aTYR PHARMA INC(ATYR)Stock Analysis
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Quality rankings require at least $50M annual revenue or $250M total assets to filter out micro-caps and shell companies. This company reported $10.5M in revenue.
Financial data, filings, and institutional holdings below are still tracked in full — only the proprietary quality composite is unavailable for this name.
ATYR Stock Analysis & AI Quality Score
AI stock analysis and institutional research for aTYR PHARMA INC (ATYR), a Healthcare sector company. ATYR is not currently included in 13F Pro's AI-ranked quality universe — quality rankings require at least $50m annual revenue or $250m total assets to filter out micro-caps and shell companies. this company reported $10.5m in revenue. Based on the latest XBRL financial filings (Q1 2026), aTYR PHARMA INC reports net income of $-10.8M, free cash flow of $-12.7M. Top institutional holders of ATYR by reported 13-F value include FMR, FEDERATED HERMES,, BlackRock,, based on the most recent SEC filings. ATYR trades on the Nasdaq exchange and files with the SEC under CIK 1339970. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate ATYR daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for aTYR PHARMA INC directly from SEC EDGAR.
Net Income
Q1 2026
$-10.8M
Free Cash Flow
Q1 2026
$-12.7M
Revenue & Net Income
Earnings Per Share
Key Financials Over Time
Export Financial Table · Pro+Revenue
-19.1% YoYNet Income
-15.8% YoYOperating Income
-14.3% YoYEPS (Diluted)
+7.0% YoYTotal Assets
-4.0% YoYTotal Debt
Op. Cash Flow
+10.3% YoY| Metric | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2019 |
|---|---|---|---|---|---|---|
| Revenue | $190.0K -19.1% | $235.0K -33.4% | $353.0K -96.6% | $10.4M | $0.00 -100.0% | $422.0K |
| Net Income | $-74.1M -15.8% | $-64.0M -27.1% | $-50.4M -11.1% | $-45.3M -34.3% | $-33.8M -108.1% | $-16.2M |
| Operating Income | $-77.6M -14.3% | $-67.9M -23.7% | $-54.9M -18.3% | $-46.4M -36.4% | $-34.0M -48.0% | $-23.0M |
| EPS (Diluted) | $-0.80 +7.0% | $-0.86 +8.5% | $-0.94 +41.3% | $-1.60 +9.6% | $-1.77 | — |
| Total Assets | $93.0M -4.0% | $96.8M -19.7% | $120.7M +26.0% | $95.8M -17.1% | $115.5M +219.3% | $36.2M |
| Total Debt | — | — | — | — | — | $8.7M |
| Operating Cash Flow | $-62.0M +10.3% | $-69.1M -108.1% | $-33.2M +20.7% | $-41.9M -26.6% | $-33.1M -65.3% | $-20.0M |
AI Insight: ATYR Financial Trends
Pre-revenue biotech burning cash consistently with no commercialization in sight; equity base eroding quarterly.
• Zero revenue across all periods; company remains entirely pre-commercial with no product launches evident.
• Operating losses stable at $11M–$27M per quarter; Q1 2026 shows modest $11M op loss, best in recent quarters.
• Equity declined from $82M (Q2 2024) to $58M (Q1 2026), a 29% contraction driven by cumulative net losses.
⚠ Operating cash burn averaged $15M/quarter; runway visibility depends on cash reserves not shown in table.
⚠ Q3 2025 peak net loss of $26M suggests elevated R&D spend; sustainability of current burn rate unclear.
AI Insight: ATYR Ratio Trends
aTYR remains deeply unprofitable with no clear path to positive returns; Q1 2026 shows modest improvement in losses but profitability remains years away.
• ROE improved from -128.3% (Q3 2025) to -74.5% (Q1 2026); ROA similarly improved from -96.5% to -54.2%.
• ROIC moved from -90.4% (Q4 2024) to -79.0% (Q1 2026), indicating persistent capital destruction across the period.
⚠ Operating margins, NPM, and D/E ratios unavailable; cash burn trajectory and debt levels cannot be assessed from available data.
⚠ Q3 2025 marked a trough (-128.3% ROE, -96.5% ROA); recovery has begun but company remains loss-making with no visible inflection.
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Available Research
13F Pro tracks comprehensive data for aTYR PHARMA INC including:
Top Institutional Holders of ATYR
FMR LLC
$11.5M14,706,843 shFEDERATED HERMES, INC.
$8.2M10,509,678 shBlackRock, Inc.
$5.0M6,443,904 shUBS Group AG
$3.0M3,867,213 shVANGUARD CAPITAL MANAGEMENT LLC
$3.0M3,812,132 shGEODE CAPITAL MANAGEMENT, LLC
$1.9M2,385,485 shSTATE STREET CORP
$1.4M1,754,399 shMILLENNIUM MANAGEMENT LLC
$1.3M1,641,246 shMORGAN STANLEY
$955.9K1,225,467 shTWO SIGMA INVESTMENTS, LP
$892.8K1,144,565 sh
| Fund | Value | Shares |
|---|---|---|
| FMR LLC | $11.5M | 14,706,843 |
| FEDERATED HERMES, INC. | $8.2M | 10,509,678 |
| BlackRock, Inc. | $5.0M | 6,443,904 |
| UBS Group AG | $3.0M | 3,867,213 |
| VANGUARD CAPITAL MANAGEMENT LLC | $3.0M | 3,812,132 |
| GEODE CAPITAL MANAGEMENT, LLC | $1.9M | 2,385,485 |
| STATE STREET CORP | $1.4M | 1,754,399 |
| MILLENNIUM MANAGEMENT LLC | $1.3M | 1,641,246 |
| MORGAN STANLEY | $955.9K | 1,225,467 |
| TWO SIGMA INVESTMENTS, LP | $892.8K | 1,144,565 |
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Popular Research
Is ATYR a good stock to buy?
13F Pro's AI-powered analysis of aTYR PHARMA INC (ATYR) draws on SEC EDGAR-sourced fundamentals, institutional 13F holdings, and insider Form 4 transactions in the Healthcare sector (listed on Nasdaq). The 32-signal AI Quality Score, current rank, and full bull/bear verdict for ATYR are available on the ATYR stock profile dashboard — with the same data, AI insights, ratios, and institutional activity refreshed after every 10-K, 10-Q, 13F, and Form 4 filing.
Which hedge funds own ATYR?
Institutional investors are required to disclose their holdings quarterly via SEC Form 13F. 13F Pro aggregates these filings to show which hedge funds, mutual funds, and asset managers are buying or selling ATYR. Combined with insider transaction data from Form 4 filings and AI-powered analysis from 10 specialized research agents, 13F Pro provides a comprehensive view of aTYR PHARMA INC's investment landscape.