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Hedge Funds Similar to EcoR1

13F Portfolio OverlapQ2 2026EcoR1 portfolio →
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Most similar hedge funds by 13F overlap

EcoR1 Capital, LLC is an institutional investor managing $2.1B across 33 U.S. equity positions as of Q2 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to EcoR1 are Sanofi, MPM BioImpact, TCG Crossover, with shared positions in $ANAB, $TRAX, $ODTX, $AKTS, $ORIC, $STOK. The full ranking of 25 similar funds is below.

#1SanofiSmart money
Notable overlap · 3 shared positions
$ANAB$TRAX$ODTX
$534M
10 positions
#2MPM BioImpact LLCActive
Notable overlap · 5 shared positions
$AKTS$ORIC$STOK$RLAY$ZURA
$1.6B
37 positions
#3TCG Crossover Management, LLCActive
Notable overlap · 8 shared positions
$CGON$TRAX$MBX$RLAY$AURA$AKTS
$4.2B
54 positions
#4Avidity Partners Management LPSmart money
Notable overlap · 3 shared positions
$CGON$AKTS$PHAT
$624M
45 positions
#5Foresite Capital Management V, LLCActive
Notable overlap · 5 shared positions
$CGON$ODTX$EIKN$PHVS$NRIX
$362M
9 positions
#6SR ONE CAPITAL MANAGEMENT, LPSmart money
Notable overlap · 4 shared positions
$CRSP$ORIC$ZBIO$ODTX
$1.0B
15 positions
#7NEA Management Company, LLCSmart money
Notable overlap · 5 shared positions
$CRSP$ORIC$MBX$ZBIO$PHAT
$1.6B
26 positions
#8Seven Fleet Capital Management LPActive
Notable overlap · 4 shared positions
$CGON$RLAY$PHVS$ERAS
$606M
96 positions
#9Blue Owl Capital Holdings LPActive
Notable overlap · 3 shared positions
$AKTS$ORIC$ERAS
$665M
76 positions
#10Foresite Capital Management VI LLCSmart money
Notable overlap · 3 shared positions
$CGON$AURA$ZURA
$643M
23 positions
#11Palo Alto Investors LPActive
Notable overlap · 4 shared positions
$ANAB$TRAX$STOK$CRSP
$724M
52 positions
#12Opaleye Management Inc.Active
Some overlap · 4 shared positions
$ETON$STOK$MBX$BBOT
$1.1B
58 positions
#13RTW INVESTMENTS, LPActive
Some overlap · 3 shared positions
$CGON$STOK$ERAS
$11.7B
84 positions
#14Trails Edge Capital Partners, LPActive
Some overlap · 4 shared positions
$TRAX$NGNE$AURA$NRIX
$630M
35 positions
#15Redmile Group, LLCSmart money
Some overlap · 8 shared positions
$NGNE$STOK$ZYME$AURA$ODTX$ATRA
$1.5B
39 positions
#16TANG CAPITAL MANAGEMENT LLCActive
Some overlap · 3 shared positions
$ANAB$FULC$STOK
$2.2B
41 positions
#17Affinity Asset Advisors, LLCActive
Some overlap · 5 shared positions
$ANAB$TRAX$RLAY$NRIX$ERAS
$2.2B
113 positions
#18683 Capital Management, LLCActive
Some overlap · 3 shared positions
$ANAB$TRAX$PHAT
$2.0B
153 positions
#19Nextech Invest, Ltd.Smart money
Some overlap · 3 shared positions
$ORIC$ZYME$RLAY
$2.1B
15 positions
#20StemPoint Capital LPPassive
Some overlap · 6 shared positions
$TRAX$CGON$AURA$ZURA$ERAS$SRZN
$581M
84 positions
#21NEXTBio Capital Management LPActive
Some overlap · 3 shared positions
$ORIC$ZBIO$PHVS
$217M
22 positions
#22Logos Global Management LPActive
Some overlap · 3 shared positions
$CGON$CRSP$ERAS
$2.3B
68 positions
#23Elmind Capital, LPActive
Some overlap · 5 shared positions
$LEGN$MBX$RLAY$PHVS$NRIX
$398M
35 positions
#24Kynam Capital Management, LPActive
Some overlap · 5 shared positions
$LEGN$MBX$RLAY$PHVS$NRIX
$1.8B
32 positions
#25Octagon Capital Advisors LPActive
Some overlap · 3 shared positions
$AKTS$PHVS$ERAS
$1.1B
27 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.