ARROWHEAD PHARMACEUTICALS, INC. (ARWR) — Institutional Holders, Q2 2026

503 institutional investment managers reported a ARWR position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $9.7B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← ARWR stock profile

ARWR in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

124

Added to

155

Trimmed

153

Sold out

Biggest buyers

FIRST ADVISORSAdded · +1,203,770 sh+$98.1M
Holocene AdvisorsNew · +1,106,177 sh+$90.2M
FMRAdded · +773,152 sh+$63.0M
Avoro Capital AdvisorsAdded · +655,556 sh+$53.4M
Invesco Ltd.Added · +603,329 sh+$49.2M

Biggest sellers

BlackRockTrimmed · -3,330,966 sh-$271.5M
STATE STREETTrimmed · -801,490 sh-$65.3M
VANGUARD PORTFOLIO MANAGEMENTTrimmed · -794,781 sh-$64.8M
D. E. ShawTrimmed · -752,278 sh-$61.3M
GEODE CAPITAL MANAGEMENTTrimmed · -748,216 sh-$61.0M

ARWR 13F holders ranked 1–100 of 503

Institutional investors reporting a position in ARROWHEAD PHARMACEUTICALS, INC. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q1 2026
1	BlackRock#1 · 14,830,553 sh	14,830,553	$1.2B	0.02%	-18.3%
2	Avoro Capital Advisors#2 · 11,355,555 sh	11,355,555	$925.6M	8.31%	+6.1%
3	FMR#3 · 8,039,804 sh	8,039,804	$655.3M	0.03%	+10.6%
4	VANGUARD PORTFOLIO MANAGEMENT#4 · 6,351,355 sh	6,351,355	$517.7M	0.02%	-11.1%
5	VANGUARD CAPITAL MANAGEMENT#5 · 6,110,953 sh	6,110,953	$498.1M	0.01%	+1.3%
6	STATE STREET#6 · 5,694,640 sh	5,694,640	$464.2M	0.01%	-12.3%
7	NORGES BANK#7 · 3,896,536 sh	3,896,536	$317.6M	0.03%	—
8	Invesco Ltd.#8 · 3,883,976 sh	3,883,976	$316.6M	0.03%	+18.4%
9	GEODE CAPITAL MANAGEMENT#9 · 3,530,612 sh	3,530,612	$298.8M	0.02%	-17.5%
10	FRED ALGER MANAGEMENT#10 · 3,301,919 sh	3,301,919	$269.1M	0.90%	-1.2%
11	BAKER BROS. ADVISORS#11 · 1,992,783 sh	1,992,783	$162.4M	0.81%	0.0%
12	Siren, L.L.C.#12 · 1,715,476 sh	1,715,476	$139.8M	2.83%	+6.2%
13	Vestal Point Capital#13 · 1,575,000 sh	1,575,000	$128.4M	3.00%	-30.8%
14	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)#14 · 1,389,055 sh	1,389,055	$113.2M	1.18%	-11.7%
15	FIRST ADVISORS#15 · 1,352,918 sh	1,352,918	$110.3M	0.06%	+807.1%
16	DRIEHAUS CAPITAL MANAGEMENT#16 · 1,350,556 sh	1,350,556	$110.1M	0.64%	+13.5%
17	Jupiter Topco#17 · 1,221,596 sh	1,221,596	$99.6M	0.04%	—
18	NORTHERN#18 · 1,192,868 sh	1,192,868	$97.2M	0.01%	-28.0%
19	DIMENSIONAL FUND ADVISORS#19 · 1,181,608 sh	1,181,608	$96.3M	0.02%	+94.2%
20	GOLDMAN SACHS GROUP#20 · 1,150,007 sh	1,150,007	$93.7M	<0.01%	-33.9%
21	BANK OF AMERICA#21 · 1,139,810 sh	1,139,810	$92.9M	<0.01%	+7.1%
22	Hood River Capital Management#22 · 1,120,747 sh	1,120,747	$91.4M	0.66%	+6.1%
23	Holocene Advisors#23 · 1,106,177 sh	1,106,177	$90.2M	0.20%	New
24	MORGAN STANLEY#24 · 1,084,835 sh	1,084,835	$88.4M	<0.01%	+12.9%
25	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#25 · 964,479 sh	964,479	$78.6M	0.01%	-27.5%
26	Fisher Asset Management#26 · 957,691 sh	957,691	$78.1M	0.02%	-14.0%
27	CHARLES SCHWAB INVESTMENT MANAGEMENT#27 · 923,927 sh	923,927	$75.3M	0.01%	-22.5%
28	VANGUARD FIDUCIARY#28 · 896,738 sh	896,738	$73.1M	0.02%	-7.1%
29	UBS Group AG#29 · 861,520 sh	861,520	$70.2M	<0.01%	-35.5%
30	Bank of New York Mellon#30 · 859,538 sh	859,538	$70.1M	0.01%	-10.5%
31	PRICE T ROWE ASSOCIATES#31 · 853,360 sh	853,360	$69.6M	<0.01%	-18.2%
32	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT#32 · 830,247 sh	830,247	$67.7M	1.19%	+53.7%
33	Western Financial#33 · 820,239 sh	820,239	$66.9M	—	0.0%
34	JPMORGAN CHASE#34 · 637,399 sh	637,399	$51.8M	<0.01%	-6.7%
35	Connor, Clark & Lunn Investment Management Ltd.#35 · 625,569 sh	625,569	$51.0M	0.10%	-25.3%
36	SUSQUEHANNA INTERNATIONAL GROUP, LLP#36 · 596,573 sh	596,573	$48.6M	<0.01%	+57.5%
37	TWO SIGMA INVESTMENTS#37 · 580,609 sh	580,609	$47.3M	0.03%	+1521.8%
38	Pictet Asset Management Holding SA#38 · 573,419 sh	573,419	$46.7M	0.04%	-55.0%
39	BNP PARIBAS FINANCIAL MARKETS#39 · 558,643 sh	558,643	$45.5M	0.02%	-14.1%
40	LORD, ABBETT#40 · 540,466 sh	540,466	$44.1M	0.13%	+72.8%
41	1832 Asset Management L.P.#41 · 538,500 sh	538,500	$43.9M	0.02%	New
42	PRINCIPAL FINANCIAL GROUP#42 · 514,658 sh	514,658	$41.9M	0.02%	+5.0%
43	HRT FINANCIAL#43 · 498,655 sh	498,655	$40.6M	0.10%	New
44	VOYA INVESTMENT MANAGEMENT#44 · 483,495 sh	483,495	$39.4M	0.03%	-26.3%
45	BALYASNY ASSET MANAGEMENT L.P.#45 · 470,754 sh	470,754	$38.4M	0.05%	+128.1%
46	RENAISSANCE TECHNOLOGIES#46 · 468,921 sh	468,921	$38.2M	0.05%	-54.8%
47	FRANKLIN RESOURCES#47 · 462,133 sh	462,133	$37.7M	<0.01%	-0.1%
48	D. E. Shaw#48 · 431,560 sh	431,560	$35.2M	0.02%	-63.5%
49	Nuveen#49 · 415,883 sh	415,883	$33.9M	<0.01%	-16.8%
50	RHUMBLINE ADVISERS#50 · 374,897 sh	374,897	$30.6M	0.02%	-7.3%
51	EVENTIDE ASSET MANAGEMENT#51 · 370,000 sh	370,000	$30.2M	0.40%	0.0%
52	AMERICAN CENTURY COMPANIES#52 · 364,211 sh	364,211	$29.7M	0.01%	-44.1%
53	MILLENNIUM MANAGEMENT#53 · 329,337 sh	329,337	$26.8M	<0.01%	New
54	LPL Financial#54 · 310,761 sh	310,761	$25.3M	<0.01%	+140.0%
55	Artisan Partners Limited Partnership#55 · 310,706 sh	310,706	$25.3M	0.04%	New
56	MARSHALL WACE, LLP#56 · 305,031 sh	305,031	$24.9M	0.02%	+69.9%
57	SEI INVESTMENTS#57 · 300,619 sh	300,619	$24.5M	0.02%	+47.9%
58	NORDEA INVESTMENT MANAGEMENT AB#58 · 284,175 sh	284,175	$23.6M	0.02%	-7.3%
59	Russell Investments Group, Ltd.#59 · 284,096 sh	284,096	$23.2M	0.02%	+63.3%
60	CITIGROUP#60 · 264,678 sh	264,678	$21.6M	<0.01%	+5.2%
61	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM#61 · 256,314 sh	256,314	$20.9M	0.01%	-0.3%
62	Squarepoint Ops#62 · 255,907 sh	255,907	$20.9M	0.02%	New
63	ENVESTNET ASSET MANAGEMENT#63 · 254,228 sh	254,228	$20.7M	<0.01%	+280.9%
64	abrdn plc#64 · 251,968 sh	251,968	$20.5M	0.03%	-30.8%
65	Swiss National Bank#65 · 238,900 sh	238,900	$19.5M	0.01%	-1.3%
66	Legal & General Group Plc#66 · 237,216 sh	237,216	$19.3M	<0.01%	+3.5%
67	Privium Fund Management B.V.#67 · 234,222 sh	234,222	$19.1M	3.51%	-36.2%
68	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP#68 · 218,133 sh	218,133	$17.8M	<0.01%	-62.8%
69	Life Cycle Investment Partners Ltd#69 · 209,068 sh	209,068	$17.0M	0.08%	New
70	HSBC PLC#70 · 203,800 sh	203,800	$16.8M	<0.01%	+34.9%
71	Assenagon Asset Management S.A.#71 · 201,927 sh	201,927	$16.5M	—	+243.8%
72	Woodline Partners#72 · 200,184 sh	200,184	$16.3M	0.05%	0.0%
73	Integral Health Asset Management#73 · 200,000 sh	200,000	$16.3M	0.64%	-33.3%
74	JANE STREET GROUP#74 · 196,205 sh	196,205	$16.0M	<0.01%	+1143.8%
75	AQR CAPITAL MANAGEMENT#75 · 198,842 sh	198,842	$15.8M	<0.01%	+18.9%
76	MUTUAL OF AMERICA CAPITAL MANAGEMENT#76 · 191,432 sh	191,432	$15.6M	—	+3.9%
77	PINNACLE ASSOCIATES LTD#77 · 170,131 sh	170,131	$13.9M	—	-3.0%
78	RAYMOND JAMES FINANCIAL#78 · 169,913 sh	169,913	$13.8M	<0.01%	-6.9%
79	WCM INVESTMENT MANAGEMENT#79 · 171,232 sh	171,232	$13.8M	0.03%	-0.2%
80	SEB Asset Management AB#80 · 158,205 sh	158,205	$12.9M	0.05%	0.0%
81	Clearbridge Investments#81 · 157,110 sh	157,110	$12.8M	0.01%	-22.4%
82	AMERIPRISE FINANCIAL#82 · 155,908 sh	155,908	$12.7M	<0.01%	-18.4%
83	Affinity Asset Advisors#83 · 150,000 sh	150,000	$12.2M	0.55%	-25.0%
84	DEUTSCHE BANK AG\#84 · 149,240 sh	149,240	$12.2M	<0.01%	-42.6%
85	WEALTH EFFECTS#85 · 147,300 sh	147,300	$12.0M	—	+2.8%
86	Retirement Systems of Alabama#86 · 145,687 sh	145,687	$11.9M	0.04%	-15.1%
87	TORONTO DOMINION BANK#87 · 144,928 sh	144,928	$11.8M	0.01%	-3.6%
88	HighTower Advisors#88 · 140,394 sh	140,394	$11.4M	0.01%	-4.1%
89	Weiss Asset Management#89 · 134,014 sh	134,014	$10.9M	0.11%	New
90	BANK OF NOVA SCOTIA#90 · 133,805 sh	133,805	$10.9M	0.02%	-1.6%
91	ALLIANCEBERNSTEIN L.P.#91 · 173,265 sh	173,265	$10.9M	<0.01%	-38.2%
92	PFM Health Sciences#92 · 131,667 sh	131,667	$10.7M	0.92%	+104.8%
93	TFG Asset Management GP Ltd#93 · 130,484 sh	130,484	$10.6M	1.67%	+2.6%
94	WELLS FARGO & COMPANY#94 · 128,789 sh	128,789	$10.5M	<0.01%	-18.7%
95	Rhenman & Partners Asset Management AB#95 · 128,000 sh	128,000	$10.4M	0.98%	-11.4%
96	VANGUARD ASSET MANAGEMENT, Ltd#96 · 119,102 sh	119,102	$9.7M	<0.01%	+5.4%
97	Catalyst Funds Management Pty Ltd#97 · 117,600 sh	117,600	$9.6M	0.54%	New
98	NEW YORK STATE TEACHERS RETIREMENT SYSTEM#98 · 116,948 sh	116,948	$9.5M	—	-6.3%
99	Universal- Beteiligungs- und Servicegesellschaft mbH#99 · 116,393 sh	116,393	$9.5M	0.01%	-3.2%
100	MANUFACTURERS LIFE INSURANCE COMPANY, THE#100 · 111,955 sh	111,955	$9.1M	<0.01%	-30.2%

Funds that sold out of ARWR in Q2 2026 (57)

Held ARWR at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held ARWR in Q1 2026 and reported no position in Q2 2026.
Institution	Shares sold	Value in Q1 2026
RTW INVESTMENTS585,682 sh	585,682	$36.7M
CANADA PENSION PLAN INVESTMENT BOARD325,700 sh	325,700	$20.4M
Longaeva Partners L.P.194,589 sh	194,589	$12.2M
SCHRODER INVESTMENT MANAGEMENT GROUP162,005 sh	162,005	$9.3M
CITADEL ADVISORS98,194 sh	98,194	$6.2M
Bridgewater Associates95,552 sh	95,552	$6.0M
Aquatic Capital Management80,227 sh	80,227	$5.0M
PDT Partners70,048 sh	70,048	$4.4M
Quadrature Capital Ltd55,546 sh	55,546	$3.5M
Ishara Investments55,350 sh	55,350	$3.5M
Cinctive Capital Management49,068 sh	49,068	$3.1M
J. Goldman41,210 sh	41,210	$2.6M
INTECH INVESTMENT MANAGEMENT35,848 sh	35,848	$2.2M
Diversified34,553 sh	34,553	$2.2M
SECTOR GAMMA AS30,000 sh	30,000	$1.9M
Soleus Capital Management, L.P.28,479 sh	28,479	$1.8M
FORA Capital23,625 sh	23,625	$1.5M
Campbell & Investment Adviser18,936 sh	18,936	$1.2M
FARALLON CAPITAL MANAGEMENT15,800 sh	15,800	$990.7K
Capstone Capital Management Ltd15,740 sh	15,740	$986.9K
PRELUDE CAPITAL MANAGEMENT15,217 sh	15,217	$954.1K
SIERRA SUMMIT ADVISORS14,353 sh	14,353	$899.9K
Havemeyer Place13,276 sh	13,276	$832.4K
Elo Mutual Pension Insurance12,208 sh	12,208	$765.4K
Ares Systematic Credit Ltd13,169 sh	13,169	$759.2K
Fieldview Capital Management11,555 sh	11,555	$724.5K
Cypress Point Wealth Management11,200 sh	11,200	$702.2K
Entropy Technologies10,620 sh	10,620	$665.9K
Three Seasons Wealth9,315 sh	9,315	$584.1K
GSA CAPITAL PARTNERS LLP8,865 sh	8,865	$556.0K
SEVEN GRAND MANAGERS7,500 sh	7,500	$470.3K
AVIVA PLC7,294 sh	7,294	$457.3K
EntryPoint Capital7,248 sh	7,248	$454.4K
Quarry6,750 sh	6,750	$423.2K
Velan Capital Investment Management6,500 sh	6,500	$407.6K
Integrated Quantitative Investments5,842 sh	5,842	$366.3K
Janney Montgomery Scott4,296 sh	4,296	$269.0K
MANGROVE PARTNERS IM3,797 sh	3,797	$238.1K
INTERNATIONAL ASSETS INVESTMENT MANAGEMENT3,413 sh	3,413	$214.7K
Alvarez & Marsal Private Wealth Partners3,215 sh	3,215	$201.6K
Kemnay Advisory Services998 sh	998	$62.6K
Optiver Holding B.V.408 sh	408	$25.6K
Sound Income Strategies393 sh	393	$24.7K
Lloyd Advisory Services311 sh	311	$19.5K
Kingdom Financial Group311 sh	311	$19.5K
TWIN PEAKS WEALTH ADVISORS168 sh	168	$10.5K
Quest 10 Wealth Builders104 sh	104	$6.5K
Matrix100 sh	100	$6.0K
Tradewinds Capital Management90 sh	90	$5.6K
Annis Gardner Whiting Capital Advisors80 sh	80	$5.0K
Strategic Wealth Partners, Ltd.70 sh	70	$4.4K
Networth Advisors51 sh	51	$3.2K
Key Capital Management40 sh	40	$2.5K
Kilter Group32 sh	32	$2.0K
Basecamp Wealth Advisors29 sh	29	$1.8K
Innovative Asset Advisors Group19 sh	19	$1.2K
Elequin Securities59 sh	59	—

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.