RAPT Therapeutics, Inc. (RAPT) — Institutional Holders, Q4 2025
106 institutional investment managers reported a RAPT position on SEC Form 13F-HR for the quarter ended December 31, 2025, with a combined reported value of $1.0B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
RAPT in Q4 2025: what funds did
Funds that filed a 13F for both Q3 2025 and Q4 2025, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- FCPM III SERVICES B.V.Added · +1,489,096 sh+$50.4M
- Frazier Life Sciences Management, L.P.New · +983,333 sh+$33.3M
- TCG Crossover ManagementAdded · +946,133 sh+$32.0M
- BRAIDWELLNew · +929,694 sh+$31.5M
- Siren, L.L.C.Added · +794,534 sh+$26.9M
Biggest sellers
- Deep Track CapitalTrimmed · -640,974 sh-$21.7M
- BOONE CAPITAL MANAGEMENTTrimmed · -312,005 sh-$10.6M
- SummitTX Capital, L.P.Sold out · -91,912 sh-$3.1M
- AMERIPRISE FINANCIALSold out · -51,406 sh-$1.7M
- BALYASNY ASSET MANAGEMENT L.P.Sold out · -50,348 sh-$1.7M
RAPT 13F holders ranked 1–100 of 106
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q3 2025 |
|---|---|---|---|---|---|
| 1 | Medicxi Ventures Management (Jersey) Ltd#1 · 2,794,000 sh | 2,794,000 | $94.6M | — | 0.0% |
| 2 | TCG Crossover Management#2 · 2,582,408 sh | 2,582,408 | $87.5M | — | +57.8% |
| 3 | FCPM III SERVICES B.V.#3 · 1,833,333 sh | 1,833,333 | $62.1M | — | +432.6% |
| 4 | ORBIMED ADVISORS#4 · 1,642,891 sh | 1,642,891 | $55.6M | — | +51.2% |
| 5 | RTW INVESTMENTS#5 · 1,637,165 sh | 1,637,165 | $55.5M | — | +11.3% |
| 6 | Foresite Capital Management VI#6 · 1,562,500 sh | 1,562,500 | $52.9M | — | 0.0% |
| 7 | Siren, L.L.C.#7 · 1,375,000 sh | 1,375,000 | $46.6M | — | +136.9% |
| 8 | VANGUARD GROUP#8 · 1,186,791 sh | 1,186,791 | $40.2M | <0.01% | +70.5% |
| 9 | ADAR1 Capital Management#9 · 1,019,358 sh | 1,019,358 | $34.5M | — | +100.8% |
| 10 | Frazier Life Sciences Management, L.P.#10 · 983,333 sh | 983,333 | $33.3M | — | New |
| 11 | BRAIDWELL#11 · 929,694 sh | 929,694 | $31.5M | — | New |
| 12 | Redmile Group#12 · 885,927 sh | 885,927 | $30.0M | — | +60.3% |
| 13 | PERCEPTIVE ADVISORS#13 · 825,890 sh | 825,890 | $28.0M | — | +349.1% |
| 14 | Soleus Capital Management, L.P.#14 · 764,000 sh | 764,000 | $25.9M | — | +42.0% |
| 15 | Nantahala Capital Management#15 · 754,153 sh | 754,153 | $25.5M | — | +21.0% |
| 16 | Ikarian Capital#16 · 665,271 sh | 665,271 | $22.5M | — | +8.2% |
| 17 | Caligan Partners#17 · 644,400 sh | 644,400 | $21.8M | — | New |
| 18 | STATE STREET#18 · 639,804 sh | 639,804 | $21.7M | — | +1611.5% |
| 19 | CITADEL ADVISORS#19 · 591,802 sh | 591,802 | $20.0M | — | +3710.7% |
| 20 | GREAT POINT PARTNERS#20 · 581,187 sh | 581,187 | $19.7M | — | New |
| 21 | Octagon Capital Advisors#21 · 574,000 sh | 574,000 | $19.4M | — | New |
| 22 | BlackRock#22 · 486,153 sh | 486,153 | $16.5M | — | +443.2% |
| 23 | BOONE CAPITAL MANAGEMENT#23 · 470,456 sh | 470,456 | $15.9M | — | -39.9% |
| 24 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#24 · 424,862 sh | 424,862 | $14.4M | — | +836.2% |
| 25 | MPM BioImpact#25 · 397,906 sh | 397,906 | $13.5M | — | New |
| 26 | BOOTHBAY FUND MANAGEMENT#26 · 390,747 sh | 390,747 | $13.2M | — | +74.5% |
| 27 | FMR#27 · 275,758 sh | 275,758 | $9.3M | — | +11.0% |
| 28 | ADAGE CAPITAL PARTNERS GP, L.L.C.#28 · 275,000 sh | 275,000 | $9.3M | — | New |
| 29 | GOLDMAN SACHS GROUP#29 · 254,053 sh | 254,053 | $8.6M | — | +312.6% |
| 30 | Commodore Capital#30 · 250,000 sh | 250,000 | $8.5M | — | New |
| 31 | GEODE CAPITAL MANAGEMENT#31 · 239,790 sh | 239,790 | $8.1M | — | +97.4% |
| 32 | Rock Springs Capital Management#32 · 213,731 sh | 213,731 | $7.2M | — | New |
| 33 | Invesco Ltd.#33 · 167,030 sh | 167,030 | $5.7M | — | +18.8% |
| 34 | AWM Investment Company#34 · 162,560 sh | 162,560 | $5.5M | — | New |
| 35 | Qube Research & Technologies Ltd#35 · 158,292 sh | 158,292 | $5.4M | — | New |
| 36 | Column Group#36 · 156,270 sh | 156,270 | $5.3M | — | -5.9% |
| 37 | TFG Asset Management GP Ltd#37 · 131,770 sh | 131,770 | $4.5M | — | New |
| 38 | Deep Track Capital#38 · 110,448 sh | 110,448 | $3.7M | — | -85.3% |
| 39 | Velan Capital Investment Management#39 · 108,000 sh | 108,000 | $3.7M | — | +35.0% |
| 40 | MILLENNIUM MANAGEMENT#40 · 106,671 sh | 106,671 | $3.6M | — | +171.6% |
| 41 | Atika Capital Management#41 · 94,245 sh | 94,245 | $3.2M | — | New |
| 42 | RENAISSANCE TECHNOLOGIES#42 · 91,173 sh | 91,173 | $3.1M | — | +165.7% |
| 43 | JANE STREET GROUP#43 · 84,778 sh | 84,778 | $2.9M | — | New |
| 44 | MARSHALL WACE, LLP#44 · 84,596 sh | 84,596 | $2.9M | — | +402.2% |
| 45 | Euclidean Capital#45 · 82,234 sh | 82,234 | $2.8M | — | 0.0% |
| 46 | BARCLAYS PLC#46 · 76,659 sh | 76,659 | $2.6M | — | New |
| 47 | UBS Group AG#47 · 66,225 sh | 66,225 | $2.2M | — | +129.9% |
| 48 | Quadrature Capital Ltd#48 · 57,590 sh | 57,590 | $2.0M | — | New |
| 49 | Trexquant Investment#49 · 54,016 sh | 54,016 | $1.8M | — | New |
| 50 | MORGAN STANLEY#50 · 51,324 sh | 51,324 | $1.7M | — | +132.3% |
| 51 | Burkehill Global Management#51 · 50,000 sh | 50,000 | $1.7M | — | New |
| 52 | Connor, Clark & Lunn Investment Management Ltd.#52 · 49,021 sh | 49,021 | $1.7M | — | New |
| 53 | NORTHERN#53 · 40,504 sh | 40,504 | $1.4M | — | +138.0% |
| 54 | Rafferty Asset Management#54 · 32,984 sh | 32,984 | $1.1M | — | New |
| 55 | TWO SIGMA INVESTMENTS#55 · 31,128 sh | 31,128 | $1.1M | — | -10.6% |
| 56 | Point72 Asset Management, L.P.#56 · 25,185 sh | 25,185 | $853.0K | — | +103.5% |
| 57 | Squarepoint Ops#57 · 24,572 sh | 24,572 | $832.3K | — | New |
| 58 | GSA CAPITAL PARTNERS LLP#58 · 22,944 sh | 22,944 | $777.0K | — | +117.3% |
| 59 | LANDSCAPE CAPITAL MANAGEMENT, L.L.C.#59 · 22,859 sh | 22,859 | $774.2K | — | New |
| 60 | Sigma Planning#60 · 19,000 sh | 19,000 | $643.5K | — | New |
| 61 | Man Group plc#61 · 18,802 sh | 18,802 | $636.8K | — | New |
| 62 | TWO SIGMA ADVISERS#62 · 18,448 sh | 18,448 | $624.8K | — | New |
| 63 | XTX Topco Ltd#63 · 18,195 sh | 18,195 | $616.3K | — | New |
| 64 | BANK OF AMERICA#64 · 18,014 sh | 18,014 | $610.1K | — | +353.6% |
| 65 | ACADIAN ASSET MANAGEMENT#65 · 16,788 sh | 16,788 | $568.0K | — | 0.0% |
| 66 | Birchview Capital#66 · 15,000 sh | 15,000 | $508.1K | — | New |
| 67 | BRIDGEWAY CAPITAL MANAGEMENT#67 · 14,375 sh | 14,375 | $486.9K | — | -30.3% |
| 68 | Exome Asset Management#68 · 14,194 sh | 14,194 | $480.8K | — | New |
| 69 | HighTower Advisors#69 · 12,525 sh | 12,525 | $424.2K | — | -0.8% |
| 70 | AJU IB Investment , Ltd.#70 · 12,437 sh | 12,437 | $421.2K | — | 0.0% |
| 71 | PROFUND ADVISORS#71 · 11,892 sh | 11,892 | $402.8K | — | New |
| 72 | OMERS ADMINISTRATION#72 · 11,600 sh | 11,600 | $392.9K | — | New |
| 73 | Y-Intercept (Hong Kong) Ltd#73 · 11,237 sh | 11,237 | $380.6K | — | New |
| 74 | AMERICAN CENTURY COMPANIES#74 · 10,218 sh | 10,218 | $346.1K | — | New |
| 75 | CHARLES SCHWAB INVESTMENT MANAGEMENT#75 · 10,000 sh | 10,000 | $338.7K | — | 0.0% |
| 76 | Jump Financial#76 · 9,845 sh | 9,845 | $333.4K | — | New |
| 77 | Engineers Gate Manager#77 · 9,784 sh | 9,784 | $331.4K | — | New |
| 78 | DIMENSIONAL FUND ADVISORS#78 · 8,934 sh | 8,934 | $302.5K | — | 0.0% |
| 79 | Hudson Bay Capital Management#79 · 8,900 sh | 8,900 | $301.4K | — | New |
| 80 | CANADA PENSION PLAN INVESTMENT BOARD#80 · 8,800 sh | 8,800 | $298.1K | — | New |
| 81 | CITIGROUP#81 · 8,566 sh | 8,566 | $290.1K | — | New |
| 82 | Jain Global#82 · 7,420 sh | 7,420 | $251.3K | — | New |
| 83 | Virtus Investment Advisers#83 · 7,229 sh | 7,229 | $244.8K | — | New |
| 84 | VOLORIDGE INVESTMENT MANAGEMENT#84 · 6,893 sh | 6,893 | $233.5K | — | New |
| 85 | BANK OF NOVA SCOTIA#85 · 6,700 sh | 6,700 | $226.9K | — | New |
| 86 | Opaleye Management#86 · 150,000 sh | 150,000 | $213.4K | — | New |
| 87 | GROUP ONE TRADING, L.P.#87 · 5,282 sh | 5,282 | $178.9K | — | +95.7% |
| 88 | China Universal Asset Management , Ltd.#88 · 4,515 sh | 4,515 | $152.9K | — | New |
| 89 | Tower Research Capital (TRC)#89 · 3,085 sh | 3,085 | $104.5K | — | New |
| 90 | SIMPLEX TRADING#90 · 2,846 sh | 2,846 | $96.4K | — | New |
| 91 | MIRAE ASSET GLOBAL ETFS Ltd.#91 · 1,924 sh | 1,924 | $64.2K | — | New |
| 92 | JPMORGAN CHASE#92 · 1,668 sh | 1,668 | $56.5K | — | +158.2% |
| 93 | Mirae Asset Global Investments , Ltd.#93 · 1,347 sh | 1,347 | $45.6K | — | New |
| 94 | GF FUND MANAGEMENT LTD.#94 · 544 sh | 544 | $18.4K | — | New |
| 95 | BNP PARIBAS FINANCIAL MARKETS#95 · 498 sh | 498 | $16.9K | — | +530.4% |
| 96 | PNC FINANCIAL SERVICES GROUP#96 · 497 sh | 497 | $16.8K | — | 0.0% |
| 97 | Daiwa Securities Group#97 · 92 sh | 92 | $3.0K | — | New |
| 98 | NISA INVESTMENT ADVISORS#98 · 79 sh | 79 | $2.7K | — | 0.0% |
| 99 | Basecamp Wealth Advisors#99 · 68 sh | 68 | $2.3K | — | — |
| 100 | Fortitude Family Office#100 · 63 sh | 63 | $2.1K | — | 0.0% |
Funds that sold out of RAPT in Q4 2025 (9)
Held RAPT at the end of Q3 2025 and filed a Q4 2025 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q3 2025 |
|---|---|---|
| SummitTX Capital, L.P.91,912 sh | 91,912 | $2.4M |
| AMERIPRISE FINANCIAL51,406 sh | 51,406 | $1.3M |
| BALYASNY ASSET MANAGEMENT L.P.50,348 sh | 50,348 | $1.3M |
| SUPERSTRING CAPITAL MANAGEMENT34,449 sh | 34,449 | $888.4K |
| Trustees of Columbia University in the City of New York9,172 sh | 9,172 | $236.5K |
| Russell Investments Group, Ltd.1,080 sh | 1,080 | $27.9K |
| Banque Cantonale Vaudoise154 sh | 154 | $7.0K |
| Wilmington Savings Fund Society, FSB59 sh | 59 | $1.5K |
| SRS Capital Advisors1 sh | 1 | $25.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q4 2025. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q3 2025 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.