Xencor Inc (XNCR) — Institutional Holders, Q2 2026

209 institutional investment managers reported a XNCR position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $1.4B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← XNCR stock profile

XNCR in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

Added to

Trimmed

Sold out

Biggest buyers

PRICE T ROWE ASSOCIATESAdded · +795,989 sh+$12.8M
BlackRockAdded · +615,343 sh+$9.9M
STATE STREETAdded · +601,980 sh+$9.7M
Deep Track CapitalNew · +593,551 sh+$9.6M
RA CAPITAL MANAGEMENT, L.P.Added · +377,037 sh+$6.1M

Biggest sellers

EcoR1 CapitalSold out · -2,183,000 sh-$35.1M
VANGUARD PORTFOLIO MANAGEMENTTrimmed · -1,284,652 sh-$20.7M
Lynx1 Capital ManagementTrimmed · -518,204 sh-$8.3M
Erste Asset Management GmbHTrimmed · -338,000 sh-$5.4M
JACOBS LEVY EQUITY MANAGEMENTSold out · -293,080 sh-$4.7M

XNCR 13F holders ranked 1–100 of 209

Institutional investors reporting a position in Xencor Inc on SEC Form 13F-HR for Q2 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q1 2026
1	BlackRock#1 · 13,651,261 sh	13,651,261	$219.8M	<0.01%	+4.7%
2	PRIMECAP MANAGEMENT#2 · 10,181,322 sh	10,181,322	$163.9M	0.10%	-1.5%
3	BVF#3 · 7,133,720 sh	7,133,720	$114.9M	2.94%	0.0%
4	RTW INVESTMENTS#4 · 6,777,461 sh	6,777,461	$109.1M	0.93%	0.0%
5	RA CAPITAL MANAGEMENT, L.P.#5 · 5,274,274 sh	5,274,274	$84.9M	0.74%	+7.7%
6	STATE STREET#6 · 4,954,016 sh	4,954,016	$79.8M	<0.01%	+13.8%
7	VANGUARD CAPITAL MANAGEMENT#7 · 3,278,802 sh	3,278,802	$52.8M	<0.01%	+5.7%
8	TCG Crossover Management#8 · 2,452,138 sh	2,452,138	$39.5M	0.95%	0.0%
9	PRICE T ROWE ASSOCIATES#9 · 2,356,409 sh	2,356,409	$37.9M	<0.01%	+51.0%
10	VANGUARD PORTFOLIO MANAGEMENT#10 · 2,215,690 sh	2,215,690	$35.7M	<0.01%	-36.7%
11	GEODE CAPITAL MANAGEMENT#11 · 1,920,859 sh	1,920,859	$30.9M	<0.01%	+5.8%
12	MORGAN STANLEY#12 · 1,752,556 sh	1,752,556	$28.2M	<0.01%	+12.5%
13	UBS Group AG#13 · 1,306,174 sh	1,306,174	$21.0M	<0.01%	+20.7%
14	BAKER BROS. ADVISORS#14 · 1,102,106 sh	1,102,106	$17.7M	0.09%	0.0%
15	Legal & General Group Plc#15 · 1,091,177 sh	1,091,177	$17.6M	<0.01%	+2.3%
16	DIMENSIONAL FUND ADVISORS#16 · 1,011,119 sh	1,011,119	$16.3M	<0.01%	-21.9%
17	GOLDMAN SACHS GROUP#17 · 968,778 sh	968,778	$15.6M	<0.01%	+26.8%
18	MILLENNIUM MANAGEMENT#18 · 853,677 sh	853,677	$13.7M	<0.01%	+40.0%
19	TWO SIGMA INVESTMENTS#19 · 819,515 sh	819,515	$13.2M	<0.01%	+1.7%
20	NORTHERN#20 · 794,279 sh	794,279	$12.8M	<0.01%	+6.7%
21	JOHNSON & JOHNSON#21 · 748,062 sh	748,062	$12.0M	—	0.0%
22	LEUCADIA NATIONAL#22 · 720,440 sh	720,440	$11.6M	0.08%	0.0%
23	CHARLES SCHWAB INVESTMENT MANAGEMENT#23 · 707,242 sh	707,242	$11.4M	<0.01%	+1.5%
24	PANAGORA ASSET MANAGEMENT#24 · 680,182 sh	680,182	$11.0M	0.03%	+9.6%
25	Deep Track Capital#25 · 593,551 sh	593,551	$9.6M	0.14%	New
26	TORONTO DOMINION BANK#26 · 491,000 sh	491,000	$7.9M	<0.01%	0.0%
27	VANGUARD FIDUCIARY#27 · 487,084 sh	487,084	$7.8M	<0.01%	+3.4%
28	Seven Fleet Capital Management#28 · 368,305 sh	368,305	$7.8M	1.29%	+360.4%
29	AQR CAPITAL MANAGEMENT#29 · 483,834 sh	483,834	$7.8M	<0.01%	+197.9%
30	Bank of New York Mellon#30 · 410,769 sh	410,769	$6.6M	<0.01%	+3.7%
31	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#31 · 382,094 sh	382,094	$6.2M	<0.01%	+214.9%
32	BANK OF AMERICA#32 · 360,396 sh	360,396	$5.8M	<0.01%	-1.6%
33	PRINCIPAL FINANCIAL GROUP#33 · 358,229 sh	358,229	$5.8M	<0.01%	+3.2%
34	Invesco Ltd.#34 · 260,612 sh	260,612	$4.2M	<0.01%	-1.2%
35	Velan Capital Investment Management#35 · 255,000 sh	255,000	$4.1M	2.50%	+2.0%
36	PUBLIC SECTOR PENSION INVESTMENT BOARD#36 · 254,741 sh	254,741	$4.1M	0.01%	-0.3%
37	ADAR1 Capital Management#37 · 232,560 sh	232,560	$3.7M	0.17%	+148.3%
38	Hudson Bay Capital Management#38 · 210,000 sh	210,000	$3.4M	<0.01%	-56.9%
39	BARCLAYS PLC#39 · 203,619 sh	203,619	$3.3M	<0.01%	-6.7%
40	NOMURA ASSET MANAGEMENT INTERNATIONAL#40 · 200,000 sh	200,000	$3.2M	<0.01%	0.0%
41	CITADEL ADVISORS#41 · 190,826 sh	190,826	$3.1M	<0.01%	-49.5%
42	RHUMBLINE ADVISERS#42 · 181,617 sh	181,617	$2.9M	<0.01%	+6.5%
43	AMERICAN CENTURY COMPANIES#43 · 180,205 sh	180,205	$2.9M	<0.01%	+2.9%
44	CITIGROUP#44 · 167,189 sh	167,189	$2.7M	<0.01%	+60.3%
45	JPMORGAN CHASE#45 · 167,089 sh	167,089	$2.6M	<0.01%	-17.2%
46	Susquehanna Portfolio Strategies#46 · 159,584 sh	159,584	$2.6M	0.04%	+15.5%
47	KORNITZER CAPITAL MANAGEMENT#47 · 151,410 sh	151,410	$2.4M	0.05%	New
48	Trexquant Investment#48 · 144,555 sh	144,555	$2.3M	0.01%	+224.9%
49	Nuveen#49 · 139,370 sh	139,370	$2.2M	<0.01%	+3.4%
50	Jump Financial#50 · 131,000 sh	131,000	$2.1M	0.02%	+1143.9%
51	HSBC PLC#51 · 125,482 sh	125,482	$2.1M	<0.01%	+114.2%
52	AMERIPRISE FINANCIAL#52 · 124,368 sh	124,368	$2.0M	<0.01%	-3.3%
53	DEUTSCHE BANK AG\#53 · 119,822 sh	119,822	$1.9M	<0.01%	-46.4%
54	FMR#54 · 119,745 sh	119,745	$1.9M	<0.01%	+7.0%
55	OP Asset Management Ltd#55 · 110,055 sh	110,055	$1.8M	0.02%	+99.8%
56	XTX Topco Ltd#56 · 107,377 sh	107,377	$1.7M	0.02%	+16.6%
57	WINTON GROUP Ltd#57 · 106,247 sh	106,247	$1.7M	0.06%	+1.5%
58	DCF Advisers#58 · 103,736 sh	103,736	$1.7M	0.30%	0.0%
59	Essex#59 · 98,661 sh	98,661	$1.6M	—	0.0%
60	Swiss National Bank#60 · 92,000 sh	92,000	$1.5M	<0.01%	-6.9%
61	Quinn Opportunity Partners#61 · 90,000 sh	90,000	$1.4M	0.07%	+200.0%
62	Erste Asset Management GmbH#62 · 92,200 sh	92,200	$1.4M	0.01%	-78.6%
63	VOLORIDGE INVESTMENT MANAGEMENT#63 · 80,736 sh	80,736	$1.3M	<0.01%	-21.6%
64	RAYMOND JAMES FINANCIAL#64 · 75,105 sh	75,105	$1.2M	<0.01%	+169.4%
65	PRUDENTIAL FINANCIAL#65 · 74,870 sh	74,870	$1.2M	<0.01%	+0.9%
66	ALPS ADVISORS#66 · 74,646 sh	74,646	$1.2M	<0.01%	+25.0%
67	HRT FINANCIAL#67 · 74,615 sh	74,615	$1.2M	<0.01%	+25.0%
68	ALLIANCEBERNSTEIN L.P.#68 · 97,790 sh	97,790	$1.2M	<0.01%	+35.6%
69	TUDOR INVESTMENT ET AL#69 · 72,917 sh	72,917	$1.2M	<0.01%	+66.4%
70	Point72 Asset Management, L.P.#70 · 71,572 sh	71,572	$1.2M	<0.01%	New
71	NEW YORK STATE TEACHERS RETIREMENT SYSTEM#71 · 70,526 sh	70,526	$1.1M	—	+3.4%
72	BNP PARIBAS FINANCIAL MARKETS#72 · 70,241 sh	70,241	$1.1M	<0.01%	+222.4%
73	SG Americas Securities#73 · 68,168 sh	68,168	$1.1M	<0.01%	+0.9%
74	ACADIAN ASSET MANAGEMENT#74 · 67,854 sh	67,854	$1.1M	<0.01%	-76.7%
75	TD ASSET MANAGEMENT#75 · 62,174 sh	62,174	$1.0M	<0.01%	0.0%
76	WELLS FARGO & COMPANY#76 · 60,837 sh	60,837	$979.5K	<0.01%	+123.4%
77	THRIVENT FINANCIAL FOR LUTHERANS#77 · 59,716 sh	59,716	$961.0K	<0.01%	-2.5%
78	Man Group plc#78 · 58,380 sh	58,380	$939.9K	<0.01%	-37.7%
79	GREAT WEST LIFE ASSURANCE#79 · 57,164 sh	57,164	$921.0K	<0.01%	0.0%
80	Rafferty Asset Management#80 · 53,920 sh	53,920	$868.1K	<0.01%	-28.7%
81	Quantinno Capital Management#81 · 53,494 sh	53,494	$861.3K	<0.01%	-6.3%
82	D. E. Shaw#82 · 50,475 sh	50,475	$812.6K	<0.01%	New
83	MANUFACTURERS LIFE INSURANCE COMPANY, THE#83 · 49,696 sh	49,696	$800.1K	<0.01%	-38.6%
84	Russell Investments Group, Ltd.#84 · 45,380 sh	45,380	$730.6K	<0.01%	-45.0%
85	SUSQUEHANNA INTERNATIONAL GROUP, LLP#85 · 44,403 sh	44,403	$714.9K	<0.01%	+58.4%
86	FRANKLIN RESOURCES#86 · 43,841 sh	43,841	$705.8K	<0.01%	+6.5%
87	Inspire Investing#87 · 41,642 sh	41,642	$670.4K	—	-2.1%
88	MetLife Investment Management#88 · 40,614 sh	40,614	$653.9K	<0.01%	+2.3%
89	Cerity Partners#89 · 39,929 sh	39,929	$642.9K	<0.01%	+30.9%
90	MIRAE ASSET GLOBAL ETFS Ltd.#90 · 38,193 sh	38,193	$611.8K	<0.01%	-0.2%
91	Palumbo Wealth Management#91 · 37,540 sh	37,540	$604.4K	0.13%	+110.8%
92	GSA CAPITAL PARTNERS LLP#92 · 34,520 sh	34,520	$556.0K	0.04%	-67.6%
93	EntryPoint Capital#93 · 32,752 sh	32,752	$527.3K	0.13%	+29.5%
94	Louisiana State Employees Retirement System#94 · 32,500 sh	32,500	$523.3K	—	+2.5%
95	VANGUARD ASSET MANAGEMENT, Ltd#95 · 31,393 sh	31,393	$505.4K	<0.01%	0.0%
96	LPL Financial#96 · 30,839 sh	30,839	$496.5K	<0.01%	+49.4%
97	PROFUND ADVISORS#97 · 29,616 sh	29,616	$476.8K	0.01%	-19.6%
98	State of Tennessee, Treasury Department#98 · 29,363 sh	29,363	$472.7K	<0.01%	+5.1%
99	Squarepoint Ops#99 · 28,507 sh	28,507	$459.0K	<0.01%	New
100	Vanguard Global Advisers#100 · 27,626 sh	27,626	$444.8K	<0.01%	0.0%

Funds that sold out of XNCR in Q2 2026 (24)

Held XNCR at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held XNCR in Q1 2026 and reported no position in Q2 2026.
Institution	Shares sold	Value in Q1 2026
EcoR1 Capital2,183,000 sh	2,183,000	$26.3M
JACOBS LEVY EQUITY MANAGEMENT293,080 sh	293,080	$3.5M
Nantahala Capital Management264,639 sh	264,639	$3.2M
ALGERT GLOBAL80,490 sh	80,490	$971.0K
DRW Securities48,442 sh	48,442	$584.2K
ExodusPoint Capital Management48,073 sh	48,073	$579.8K
Campbell & Investment Adviser43,526 sh	43,526	$524.9K
Linden Thomas Advisory Services42,084 sh	42,084	$507.5K
Qube Research & Technologies Ltd20,995 sh	20,995	$253.2K
RENAISSANCE TECHNOLOGIES18,723 sh	18,723	$225.8K
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS17,659 sh	17,659	$213.0K
Sanctuary Advisors13,963 sh	13,963	$168.4K
Centiva Capital12,299 sh	12,299	$148.3K
QUADRANT CAPITAL GROUP1,276 sh	1,276	$56.7K
FEDERATED HERMES2,059 sh	2,059	$24.8K
BNP Paribas Asset Management Holding S.A.974 sh	974	$11.7K
Quantbot Technologies701 sh	701	$8.5K
TWIN PEAKS WEALTH ADVISORS98 sh	98	$1.2K
Sound Income Strategies43 sh	43	$539.00
MAI Capital Management29 sh	29	$350.00
Advisory Services Network21 sh	21	$253.00
Wealth Preservation Advisors20 sh	20	$241.00
Abound Wealth Management6 sh	6	$73.00
Freestone Grove Partners1 sh	1	$12.00

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.