How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to SPHERA FUNDS LTD.

13F Portfolio OverlapQ1 2026SPHERA FUNDS LTD. portfolio →

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Most similar hedge funds by 13F overlap

SPHERA FUNDS MANAGEMENT LTD. is an institutional investor managing $630M across 96 U.S. equity positions as of Q1 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to SPHERA FUNDS LTD. are Mivtachim The Workers Social Insurance Fund Ltd. (Under Spec, Migdal Insurance & Financial Ltd., Sofinnova Ventures, with shared positions in $TEVA, $TSEM, $NVMI, $SEDG, $ORA, $CAMT. The full ranking of 25 similar funds is below.

#1Mivtachim The Workers Social Insurance Fund Ltd. (Under SpecActive

Notable overlap · 7 shared positions

$TEVA $TSEM $NVMI $SEDG $ORA $CAMT

$789M

44 positions

#2Migdal Insurance & Financial Holdings Ltd.Active

Notable overlap · 8 shared positions

$TEVA $NVMI $TSEM $CAMT $ORA $AZN

$11.5B

362 positions

#3Sofinnova Ventures IncActive

Notable overlap · 10 shared positions

$RARE $COGT $AZN $BIIB $BBIO $BMRN

$2.6B

74 positions

#4Y.D. More Investments LtdActive

Notable overlap · 7 shared positions

$TSEM $NVMI $TEVA $PANW $CAMT $ORA

$2.6B

474 positions

#5Phoenix Financial Ltd.Active

Notable overlap · 6 shared positions

$TEVA $TSEM $NVMI $CLBT $PANW $AZN

$10.5B

486 positions

#6Catalio Capital Management, LPActive

Notable overlap · 6 shared positions

$BBIO $RARE $SNDX $MLYS $SLNO $ELDN

$479M

41 positions

#7Palo Alto Investors LPActive

Notable overlap · 8 shared positions

$BIIB $SNDX $RARE $FOLD $BMRN $CLDX

$654M

51 positions

#8Ishara Investments LPActive

Notable overlap · 7 shared positions

$RARE $MLYS $FOLD $BMRN $IMTX $ORIC

$106M

37 positions

#9StemPoint Capital LPActive

Notable overlap · 7 shared positions

$SNDX $MLYS $CLDX $XENE $ELVN $ACAD

$515M

82 positions

#10Kynam Capital Management, LPActive

Notable overlap · 6 shared positions

$SNDX $COGT $APLS $BCRX $CLDX $SLNO

$1.6B

39 positions

#11Exome Asset Management LLCPassive

Notable overlap · 6 shared positions

$BBIO $COGT $APLS $SLNO $MAZE $ELVN

$193M

56 positions

#12MENORA MIVTACHIM HOLDINGS LTD.Active

Notable overlap · 4 shared positions

$TEVA $NVMI $CAMT $SEDG

$21.1B

157 positions

#13Vestal Point Capital, LPActive

Notable overlap · 8 shared positions

$SNY $BCRX $BMRN $COGT $IMTX $CLDX

$3.6B

90 positions

#14Affinity Asset Advisors, LLCActive

Notable overlap · 7 shared positions

$TEVA $COGT $XENE $MLYS $TRVI $ELVN

$1.9B

105 positions

#15SILVERARC CAPITAL MANAGEMENT, LLCActive

Notable overlap · 7 shared positions

$COGT $SNDX $XENE $ORIC $BIIB $TRVI

$980M

73 positions

#16Logos Global Management LPActive

Notable overlap · 9 shared positions

$BIIB $XENE $TNGX $TRVI $MAZE $ELVN

$2.0B

66 positions

#17Caligan Partners LPActive

Notable overlap · 5 shared positions

$MLYS $XENE $TNGX $MAZE $VOR

$1.5B

28 positions

#18Elmind Capital, LPActive

Notable overlap · 6 shared positions

$SNDX $COGT $BCRX $CLDX $BMRN $APLS

$352M

34 positions

#19Knott David M JrActive

Notable overlap · 5 shared positions

$BBIO $SNDX $COGT $BIIB $RARE

$168M

85 positions

#20First Turn Management, LLCActive

Notable overlap · 5 shared positions

$BBIO $COGT $XENE $ORIC $ELVN

$895M

33 positions

#21Laurion Capital Management LPPassive

Notable overlap · 3 shared positions

$MLYS $BBIO $VOR

$2.3B

349 positions

#22Deep Track Capital, LPActive

Notable overlap · 8 shared positions

$APLS $BMRN $BBIO $TNGX $MAZE $CLDX

$6.1B

63 positions

#23Altshuler Shaham LtdActive

Notable overlap · 3 shared positions

$TEVA $PANW $TSEM

$5.5B

443 positions

#24Frazier Life Sciences Management, L.P.Smart money

Notable overlap · 6 shared positions

$BBIO $TRVI $MAZE $VOR $BCRX $ACAD

$3.9B

38 positions

#25GordonMD Global Investments LPActive

Notable overlap · 3 shared positions

$TEVA $RARE $CLDX

$144M

16 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.