 (page 2)

154 institutional investment managers reported a SEPN position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $1.6B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 101 to 154. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

SEPN 13F holders ranked 101–154 of 154

Institutional investors reporting a position in Septerna, Inc. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
InstitutionValueQoQ
VANGUARD ASSET MANAGEMENT, Ltd#101 · 7,420 sh$248.5K0.0%
Quantinno Capital Management#102 · 7,330 sh$245.5KNew
CIBC Bancorp USA#103 · 7,222 sh$241.9KNew
Rangeley Capital#104 · 7,200 sh$241.1K-81.9%
OCCUDO QUANTITATIVE STRATEGIES#105 · 7,191 sh$240.8KNew
WINTON GROUP Ltd#106 · 7,182 sh$240.5K-18.8%
Police & Firemen's Retirement System of New Jersey#107 · 6,527 sh$218.6K+26.1%
CITADEL ADVISORS#108 · 6,350 sh$212.7KNew
MANUFACTURERS LIFE INSURANCE COMPANY, THE#109 · 6,304 sh$211.1KNew
CAPTRUST FINANCIAL ADVISORS#110 · 6,211 sh$208.0KNew
STATE OF WISCONSIN INVESTMENT BOARD#111 · 6,095 sh$204.1KNew
Chung Wu Investment Group#112 · 4,800 sh$160.8KNew
Vanguard Investments Australia, Ltd.#113 · 3,895 sh$130.4K0.0%
KLP KAPITALFORVALTNING AS#114 · 2,500 sh$83.7K0.0%
Covestor Ltd#115 · 2,123 sh$72.0K-6.1%
ROYAL BANK OF CANADA#116 · 2,098 sh$70.0KNew
Mirae Asset Global Investments , Ltd.#117 · 2,016 sh$67.5K-13.7%
Ameritas Investment Partners#118 · 1,944 sh$65.1K0.0%
NEW YORK STATE TEACHERS RETIREMENT SYSTEM#119 · 1,946 sh$65.0KNew
Steward Partners Investment Advisory#120 · 1,325 sh$44.4KNew
GAMMA Investing#121 · 1,119 sh$37.5K+0.8%
Tower Research Capital (TRC)#122 · 1,059 sh$35.5K+47.7%
Zurcher Kantonalbank (Zurich Cantonalbank)#123 · 971 sh$32.5K+91.1%
SIGNATUREFD#124 · 966 sh$32.4K0.0%
GF FUND MANAGEMENT LTD.#125 · 950 sh$31.8K-5.6%
NISA INVESTMENT ADVISORS#126 · 768 sh$25.7K-8.7%
Quantbot Technologies#127 · 515 sh$17.2KNew
Nikko Asset Management Americas#128 · 507 sh$16.9KNew
BNP Paribas Asset Management Holding S.A.#129 · 362 sh$12.1KNew
Pinnacle Wealth Planning Services#130 · 322 sh$10.8K0.0%
Versant Capital Management#131 · 261 sh$8.7K0.0%
SRS Capital Advisors#132 · 236 sh$7.9KNew
US BANCORP \DE\#133 · 220 sh$7.4K+11.7%
Sterling Capital Management#134 · 200 sh$6.7K-71.9%
Larson Financial Group#135 · 196 sh$6.6K-3.9%
N.E.W. Advisory Services#136 · 180 sh$6.0K0.0%
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#137 · 155 sh$5.2K0.0%
MassMutual Private Wealth & , FSB#138 · 104 sh$3.5K-23.0%
Aster Capital Management (DIFC) Ltd#139 · 102 sh$3.4KNew
Caitong International Asset Management , Ltd#140 · 77 sh$2.6K+102.6%
EverSource Wealth Advisors#141 · 64 sh$2.1K-94.5%
SBI Securities , Ltd.#142 · 55 sh$1.8K0.0%
Cornerstone Financial Management#143 · 52 sh$1.7K0.0%
Integrated Wealth Concepts#144 · 51 sh$1.7KNew
PNC FINANCIAL SERVICES GROUP#145 · 45 sh$1.5K+4.7%
ROTHSCHILD INVESTMENT#146 · 30 sh$1.0K0.0%
Fortitude Family Office#147 · 20 sh$670.000.0%
Ameritas Advisory Services#148 · 18 sh$603.00New
NATIONAL BANK OF CANADA#149 · 7 sh$234.00New
SJS Investment Consulting#150 · 6 sh$201.00New
Global Retirement Partners#151 · 3 sh$100.00—
Allworth Financial#152 · 1 sh$34.00-94.1%
Silver Grove Financial Group#153 · 1 sh$33.00New
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM#154 · 10,866 sh—+839.2%

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.