What hedge funds are most similar to Sio Capital Management, LLC?

The funds with the most similar 13F portfolios to Sio Capital Management, LLC are Cormorant Asset ,, StemPoint, SILVERARC ,, based on overlapping conviction holdings in the latest SEC filings.

How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to Sio ,

13F Portfolio OverlapQ1 2026Sio , portfolio →

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Most similar hedge funds by 13F overlap

Sio Capital Management, LLC is an institutional investor managing $697M across 76 U.S. equity positions as of Q1 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to Sio , are Cormorant Asset ,, StemPoint, SILVERARC ,, with shared positions in $DNTH, $ABVX, $RAPP, $EYPT, $EWTX, $ORKA. The full ranking of 25 similar funds is below.

#1Cormorant Asset Management, LPActive

Notable overlap · 10 shared positions

$DNTH $ABVX $RAPP $EYPT $EWTX $ORKA

$2.0B

47 positions

#2StemPoint Capital LPActive

Notable overlap · 9 shared positions

$ABVX $GPCR $TYRA $BHVN $DNTH $CELC

$515M

82 positions

#3SILVERARC CAPITAL MANAGEMENT, LLCActive

Notable overlap · 5 shared positions

$DNTH $CELC $ABVX $ZBIO $ORKA

$980M

73 positions

#4Soleus Capital Management, L.P.Active

Notable overlap · 7 shared positions

$CELC $ANIP $LIVN $BMRN $EWTX $ICLR

$2.5B

93 positions

#5TANG CAPITAL MANAGEMENT LLCActive

Notable overlap · 5 shared positions

$CELC $CORT $ANIP $DNTH $CMPS

$2.0B

51 positions

#6TCG Crossover Management, LLCActive

Notable overlap · 5 shared positions

$DNTH $TYRA $ABVX $BHVN $OCUL

$3.5B

49 positions

#7Boxer Capital Management, LLCSmart money

Notable overlap · 8 shared positions

$CELC $ABVX $VIR $CORT $REPL $RLMD

$762M

54 positions

#8Parkman Healthcare Partners LLCActive

Notable overlap · 7 shared positions

$LIVN $ANIP $EYPT $GPCR $WAY $EWTX

$970M

90 positions

#9Artia Global Partners LPActive

Notable overlap · 8 shared positions

$DNTH $ABVX $EYPT $SION $RAPP $DRUG

$499M

50 positions

#10ADAR1 Capital Management, LLCPassive

Notable overlap · 7 shared positions

$ABVX $VIR $CRNX $AVR $SNY $MNPR

$1.7B

310 positions

#11Jones Hill Capital LPActive

Notable overlap · 6 shared positions

$ANIP $VIR $BMRN $GPCR $ORKA $RLMD

$466M

26 positions

#12MPM BioImpact LLCActive

Notable overlap · 5 shared positions

$CORT $DNTH $EWTX $ABVX $DRUG

$1.3B

41 positions

#13Propel Bio Management, LLCActive

Notable overlap · 5 shared positions

$CORT $EYPT $CMPS $OCUL $AQST

$159M

38 positions

#14HighVista Strategies LLCPassive

Notable overlap · 7 shared positions

$ABVX $GPCR $TYRA $OCUL $ORKA $DNTH

$362M

156 positions

#15RA CAPITAL MANAGEMENT, L.P.Smart money

Notable overlap · 4 shared positions

$TYRA $DNTH $SION $EWTX

$9.4B

85 positions

#16Avidity Partners Management LPActive

Notable overlap · 8 shared positions

$DNTH $VIR $ORKA $GPCR $ICLR $CORT

$442M

46 positions

#17Catalio Capital Management, LPActive

Notable overlap · 5 shared positions

$DNTH $GPCR $ABVX $TARA $TYRA

$479M

41 positions

#18Seven Fleet Capital Management LPActive

Notable overlap · 3 shared positions

$TYRA $DNTH $ABVX

$315M

114 positions

#19Logos Global Management LPActive

Notable overlap · 5 shared positions

$ABVX $DNTH $TYRA $GPCR $OCUL

$2.0B

66 positions

#20EQUITY INVESTMENT CORPActive

Some overlap · 4 shared positions

$GSK $ICLR $SNY $ZBH

$5.1B

71 positions

#21Octagon Capital Advisors LPActive

Some overlap · 3 shared positions

$DNTH $ABVX $OCUL

$904M

29 positions

#22Patient Square Capital LPSmart money

Some overlap · 5 shared positions

$ABVX $CELC $DNTH $EYPT $TARA

$564M

29 positions

#23Eagle Health Investments LPActive

Some overlap · 3 shared positions

$ICLR $BMRN $CMPS

$572M

28 positions

#24Vestal Point Capital, LPActive

Some overlap · 5 shared positions

$ABVX $SNY $BMRN $RAPP $DRUG

$3.6B

90 positions

#255AM Venture Management, LLCActive

Some overlap · 4 shared positions

$TYRA $TARA $BHVN $EYPT

$360M

20 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.