What hedge funds are most similar to Sio Capital Management, LLC?

The funds with the most similar 13F portfolios to Sio Capital Management, LLC are EQUITY INVESTMENT, StemPoint, Vestal Point, based on overlapping conviction holdings in the latest SEC filings.

How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to Sio

13F Portfolio OverlapQ2 2026Sio portfolio →

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Most similar hedge funds by 13F overlap

Sio Capital Management, LLC is an institutional investor managing $604M across 59 U.S. equity positions as of Q2 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to Sio are EQUITY INVESTMENT, StemPoint, Vestal Point, with shared positions in $GSK, $ICLR, $SNY, $ZBH, $MDT, $TYRA. The full ranking of 25 similar funds is below.

#1EQUITY INVESTMENT CORPActive

Notable overlap · 5 shared positions

$GSK $ICLR $SNY $ZBH $MDT

$5.2B

76 positions

#2StemPoint Capital LPPassive

Notable overlap · 7 shared positions

$TYRA $ORKA $CELC $RLMD $TNGX $DNTH

$581M

84 positions

#3Vestal Point Capital, LPActive

Notable overlap · 8 shared positions

$SNY $ABT $ZBH $GMED $BMY $DRUG

$4.3B

68 positions

#4Sivik Global Healthcare LLCActive

Notable overlap · 4 shared positions

$COR $GMED $ABT $REGN

$132M

34 positions

#5Defilade Capital Management, L.P.Active

Notable overlap · 6 shared positions

$ABT $ZBH $MDT $TYRA $GMED $OCUL

$747M

39 positions

#6SECTOR GAMMA ASActive

Notable overlap · 5 shared positions

$ABT $ZBH $REGN $BMY $MDT

$461M

40 positions

#7Cormorant Asset Management, LPActive

Notable overlap · 6 shared positions

$ORKA $RAPP $EYPT $TNGX $DNTH $DRUG

$2.0B

50 positions

#8DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)Active

Notable overlap · 6 shared positions

$VTRS $CELC $IDYA $TNGX $DNTH $SVRA

$9.6B

82 positions

#9Keystone Financial Planning, Inc.Smart money

Notable overlap · 4 shared positions

$GSK $BMY $MDT $SNY

$388M

39 positions

#10Bellevue Group AGActive

Notable overlap · 4 shared positions

$ORKA $REGN $ABT $MDT

$4.8B

148 positions

#11Aurdan Capital Management, LLCActive

Notable overlap · 3 shared positions

$COR $ABT $BMY

$394M

99 positions

#12Krensavage Asset Management, LLCActive

Some overlap · 4 shared positions

$SNY $ABT $GSK $REGN

$263M

18 positions

#13LAKEWOOD CAPITAL MANAGEMENT, LPActive

Some overlap · 3 shared positions

$CI $ICLR $VTRS

$1.9B

65 positions

#14Hillman Capital Management, Inc.Passive

Some overlap · 4 shared positions

$GSK $ZBH $BMY $MDT

$138M

54 positions

#15Sofinnova Ventures IncActive

Some overlap · 6 shared positions

$RAPP $BMY $IDYA $GMED $ABT $SION

$1.9B

57 positions

#16GordonMD Global Investments LPActive

Some overlap · 3 shared positions

$ALLO $VIR $SION

$207M

16 positions

#17SILVERARC CAPITAL MANAGEMENT, LLCActive

Some overlap · 5 shared positions

$ORKA $CELC $DNTH $ZBIO $SVRA

$962M

73 positions

#18VR Adviser, LLCSmart money

Some overlap · 6 shared positions

$ORKA $RLMD $DNTH $OCUL $HELP $SVRA

$3.3B

33 positions

#19Avidity Partners Management LPSmart money

Some overlap · 6 shared positions

$ORKA $SENS $DNTH $MDT $VIR $ABT

$624M

45 positions

#20Altrius Capital Management IncPassive

Some overlap · 3 shared positions

$GSK $SNY $ABT

$526M

89 positions

#21Artia Global Partners LPActive

Some overlap · 7 shared positions

$EYPT $CELC $RAPP $DNTH $SION $ORKA

$542M

48 positions

#22Parkman Healthcare Partners LLCActive

Some overlap · 5 shared positions

$ZBH $EYPT $ANIP $ORKA $DRUG

$977M

77 positions

#23Commodore Capital LPActive

Some overlap · 4 shared positions

$TYRA $EYPT $TNGX $RLMD

$1.7B

33 positions

#24HealthInvest Partners ABActive

Some overlap · 5 shared positions

$COR $ORKA $TNGX $IDYA $CELC

$372M

39 positions

#25PFIZER INCSmart money

Some overlap · 3 shared positions

$ALLO $CELC $SENS

$170M

17 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.