Hedge Funds Similar to ORBIMED ADVISORS

13F Portfolio OverlapQ1 2026ORBIMED ADVISORS portfolio →
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Most similar hedge funds by 13F overlap

ORBIMED ADVISORS LLC is an institutional investor managing $5.0B across 112 U.S. equity positions as of Q1 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to ORBIMED ADVISORS are Novo A/S, Catalio ,, StemPoint, with shared positions in $EWTX, $ELVN, $AVBP, $XENE, $CRNX, $BSX. The full ranking of 25 similar funds is below.

Notable overlap · 5 shared positions
$1.2B
22 positions
Notable overlap · 11 shared positions
$479M
41 positions
Notable overlap · 10 shared positions
$515M
82 positions
Notable overlap · 11 shared positions
$4.2B
155 positions
Notable overlap · 10 shared positions
$1.7B
100 positions
Notable overlap · 9 shared positions
$970M
90 positions
#7BRAIDWELL LPPassive
Notable overlap · 9 shared positions
$3.0B
88 positions
Notable overlap · 11 shared positions
$2.6B
74 positions
Notable overlap · 7 shared positions
$9.4B
85 positions
Notable overlap · 7 shared positions
$1.2B
45 positions
Notable overlap · 9 shared positions
$121M
77 positions
Notable overlap · 8 shared positions
$810M
86 positions
Notable overlap · 6 shared positions
$193M
56 positions
Notable overlap · 9 shared positions
$315M
114 positions
Notable overlap · 8 shared positions
$3.6B
90 positions
Notable overlap · 7 shared positions
$310M
39 positions
Notable overlap · 8 shared positions
$2.0B
47 positions
Notable overlap · 8 shared positions
$2.1B
90 positions
#19Siren, L.L.C.Active
Notable overlap · 7 shared positions
$3.6B
100 positions
Notable overlap · 9 shared positions
$2.0B
66 positions
Notable overlap · 6 shared positions
$134M
32 positions
Notable overlap · 6 shared positions
$1.3B
41 positions
Notable overlap · 8 shared positions
$499M
50 positions
Notable overlap · 3 shared positions
$1.7B
36 positions
Notable overlap · 7 shared positions
$895M
33 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.