What hedge funds are most similar to RA CAPITAL MANAGEMENT, L.P.?

The funds with the most similar 13F portfolios to RA CAPITAL MANAGEMENT, L.P. are Siren, L.L.C., Cormorant Asset, PERCEPTIVE ADVISORS, based on overlapping conviction holdings in the latest SEC filings.

How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to RA

13F Portfolio OverlapQ2 2026RA portfolio →

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Most similar hedge funds by 13F overlap

RA CAPITAL MANAGEMENT, L.P. is an institutional investor managing $11.5B across 84 U.S. equity positions as of Q2 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to RA are Siren, L.L.C., Cormorant Asset, PERCEPTIVE ADVISORS, with shared positions in $EWTX, $RYTM, $BCAX, $PBLS, $ABVX, $COAG. The full ranking of 25 similar funds is below.

#1Siren, L.L.C.Active

Notable overlap · 11 shared positions

$EWTX $RYTM $BCAX $PBLS $ABVX $COAG

$4.9B

117 positions

#2Cormorant Asset Management, LPActive

Notable overlap · 8 shared positions

$PBLS $EWTX $ABVX $ORKA $CLYM $NAMS

$2.0B

50 positions

#3PERCEPTIVE ADVISORS LLCActive

Notable overlap · 7 shared positions

$RYTM $EWTX $NUVL $ORKA $BCRX $SLDB

$6.7B

109 positions

#4Deep Track Capital, LPActive

Notable overlap · 9 shared positions

$PCVX $COAG $BCAX $NUVL $ORKA $GHRS

$6.9B

67 positions

#5NEXTBio Capital Management LPActive

Notable overlap · 6 shared positions

$RYTM $PCVX $IRON $ZLAB $LBRX $EVMN

$217M

22 positions

#6Catalio Capital Management, LPActive

Notable overlap · 6 shared positions

$PBLS $SEPN $MLYS $IRON $DFTX $FDMT

$532M

39 positions

#7StemPoint Capital LPActive

Notable overlap · 7 shared positions

$TYRA $MLYS $ABVX $ORKA $CLYM $DFTX

$581M

84 positions

#8TCG Crossover Management, LLCActive

Notable overlap · 8 shared positions

$TYRA $IRON $BCRX $ABVX $ZLAB $XNCR

$4.2B

54 positions

#9Paradigm Biocapital Advisors LPActive

Notable overlap · 6 shared positions

$EWTX $PCVX $NUVL $ORKA $TYRA $JBIO

$5.3B

28 positions

#10Saturn V Capital Management LPActive

Notable overlap · 4 shared positions

$PCVX $IRON $ABVX $MNPR

$697M

23 positions

#11First Turn Management, LLCActive

Notable overlap · 7 shared positions

$PCVX $NAMS $RYTM $ABVX $ORKA $SION

$935M

31 positions

#12Kalehua Capital Management LLCActive

Notable overlap · 5 shared positions

$SION $SEPN $TYRA $ACRS $DMRA

$140M

23 positions

#13SILVERARC CAPITAL MANAGEMENT, LLCActive

Notable overlap · 7 shared positions

$RYTM $ABVX $ORKA $PCVX $DFTX $ACRS

$962M

73 positions

#14Novo Holdings A/SActive

Notable overlap · 4 shared positions

$EWTX $COAG $PCVX $FDMT

$1.7B

25 positions

#15Samsara BioCapital, LLCSmart money

Notable overlap · 7 shared positions

$SEPN $MLYS $SGP $PBLS $JBIO $ARTV

$1.2B

24 positions

#16Caligan Partners LPSmart money

Notable overlap · 5 shared positions

$PCVX $ABVX $TYRA $LBRX $ARTV

$2.1B

28 positions

#17Ishara Investments LPActive

Notable overlap · 7 shared positions

$PCVX $MLYS $WVE $SION $NAMS $SPRY

$136M

41 positions

#18Vestal Point Capital, LPActive

Notable overlap · 5 shared positions

$BCAX $IRON $TSHA $BCRX $ABVX

$4.3B

68 positions

#19Kynam Capital Management, LPActive

Notable overlap · 4 shared positions

$PCVX $BCRX $GERN $PBLS

$1.8B

32 positions

#20ORBIMED ADVISORS LLCActive

Notable overlap · 5 shared positions

$EWTX $SION $ABVX $MLYS $SPRY

$5.4B

129 positions

#21HighVista Strategies LLCPassive

Notable overlap · 8 shared positions

$PCVX $ABVX $TYRA $GHRS $ORKA $EWTX

$439M

147 positions

#22Frazier Life Sciences Management, L.P.Smart money

Notable overlap · 6 shared positions

$NAMS $IRON $PBLS $BCRX $ZLAB $ACRS

$4.6B

41 positions

#23Bain Capital Life Sciences Investors, LLCSmart money

Notable overlap · 4 shared positions

$NAMS $COAG $SLDB $IRON

$1.7B

21 positions

#24KVP Capital Advisors, LPActive

Notable overlap · 4 shared positions

$EWTX $IRON $MLYS $ARTV

$136M

35 positions

#25Elmind Capital, LPActive

Notable overlap · 5 shared positions

$PCVX $BCRX $SEPN $WVE $TYRA

$398M

35 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.