Lexeo Therapeutics, Inc. (LXEO) — Institutional Holders, Q2 2026
142 institutional investment managers reported a LXEO position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $410.9M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
LXEO in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- SUVRETTA CAPITAL MANAGEMENTAdded · +5,134,200 sh+$23.9M
- MILLENNIUM MANAGEMENTAdded · +1,220,842 sh+$5.7M
- Qube Research & Technologies LtdAdded · +910,707 sh+$4.2M
- BALYASNY ASSET MANAGEMENT L.P.Added · +823,157 sh+$3.8M
- STATE STREETAdded · +786,515 sh+$3.7M
Biggest sellers
- Paradigm Biocapital AdvisorsTrimmed · -2,008,752 sh-$9.4M
- Point72 Asset Management, L.P.Sold out · -1,680,449 sh-$7.8M
- Octagon Capital AdvisorsSold out · -1,100,000 sh-$5.1M
- Avoro Capital AdvisorsTrimmed · -385,811 sh-$1.8M
- Woodline PartnersTrimmed · -250,000 sh-$1.2M
LXEO 13F holders ranked 1–100 of 142
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | SUVRETTA CAPITAL MANAGEMENT#1 · 6,384,200 sh | 6,384,200 | $29.7M | 0.54% | +410.7% |
| 2 | Affinity Asset Advisors#2 · 5,807,611 sh | 5,807,611 | $27.0M | 1.22% | +15.0% |
| 3 | BlackRock#3 · 5,739,455 sh | 5,739,455 | $26.7M | <0.01% | +12.3% |
| 4 | RA CAPITAL MANAGEMENT, L.P.#4 · 5,000,000 sh | 5,000,000 | $23.3M | 0.20% | 0.0% |
| 5 | Frazier Life Sciences Management, L.P.#5 · 4,824,725 sh | 4,824,725 | $22.5M | 0.49% | +9.0% |
| 6 | STATE STREET#6 · 4,354,757 sh | 4,354,757 | $20.3M | <0.01% | +22.0% |
| 7 | Vestal Point Capital#7 · 4,320,000 sh | 4,320,000 | $20.1M | 0.47% | -3.5% |
| 8 | Paradigm Biocapital Advisors#8 · 4,175,382 sh | 4,175,382 | $19.4M | 0.36% | -32.5% |
| 9 | Jupiter Topco#9 · 3,954,691 sh | 3,954,691 | $18.4M | <0.01% | — |
| 10 | ORBIMED ADVISORS#10 · 3,947,850 sh | 3,947,850 | $18.4M | 0.34% | +9.6% |
| 11 | CITADEL ADVISORS#11 · 3,898,570 sh | 3,898,570 | $18.1M | <0.01% | +1.7% |
| 12 | VANGUARD CAPITAL MANAGEMENT#12 · 3,125,893 sh | 3,125,893 | $14.6M | <0.01% | +4.0% |
| 13 | MILLENNIUM MANAGEMENT#13 · 2,833,622 sh | 2,833,622 | $13.2M | <0.01% | +75.7% |
| 14 | Woodline Partners#14 · 2,500,532 sh | 2,500,532 | $11.6M | 0.04% | -9.1% |
| 15 | BALYASNY ASSET MANAGEMENT L.P.#15 · 2,412,742 sh | 2,412,742 | $11.2M | 0.01% | +51.8% |
| 16 | GOLDMAN SACHS GROUP#16 · 2,149,612 sh | 2,149,612 | $10.0M | <0.01% | +10.2% |
| 17 | 683 Capital Management#17 · 1,875,000 sh | 1,875,000 | $8.7M | 0.43% | +56.2% |
| 18 | GEODE CAPITAL MANAGEMENT#18 · 1,747,959 sh | 1,747,959 | $8.1M | <0.01% | +15.5% |
| 19 | ADAR1 Capital Management#19 · 1,565,950 sh | 1,565,950 | $7.3M | 0.33% | +6.7% |
| 20 | Avoro Capital Advisors#20 · 1,489,189 sh | 1,489,189 | $6.9M | 0.06% | -20.6% |
| 21 | Qube Research & Technologies Ltd#21 · 1,376,222 sh | 1,376,222 | $6.4M | <0.01% | +195.6% |
| 22 | Nantahala Capital Management#22 · 1,300,000 sh | 1,300,000 | $6.1M | 0.20% | +8.3% |
| 23 | DIMENSIONAL FUND ADVISORS#23 · 1,287,185 sh | 1,287,185 | $6.0M | <0.01% | +16.6% |
| 24 | Spruce Street Capital#24 · 928,593 sh | 928,593 | $4.3M | 0.85% | 0.0% |
| 25 | Blackstone#25 · 904,959 sh | 904,959 | $4.2M | 0.01% | 0.0% |
| 26 | NORTHERN#26 · 867,391 sh | 867,391 | $4.0M | <0.01% | +75.7% |
| 27 | abrdn plc#27 · 675,092 sh | 675,092 | $3.1M | <0.01% | +174.5% |
| 28 | VANGUARD PORTFOLIO MANAGEMENT#28 · 613,826 sh | 613,826 | $2.9M | <0.01% | +6.3% |
| 29 | Ikarian Capital#29 · 513,011 sh | 513,011 | $2.4M | 0.26% | 0.0% |
| 30 | BANK OF AMERICA#30 · 490,331 sh | 490,331 | $2.3M | <0.01% | -0.2% |
| 31 | VANGUARD FIDUCIARY#31 · 430,696 sh | 430,696 | $2.0M | <0.01% | +11.9% |
| 32 | MORGAN STANLEY#32 · 395,102 sh | 395,102 | $1.8M | <0.01% | -1.9% |
| 33 | BNP PARIBAS FINANCIAL MARKETS#33 · 388,398 sh | 388,398 | $1.8M | <0.01% | +70.2% |
| 34 | DAFNA Capital Management#34 · 377,059 sh | 377,059 | $1.8M | 0.33% | 0.0% |
| 35 | UBS Group AG#35 · 354,044 sh | 354,044 | $1.6M | <0.01% | +10.0% |
| 36 | Trexquant Investment#36 · 314,891 sh | 314,891 | $1.5M | <0.01% | New |
| 37 | Squarepoint Ops#37 · 294,774 sh | 294,774 | $1.4M | <0.01% | -7.6% |
| 38 | Hennion & Walsh Asset Management#38 · 265,697 sh | 265,697 | $1.2M | — | New |
| 39 | AQR CAPITAL MANAGEMENT#39 · 256,661 sh | 256,661 | $1.2M | <0.01% | -24.4% |
| 40 | RENAISSANCE TECHNOLOGIES#40 · 250,365 sh | 250,365 | $1.2M | <0.01% | New |
| 41 | WELLINGTON MANAGEMENT GROUP LLP#41 · 202,383 sh | 202,383 | $942.1K | <0.01% | +17.2% |
| 42 | Nuveen#42 · 200,417 sh | 200,417 | $932.9K | <0.01% | +9.5% |
| 43 | Bank of New York Mellon#43 · 183,883 sh | 183,883 | $856.0K | <0.01% | +15.7% |
| 44 | CHARLES SCHWAB INVESTMENT MANAGEMENT#44 · 172,609 sh | 172,609 | $803.5K | <0.01% | -5.2% |
| 45 | Susquehanna Portfolio Strategies#45 · 161,062 sh | 161,062 | $749.7K | 0.01% | +42.6% |
| 46 | Privium Fund Management B.V.#46 · 155,000 sh | 155,000 | $722.3K | 0.13% | -24.4% |
| 47 | XTX Topco Ltd#47 · 145,556 sh | 145,556 | $677.6K | <0.01% | +44.7% |
| 48 | FMR#48 · 141,146 sh | 141,146 | $657.0K | 0.00% | +478.8% |
| 49 | BOOTHBAY FUND MANAGEMENT#49 · 136,377 sh | 136,377 | $634.8K | <0.01% | 0.0% |
| 50 | Burkehill Global Management#50 · 125,000 sh | 125,000 | $581.9K | 0.02% | 0.0% |
| 51 | RAYMOND JAMES FINANCIAL#51 · 117,388 sh | 117,388 | $546.4K | <0.01% | +653.2% |
| 52 | Palumbo Wealth Management#52 · 114,743 sh | 114,743 | $534.1K | 0.11% | New |
| 53 | Fisher Asset Management#53 · 114,322 sh | 114,322 | $532.2K | <0.01% | New |
| 54 | EntryPoint Capital#54 · 103,648 sh | 103,648 | $482.5K | 0.12% | +525.9% |
| 55 | JPMORGAN CHASE#55 · 96,290 sh | 96,290 | $463.2K | 0.00% | +3.4% |
| 56 | ALLIANCEBERNSTEIN L.P.#56 · 77,860 sh | 77,860 | $446.9K | <0.01% | +26.0% |
| 57 | CITIGROUP#57 · 93,743 sh | 93,743 | $436.4K | <0.01% | +603.8% |
| 58 | DEUTSCHE BANK AG\#58 · 82,293 sh | 82,293 | $383.5K | <0.01% | +30.5% |
| 59 | RHUMBLINE ADVISERS#59 · 79,809 sh | 79,809 | $371.5K | <0.01% | +10.7% |
| 60 | Invesco Ltd.#60 · 76,219 sh | 76,219 | $354.8K | 0.00% | +20.0% |
| 61 | Virtus Investment Advisers#61 · 74,874 sh | 74,874 | $348.5K | 0.08% | +168.3% |
| 62 | Walleye Capital#62 · 73,868 sh | 73,868 | $343.9K | <0.01% | New |
| 63 | Creative Planning#63 · 72,625 sh | 72,625 | $338.1K | <0.01% | +8.3% |
| 64 | Rafferty Asset Management#64 · 67,535 sh | 67,535 | $314.4K | <0.01% | -33.1% |
| 65 | WELLS FARGO & COMPANY#65 · 59,365 sh | 59,365 | $276.3K | 0.00% | +137.5% |
| 66 | PRICE T ROWE ASSOCIATES#66 · 58,194 sh | 58,194 | $271.0K | 0.00% | +34.9% |
| 67 | Mitsubishi UFJ Asset Management , Ltd.#67 · 49,988 sh | 49,988 | $232.7K | <0.01% | +95.4% |
| 68 | STATE OF WISCONSIN INVESTMENT BOARD#68 · 48,324 sh | 48,324 | $224.9K | <0.01% | New |
| 69 | LOS ANGELES CAPITAL MANAGEMENT#69 · 48,176 sh | 48,176 | $224.3K | <0.01% | +30.0% |
| 70 | MIRAE ASSET GLOBAL ETFS Ltd.#70 · 40,485 sh | 40,485 | $189.7K | <0.01% | +9.2% |
| 71 | MetLife Investment Management#71 · 39,548 sh | 39,548 | $184.1K | <0.01% | +11.1% |
| 72 | PROFUND ADVISORS#72 · 34,317 sh | 34,317 | $159.7K | <0.01% | -24.0% |
| 73 | Russell Investments Group, Ltd.#73 · 33,273 sh | 33,273 | $154.9K | <0.01% | +401.2% |
| 74 | Dynamic Technology Lab Private Ltd#74 · 32,651 sh | 32,651 | $152.0K | 0.03% | New |
| 75 | Verdad Advisers#75 · 30,591 sh | 30,591 | $142.4K | 0.14% | New |
| 76 | ExodusPoint Capital Management#76 · 27,880 sh | 27,880 | $129.8K | <0.01% | -75.1% |
| 77 | Police & Firemen's Retirement System of New Jersey#77 · 25,535 sh | 25,535 | $118.9K | <0.01% | +56.0% |
| 78 | Quantinno Capital Management#78 · 24,293 sh | 24,293 | $113.1K | <0.01% | New |
| 79 | Vanguard Global Advisers#79 · 23,385 sh | 23,385 | $108.9K | <0.01% | -45.1% |
| 80 | PRELUDE CAPITAL MANAGEMENT#80 · 22,500 sh | 22,500 | $104.7K | <0.01% | New |
| 81 | Soltis Investment Advisors#81 · 20,016 sh | 20,016 | $93.2K | <0.01% | +0.1% |
| 82 | NEW YORK STATE COMMON RETIREMENT FUND#82 · 19,887 sh | 19,887 | $92.6K | <0.01% | 0.0% |
| 83 | D. E. Shaw#83 · 19,866 sh | 19,866 | $92.5K | 0.00% | -34.8% |
| 84 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#84 · 19,805 sh | 19,805 | $92.2K | <0.01% | +11.7% |
| 85 | Vanguard Personalized Indexing Management#85 · 19,466 sh | 19,466 | $90.6K | <0.01% | +10.8% |
| 86 | AMERICAN CENTURY COMPANIES#86 · 18,855 sh | 18,855 | $87.8K | 0.00% | New |
| 87 | CANADA PENSION PLAN INVESTMENT BOARD#87 · 18,500 sh | 18,500 | $86.1K | 0.00% | New |
| 88 | INTECH INVESTMENT MANAGEMENT#88 · 17,817 sh | 17,817 | $82.9K | <0.01% | +8.0% |
| 89 | CAXTON#89 · 16,962 sh | 16,962 | $79.0K | 4.26% | +21.7% |
| 90 | Jain Global#90 · 16,585 sh | 16,585 | $77.2K | <0.01% | New |
| 91 | BARCLAYS PLC#91 · 16,257 sh | 16,257 | $75.7K | 0.00% | +33.6% |
| 92 | Spark Investment Management#92 · 15,000 sh | 15,000 | $69.8K | 0.14% | New |
| 93 | VOYA INVESTMENT MANAGEMENT#93 · 14,230 sh | 14,230 | $66.2K | <0.01% | +32.9% |
| 94 | Cerity Partners#94 · 13,911 sh | 13,911 | $64.8K | <0.01% | -33.8% |
| 95 | WEALTH ENHANCEMENT ADVISORY SERVICES#95 · 12,745 sh | 12,745 | $61.4K | — | -20.3% |
| 96 | China Universal Asset Management , Ltd.#96 · 12,497 sh | 12,497 | $58.2K | <0.01% | -3.5% |
| 97 | ProShare Advisors#97 · 11,853 sh | 11,853 | $55.2K | <0.01% | -7.8% |
| 98 | PRUDENTIAL FINANCIAL#98 · 11,585 sh | 11,585 | $53.9K | <0.01% | New |
| 99 | COMMONWEALTH EQUITY SERVICES#99 · 11,123 sh | 11,123 | $51.8K | <0.01% | -18.3% |
| 100 | SG Americas Securities#100 · 10,555 sh | 10,555 | $49.0K | 0.00% | New |
Funds that sold out of LXEO in Q2 2026 (22)
Held LXEO at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Point72 Asset Management, L.P.1,680,449 sh | 1,680,449 | $9.6M |
| Octagon Capital Advisors1,100,000 sh | 1,100,000 | $6.3M |
| TWO SIGMA INVESTMENTS181,676 sh | 181,676 | $1.0M |
| Y-Intercept (Hong Kong) Ltd142,571 sh | 142,571 | $818.4K |
| DRW Securities47,988 sh | 47,988 | $275.5K |
| Bleakley Financial Group47,964 sh | 47,964 | $275.3K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP46,998 sh | 46,998 | $269.8K |
| GSA CAPITAL PARTNERS LLP34,269 sh | 34,269 | $197.0K |
| PANAGORA ASSET MANAGEMENT34,297 sh | 34,297 | $196.9K |
| AXQ CAPITAL26,119 sh | 26,119 | $149.9K |
| Schonfeld Strategic Advisors24,221 sh | 24,221 | $139.0K |
| BRIDGEWAY CAPITAL MANAGEMENT13,400 sh | 13,400 | $76.9K |
| E Fund Management , Ltd.12,683 sh | 12,683 | $72.8K |
| Virtu Financial11,901 sh | 11,901 | $68.0K |
| Ethic11,132 sh | 11,132 | $63.9K |
| Larson Financial Group1,456 sh | 1,456 | $8.4K |
| SIMPLEX TRADING1,240 sh | 1,240 | $7.1K |
| OSAIC411 sh | 411 | $2.4K |
| Bare Financial Services80 sh | 80 | $459.00 |
| Caitong International Asset Management , Ltd60 sh | 60 | $344.00 |
| Basecamp Wealth Advisors29 sh | 29 | $166.00 |
| MAI Capital Management11 sh | 11 | $64.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.