SEC Form 4 reporting owner

Henderson Michael Thomas

Henderson Michael Thomas has filed 43 Form 4 transactions reported between December 4, 2025 and September 3, 2026, as Chief Executive Officer of Apogee Therapeutics, Inc. and Director of Spyre Therapeutics, Inc..

Name as filed: HENDERSON MICHAEL THOMAS

Open-market buys, 24 mo
None
reported
Open-market sales, 24 mo
$35.1M
34 lines
Companies
2
with Form 4 filings
Latest transaction
Sep 3, 2026
transaction date

Roles and reported holdings

  • APGEApogee Therapeutics, Inc.
    Dec 4, 2025 – Sep 3, 2026

    Chief Executive Officer

    Held directly920,941 sh as of Jul 10, 2026 · Form 4

    24 months: $27.1M sold

  • SYRESpyre Therapeutics, Inc.
    Jan 21, 2026 – Jun 22, 2026

    Director

    Held directly68,606 sh as of Jun 22, 2026 · Form 4

    24 months: $8.0M sold

Transaction history

All 43 reported transactions, newest first. Every row links to the Form 4 on SEC EDGAR.

DateCompanyTypeSharesValueFiling
Sep 3, 2026APGEChief Executive OfficerDisposition to issuerCode D · direct253,016—Form 4
Sep 3, 2026APGEChief Executive OfficerDisposition to issuerCode D · direct357,036—Form 4
Sep 3, 2026APGEChief Executive OfficerDisposition to issuerCode D · direct387,012—Form 4
Sep 3, 2026APGEChief Executive OfficerDisposition to issuerCode D · direct920,941—Form 4
Jul 10, 2026APGEChief Executive OfficerGiftCode G · direct75,046—Form 4
Jul 8, 2026APGEChief Executive OfficerOpen-market saleCode S · direct20,000$2.7M@ $133.63Form 4
Jun 22, 2026SYREDirectorOpen-market saleCode S · direct20,000$2.0M@ $100.00Form 4
Jun 22, 2026APGEChief Executive OfficerOpen-market saleCode S · direct80,000$10.6M@ $132.54Form 4
Jun 10, 2026APGEChief Executive OfficerOpen-market saleCode S · direct614$53K@ $86.89Form 4
Jun 10, 2026APGEChief Executive OfficerOpen-market saleCode S · direct2,305$199K@ $86.27Form 4
Jun 10, 2026APGEChief Executive OfficerOpen-market saleCode S · direct1,577$134K@ $85.19Form 4
Jun 10, 2026APGEChief Executive OfficerOpen-market saleCode S · direct1,080$91K@ $84.18Form 4
Jun 10, 2026APGEChief Executive OfficerOpen-market saleCode S · direct7,654$634K@ $82.78Form 4
Jun 10, 2026APGEChief Executive OfficerOpen-market saleCode S · direct6,770$557K@ $82.21Form 4
May 27, 2026SYREDirectorGrant or awardCode A · direct8,026—Form 4
May 13, 2026APGEChief Executive OfficerOpen-market saleCode S · direct1,341$111K@ $82.58Form 4
May 13, 2026APGEChief Executive OfficerOpen-market saleCode S · direct18,659$1.5M@ $82.05Form 4
May 8, 2026SYREDirectorOpen-market saleCode S · direct19,269$1.5M@ $75.35Form 4
May 8, 2026SYREDirectorOpen-market saleCode S · direct24,814$1.9M@ $74.76Form 4
May 8, 2026SYREDirectorOpen-market saleCode S · direct33,513$2.5M@ $73.72Form 4
May 8, 2026SYREDirectorOpen-market saleCode S · direct2,404$174K@ $72.57Form 4
Apr 16, 2026APGEChief Executive OfficerOption exerciseCode M · direct3,000$69K@ $22.86Form 4
Apr 8, 2026APGEChief Executive OfficerOpen-market saleCode S · direct200$17K@ $85.00Form 4
Apr 8, 2026APGEChief Executive OfficerOpen-market saleCode S · direct2,000$167K@ $83.26Form 4
Apr 8, 2026APGEChief Executive OfficerOpen-market saleCode S · direct17,800$1.5M@ $82.48Form 4
Mar 11, 2026APGEChief Executive OfficerOpen-market saleCode S · direct3,418$259K@ $75.86Form 4
Mar 11, 2026APGEChief Executive OfficerOpen-market saleCode S · direct8,219$615K@ $74.83Form 4
Mar 11, 2026APGEChief Executive OfficerOpen-market saleCode S · direct8,363$621K@ $74.29Form 4
Feb 11, 2026APGEChief Executive OfficerOpen-market saleCode S · direct955$62K@ $64.99Form 4
Feb 11, 2026APGEChief Executive OfficerOpen-market saleCode S · direct7,551$481K@ $63.73Form 4
Feb 11, 2026APGEChief Executive OfficerOpen-market saleCode S · direct11,494$724K@ $62.96Form 4
Jan 21, 2026SYREDirectorOther acquisition or dispositionCode J · direct63,227—Form 4
Jan 14, 2026APGEChief Executive OfficerOpen-market saleCode S · direct470$39K@ $83.79Form 4
Jan 14, 2026APGEChief Executive OfficerOpen-market saleCode S · direct5,386$448K@ $83.16Form 4
Jan 14, 2026APGEChief Executive OfficerOpen-market saleCode S · direct1,854$153K@ $82.41Form 4
Jan 14, 2026APGEChief Executive OfficerOpen-market saleCode S · direct2,374$192K@ $81.00Form 4
Jan 14, 2026APGEChief Executive OfficerOpen-market saleCode S · direct8,476$677K@ $79.82Form 4
Jan 14, 2026APGEChief Executive OfficerOpen-market saleCode S · direct1,440$113K@ $78.64Form 4
Jan 2, 2026APGEChief Executive OfficerGrant or awardCode A · direct253,016—Form 4
Dec 10, 2025APGEChief Executive OfficerOpen-market saleCode S · direct560$43K@ $76.58Form 4
Dec 10, 2025APGEChief Executive OfficerOpen-market saleCode S · direct10,005$758K@ $75.79Form 4
Dec 10, 2025APGEChief Executive OfficerOpen-market saleCode S · direct9,435$706K@ $74.88Form 4
Dec 4, 2025APGEChief Executive OfficerOpen-market saleCode S · direct40,000$3.0M@ $75.01Form 4

How this page is built

Every row comes from a Form 4 filed with the SEC, which officers, directors and holders of more than 10% of a company’s stock must file within two business days of a trade. Transactions are grouped by the reporting owner’s name as filed (spacing, capitals and punctuation ignored); two different people filing under an identical name would appear together, and one person filing under two spellings appears on two pages.

Open-market totals count code P purchases and code S sales over the last 24 months. The same trade reported on more than one filing is counted once; when another owner (for example a fund and its general partner) reports the identical trade, they are listed beside it. Holdings are the shares owned after the latest purchase, sale, gift or tax-withholding line, shown separately for direct and indirect ownership; an indirect figure is one holding line, not a total across every trust or entity.

This page describes what was filed with the SEC; it is not investment advice or a recommendation to buy or sell any security.