How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to Paradigm Biocapital Advisors

13F Portfolio OverlapQ2 2026Paradigm Biocapital Advisors portfolio →

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Most similar hedge funds by 13F overlap

Paradigm Biocapital Advisors LP is an institutional investor managing $5.3B across 28 U.S. equity positions as of Q2 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to Paradigm Biocapital Advisors are Caligan Partners, Darwin Global , Ltd., DEERFIELD COMPANY, (SERIES C), with shared positions in $RVMD, $TNGX, $PCVX, $VRDN, $TYRA, $VOR. The full ranking of 25 similar funds is below.

#1Caligan Partners LPSmart money

Substantial overlap · 8 shared positions

$RVMD $TNGX $PCVX $VRDN $TYRA $VOR

$2.1B

28 positions

#2Darwin Global Management, Ltd.Smart money

Substantial overlap · 3 shared positions

$RVMD $BLTE $INSM

$3.8B

5 positions

#3DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)Active

Substantial overlap · 4 shared positions

$NUVL $RVMD $GMAB $TNGX

$9.6B

82 positions

#4DAFNA Capital Management LLCActive

Substantial overlap · 3 shared positions

$RVMD $EWTX $MPLT

$524M

88 positions

#5Affinity Asset Advisors, LLCActive

Substantial overlap · 10 shared positions

$SYRE $APGE $ERAS $ORKA $INSM $RVMD

$2.2B

113 positions

#6Casdin Capital, LLCSmart money

Substantial overlap · 4 shared positions

$RVMD $ALNY $EDIT $KARD

$2.0B

43 positions

#7First Turn Management, LLCActive

Substantial overlap · 8 shared positions

$RVMD $INSM $ERAS $PCVX $VRDN $APGE

$935M

31 positions

#8Deep Track Capital, LPActive

Substantial overlap · 9 shared positions

$GMAB $TARS $NUVL $ALNY $ORKA $PCVX

$6.9B

67 positions

#9VR Adviser, LLCSmart money

Substantial overlap · 8 shared positions

$SYRE $APGE $ORKA $ERAS $VRDN $JBIO

$3.3B

33 positions

#10PERCEPTIVE ADVISORS LLCActive

Substantial overlap · 8 shared positions

$SYRE $NUVL $EWTX $APGE $ORKA $TNGX

$6.7B

109 positions

#11Integral Health Asset Management, LLCActive

Notable overlap · 5 shared positions

$RVMD $EWTX $INSM $TNGX $SYRE

$2.5B

92 positions

#12Cormorant Asset Management, LPActive

Notable overlap · 10 shared positions

$EWTX $ERAS $ORKA $TNGX $MBX $OLMA

$2.0B

50 positions

#13StemPoint Capital LPPassive

Notable overlap · 9 shared positions

$RVMD $TNGX $ERAS $ORKA $SYRE $TYRA

$581M

84 positions

#14Bellevue Group AGActive

Notable overlap · 7 shared positions

$RVMD $ORKA $NUVL $INSM $PCVX $VRDN

$4.8B

148 positions

#15KVP Capital Advisors, LPActive

Notable overlap · 7 shared positions

$EWTX $TNGX $ERAS $MBX $INSM $VRDN

$136M

35 positions

#16Logos Global Management LPActive

Notable overlap · 7 shared positions

$RVMD $TNGX $ERAS $OLMA $BLTE $JBIO

$2.3B

68 positions

#17RTW INVESTMENTS, LPActive

Notable overlap · 7 shared positions

$TNGX $SYRE $ERAS $INSM $ORKA $TARS

$11.7B

84 positions

#18FARALLON CAPITAL MANAGEMENT LLCActive

Notable overlap · 3 shared positions

$RVMD $TNGX $ASMB

$21.7B

89 positions

#19BVF INC/ILActive

Notable overlap · 3 shared positions

$RVMD $OLMA $TYRA

$3.9B

44 positions

#20Rock Springs Capital Management LPActive

Notable overlap · 6 shared positions

$RVMD $INSM $ERAS $ALNY $TARS $MBX

$2.0B

104 positions

#21Siren, L.L.C.Active

Notable overlap · 6 shared positions

$TNGX $RVMD $ERAS $EWTX $SYRE $OLMA

$4.9B

117 positions

#22SUPERSTRING CAPITAL MANAGEMENT LPActive

Notable overlap · 4 shared positions

$GMAB $RVMD $PCVX $MPLT

$158M

32 positions

#23Remedium Capital Partners, LLCSmart money

Notable overlap · 4 shared positions

$SYRE $APGE $ORKA $JBIO

$452M

6 positions

#24Seven Fleet Capital Management LPActive

Notable overlap · 6 shared positions

$RVMD $TNGX $TARS $ERAS $ASMB $EDIT

$606M

96 positions

#25BAKER BROS. ADVISORS LPSmart money

Notable overlap · 4 shared positions

$RVMD $INSM $EWTX $VRDN

$20.0B

84 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.