SERA PROGNOSTICS, INC.(SERA)Stock Analysis
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Rank #2,829 of 2,879 stocks
Rankings refresh quarterly once 80% of peers have filed (~45 days after quarter-end). Next update: ~Aug 14, 2026.
Revenue Growth
Profitability
Balance Sheet
Earnings Quality
Free Cash Flow
Institutional Flow
Revenue Scale
Dilution Risk
SERA Stock Analysis & AI Quality Score
AI stock analysis and institutional research for SERA PROGNOSTICS, INC. (SERA), a Healthcare sector company. 13F Pro's AI-powered ranking engine scores SERA at 7.9/100 on a 32-signal composite quality model, placing it at rank #2,829 of 2,879 stocks — the bottom half of the AI-ranked universe. SERA scores in the top quartile across institutional flow (96.5). Areas of concern include free cash flow (0.1) and revenue scale (0.2), which score below median versus the broader universe. Shareholder dilution risk is elevated at 0.2/100, reflecting ongoing share issuance or stock-based compensation. Based on the latest XBRL financial filings (Q1 2026), SERA PROGNOSTICS, INC. reports quarterly revenue of $14.0K, net income of $-8.4M, free cash flow of $-8.8M. Top institutional holders of SERA by reported 13-F value include BAKER BROS. ADVISORS, Whetstone Capital Advisors,, abrdn plc, based on the most recent SEC filings. SERA trades on the Nasdaq exchange and files with the SEC under CIK 1534969. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate SERA daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for SERA PROGNOSTICS, INC. directly from SEC EDGAR. SERA PROGNOSTICS, INC.'s 13F Pro composite quality score has ranged between 5 and 29 since 2022, currently 7.9 — a declining long-term trajectory across 16 quarterly and live scoring snapshots.
Revenue
Q1 2026
$14.0K
Net Income
Q1 2026
$-8.4M
Free Cash Flow
Q1 2026
$-8.8M
Revenue & Net Income
Earnings Per Share
Key Financials Over Time
Export Financial Table · Pro+Revenue
-69.8% YoYNet Income
+27.7% YoYOperating Income
+20.0% YoYEPS (Diluted)
+53.1% YoYTotal Assets
-12.4% YoYOp. Cash Flow
+26.0% YoY| Metric | FY 2025 | FY 2022 |
|---|---|---|
| Revenue | $81.0K -69.8% | $268.0K |
| Net Income | $-31.9M +27.7% | $-44.2M |
| Operating Income | $-36.5M +20.0% | $-45.7M |
| EPS (Diluted) | $-0.67 +53.1% | $-1.43 |
| Total Assets | $101.9M -12.4% | $116.3M |
| Operating Cash Flow | $-25.6M +26.0% | $-34.6M |
AI Insight: SERA Financial Trends
Pre-revenue SERA burns ~$6–9M operating cash per quarter with equity eroding steadily toward $68M — runway is the only metric that matters.
• Revenue has been $0M across all eight quarters from Q2 2024 through Q1 2026 — no commercialization progress visible in financials.
• Equity fell from $95M in Q1 2025 to $68M in Q1 2026, a $27M decline in four quarters driven entirely by operating losses.
• Operating cash outflow spiked to -$9M in Q1 2026, the worst quarter in the dataset, after holding at -$5M to -$7M prior.
⚠ At the Q1 2026 burn rate of -$9M/quarter, remaining equity of $68M implies roughly 7–8 quarters before capital is exhausted.
⚠ No debt appears on the balance sheet; any debt raise to extend runway would introduce leverage risk not yet present.
⚠ A Q1 2025 equity jump from $48M to $95M signals a capital raise — monitor for any similar dilutive financing in coming quarters.
AI Insight: SERA Ratio Trends
SERA's return metrics remain deeply negative across all periods, though a meaningful improvement from Q4 2024 trough levels offers a tentative floor.
• ROE deteriorated from -55.6% in Q2 2024 to a trough of -71.8% in Q4 2024, before recovering to -34.5% in Q1 2025.
• ROIC followed the same arc: -64.9% in Q3 2024, bottoming at -78.8% in Q4 2024, then improving to -39.0% in Q1 2025.
• Since Q1 2025, ROE has re-deteriorated from -34.5% to -49.7% in Q1 2026, reversing the post-trough recovery.
⚠ ROIC at -55.4% in Q1 2026 is approaching the Q4 2024 trough of -78.8% — renewed deterioration trend warrants close monitoring.
⚠ OpMargin, NPM, and D/E are entirely absent across all periods, severely limiting visibility into operational performance and leverage.
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Available Research
13F Pro tracks comprehensive data for SERA PROGNOSTICS, INC. including:
Top Institutional Holders of SERA
BAKER BROS. ADVISORS LP
$11.2M5,498,170 shWhetstone Capital Advisors, LLC
$6.7M3,306,889 shabrdn plc
$5.2M2,550,775 shPSP Research LLC
$4.9M2,396,685 shVivo Capital, LLC
$3.4M1,650,440 shVANGUARD CAPITAL MANAGEMENT LLC
$2.4M1,204,115 shCAPTRUST FINANCIAL ADVISORS
$1.1M536,761 shGEODE CAPITAL MANAGEMENT, LLC
$738.5K363,617 shSANDERS MORRIS HARRIS LLC
$639.3K314,950 shCITADEL ADVISORS LLC
$505.3K248,909 sh
| Fund | Value | Shares |
|---|---|---|
| BAKER BROS. ADVISORS LP | $11.2M | 5,498,170 |
| Whetstone Capital Advisors, LLC | $6.7M | 3,306,889 |
| abrdn plc | $5.2M | 2,550,775 |
| PSP Research LLC | $4.9M | 2,396,685 |
| Vivo Capital, LLC | $3.4M | 1,650,440 |
| VANGUARD CAPITAL MANAGEMENT LLC | $2.4M | 1,204,115 |
| CAPTRUST FINANCIAL ADVISORS | $1.1M | 536,761 |
| GEODE CAPITAL MANAGEMENT, LLC | $738.5K | 363,617 |
| SANDERS MORRIS HARRIS LLC | $639.3K | 314,950 |
| CITADEL ADVISORS LLC | $505.3K | 248,909 |
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Popular Research
Is SERA a good stock to buy?
13F Pro's AI-powered analysis of SERA PROGNOSTICS, INC. (SERA) draws on SEC EDGAR-sourced fundamentals, institutional 13F holdings, and insider Form 4 transactions in the Healthcare sector (listed on Nasdaq). The 32-signal AI Quality Score, current rank, and full bull/bear verdict for SERA are available on the SERA stock profile dashboard — with the same data, AI insights, ratios, and institutional activity refreshed after every 10-K, 10-Q, 13F, and Form 4 filing.
Which hedge funds own SERA?
Institutional investors are required to disclose their holdings quarterly via SEC Form 13F. 13F Pro aggregates these filings to show which hedge funds, mutual funds, and asset managers are buying or selling SERA. Combined with insider transaction data from Form 4 filings and AI-powered analysis from 10 specialized research agents, 13F Pro provides a comprehensive view of SERA PROGNOSTICS, INC.'s investment landscape.