SEC Form 4 reporting owner

Burrows Scott L

Burrows Scott L has filed 28 Form 4 transactions reported between January 9, 2026 and September 2, 2026, as Chief Financial Officer of Spyre Therapeutics, Inc..

Name as filed: Burrows Scott L

Open-market buys, 24 mo

None

reported

Open-market sales, 24 mo

$6.0M

19 lines

Companies

with Form 4 filings

Latest transaction

Sep 2, 2026

transaction date

Roles and reported holdings

SYRESpyre Therapeutics, Inc.
Jan 9, 2026 – Sep 2, 2026
Chief Financial Officer
Held directly79,762 sh as of Sep 2, 2026 · Form 4
24 months: $6.0M sold

Transaction history

All 28 reported transactions, newest first. Every row links to the Form 4 on SEC EDGAR.

Date	Company	Type	Shares	Price	Value	Owned after	Filing
Sep 2, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	18,232	$89.35	$1.6M@ $89.35	79,762	Form 4
Sep 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	200	$89.04	$18K@ $89.04	97,994	Form 4
Sep 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	2,016	$88.03	$177K@ $88.03	98,194	Form 4
Sep 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	4,384	$87.11	$382K@ $87.11	100,210	Form 4
Sep 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	900	$86.25	$78K@ $86.25	104,594	Form 4
Sep 1, 2026	SYREChief Financial Officer	Option exerciseCode M · direct	7,500	$14.50	$109K@ $14.50	105,494	Form 4
Aug 3, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	100	$97.10	$10K@ $97.10	97,994	Form 4
Aug 3, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	2,300	$96.30	$221K@ $96.30	98,094	Form 4
Aug 3, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	5,100	$95.21	$486K@ $95.21	100,394	Form 4
Aug 3, 2026	SYREChief Financial Officer	Option exerciseCode M · direct	7,500	$14.50	$109K@ $14.50	105,494	Form 4
Jul 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	1,725	$88.37	$152K@ $88.37	97,994	Form 4
Jul 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	5,775	$87.55	$506K@ $87.55	99,719	Form 4
Jul 1, 2026	SYREChief Financial Officer	Option exerciseCode M · direct	7,500	$14.50	$109K@ $14.50	105,494	Form 4
Jun 25, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	10,000	$87.14	$871K@ $87.14	97,994	Form 4
Jun 25, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	5,000	$87.12	$436K@ $87.12	107,994	Form 4
Jun 25, 2026	SYREChief Financial Officer	Option exerciseCode M · direct	15,000	$14.50	$218K@ $14.50	112,994	Form 4
Jun 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	3,100	$72.06	$223K@ $72.06	97,994	Form 4
Jun 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	2,599	$70.77	$184K@ $70.77	101,094	Form 4
Jun 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	1,801	$69.75	$126K@ $69.75	103,693	Form 4
Jun 1, 2026	SYREChief Financial Officer	Option exerciseCode M · direct	7,500	$14.50	$109K@ $14.50	105,494	Form 4
May 1, 2026	SYREChief Financial Officer	Option exerciseCode M · direct	12,500	$14.50	$181K@ $14.50	110,494	Form 4
Apr 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	1,300	$49.98	$65K@ $49.98	97,994	Form 4
Apr 1, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	6,200	$49.21	$305K@ $49.21	99,294	Form 4
Apr 1, 2026	SYREChief Financial Officer	Option exerciseCode M · direct	7,500	$14.50	$109K@ $14.50	105,494	Form 4
Mar 3, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	200	$41.66	$8K@ $41.66	97,994	Form 4
Mar 3, 2026	SYREChief Financial Officer	Open-market saleCode S · direct	2,300	$40.56	$93K@ $40.56	98,194	Form 4
Mar 3, 2026	SYREChief Financial Officer	Option exerciseCode M · direct	2,500	$14.50	$36K@ $14.50	100,494	Form 4
Jan 9, 2026	SYREChief Financial Officer	Grant or awardCode A · direct	140,000	—	—	140,000	Form 4

How this page is built

Every row comes from a Form 4 filed with the SEC, which officers, directors and holders of more than 10% of a company’s stock must file within two business days of a trade. Transactions are grouped by the reporting owner’s name as filed (spacing, capitals and punctuation ignored); two different people filing under an identical name would appear together, and one person filing under two spellings appears on two pages.

Open-market totals count code P purchases and code S sales over the last 24 months. The same trade reported on more than one filing is counted once; when another owner (for example a fund and its general partner) reports the identical trade, they are listed beside it. Holdings are the shares owned after the latest purchase, sale, gift or tax-withholding line, shown separately for direct and indirect ownership; an indirect figure is one holding line, not a total across every trust or entity.

This page describes what was filed with the SEC; it is not investment advice or a recommendation to buy or sell any security.